SK2752000A3 - Automatic fermetor for producing activated probiotics - Google Patents

Abstract

Device for fermentation of activated probiotics fermentation packs into which probiotics are filled manufacturer of probiotics and that uses data on the type of probiotics date of manufacture and the end date of probiotics activation for such a probiotic fermentation process. to be completed just in time for its application in the most effective form.

Description

Technical field:

The invention relates to an apparatus for activating and fermenting probiotics from probiotic microorganisms and from a culture medium directly to a user of activated probiotics.

BACKGROUND OF THE INVENTION:

Probiotics are most active in the fresh state and are difficult to produce by the end user, who is generally ignorant of microbiology and fermentation technology. The quality of the product can be strongly influenced by the fermentation process, the storage of the semi-finished product, but also by biological accidental phenomena in this field of biotechnology.

Therefore, during fermentation of the activated fresh probiotics, control of the fermentation process and the finished product is necessary.

These requirements are met by the production of probiotics in industry and laboratories with the necessary equipment and qualified personnel. The problem, however, is that the freshly activated probiotic can be considered to be a probiotic that is in the phase of proliferation of probiotic microorganisms, and this phase is so short that it is almost impossible to apply the freshly fermented probiotic in an industry or laboratory.

Currently, probiotics are distributed such that they are packaged as fresh probiotic products at the factory, or are stabilized mostly by cold (eg yoghurt), or are preserved and stabilized, for example, by lyophilization, drying, freezing but also chemically. Protection of probiotics by encapsulation is common. The product that is labeled fresh is generally in the phase of inhibiting the growth of microorganisms and these also need time to activate. Activation of probiotics by cultivation in conventional thermostats requires a certain degree of qualification, is uncomfortable and can produce non-standard results.

SUMMARY OF THE INVENTION:

The pros and cons. Terminology specification.

The application of probiotics in the activated fresh state is practically made possible by an automated fermenter whose essence is that probiotics are automatically prepared from preserved or stabilized probiotic microorganisms in a medium placed in a disposable fermentation vessel which is also a distribution container for probiotics. The automated system consists of a fermentation unit into which we place the fermentation vessel and a control unit. The units can be integrated into a single unit.

The fermentation unit consists of a container for the fermentation vessel, a cap, heating elements, a mixing device, sensors for evaluating the physical and chemical properties of the product and a sensor for identifying the activated probiotic.

The fermentation container is an integrated vessel that contains a water supply hose, a microbiological water filter, a probiotic in an automatically opened vial - ampoule, culture medium in the main part of the vessel, a venting and antifoam valve, and information for automatic content identification. The probiotic package is equipped to allow mixing and measurement without compromising the integrity of the sterile environment.

The probiotic will be inserted into a fermentation unit in a disposable fermentation container and connected by a tubing for connection to a water supply valve.

The control unit contains power sources, evaluation and control electronics including the software unit, status and error display, controls for setting production times and parameters, water supply valve and necessary cabling.

The control unit evaluates the probiotic data from the information on the fermenter or entered on the controls. Based on the product tip data and times, the fermentation shell is filled with water and fermentation is started so that the probiotic is activated in time.

During fermentation, the unit controls temperature, pH, conductivity, light absorption, haze, viscosity and the like. Based on this information, the control unit controls the fermentation process and, if necessary, reports error messages.

The apparatus allows the fermentation to proceed so as not to impair the sterility of the probiotics during or after the fermentation.

Example

1. Probiotics fermenter supplied by the manufacturer in disposable 1000 ml plastic fermentation containers. The fermentation unit and the control unit are integrated into a single device. The core of the control unit is an industrial computer equipped with AD and DA converters for communication with the fermentation unit. The software is special and non-editable by customers. The culture medium is mixed by vibration through the wall of the plastic fermentation shell. Fermenter is designed for defined products and type of fermentation containers.

2. Fermenter for experimental workplaces: The fermentation unit is adapted to different sizes of fermentation vessels. The control unit is designed by an industrial computer with control and measuring units. Multiple fermentation units can be controlled by one computer. The software is universal, designed for industrial measurement and control. This type of fermenter is intended for research workplaces and laboratories dealing with the development of activated probiotics. It is used to research fermentation processes and to develop software for fermentation of individual probiotic preparations.

3. How to use the fermenter: We use a universal fermenter made per 1000 ml of activated probiotic, which is adjusted to the fermentation vessels by a pharmaceutical company. The fermenter is used on the farm. The animal keeper puts the probiotic for weaning pigs into the fermentation unit, attaches it to the valve on the water source, sets the time when the probiotic is to be finished and closes the fermentation unit. The control unit automatically evaluates the entered information and initiates the fermentation process so that the probiotic is completed in the maximum effective phase of growth of the probiotic microorganisms, just in time for application to the pigs. After the fermentation is complete, the fermentation vessel is removed from the fermentation unit and the activated probiotic is applied to the piglets according to the instructions. The dose per piglet may be 1 - 5 ml of the preparation as the activated probiotic is very effective.

Claims (5)

Claims: An automated fermenter for the production of activated probiotics, characterized in that it ferments probiotics directly in packages in which the probiotic is distributed by the manufacturer. The fermenter controls the fermentation according to the product type and production date, along with when the product is to be finished so that the probiotic is optimally active just in time. 2. The algorithm for controlling the fermentation of individual probiotic products is characterized by being part or complement of the control unit software. 3. Entering the product information into the control unit is characterized by the fact that the product type and production date are read by the device on the product packaging or are entered via the controls. 4. Measurement of physical quantities and mixing of the culture medium during fermentation in an automated fermenter is characterized in that probiotics can be carried out without disturbing the envelope. 5. The water supply to the fermentation container is characterized in that it is carried out automatically from the water source through a microbial filter.