SI9110367A

SI9110367A - Inhalation device

Info

Publication number: SI9110367A
Application number: SI9110367A
Authority: SI
Inventors: Michael Birsha Davies; David John Hearne; Paul Kenneth Rand; Richard Ian Walker
Original assignee: Glaxo Group Ltd
Priority date: 1990-03-02
Filing date: 1991-03-01
Publication date: 1995-04-30
Also published as: HRP940631B1; HRP940631A2

Abstract

Opisana je inhalacijska naprava za uporabo s paketom (401) z zdravilom, v katerem je med dvema folijama (403, 404), ki sta druga z drugo luščljivo spojeni, definirana vsaj ena posodica (402) za zdravilo v obliki praška. Naprava obsega sredstva za lupilno razdvajanje folij na odpiralni postaji za odprtje posodice; in izpust (420), ki sodeluje z odprto posodico in skozi katerega uporabnik lahko vdihne zdravilo v obliki praška iz odprte posodice.An inhalation device for use with a pack (401) containing a medicament in which there is between two foils (403, 404), which are detached from each other fused, at least one drug container (402) defined in powder form. The apparatus comprises peeling agents separating the foils at the opening station to open the container; and discharge (420) interacting with the open container and through which the user can inhale the drug into powder form from an open container.

Description

GLAXO GROUP LIMITEDGLAXO GROUP LIMITED

INHALACUSKA NAPRAVAINHALATION DEVICE

Ta izum se nanaša na inhalacijsko napravo, s pomočjo katere uporabnik lahko vdihava zdravilo v obliki praška.The present invention relates to an inhalation device whereby a user can inhale a drug in powder form.

Znane so inhalacijske naprave za uporabo z embalažo v obliki paketa mehurjev (angl. blisterpack), v kateri je v vsakokratnem mehurju zajeto zdravilo v obliki prahu. Take naprave vsebujejo prehodni element, ki vsakokrat prebode zadevni mehur, s čimer je vzpostavljena možnost vdihniti zdravilo iz njega. Cilj pričujočega izuma je ustvariti inhalacijsko napravo, katere zasnova omogoča, če se to želi, delati s paketom zdravila, ki ima veliko število medsebojno ločenih enot doziranega sredstva, ne da bi naprava postala nesprejemljivo razsežna.Inhalation devices are known for use with blister packs containing the powder in each bladder. Such devices contain a transient element that permeates the bladder in question each time, thereby allowing the drug to be inhaled. It is an object of the present invention to provide an inhalation device, the design of which, if desired, allows it to work with a drug package having a large number of mutually separated units of dosage agent without making the device unacceptably large.

Po predloženem izumu je ustvarjena inhalacijska naprava za uporabo s paketom zdravila, v katerem je vsaj ena posodica za zdravilo v obliki praška določena med dvema elementoma, ki sta tako medsebojno povezana, da se dasta odluščiti, pri čemer naprava obsega sredstva, ki določajo odprto postajo za omenjeno vsaj eno posodico; sredstva za luščenje delov narazen na odpiralni postaji za odpiranje posodice; in izpust, ki sodeluje z odprto posodico, skozi katerega uporabnik lahko vdihne zdravilo v obliki praška iz odprte posodice.According to the present invention, an inhalation device for use with a medicament package is created, in which at least one powder container is defined between two elements so interconnected that it can be decided upon, the device comprising means that define an open station for said at least one container; means for peeling the parts apart at the opening station to open the container; and a discharge that cooperates with an open container through which the user can inhale the powder in the form of an open container powder.

Prednostno je paket zdravila narejen iz dveh podolgovatih folij, ki določata več posodic za zdravilo, razmaknjenih vzdolž njegove dolžine, pri čemer so predvidena sredstva za označevanje (indeksiranje) vsake posodice, ko je ta na odpiralni postaji.Preferably, the medicament package is made of two elongated foils that define several drug containers spaced along its length, with means for marking (indexing) each container when it is at the opening station.

Pri izumu gre tudi za ustvaritev paketa zdravila za uporabo pri inhalacijski napravi, pri čemer paket vsebuje podolgovat trak, narejen iz temeljne folije, ki ima več vdrtin, ki so razmaknjene vzdolž njegove dolžine, in krovno folijo, ki je k prvemu hermetično, vendar luščljivo priključena, tako da obstaja več posodic, od katerih vsaka vsebuje vdihljivo zdravilo v obliki praška. Trak je prednostno zadosti gibek, da se ga lahko zvije v zvitek.The invention also relates to the creation of a package of a medicament for use in an inhalation device, the package comprising an elongated strip made of a base foil having several indentations spaced along its length and a cover foil that is first hermetic but peelable connected so that there are several containers, each containing an inhalable powder form. The tape is preferably flexible enough to be rolled up.

