SMT201600073B - Inibitori della mitosi per aumentare l'apoptosi in terapia - Google Patents

Inibitori della mitosi per aumentare l'apoptosi in terapia

Info

Publication number
SMT201600073B
SMT201600073B SM201600073T SM201600073T SMT201600073B SM T201600073 B SMT201600073 B SM T201600073B SM 201600073 T SM201600073 T SM 201600073T SM 201600073 T SM201600073 T SM 201600073T SM T201600073 B SMT201600073 B SM T201600073B
Authority
SM
San Marino
Prior art keywords
mythosis
inhibitors
therapy
increase apoptosis
apoptosis
Prior art date
Application number
SM201600073T
Other languages
English (en)
Inventor
Brian J Tunquist
Duncan H Walker
Richard Donald Woessner
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of SMT201600073B publication Critical patent/SMT201600073B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433Thidiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SM201600073T 2008-10-16 2016-03-14 Inibitori della mitosi per aumentare l'apoptosi in terapia SMT201600073B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10608608P 2008-10-16 2008-10-16
PCT/US2009/061106 WO2010045624A1 (en) 2008-10-16 2009-10-16 Inhibitors of mitosis for increasing apoptosis in therapy

Publications (1)

Publication Number Publication Date
SMT201600073B true SMT201600073B (it) 2016-04-29

Family

ID=41508147

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201600073T SMT201600073B (it) 2008-10-16 2016-03-14 Inibitori della mitosi per aumentare l'apoptosi in terapia

Country Status (20)

Country Link
EP (1) EP2349259B1 (it)
JP (2) JP5749170B2 (it)
CN (2) CN102256603B (it)
AU (1) AU2009305588B2 (it)
BR (1) BRPI0920878A2 (it)
CA (1) CA2741069C (it)
CY (1) CY1117281T1 (it)
DK (1) DK2349259T3 (it)
ES (1) ES2565778T3 (it)
HK (1) HK1154813A1 (it)
HR (1) HRP20160267T1 (it)
HU (1) HUE027170T2 (it)
IL (1) IL212413A (it)
PL (1) PL2349259T3 (it)
RS (1) RS54647B1 (it)
RU (1) RU2519145C2 (it)
SI (1) SI2349259T1 (it)
SM (1) SMT201600073B (it)
UA (1) UA106214C2 (it)
WO (1) WO2010045624A1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2349259T3 (en) * 2008-10-16 2016-02-29 Array Biopharma Inc MITOSE INHIBITORS TO INCREASE APOPTOSE IN THERAPY
TWI427054B (zh) * 2012-01-20 2014-02-21 Nat Univ Chung Hsing A pharmaceutical composition for inhibiting and treating a lung tumor and inhibiting an inflammatory reaction and a method for preparing the same
EP2882436A1 (en) * 2012-08-13 2015-06-17 Array Biopharma, Inc. Arry-520 for use in treating cancer in a patient with low aag
AU2014227478A1 (en) 2013-08-08 2015-02-26 Array Biopharma Inc. Filanesib combined with pomalidomide displays enhanced anti-tumor activity
US11761951B2 (en) 2015-02-04 2023-09-19 Bristol-Myers Squibb Company Methods of selecting therapeutic molecules
JP7340240B2 (ja) * 2019-08-26 2023-09-07 学校法人関西医科大学 細胞又は組織にアポトーシスを誘導する方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1641777A1 (de) * 2003-06-05 2006-04-05 Zentaris GmbH Indolderivate mit apoptose induzierender wirkung
US7449486B2 (en) * 2004-10-19 2008-11-11 Array Biopharma Inc. Mitotic kinesin inhibitors and methods of use thereof
DK2349259T3 (en) * 2008-10-16 2016-02-29 Array Biopharma Inc MITOSE INHIBITORS TO INCREASE APOPTOSE IN THERAPY

Also Published As

Publication number Publication date
EP2349259A1 (en) 2011-08-03
ES2565778T3 (es) 2016-04-06
WO2010045624A1 (en) 2010-04-22
CN104958292A (zh) 2015-10-07
AU2009305588B2 (en) 2015-08-13
CY1117281T1 (el) 2017-04-26
EP2349259B1 (en) 2015-12-23
JP2014144979A (ja) 2014-08-14
JP2012505924A (ja) 2012-03-08
CA2741069A1 (en) 2010-04-22
IL212413A (en) 2015-08-31
UA106214C2 (ru) 2014-08-11
CN102256603A (zh) 2011-11-23
BRPI0920878A2 (pt) 2015-12-22
IL212413A0 (en) 2011-06-30
HRP20160267T1 (hr) 2016-04-08
JP5749170B2 (ja) 2015-07-15
RU2011119427A (ru) 2012-11-27
SI2349259T1 (sl) 2016-03-31
RS54647B1 (en) 2016-08-31
HUE027170T2 (hu) 2016-10-28
PL2349259T3 (pl) 2016-07-29
RU2519145C2 (ru) 2014-06-10
CA2741069C (en) 2017-08-22
CN104958292B (zh) 2018-10-16
DK2349259T3 (en) 2016-02-29
AU2009305588A1 (en) 2010-04-22
HK1154813A1 (zh) 2012-05-04
CN102256603B (zh) 2015-06-03

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