BR0116077A - Micropartìculas com perfil de liberação aperfeiçoado e processos para produção das mesmas - Google Patents
Micropartìculas com perfil de liberação aperfeiçoado e processos para produção das mesmasInfo
- Publication number
- BR0116077A BR0116077A BR0116077-0A BR0116077A BR0116077A BR 0116077 A BR0116077 A BR 0116077A BR 0116077 A BR0116077 A BR 0116077A BR 0116077 A BR0116077 A BR 0116077A
- Authority
- BR
- Brazil
- Prior art keywords
- microparticles
- release profile
- production processes
- improved release
- processes
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"MICROPARTìCULAS COM PERFIL DE LIBERAçãO APERFEIçOADO E PROCESSOS PARA PRODUçãO DAS MESMAS". A presente invenção refere-se a micropartículas para a liberação retardada de uma substância fisiologicamente ativa, que contêm pelo menos uma substância ativa e uma matriz polimérica. As micropartículas de acordo com a invenção possuem uma característica de liberação particularmente vantajosa. A invenção refere-se também a processos para produção dessas micropartículas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2000161944 DE10061944A1 (de) | 2000-12-13 | 2000-12-13 | Mikropartikel mit verbessertem Freisetzungsprofil |
DE2001118160 DE10118160A1 (de) | 2001-04-11 | 2001-04-11 | Chitosan enthaltende Mikropartikel |
PCT/EP2001/014515 WO2002047664A2 (de) | 2000-12-13 | 2001-12-11 | Mikropartikel mit verbessertem freisetzungsprofil und verfahren zu deren herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0116077A true BR0116077A (pt) | 2004-02-17 |
Family
ID=26007947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0116077-0A BR0116077A (pt) | 2000-12-13 | 2001-12-11 | Micropartìculas com perfil de liberação aperfeiçoado e processos para produção das mesmas |
Country Status (21)
Country | Link |
---|---|
US (1) | US20040115277A1 (pt) |
EP (1) | EP1341522B1 (pt) |
JP (1) | JP2004515527A (pt) |
AT (1) | ATE309788T1 (pt) |
AU (2) | AU3323902A (pt) |
BG (1) | BG107885A (pt) |
BR (1) | BR0116077A (pt) |
CA (1) | CA2431285A1 (pt) |
CY (1) | CY1105442T1 (pt) |
CZ (1) | CZ20031559A3 (pt) |
DE (1) | DE50108114D1 (pt) |
DK (1) | DK1341522T3 (pt) |
EE (1) | EE200300279A (pt) |
ES (1) | ES2250502T3 (pt) |
HK (1) | HK1054689A1 (pt) |
HU (1) | HUP0302363A3 (pt) |
NO (1) | NO20032657L (pt) |
PL (1) | PL363716A1 (pt) |
RU (1) | RU2291686C2 (pt) |
SK (1) | SK7172003A3 (pt) |
WO (1) | WO2002047664A2 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1976680A (zh) * | 2004-06-28 | 2007-06-06 | 康乃尔研究基金会有限公司 | 从不饱和官能化的多元醇酯得到的可注射微球 |
GB0416328D0 (en) * | 2004-07-21 | 2004-08-25 | Univ Cardiff | Use of dry powder compositions for pulmonary delivery |
EP1679065A1 (en) * | 2005-01-07 | 2006-07-12 | OctoPlus Sciences B.V. | Controlled release compositions for interferon based on PEGT/PBT block copolymers |
US8628701B2 (en) * | 2006-10-31 | 2014-01-14 | Xavier University Of Louisiana | Method of micro-encapsulation |
UA90013C2 (ru) | 2008-03-19 | 2010-03-25 | Давид Анатолійович Нога | Фармацевтическая композиция, содержащая инсулин, и способ его получения |
WO2011163469A1 (en) | 2010-06-23 | 2011-12-29 | Teva Pharmaceutical Industries Ltd. | Hydrated form of anti-inflammatory roflumilast-n-oxide |
PT2790675T (pt) | 2011-12-14 | 2019-09-23 | Abraxis Bioscience Llc | Utilização de excipientes poliméricos para a liofilização ou a congelação de partículas |
US9308172B2 (en) * | 2012-10-26 | 2016-04-12 | Board Of Trustees Of Michigan State University | Device and method for encapsulation of hydrophilic materials |
EP2987484B1 (en) * | 2013-04-18 | 2018-12-19 | Shandong Luye Pharmaceutical Co., Ltd. | Goserelin sustained release microsphere pharmaceutical composition |
RS59735B1 (sr) | 2013-07-18 | 2020-02-28 | Xalud Therapeutics Inc | Sastav za tretman upalnih bolesti zglobova |
WO2015024759A1 (en) * | 2013-08-21 | 2015-02-26 | Evonik Industries Ag | Process for preparing redispersible powders of water-insoluble, biodegradable polyesters |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3116311B2 (ja) * | 1990-06-13 | 2000-12-11 | エーザイ株式会社 | マイクロスフィアの製法 |
