SK287124B6 - Použitie antiprogestínu na prípravu liečiva - Google Patents

Použitie antiprogestínu na prípravu liečiva Download PDF

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Publication number
SK287124B6
SK287124B6 SK474-2003A SK4742003A SK287124B6 SK 287124 B6 SK287124 B6 SK 287124B6 SK 4742003 A SK4742003 A SK 4742003A SK 287124 B6 SK287124 B6 SK 287124B6
Authority
SK
Slovakia
Prior art keywords
antiprogestin
treatment
tumor
breast cancer
ovariectomy
Prior art date
Application number
SK474-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK4742003A3 (en
Inventor
Jens Hoffmann
Rosemarie Lichtner
Gerhard Siemeister
Martin Schneider
Ulrike Fuhrmann
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of SK4742003A3 publication Critical patent/SK4742003A3/sk
Publication of SK287124B6 publication Critical patent/SK287124B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK474-2003A 2000-10-18 2001-10-17 Použitie antiprogestínu na prípravu liečiva SK287124B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24099800P 2000-10-18 2000-10-18
EP00250341 2000-10-18
PCT/EP2001/012005 WO2002032430A1 (fr) 2000-10-18 2001-10-17 Utilisation d'antiprogestines pour la prevention et le traitement de maladies dependant des hormones

Publications (2)

Publication Number Publication Date
SK4742003A3 SK4742003A3 (en) 2004-09-08
SK287124B6 true SK287124B6 (sk) 2009-12-07

Family

ID=26072951

Family Applications (1)

Application Number Title Priority Date Filing Date
SK474-2003A SK287124B6 (sk) 2000-10-18 2001-10-17 Použitie antiprogestínu na prípravu liečiva

Country Status (26)

Country Link
US (1) US7378406B2 (fr)
EP (1) EP1328276B1 (fr)
JP (2) JP2004511522A (fr)
KR (1) KR100632908B1 (fr)
CN (1) CN1512886A (fr)
AT (1) ATE310522T1 (fr)
AU (2) AU1824302A (fr)
BG (1) BG107743A (fr)
BR (1) BR0114665A (fr)
CA (1) CA2423017C (fr)
CY (1) CY1104981T1 (fr)
CZ (1) CZ299942B6 (fr)
DE (1) DE60115274T2 (fr)
DK (1) DK1328276T3 (fr)
EE (1) EE05259B1 (fr)
ES (1) ES2253443T3 (fr)
HR (1) HRP20030387A2 (fr)
HU (1) HUP0301460A3 (fr)
IL (2) IL154975A0 (fr)
MX (1) MXPA03002954A (fr)
NO (1) NO20031740L (fr)
NZ (1) NZ538346A (fr)
PL (1) PL360151A1 (fr)
SI (1) SI1328276T1 (fr)
SK (1) SK287124B6 (fr)
WO (1) WO2002032430A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY27301A1 (es) * 2001-05-25 2003-02-28 Schering Ag Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata
DE10159217A1 (de) 2001-11-27 2003-06-05 Schering Ag 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
US9517240B2 (en) * 2006-09-26 2016-12-13 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
US20090029954A1 (en) * 2007-04-23 2009-01-29 Jens Hoffmann Progesterone-receptor antagonist for use in brca alone or as combination with antiestrogen
US20080268041A1 (en) * 2007-04-23 2008-10-30 Jens Hoffmann Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases
US20080261929A1 (en) * 2007-04-23 2008-10-23 Jens Hoffmann Combination of progesterone-receptor antagonist together with an aromatase inhibitor for use in brca mediated diseases
TWI539953B (zh) * 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
TWI477276B (zh) * 2008-04-28 2015-03-21 Repros Therapeutics Inc 抗黃體素給藥方案
DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034366A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de) 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102010007719A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
DE102010007722A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
US20130018027A1 (en) * 2010-03-22 2013-01-17 Repros Therapeutics Inc. Compositions and methods for non-toxic delivery of antiprogestins
SG10201704858PA (en) 2012-05-31 2017-07-28 Repros Therapeutics Inc Formulations and methods for vaginal delivery of antiprogestins
MX2015004821A (es) 2012-11-02 2015-08-14 Repros Therapeutics Inc Metodos y composiciones para tratar condiciones dependientes de la progesterona.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3733478A1 (de) * 1987-10-01 1989-04-13 Schering Ag Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore
DE19706061A1 (de) 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette

Also Published As

Publication number Publication date
DE60115274T2 (de) 2006-07-27
DK1328276T3 (da) 2006-04-03
DE60115274D1 (de) 2005-12-29
US20040048841A1 (en) 2004-03-11
IL154975A (en) 2007-05-15
CY1104981T1 (el) 2010-03-03
AU2002218243B2 (en) 2006-07-13
JP2010077158A (ja) 2010-04-08
SI1328276T1 (sl) 2006-04-30
MXPA03002954A (es) 2003-08-07
KR100632908B1 (ko) 2006-10-13
EP1328276B1 (fr) 2005-11-23
PL360151A1 (en) 2004-09-06
NO20031740D0 (no) 2003-04-15
HUP0301460A2 (hu) 2003-10-28
AU1824302A (en) 2002-04-29
BG107743A (bg) 2004-01-30
CA2423017A1 (fr) 2002-04-25
ES2253443T3 (es) 2006-06-01
BR0114665A (pt) 2004-01-13
JP2004511522A (ja) 2004-04-15
CZ299942B6 (cs) 2008-12-29
WO2002032430A1 (fr) 2002-04-25
ATE310522T1 (de) 2005-12-15
SK4742003A3 (en) 2004-09-08
CN1512886A (zh) 2004-07-14
KR20030044007A (ko) 2003-06-02
EP1328276A1 (fr) 2003-07-23
CA2423017C (fr) 2009-01-06
US7378406B2 (en) 2008-05-27
HRP20030387A2 (en) 2005-04-30
EE200300155A (et) 2003-08-15
EE05259B1 (et) 2010-02-15
IL154975A0 (en) 2003-10-31
NO20031740L (no) 2003-06-17
NZ538346A (en) 2007-03-30
HUP0301460A3 (en) 2010-01-28

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20101017