SMT201500064B - Trattamento antipsicotico basato su genotipo snp drd2 o ankk1 - Google Patents

Trattamento antipsicotico basato su genotipo snp drd2 o ankk1

Info

Publication number
SMT201500064B
SMT201500064B SM201500064T SM201500064T SMT201500064B SM T201500064 B SMT201500064 B SM T201500064B SM 201500064 T SM201500064 T SM 201500064T SM 201500064 T SM201500064 T SM 201500064T SM T201500064 B SMT201500064 B SM T201500064B
Authority
SM
San Marino
Prior art keywords
ankk1
drd2
treatment based
snp genotype
antipsychotic treatment
Prior art date
Application number
SM201500064T
Other languages
English (en)
Italian (it)
Inventor
Christian Lavedan
Simona Volpi
Original Assignee
Vanda Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vanda Pharmaceuticals Inc filed Critical Vanda Pharmaceuticals Inc
Publication of SMT201500064B publication Critical patent/SMT201500064B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
SM201500064T 2009-05-15 2015-03-16 Trattamento antipsicotico basato su genotipo snp drd2 o ankk1 SMT201500064B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17893409P 2009-05-15 2009-05-15

Publications (1)

Publication Number Publication Date
SMT201500064B true SMT201500064B (it) 2015-07-09

Family

ID=42555548

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500064T SMT201500064B (it) 2009-05-15 2015-03-16 Trattamento antipsicotico basato su genotipo snp drd2 o ankk1

Country Status (7)

Country Link
US (3) US9057104B2 (xx)
EP (1) EP2430183B1 (xx)
JP (3) JP2012526562A (xx)
CA (1) CA2760474C (xx)
ES (1) ES2533091T3 (xx)
SM (1) SMT201500064B (xx)
WO (1) WO2010132866A1 (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140255930A1 (en) * 2011-09-08 2014-09-11 Ohio State Innovation Foundation Materials and Methods Related to Dopamine Dysregulation Disorders
AU2013232014B2 (en) 2012-03-14 2016-06-16 Vanda Pharmaceuticals Inc. An iloperidone metabolite for use in the treatment of psychiatric disorders
ES2870498T3 (es) * 2015-02-17 2021-10-27 Vanda Pharmaceuticals Inc Iloperidona para el tratamiento de esquizofrenia
CN106434678A (zh) * 2016-08-30 2017-02-22 张建华 一个青春型精神分裂症关联基因
JP6935079B2 (ja) * 2017-05-09 2021-09-15 国立大学法人千葉大学 機能的snpの組合せ解析
US11214827B2 (en) * 2018-08-30 2022-01-04 Vanda Pharmaceuticals Inc. Genetic markers for enhancing efficacy of antipsychotic treatment with iloperidone
WO2020111169A1 (ja) * 2018-11-28 2020-06-04 国立大学法人千葉大学 多因子遺伝疾患の遺伝子検査法、及び検査キット

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1458888E (pt) * 2001-12-10 2011-06-01 Novartis Ag Métodos para tratar a psicose e a esquizofrenia baseados em polimorfismos no gene do cntf
WO2005007871A2 (en) 2003-07-08 2005-01-27 The Regents Of The University Of California Genetic marker of response to atypical antipsychotics and antidepressants and methods for use thereof
CA3113166A1 (en) * 2004-09-30 2006-04-13 Vanda Pharmaceuticals Inc. Methods for the administration of iloperidone
EP2152917B1 (en) * 2007-05-18 2016-03-23 Vanda Pharmaceuticals Inc. Genetic markers for efficacy of iloperidone in the treatment of psychotic symptoms
CA2699786C (en) 2007-09-10 2019-08-13 Vanda Pharmaceuticals, Inc. Antipsychotic treatment based on snp genotype

Also Published As

Publication number Publication date
CA2760474A1 (en) 2010-11-18
EP2430183A1 (en) 2012-03-21
US20150315648A1 (en) 2015-11-05
US9057104B2 (en) 2015-06-16
JP6528158B2 (ja) 2019-06-12
EP2430183B1 (en) 2014-12-17
JP2018046829A (ja) 2018-03-29
CA2760474C (en) 2020-08-18
JP6286696B2 (ja) 2018-03-07
US9408839B2 (en) 2016-08-09
WO2010132866A1 (en) 2010-11-18
ES2533091T3 (es) 2015-04-07
US20160166561A1 (en) 2016-06-16
JP2012526562A (ja) 2012-11-01
JP2016116524A (ja) 2016-06-30
US9243295B2 (en) 2016-01-26
US20120053207A1 (en) 2012-03-01

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