IT1243390B (it) * | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
DE4201179A1 (de) * | 1992-01-17 | 1993-07-22 | Alfatec Pharma Gmbh | Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung |
ATE188375T1 (de) * | 1992-11-17 | 2000-01-15 | Yoshitomi Pharmaceutical | Ein antipsychotikum enthaltende mikrokugel zur verzögerten freisetzung und verfahren für ihre herstellung |
FR2702968B1 (fr) * | 1993-03-23 | 1995-06-23 | Lafon Labor | Procédé de préparation de particules renfermant un ingrédient actif par extrusion et lyophilisation . |
CA2160877A1 (en) * | 1993-04-19 | 1994-10-27 | Michael David Amos | Long-acting treatment by slow-release delivery of antisense oligodeoxyribonucleotides from biodegradable microparticles |
US5942253A (en) * | 1995-10-12 | 1999-08-24 | Immunex Corporation | Prolonged release of GM-CSF |
CA2213906A1 (en) * | 1996-09-23 | 1998-03-23 | Dusica Maysinger | Pharmaceutical composition and method for neuron rescue in ischemic stroke |
KR100289471B1 (ko) * | 1998-01-19 | 2001-09-17 | 김충섭 | 휀타닐계마취제의이식형서방성제제 |
US6194006B1 (en) * | 1998-12-30 | 2001-02-27 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of microparticles having a selected release profile |
EP1044683A1 (en) * | 1999-04-15 | 2000-10-18 | Debio Recherche Pharmaceutique S.A. | One-step dispersion method for the microencapsulation of water soluble substances |
-
2001
- 2001-12-11 CZ CZ20031559A patent/CZ20031559A3/cs unknown
- 2001-12-11 AT AT01984822T patent/ATE309788T1/de not_active IP Right Cessation
- 2001-12-11 JP JP2002549238A patent/JP2004515527A/ja active Pending
- 2001-12-11 HU HU0302363A patent/HUP0302363A3/hu unknown
- 2001-12-11 AU AU3323902A patent/AU3323902A/xx active Pending
- 2001-12-11 PL PL01363716A patent/PL363716A1/xx unknown
- 2001-12-11 EP EP01984822A patent/EP1341522B1/de not_active Expired - Lifetime
- 2001-12-11 RU RU2003117366/15A patent/RU2291686C2/ru not_active IP Right Cessation
- 2001-12-11 SK SK717-2003A patent/SK7172003A3/sk unknown
- 2001-12-11 ES ES01984822T patent/ES2250502T3/es not_active Expired - Lifetime
- 2001-12-11 BR BR0116077-0A patent/BR0116077A/pt not_active Application Discontinuation
- 2001-12-11 EE EEP200300279A patent/EE200300279A/xx unknown
- 2001-12-11 DK DK01984822T patent/DK1341522T3/da active
- 2001-12-11 AU AU2002233239A patent/AU2002233239B2/en not_active Ceased
- 2001-12-11 DE DE50108114T patent/DE50108114D1/de not_active Expired - Lifetime
- 2001-12-11 CA CA002431285A patent/CA2431285A1/en not_active Abandoned
- 2001-12-11 US US10/450,407 patent/US20040115277A1/en not_active Abandoned
- 2001-12-11 WO PCT/EP2001/014515 patent/WO2002047664A2/de not_active Application Discontinuation
-
2003
- 2003-06-06 BG BG107885A patent/BG107885A/bg unknown
- 2003-06-12 NO NO20032657A patent/NO20032657L/no not_active Application Discontinuation
- 2003-09-27 HK HK03107001A patent/HK1054689A1/xx not_active IP Right Cessation
-
2006
- 2006-01-19 CY CY20061100073T patent/CY1105442T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
BG107885A (bg) | 2004-01-30 |
ES2250502T3 (es) | 2006-04-16 |
EE200300279A (et) | 2003-10-15 |
US20040115277A1 (en) | 2004-06-17 |
JP2004515527A (ja) | 2004-05-27 |
HUP0302363A2 (hu) | 2003-10-28 |
CY1105442T1 (el) | 2010-04-28 |
AU3323902A (en) | 2002-06-24 |
DK1341522T3 (da) | 2006-02-13 |
WO2002047664A8 (de) | 2004-03-04 |
NO20032657L (no) | 2003-07-18 |
CZ20031559A3 (cs) | 2004-03-17 |
HUP0302363A3 (en) | 2006-07-28 |
SK7172003A3 (en) | 2004-05-04 |
EP1341522A2 (de) | 2003-09-10 |
WO2002047664A2 (de) | 2002-06-20 |
PL363716A1 (en) | 2004-11-29 |
CA2431285A1 (en) | 2002-06-20 |
NO20032657D0 (no) | 2003-06-12 |
EP1341522B1 (de) | 2005-11-16 |
ATE309788T1 (de) | 2005-12-15 |
AU2002233239B2 (en) | 2006-05-11 |
HK1054689A1 (en) | 2003-12-12 |
WO2002047664A3 (de) | 2002-12-27 |
RU2291686C2 (ru) | 2007-01-20 |
DE50108114D1 (de) | 2005-12-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11, 13 E 25 DA LPI |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |