SK7172003A3 - Microparticles with an improved release profile and method for the production thereof - Google Patents
Microparticles with an improved release profile and method for the production thereof Download PDFInfo
- Publication number
- SK7172003A3 SK7172003A3 SK717-2003A SK7172003A SK7172003A3 SK 7172003 A3 SK7172003 A3 SK 7172003A3 SK 7172003 A SK7172003 A SK 7172003A SK 7172003 A3 SK7172003 A3 SK 7172003A3
- Authority
- SK
- Slovakia
- Prior art keywords
- microparticles
- release
- hours
- active substance
- active ingredient
- Prior art date
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- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- 229960003726 vasopressin Drugs 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
- 239000008307 w/o/w-emulsion Substances 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2000161944 DE10061944A1 (de) | 2000-12-13 | 2000-12-13 | Mikropartikel mit verbessertem Freisetzungsprofil |
| DE2001118160 DE10118160A1 (de) | 2001-04-11 | 2001-04-11 | Chitosan enthaltende Mikropartikel |
| PCT/EP2001/014515 WO2002047664A2 (de) | 2000-12-13 | 2001-12-11 | Mikropartikel mit verbessertem freisetzungsprofil und verfahren zu deren herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK7172003A3 true SK7172003A3 (en) | 2004-05-04 |
Family
ID=26007947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK717-2003A SK7172003A3 (en) | 2000-12-13 | 2001-12-11 | Microparticles with an improved release profile and method for the production thereof |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20040115277A1 (ru) |
| EP (1) | EP1341522B1 (ru) |
| JP (1) | JP2004515527A (ru) |
| AT (1) | ATE309788T1 (ru) |
| AU (2) | AU3323902A (ru) |
| BG (1) | BG107885A (ru) |
| BR (1) | BR0116077A (ru) |
| CA (1) | CA2431285A1 (ru) |
| CY (1) | CY1105442T1 (ru) |
| CZ (1) | CZ20031559A3 (ru) |
| DE (1) | DE50108114D1 (ru) |
| DK (1) | DK1341522T3 (ru) |
| EE (1) | EE200300279A (ru) |
| ES (1) | ES2250502T3 (ru) |
| HK (1) | HK1054689A1 (ru) |
| HU (1) | HUP0302363A3 (ru) |
| NO (1) | NO20032657L (ru) |
| PL (1) | PL363716A1 (ru) |
| RU (1) | RU2291686C2 (ru) |
| SK (1) | SK7172003A3 (ru) |
| WO (1) | WO2002047664A2 (ru) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1761249A1 (en) * | 2004-06-28 | 2007-03-14 | Cornell Research Foundation, Inc. | Injectable microspheres from unsaturated functionalized polyhydric alcohol esters |
| GB0416328D0 (en) * | 2004-07-21 | 2004-08-25 | Univ Cardiff | Use of dry powder compositions for pulmonary delivery |
| EP1679065A1 (en) | 2005-01-07 | 2006-07-12 | OctoPlus Sciences B.V. | Controlled release compositions for interferon based on PEGT/PBT block copolymers |
| US8628701B2 (en) * | 2006-10-31 | 2014-01-14 | Xavier University Of Louisiana | Method of micro-encapsulation |
| UA90013C2 (ru) * | 2008-03-19 | 2010-03-25 | Давид Анатолійович Нога | Фармацевтическая композиция, содержащая инсулин, и способ его получения |
| WO2011163469A1 (en) | 2010-06-23 | 2011-12-29 | Teva Pharmaceutical Industries Ltd. | Hydrated form of anti-inflammatory roflumilast-n-oxide |
| PL2790675T3 (pl) * | 2011-12-14 | 2019-12-31 | Abraxis Bioscience, Llc | Zastosowanie polimerowych rozczynników do liofilizacji lub zamrażania cząstek |
| US9308172B2 (en) * | 2012-10-26 | 2016-04-12 | Board Of Trustees Of Michigan State University | Device and method for encapsulation of hydrophilic materials |
| WO2014169816A1 (zh) * | 2013-04-18 | 2014-10-23 | 山东绿叶制药有限公司 | 戈舍瑞林缓释微球药物组合物 |
| DK3021873T3 (en) | 2013-07-18 | 2018-12-17 | Xalud Therapeutics Inc | Composition for the treatment of inflammatory joint disease |
| WO2015024759A1 (en) * | 2013-08-21 | 2015-02-26 | Evonik Industries Ag | Process for preparing redispersible powders of water-insoluble, biodegradable polyesters |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3116311B2 (ja) * | 1990-06-13 | 2000-12-11 | エーザイ株式会社 | マイクロスフィアの製法 |
| IT1243390B (it) * | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
| DE4201179A1 (de) * | 1992-01-17 | 1993-07-22 | Alfatec Pharma Gmbh | Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung |
| ATE188375T1 (de) * | 1992-11-17 | 2000-01-15 | Yoshitomi Pharmaceutical | Ein antipsychotikum enthaltende mikrokugel zur verzögerten freisetzung und verfahren für ihre herstellung |
| FR2702968B1 (fr) * | 1993-03-23 | 1995-06-23 | Lafon Labor | Procédé de préparation de particules renfermant un ingrédient actif par extrusion et lyophilisation . |
| WO1994023699A1 (en) * | 1993-04-19 | 1994-10-27 | Medisorb Technologies International L.P. | Long-acting treatment by slow-release delivery of antisense oligodeoxyribonucleotides from biodegradable microparticles |
| US5942253A (en) * | 1995-10-12 | 1999-08-24 | Immunex Corporation | Prolonged release of GM-CSF |
| CA2213906A1 (en) * | 1996-09-23 | 1998-03-23 | Dusica Maysinger | Pharmaceutical composition and method for neuron rescue in ischemic stroke |
| KR100289471B1 (ko) * | 1998-01-19 | 2001-09-17 | 김충섭 | 휀타닐계마취제의이식형서방성제제 |
| US6194006B1 (en) * | 1998-12-30 | 2001-02-27 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of microparticles having a selected release profile |
| EP1044683A1 (en) * | 1999-04-15 | 2000-10-18 | Debio Recherche Pharmaceutique S.A. | One-step dispersion method for the microencapsulation of water soluble substances |
-
2001
- 2001-12-11 CZ CZ20031559A patent/CZ20031559A3/cs unknown
- 2001-12-11 EE EEP200300279A patent/EE200300279A/xx unknown
- 2001-12-11 ES ES01984822T patent/ES2250502T3/es not_active Expired - Lifetime
- 2001-12-11 AU AU3323902A patent/AU3323902A/xx active Pending
- 2001-12-11 DK DK01984822T patent/DK1341522T3/da active
- 2001-12-11 CA CA002431285A patent/CA2431285A1/en not_active Abandoned
- 2001-12-11 HU HU0302363A patent/HUP0302363A3/hu unknown
- 2001-12-11 US US10/450,407 patent/US20040115277A1/en not_active Abandoned
- 2001-12-11 SK SK717-2003A patent/SK7172003A3/sk unknown
- 2001-12-11 DE DE50108114T patent/DE50108114D1/de not_active Expired - Lifetime
- 2001-12-11 RU RU2003117366/15A patent/RU2291686C2/ru not_active IP Right Cessation
- 2001-12-11 EP EP01984822A patent/EP1341522B1/de not_active Expired - Lifetime
- 2001-12-11 BR BR0116077-0A patent/BR0116077A/pt not_active Application Discontinuation
- 2001-12-11 AT AT01984822T patent/ATE309788T1/de not_active IP Right Cessation
- 2001-12-11 AU AU2002233239A patent/AU2002233239B2/en not_active Ceased
- 2001-12-11 WO PCT/EP2001/014515 patent/WO2002047664A2/de not_active Application Discontinuation
- 2001-12-11 JP JP2002549238A patent/JP2004515527A/ja active Pending
- 2001-12-11 PL PL01363716A patent/PL363716A1/xx unknown
-
2003
- 2003-06-06 BG BG107885A patent/BG107885A/bg unknown
- 2003-06-12 NO NO20032657A patent/NO20032657L/no not_active Application Discontinuation
- 2003-09-27 HK HK03107001A patent/HK1054689A1/xx not_active IP Right Cessation
-
2006
- 2006-01-19 CY CY20061100073T patent/CY1105442T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002047664A3 (de) | 2002-12-27 |
| CZ20031559A3 (cs) | 2004-03-17 |
| HK1054689A1 (en) | 2003-12-12 |
| JP2004515527A (ja) | 2004-05-27 |
| HUP0302363A3 (en) | 2006-07-28 |
| ES2250502T3 (es) | 2006-04-16 |
| ATE309788T1 (de) | 2005-12-15 |
| AU3323902A (en) | 2002-06-24 |
| RU2291686C2 (ru) | 2007-01-20 |
| EP1341522A2 (de) | 2003-09-10 |
| PL363716A1 (en) | 2004-11-29 |
| EP1341522B1 (de) | 2005-11-16 |
| WO2002047664A2 (de) | 2002-06-20 |
| EE200300279A (et) | 2003-10-15 |
| NO20032657L (no) | 2003-07-18 |
| US20040115277A1 (en) | 2004-06-17 |
| WO2002047664A8 (de) | 2004-03-04 |
| DE50108114D1 (de) | 2005-12-22 |
| CA2431285A1 (en) | 2002-06-20 |
| NO20032657D0 (no) | 2003-06-12 |
| BR0116077A (pt) | 2004-02-17 |
| HUP0302363A2 (hu) | 2003-10-28 |
| DK1341522T3 (da) | 2006-02-13 |
| CY1105442T1 (el) | 2010-04-28 |
| AU2002233239B2 (en) | 2006-05-11 |
| BG107885A (bg) | 2004-01-30 |
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