V priloženih listih skic je sl. 1 prvi izvedbeni primer izuma v pogledu od zadaj, sl. 2 prostorska razstavitvena predstavitev sestavin izvedbenega primera s sl. 1, sl. 3a sklopka iz izvedbenega primera s sl. 1 in 2 v prostorski predstavitvi, sl. 3b sklopka iz izvedbenega primera s sl. 1 in 2 v vzdolžnem prerezu, sl. 3c sklopka iz izvedbenega primera s sl. 1 in 2 v pogledu skonca (z delnim odrezom), sl. 4a ustnični kos, ki se lahko uporablja v prvem izvedbenem primeru (ali v kakem drugem izvedbenem primeru), v osnem prerezu in v večjem merilu kot na skici sl. 1, sl. 4b ustnični kos, ki se lahko uporablja v prvem izvedbenem primeru (ali v kakem drugem izvedbenem primeru), v prečnem prerezu in v večjem merilu kot na skici sl. 1, sl. 5 drugi izvedbeni primer v pogledu od spredaj, pri čemer je pokrov odstranjen, da se vidi notranjost, sl. 6 drugi izvedbeni primer v pogledu od zadaj, ampak s predstavitvijo notranjosti naprave, sl. 7 drugi izvedbeni primer v pogledu od spredaj v prostorski predstavitvi, sl. 8 drugi izvedbeni primer v pogledu od zadaj v prostorski predstavitvi, sl. 9 drugi izvedbeni primer v prostorski razstavitveni predstavitvi, sl. 10 tretji izvedbeni primer v pogledu od spredaj in s predstavitvijo notranje zgradbe naprave, sl. 11 ustnični kos tretjega izvedbenega primera v osnem pogledu in v večjem merilu, sl. 12 tretji izvedbeni primer v pogledu od spodaj, sl. 13 četrti izvedbeni primer izuma v pogledu od spodaj, sl. 14 četrti izvedbeni primer izuma v prerezu po črti B-B s sl. 13, sl. 15 četrti izvedbeni primer izuma v prerezu po črti A-A s sl. 13, sl. 16 četrti izvedbeni primer izuma v razstavitveni predstavitvi in v manjšem merilu, sl. 16a prva faza delovanja četrtega izvedbenega primera izuma, sl. 16b druga faza delovanja četrtega izvedbenega primera izuma, sl. 16c tretja faza delovanja četrtega izvedbenega primera izuma, sl. 16d četrta faza delovanja četrtega izvedbenega primera izuma, sl. 16e prerez po črti A-A s sl. 16a, sl. 17 peti izvedbeni primer izuma v pogledu skonca, sl. 18 peti izvedbeni primer izuma v prerezu po črti A-A s sl. 17, sl. 19 peti izvedbeni primer izuma v prerezu po črti B-B s sl. 17, sl. 20 peti izvedbeni primer izuma v razstavitveni predstavitvi, sl. 21 šesti izvedbeni primer izuma v pogledu skonca, sl. 22 šesti izvedbeni primer izuma v prerezu po črti A-A s sl. 21, sl. 23 šesti izvedbeni primer izuma v prerezu po črti B-B s sl. 21, sl. 24 šesti izvedbeni primer izuma v razstavitveni predstavitvi, sl. 25 modificirana sklopka, ki jo lahko uporabimo v tistih izvedbenih primerih izuma, ki jo potrebujejo, v pogledu od spredaj, sl. 26 modificirana sklopka, ki jo lahko uporabimo v tistih izvedbenih primerih izuma, ki jo potrebujejo, v pogledu od zgoraj, sl. 27 modificirana sklopka, ki jo lahko uporabimo v tistih izvedbenih primerih izuma, ki jo potrebujejo, v pogledu od zadaj, sl. 28 modificirana sklopka, ki jo lahko uporabimo v tistih izvedbenih primerih izuma, ki jo potrebujejo, v pogledu z leve, sl. 29 modificirana sklopka, ki jo lahko uporabimo v tistih izvedbenih primerih izuma, ki jo potrebujejo, v prostorski predstavitvi, sl. 30 razstavitvena prostorska predstavitev, ki kaže nadaljnji izvedbeni primer sklopke, ki jo lahko uporabimo, sl. 31 razstavitvena prostorska predstavitev še nadaljnje izvedbe sklopke, ki jo lahko uporabimo, sl. 31a prečni presek čez sklopko, predstavljeno na sl. 31, sl. 32 prvi položaj delovanja nadaljnje izvedbe izuma, predstavljene v pogledu od zadaj, sl. 33 drugi položaj delovanja nadaljnje izvedbe izuma, predstavljene v pogledu od zadaj, sl. 34 tretji položaj delovanja nadaljnje izvedbe izuma, predstavljene v pogledu od zadaj, in sl. 35 izvedbeni primer paketa zdravila po izumu, predstavljen v prostorski predstavitvi in v večjem merilu.In the accompanying sketch sheets, FIG. 1 is a first embodiment of the invention in rear view; 2 is a spatial disassembly of the components of the embodiment of FIG. 1, FIG. 3a shows the clutch of the embodiment of FIG. 1 and 2 in the spatial representation, FIG. 3b shows the clutch of the embodiment of FIG. 1 and 2 in longitudinal section, FIG. 3c shows the clutch of the embodiment of FIG. 1 and 2 in view of the end (partial cut), FIG. 4a is an oral piece that can be used in the first embodiment (or in another embodiment), in axial section and on a larger scale than in FIG. 1, FIG. 4b is a lip piece that can be used in the first embodiment (or in another embodiment), in cross-section and on a larger scale than in FIG. 1, FIG. 5 is a second embodiment in front view, with the lid removed to see the interior, FIG. 6 is a second embodiment in rear view, but with a representation of the interior of the device, FIG. 7 is a second embodiment in front view of the spatial representation, FIG. 8 is a second embodiment in rear view of the spatial representation, FIG. 9 is a second embodiment in a spatial exhibition presentation, FIG. 10 is a third embodiment in front view and with a representation of the internal structure of the apparatus, FIG. 11 is an axial and bulk view of the third embodiment of the third embodiment, FIG. 12 is a third embodiment in the bottom view; FIG. 13 shows a fourth embodiment of the invention from the bottom, FIG. 14 is a fourth embodiment of the invention in cross-section along line B-B of FIG. 13, fig. 15 is a fourth embodiment of the invention in cross-section along line A-A of FIG. 13, fig. 16 is a fourth embodiment of the invention in an exploded view and on a smaller scale, FIG. 16a is a first stage of operation of the fourth embodiment of the invention, FIG. 16b the second stage of operation of the fourth embodiment of the invention, FIG. 16c is a third stage of operation of the fourth embodiment of the invention, FIG. 16d is a fourth stage of operation of the fourth embodiment of the invention, FIG. 16e is a cross-section along line A-A of FIG. 16a, FIG. 17 is a fifth embodiment of the invention in view of the end view, FIG. 18 is a fifth sectional view of the invention in cross-section along line A-A of FIG. 17, FIG. 19 shows a fifth embodiment of the invention in cross-section along line B-B of FIG. 17, FIG. 20 is a fifth embodiment of the invention in an exploded view, FIG. 21 is a sixth embodiment of the invention in view of the end view, FIG. 22 is a sixth embodiment of the invention in cross-section along line A-A of FIG. 21, fig. 23 is a sixth embodiment of the invention in cross-section along line B-B of FIG. 21, fig. FIG. 24 is a sixth embodiment of the invention in an exploded view; FIG. 25 is a modified clutch that can be used in those embodiments of the invention which need it, from the front view; 26 is a modified clutch that can be used in those embodiments of the invention that need it, from the top view; 27 is a modified clutch that can be used in those embodiments of the invention in need of rear view; 28 is a modified clutch that can be used in those embodiments of the invention which need it, from the left, FIG. 29 is a modified clutch that can be used in those embodiments of the invention that need it, in a spatial representation, FIG. 30 is a sectional view showing a further embodiment of a coupling that can be used; FIG. 31 is an exploded spatial representation of a further embodiment of the coupling that can be used; FIG. 31a is a cross-sectional view through the clutch shown in FIG. 31, fig. 32 is a first operating position of a further embodiment of the invention presented in rear view; 33 is another operating position of a further embodiment of the invention presented in rear view; 34 is a third operating position of a further embodiment of the invention presented in rear view, and FIG. 35 is an exemplary embodiment of a drug package of the invention presented in a spatial representation and on a larger scale.

Prehajamo na skice sl. 1, 2 in 3a do 3c, pri katerih gre za inhalacijsko napravo, v katero je vgrajen gibek trak 1, ki določa več žepkov 2, od katerih vsak vsebuje dozo zdravila, ki ga lahko vdihnemo, v obliki praška. Trak 1 vsebuje osnovno folijo 3, v kateri so narejeni mehurji, ki tvorijo žepke 2, in krovno folijo 4, ki je - razen v območju mehurjev - neprodušno spojena s temeljno folijo 3 na način, da se krovna folija in temeljna folija lahko luščilno ločita. Foliji sta medsebojno spojeni po svej svoji širini, razen na svojih vodilnih končnih delih, kjer prednostno medsebojno sploh nista spojeni. Tako krovna kot tudi osnovna folija sta prednostno narejeni iz laminata plastike in aluminija in krovna in osnovna folija sta medsebojno spojeni prednostno po načinu toplotnega sprijemanja. Kot primer navedimo, da je gradivo krovne folije lahko laminat, ki sestoji iz 50-gramskega/m² beljenega papirja vrste kraft/12mikronskega poliestrskega (PETP) filma/20-mikronske mehkožarjene aluminijske folije/9-gramskega/m² vinilno luščljivega laka za toplotno sprijemanje (sprijemljivega s PVC), osnovno gradivo pa je lahko laminat, ki sestoji iz 100-mikronskega PVC/45mikronske mehkožarjene aluminijske folije/25-mikronskega usmerjenega poliamida. Lak krovnega gradiva je spojen s PVC-plastjo gradiva osnovne folije, da nastane luščljiv spoj med krovno in osnovno folijo.We proceed to the sketches of FIG. 1, 2 and 3a through 3c, which is an inhalation device which incorporates a flexible strip 1 which defines several pockets 2, each containing a dose of inhalable drug in powder form. Tape 1 comprises a base foil 3 in which the pockets forming pockets 2 are made and a cover foil 4 which, except in the bladder area, is sealed with the base foil 3 in such a way that the cover foil and the base foil can be separated from each other. . The films are interconnected throughout their width, except at their leading end portions, where they are preferably not bonded at all. Both the base and base films are preferably made of plastic and aluminum laminate, and the base and base films are bonded to one another preferably by thermal adhesion. As an example, the cover film material may be laminate consisting of 50 g / m ² bleached kraft paper / 12 micron polyester (PETP) film / 20 micron soft-foil aluminum foil / 9 g / m ² vinyl peel lacquer thermal adhesion (PVC adhesive), the base material being laminate consisting of 100 micron PVC / 45 micron soft-annealed aluminum foil / 25 micron oriented polyamide. The lacquer material is bonded to the PVC layer of the base film material to form a peelable joint between the base film and the base film.

Predstavljen je trak 1, ki ima podolgovate žepke, ki potekajo prečno glede na dolžino traku. To je primerno zategadelj, ker je s tem omogočeno na dani dolžini traku narediti veliko število žepkov. Trak je naprimer lahko opremljen s šestdesetimi ali stotimi žepki, razumeti pa je treba, da ima trak lahko katero koli primerno število žepkov.Belt 1 is presented which has elongated pockets extending transversely to the length of the strip. This is appropriate because it allows a large number of pockets to be made at a given length of belt. For example, the strap may be provided with sixty or one hundred pockets, but it should be understood that the strap may have any suitable number of pockets.

Inhalacijska naprava vsebuje telo 10, ki določa tri shranjevalne komore, namreč komoro 11, v kateri trak sprva spravimo in iz katere se trak izdaja, komoro 12 za sprejem uporabljenega dela osnovne folije 3 in komoro 13, znotraj katere se porabljeni del krovne folije lahko navija na kolo 14. Komori 11 in 12 vsebujeta zadevni vzmeti 28 in 29 v obliki upognjenih listov, katerih namen je opisan spodaj. Telo določa nadaljnjo komoro 15, v kateri je spravljeno označevalno (indeksirno) kolo 16. Le-to ima več utorov 17, potekajočih vzporedno z osjo kolesa 16. Utori so razmaknjeni s korakom, ki je enak razdalji med središčnicama sosednih žepkov 2. Komore 11,12,13 in 15 pokriva pokrov 30. Komora 15 sodeluje s komorami 11, 12 in preko prehodov 31, 33 oziroma 32.The inhalation device comprises a body 10 which defines three storage chambers, namely a chamber 11 in which the tape is initially removed and from which the tape is released, a chamber 12 for receiving the used portion of the base film 3 and a chamber 13 within which the spent portion of the cover film can be wound to wheel 14. Chambers 11 and 12 comprise the curved springs in question 28 and 29, the purpose of which is described below. The body defines a further chamber 15 in which the marking (indexing) wheel is stored 16. It has several grooves 17 running parallel to the axis of the wheel 16. The grooves are spaced in a step equal to the distance between the center lines of the adjacent pockets 2. Chambers 11 , 12,13 and 15 cover lid 30. Chamber 15 cooperates with chambers 11, 12 and through passages 31, 33 and 32 respectively.

Komora 15 je povezana z režo 18, ki se na drugi strani izteka gor v ustnični kos 20. Reža 18 je tudi povezana z zračnimi vhodi, kot bo opisano spodaj v zvezi s posebnim ustničnim kosom, ki ga kažeta skici sl. 4a in 4b. Ustnični kos 20 ima dodatne zračne vhode 21, ki so tu ponazorjeni kot dvojica okroglih odprtin, dasiravno so lahko tudi drugačnih oblik, kot je to slučaj pri sl. 4a in 4b. Osnovni namen dodatnih zračnih vhodov 21 je poskrbeti za dodatni zrak za uporabnika in s tem zmanjšati upor vdihavanja, dasiravno le-ti lahko služijo enemu ali več dodatnim namenom, kot je to slučaj pri sl. 4a in 4b in kot je opisano spodaj v zvezi z omenjenima skicama.The chamber 15 is connected to a slot 18 extending upward into the lip 20 on the other side. The slot 18 is also connected to the air inlets, as will be described below in connection with the special lip piece shown in the drawings of FIG. 4a and 4b. The mouthpiece 20 has additional air inlets 21, which are illustrated here as two round openings, and may also be of different shapes, as is the case in FIG. 4a and 4b. The primary purpose of the auxiliary air inlets 21 is to provide additional air for the user and thereby reduce the inhalation resistance, so that they can serve one or more additional purposes, as is the case in FIG. 4a and 4b and as described below with respect to the foregoing drawings.

Predvideno je sredstvo, s katerim uporabnik lahko vrti označevalno (indeksirno) kolo in krovno kolo po korakih vnaprej opredeljene velikosti. To sredstvo obsega enosmerno koračno kolo 22 in zobnik 23, ki sta medsebojno zvezana za vrtenje skupaj z označevalnim kolesom 16, vzvod 24, ki je razporejen za vrtenje okoli iste osi kot koračno kolo 22 in zobnik 23, toda neodvisno od njiju, in zobnik 25, ki ubira z zobnikom 23 in je razporejen za vrtenje krovnega kolesa 14. Vzvod 24 nosi potiskalno roko 26, katere konec je razporejen za sodelovanje z zobmi koračnega kolesa 22. Zobje koračnega kolesa so tudi v uprijemu s klinom 27, kije trdno pritrjen na telo 10. Iz razlogov, ki bodo postali očitni iz spodnjega opisa delovanja tega izvedbenega primera, zobnik 25 ni direktno priključen k krovnemu kolesu 14, marveč je priključen preko zdrsne sklopke 50, ki je spravljena v krovno kolo 14. Rezultat vgraditve te sklopke je, da pride med krovnim kolesom in zobnikom 25 do zdrsa, ko sila, potrebna za vrtenje krovnega kolesa, prekorači vnaprej določeno vrednost.Provided is a means by which the user can rotate the marking (indexing) wheel and deck wheel in steps of a predetermined size. This means comprises a unidirectional stepper wheel 22 and a gear 23 interconnected for rotation together with a marking wheel 16, a lever 24 arranged to rotate about the same axis as the stepping wheel 22 and the gear 23, but independently of them, and the gear 25 , which engages the pinion 23 and is arranged to rotate the wheel 14. The lever 24 bears a pusher arm 26 whose end is arranged to engage the teeth of the stepper wheel 22. The teeth of the stepper wheel are also in contact with the wedge 27, which is firmly attached to the body. 10. For reasons that will become apparent from the description of the operation of this embodiment below, the sprocket 25 is not directly connected to the deck 14, but is connected via a sliding clutch 50 to the wheel 14. The result of mounting this clutch is that there is a slip between the deck wheel and the sprocket 25 when the force required to rotate the deck exceeds a predetermined value.

Sklopka 50 obsega kolut 51, ki je opremljen z radialno potekajočimi zobci 52 ali s kako drugo obliko narebričenja površine, pri čemer je kolut 51 s pomočjo tlačne vzmeti 54 v uprijemu s podobno nazobčano ali narebričeno površino 53, pripravljeno na čelni ploskvi krovnega kolesa 14. Vzmet 54 se na enem koncu opira na noter usmerjeno površino 55 krovnega kolesa, na drugem pa na matico 56, ki je privita na vijak 57.The clutch 50 comprises a disc 51 which is provided with radially extending teeth 52 or some other form of ribbing, wherein the disc 51, in contact with a similarly sprung or ribbed surface 53, is provided on the front face of the deck 14. The spring 54 rests at one end on the inwardly facing surface 55 of the deck wheel and at the other on the nut 56, which is screwed onto the screw 57.

Zgoraj opisana naprava je lahko narejena tako, da jo ponovno uporabimo, ko smo porabili vse doze zdravila, vsebovane v žepkih 2. V tem slučaju se da predvideti možnost, da uporabnik pride do notranjosti naprave, naprimer z odstranitvijo pokrova 30, tako da lahko vloži nov trak 1, denimo v primerno kaseto. Alternativno pa je naprava lahko taka, da jo zavržemo, ko smo trak 1, s katerim je ona opremljena, porabili.The device described above can be made to be reused after having consumed all the doses of the drug contained in the pockets 2. In this case, it can be envisaged that the user can reach the inside of the device, for example by removing the lid 30 so that he or she can insert new tape 1, for example, into a suitable cassette. Alternatively, the device may be such that it is discarded when the tape 1 to which it is provided has been used up.

V vsakem slučaju je naprava, ko jo prvič rabimo, opremljena v komori 11 z zalogo traku 1 v obliki sorazmerno stisnjenega zvitka pod silo listne vzmeti 28, s tem da kratek del njegovega čelnega konca štrli ven iz komore 11 skozi prehod 31 k označevalnemu kolesu 16. Skrajno prednji del vodilnega konca traku je luščilno razdvojen, tako da vodilni konec krovne folije 4 lahko pritrdimo na krovno kolo 14 in da vodilni konec osnovne folije 3 lahko vstopi v prehod 33. Konec krovne folije 4 je držan na odrejenem mestu na krovnem kolesu 14 s pomočjo ključa 34, ki je silosklepno držan v reži 35 v kolesu 14.In each case, the device, when first used, is provided in the chamber 11 with a stock of tape 1 in the form of a relatively compressed roll under the force of the leaf spring 28, with a short portion of its front end projecting out of the chamber 11 through the passage 31 to the marking wheel 16 The front end of the guide end of the strap is peeled apart so that the guide end of the cover film 4 can be secured to the cover wheel 14 and that the guide end of the base sheet 3 can enter the passage 33. The end of cover sheet 4 is held in a slotted position on the cover wheel 14. by means of a key 34, which is locked in a slot 35 in the wheel 14.

Uporabnik, ki hoče uporabiti napravo, potisne vzvod 24 v protiurni smeri, gledano po skici sl. 1, tako da potisna roka 26 koračno kolo 22 potisne za kot, ki je enak kotni razdalji med sosednima zobema. To povzroči zasuk koračnega kolesa 16 za kotno vrednost, ki je enaka koraku njegovih utorov 17 in s tem enaka razdalji med sosednima žepkoma 2 v traku 1. To privede žepek 2 nasproti reži 18 v telesu 10. Ker se koračno kolo 22 in zobnik 23 gibljeta skupaj in ker zobnik 25 ubira z zobnikom 23, gibanje vzvoda 24 povzroči tudi vrtenje krovnega kolesa 14. Pri tem se zadosti dolg del krovne folije 4 odlušči od osnovne folije 3, da se razgali vsebina žepka 2, ki je prispel v poravnanost z režo 18.The user who wants to use the device pushes the lever 24 in the opposite direction, as shown in FIG. 1, such that the thrust arm 26 pushes the stepping wheel 22 an angle equal to the angular distance between adjacent teeth. This causes the stepper wheel 16 to rotate to an angular value equal to the step of its grooves 17 and thus equal to the distance between adjacent pockets 2 in the strip 1. This leads the pocket 2 towards the slot 18 in the body 10. As the stepper wheel 22 and the sprocket 23 move together and since the sprocket 25 engages the sprocket 23, the movement of the lever 24 also causes the wheel 14 to rotate 14. .

Ko uporabnik vdihava skozi ustnični kos 20, tok zraka, ki pri tem nastane, potegne s seboj prašek iz odprtega žepka, tako da uporabnik prašek vdihne. Eden od načinov, po katerem se to lahko zgodi, je bolj podrobno opisan spodaj v zvezi z izvedbenim primerom ustničnega kosa, ki ga kažeta skici sl. 4a in 4b. Vsakokrat, ko ponavljamo zgornjo proceduro, navijemo nadaljnjo dolžino krovne folije okoli krovnega kolesa 14 in nadaljnja dolžina osnovne folije vstopi v komoro 12 skozi prehod 33. Listna vzmet 29 tam notri zagotavlja, da se osnovna folija zvija in ne da bi se zatikala ob steni komore 12.As the user inhales through the lip piece 20, the resulting air stream pulls the powder out of the open pocket so that the user inhales the powder. One of the ways in which this can occur is described in more detail below with respect to the embodiment of the lip, shown in the drawings of FIG. 4a and 4b. Each time the above procedure is repeated, the further length of the cover film is wound around the cover wheel 14 and the further length of the base foil enters the chamber 12 through passage 33. The leaf spring 29 there ensures that the base foil curls without pinching against the wall of the chamber 12.

Eden od učinkov navijanja krovne folije na krovno kolo 14 je, da zunanji premer kolesa plus folije, navite nanj, postopoma raste. Če ne bi uporabili zdrsne sklopke za zvezo zobnika 25 s krovnim kolesom 14, bi zaporedne operacije vzvoda 24 stremele za tem, da bi se na krovno kolo navijala čedalje večja dolžina krovne folije. Zdrsna sklopka 50 pa odpravlja ta pojav, saj sklopka zdrsne vsakokrat za toliko, kot je treba, da je zagotovljeno, da pri vsaki operaciji vzvoda 24 dolžina krovne folije, ki se navije, ostaja natanko enaka delitvi žepkov 2.One of the effects of winding the roof foil on the roof wheel 14 is that the outer diameter of the wheel plus the foils wound on it gradually grows. Without the use of a slip clutch to engage the pinion 25 with the deck wheel 14, successive lever operations 24 would seek to wind an increasing length of deck sheet on the deck wheel. Sliding clutch 50, however, eliminates this phenomenon, since the clutch slides each time as much as is necessary to ensure that, for each lever operation 24, the length of the coiled winding sheet remains exactly the same as the split pocket 2.

Skici sl. 4a in 4b kažeta del označevalnega kolesa 16 z žepkom 2 v njem v poravnanosti z ustničnim kosom, ki se malenkostno razlikuje od ustničnega kosa 20, prikazanega v skicah sl. 1 do 3, in ki je kot celota označen s sklicevalno številko 120. Ustnični kos 120 ima zračna vstopa 140, o katerih smo na splošno že govorili v zvezi s skicami sl. 1 do 3, in osrednji izhod 119 za prašek, katerega en konec je odprt proti žepku 2, drugi konec pa se odpira v notranjost ustničnega kosa 120.Sketches fig. 4a and 4b show a portion of the marking wheel 16 with a pocket 2 therein in alignment with a lip piece slightly different from the lip piece 20 shown in the drawings of FIG. 1 to 3, and which as a whole is designated by reference numeral 120. The mouthpiece 120 has air inlets 140, which have generally been discussed in connection with the drawings of FIGS. 1 to 3, and a central powder outlet 119, one end open to the pocket 2 and the other end opening to the inside of the lip 120.

Ko uporabnik vdihava skozi ustnični kos 120, to povzroči vtekanje zraka skozi vstopa 140 in zato skozi žepek 2 v izhod 119 za prašek ter ven skozi ustnični kos 120. S takim usmerjanjem toka zraka skozi žepek 2 se doseže učinkovita vključitev praška v zračni tok, posledica česar je spraznitev žepka. Ustnični kos 120 je opremljen z dodatnimi zračnimi vstopi 121, ki so tu kot primer štirje in se odpirajo tangencialno v ustnični kos. Ko uporabnik vdihava, se zrak uvlači v ustnični kos ne le skozi zračna vstopa 140, temveč tudi skozi zračne vstope 121, in zrak, ki vstopa skozi vstope 121, povzroča vrtinčenje zračnega toka, ki pomaga porazdeliti prašek primerno po vsem zračnem toku in zmanjšati razsežnost, do katere se prašek naloži na notranji strani ustničnega kosa. To tudi pripomore k razbijanju morebitnih sprimkov praška, če se le-ti najdejo v mehurju.When the user inhales through the lip 120, this causes air to flow through inlets 140 and therefore through the pocket 2 into the powder outlet 119 and out through the lip 120. Such directing of the air flow through the pocket 2 results in effective incorporation of the powder into the air stream, resulting in which is to empty the pocket. The mouthpiece 120 is provided with additional air inlets 121, which are four as an example, and which open tangentially to the mouthpiece. As the user inhales, the air enters the lip not only through the air inlets 140 but also through the air intakes 121, and the air entering through the entrances 121 causes a swirling airflow that helps distribute the powder appropriately throughout the air stream and reduce the dimension , to which the powder is loaded on the inside of the lip piece. This also helps to break down any spills of the powder if they are found in the bladder.

Alternativna ureditev sklopke je predstavljena na skicah sl. 25 do 29. Pri njej imata označevalno kolo 16 in krovno kolo 14 zadevni ozobljeni kolesi 63 in 64, ki sta pritrjeni k njima za vrtenje skupaj z njima. Smer vrtenja je nakazana s puščicama v skici sl. 27.An alternative arrangement of the clutch is presented in the drawings of FIG. 25 to 29. The marking wheel 16 and the deck wheel 14 have the respective gear wheels 63 and 64 attached to them for rotation together with them. The direction of rotation is indicated by the arrows in the sketch of FIG. 27.

Zobnik 63 ima ozobljeno površino 65, pri čemer so zobje razporejeni kontinuirno okoli vse površine 65 in s stalno delitvijo. Temu nasprotno ima zobnik 64 ozobljeno površino 66, na kateri nekaj zob manjka z namenom izdelave radialno potekajočih rež 67. Obodna širina vsake reže na površini 66 je enaka delitvi zob. Skice kažejo tri take reže, razume pa se, da je možno shajati z eno samo, z dvema ali imeti več kot tri reže. V eno stran vsake od rež 67, v danem primeru nagornje od vsake reže glede na smer vrtenja zobnika 64, je med režo 67 in ozko špranjo 69 določen ozobljen odsek 68. Radialno notranji konec vsake špranje 69 sodeluje z odprtino 70, tako da je vsak ozobljeni del 68 priključen k preostanku zobnika 64 samo preko roke 71. Zobnik 64 ali vsaj tisti njegovi deli, ki tvorijo roke 71, so narejeni iz gradiva, ki dopušča, da se ozobljeni odseki 68 upognejo prožno nazaj in naprej v obodni smeri. Položaj mirovanja odsekov 68 je tak, kot je narisan na skicah, toda ko se na odseku 68 v smeri vrtenja zobnika 64 pojavi sila, se odsek 68 lahko premakne, tako da se reža 67 na radialno zunanjem koncu zapre. Rezultat tega je, da zob tedaj manjka ne na koncu reže 67, temveč na koncu špranje 69.The sprocket 63 has a toothed surface 65, the teeth being arranged continuously around the entire surface 65 and with constant division. In contrast, the gear 64 has a toothed surface 66, on which some teeth are missing in order to produce radially extending slots 67. The circumferential width of each slot on the surface 66 is equal to the division of the teeth. The drawings show three such slots, but it is understood that one can go with one, two or have more than three slots. To one side of each of the slots 67, preferably upwards of each slot according to the direction of rotation of the gear 64, a toothed section 68 is defined between the slot 67 and the narrow slot 69. The radially inner end of each slot 69 cooperates with an opening 70 such that each the toothed portion 68 is connected to the remainder of the sprocket 64 only through the arm 71. The sprocket 64, or at least parts thereof forming the arms 71, are made of material that allows the toothed sections 68 to bend flexibly back and forth in the circumferential direction. The resting position of the sections 68 is as shown in the drawings, but when a force is exerted on the section 68 in the direction of rotation of the pinion 64, the section 68 can be moved so that the slot 67 at the radially outer end closes. The result is that the tooth is then missing not at the end of slot 67 but at the end of slot 69.

Če je obodna sila, ki jo vnaša zobnik 63 na zobnik 64, pod vnaprej določeno vrednostjo, ozobljeni deli 68 ostanejo na svojih mestih mirovanja in zobnik 64 se vede, kot da bi imel kontinuirno ozobljeno površino, podobno tisti od zobnika 63. Če pa obtežba prekorači vnaprej določeno vrednost, se vsakokrat, ko ozobljeni odsek 68 ubira z zobnikom 63, ozobljeni odsek obodno premakne in zapre režo 67 na njenem zunanjem koncu ter odpre špranjo 69. Rezultat tega premika ozobljenega odseka 68 za razdaljo, ki je enaka delitvi zob, je zdrs zobnika 64 glede na zobnik 69 za eno delitev zob. Na ta način je predstavljena ureditev v stanju dopustiti skupen zdrs zobnikov drugega glede drugega za najmanj razdaljo, kije enaka trikratniku delitve zob na vrtljaj, s tem pa ustrezen zdrs krovnega kolesa in označevalnega kolesa drugega glede drugega. Na dlani je, da z več ali manj kot tremi predstavljenimi ozobljenimi odseki dobimo več ali manj od tega največjega zdrsa.If the circumferential force applied by the gear 63 to the gear 64 is below a predetermined value, the gear parts 68 remain at their resting points and the gear 64 acts as if it had a continuous toothed surface similar to that of the gear 63. exceeds a predetermined value, each time the toothed section 68 engages a gear 63, the toothed section circumferentially moves and closes the slot 67 at its outer end and opens the slit 69. The result of this movement of the toothed section 68 for a distance equal to the tooth division is slip of gear 64 relative to gear 69 for one tooth division. In this way, the arrangement presented is able to allow a common slip of the gears of each other for a minimum distance equal to three times the division of the teeth per revolution, and thus a corresponding slip of the deck wheel and the marking wheel of each other. In the palm of your hand, with more or less than three of the toothed sections presented, more or less of this largest slip is obtained.

Drugi izvedbeni primer inhalacijske naprave po izumu je predstavljen v skicah sl. 5 do 9. Namen tega je uporaba skupaj s trakom 201, ki je podoben traku 1, uporabljenemu v prvem izvedbenem primeru, z izjemo kar se tiče razmika med žepki (za kar glej podrobnosti spodaj). V več pogledih drugi izvedbeni primer posnema prvega in tako so sestavine v drugem izvedbenem primeru, ki v splošnem ustrezajo istosmiselnim sestavinam prvega izvedbenega primera, označene z istimi sklicevalnimi številkami, le z dodatkom 200. Glavna razlika med prvim in drugim izvedbenim primerom je, da v slednjem ni označevalnega (indeksirnega) kolesa, ki bi ustrezal označevalnemu kolesu 16 prvega izvedbenega primera. Namesto tega pridemo do označevanja traku 1, da zagotovimo, da vsak premik vzvoda pomakne trak za vrednost, kije enaka delitvi žepkov, s tem, da uporabimo prožno podajno roko 250, ki se konča z zobom 252, ki uprijema med sosedna žepka. Vsakokrat, ko premaknemo vzvod 224, se roka 250 prožno odmakne, ko žepek drsi mimo njenega zoba 252, zatem pa zob vskoči nazaj v naleganje na trak na hrbtni strani tistega žepka, ki je pravkar šel mimo njega.Another embodiment of the inhalation device of the invention is presented in the drawings of FIG. 5 to 9. This is intended to be used in conjunction with the ribbon 201, similar to the ribbon 1 used in the first embodiment, with the exception of the pocket spacing (for details see below). In several respects, the second embodiment mimics the first, and so the ingredients in the second embodiment, which generally correspond to the same components of the first embodiment, are denoted by the same reference numbers only by the addition of 200. The main difference between the first and second embodiment is that in the latter does not have a marking wheel that matches the marking wheel 16 of the first embodiment. Instead, we mark the lane 1 to ensure that each lever displacement moves the lane by a value equal to the division of the pockets by utilizing a flexible feed arm 250 that ends with a tooth 252 that resists between adjacent pockets. Each time the lever 224 is moved, the arm 250 moves away flexibly as the pocket slides past its tooth 252, then jumps back into place on the strap on the back of the pocket that just went past it.

Na dlani je, da se, kot pri prvem izvedbenem primeru, premer krovnega kolesa 214 s krovno folijo na njem med delovanjem postopoma povečuje. Ker pri tej izvedbi ni moč uporabiti zdrsne sklopke, se pravkar opisani pojav kompenzira s tem, da se razmik žepkov 2 v smeri proti zadnjemu koncu traku postopoma povečuje.It is in the palm of your hand that, as in the first embodiment, the diameter of the deck wheel 214 with the cover sheet on it gradually increases during operation. Since the slip clutch cannot be used in this embodiment, the phenomenon just described is compensated for by the gradual increase in the spacing of the pockets 2 towards the rear end of the strap.

Nadaljnja razlika, ki jo lahko najdemo med prvo in drugo izvedbo, je, da komori 211 in 212 v slednji tvorita eno samo sestavljeno komoro v nasprotju z ločenima komorama 11 in 12 v prvi izvedbi. Vendar pa to ni nujno tako, saj prva izvedba lahko deluje z eno samo sestavljeno komoro, v drugi izvedbi pa lahko predvidimo ločeni komori.A further difference to be found between the first and second embodiments is that chambers 211 and 212 in the latter form a single compound chamber as opposed to separate chambers 11 and 12 in the first embodiment. However, this is not necessarily the case, since the first embodiment can operate with a single composite chamber, and in the second embodiment, separate chambers may be provided.

Skice sl. 10 do 12 kažejo tretji izvedbeni primer. Ta v več pogledih posnema drugi izvedbeni primer in zato so sestavine v tretjem izvedbenem primeru, ki v splošnem ustrezajo sestavinam v drugem, označene z istimi sklicevalnimi številkami, toda z dodatkom še 100.Figs. 10 to 12 show a third embodiment. In many respects, this imitates the second embodiment, and therefore the ingredients in the third embodiment, which generally correspond to the components in the second embodiment, are denoted by the same reference numbers, but with the addition of 100 more.

Ena od razlik med drugo in tretjo izvedbo, ki pade v oči, je, da je namesto krovnega kolesa 114 uporabljena dvojica koles 314a in 314b, pri čemer je krovna folija zgrabljena z uščipom med kolesoma 314a in 314b, ki delujeta tako kot likalna valjarja (valjalna valja). Ti kolesi sta narebričeni ali kako drugače hrapavi, da se izboljša zgrabitev med kolesoma in krovno folijo. Uporabljena krovna folija se ne navija, temveč je vodena v komoro 313, tako da s krovnim kolesom, ki naj bi navijalo čedalje daljše dolžine krovne plasti, ki se pojavljajo med delovanjem naprave, ne pride do nikakršnega problema, kot je to slučaj pri prvih dveh izvedbenih primerih.One of the differences between the second and third embodiments that strikes the eye is that instead of the deck wheel 114, two wheels 314a and 314b are used, with the roof sheet being grabbed by a pinch between the wheels 314a and 314b, which act as irons ( rolling cylinder). These wheels are ribbed or otherwise rugged to improve the grip between the wheels and the deck sheet. The roof foil used is not bent but guided into chamber 313, so that there is no problem with the deck wheel, which is supposed to wind the ever longer lengths of the deck layer during operation of the device, as is the case with the first two implementation cases.

Skica sl. 11 kaže ustnični kos, kije nekoliko drugačen od onega s sl. 4a in 4b. Gre za ustnični kos, ki ima en sam zračni vstop 340 namesto dvojice zračnih vstopov 140, izstop 119 praška po sl. 4a in 4b pa je nadomeščen z delom 319 ustničnega kosa zmanjšane širine. Ob tem naj bi razumeli, da napravo, prikazano v skicah sl. 10 do 12, lahko modificiramo, tako da ustnični kos vgradimo bolj podobno izvedbi po sl. 4a in 4b.Sketch of FIG. 11 shows an oral piece slightly different from the one in FIG. 4a and 4b. It is a lip piece having a single air inlet 340 instead of a pair of air inlets 140, the outlet 119 of the powder according to FIG. 4a and 4b, however, is replaced by a reduced width portion 319 of the lip. It should be understood that the apparatus shown in the drawings of FIG. 10 to 12 can be modified to fit the lip piece more like the embodiment of FIG. 4a and 4b.

Sl. 10 kaže napravo, ki je opremljena s šarnirsko obešenim pokrovom 360, kakršnega lahko predvidimo za katero koli od prvih dveh izvedb. Sl. 12 kaže napravo, ki ima okence 370, skozi katero lahko vidimo oznake na traku. Če je trak potiskan s številkami ali drugimi oznakami, ki se nanašajo na število žepkov, iz katerih smo izvlekli prašek, oziroma, alternativno, iz katerih prašek lahko odtegnemo, je uporabnik oskrbljen s podatkom o tem, koliko doz je porabljenih oziroma, alternativno, koliko jih je še na voljo. Druga možnost je, da uporabimo napravo za štetje doz, ki jo poganja ena od vrtilnih sestavin inhalacijakse naprave. Razume se, da podobne oznake in sredstva za gledanje le-teh lahko predvidimo prav v vseh izvedbenih primerih.FIG. 10 shows a device provided with a hinged hinge 360, such as can be provided for any of the first two embodiments. FIG. 12 shows a device having a window 370 through which the marks on the strap can be seen. If the tape is printed with numbers or other marks referring to the number of pockets from which the powder was extracted, or, alternatively, from which the powder can be withdrawn, the user is provided with information on how many doses have been consumed or, alternatively, how much they are still available. Alternatively, we can use a dose counting device driven by one of the rotational components of the inhalation device. It is understood that similar markings and means of viewing them may be provided in all embodiments.

Skice sl. 13 do 16 kažejo nadaljnji izvedbeni primer izuma. Ta je po bistvu svojega delovanja podoben prvemu izvedbenemu primeru in sestavine v četrtem izvedbenem primeru, ki na splošno ustrezajo sestavinam v prvi izvedbi, so označene z istimi sklicevalnimi številkami, le z dodatkom 400.Figs. 13 to 16 show a further embodiment of the invention. This is similar in essence to its first embodiment, and the ingredients in the fourth embodiment, which generally correspond to the ingredients in the first embodiment, are numbered with the same reference numbers only with the addition of 400.

Kot pri prvi izvedbi naprava sprejme gibek trak, kije tu označen s številko 401, ki obsega osnovno folijo 403, v kateri so določeni žepki 402, in krovno folijo 404. Trak 401 je bolj jasno predstavljen na sl. 35. Krovna folija 404 ima zanko 404a, ki je narejena na njenem začetnem koncu in predvidena za nataknitev na stebriček 471a, ki štrli pokonci z zobnika 471 (opisan spodaj). Osnovna folija ima vodilni del 403a zmanjšane širine za vložitev v režo 470a, narejeno v kolesu 470 za navijanje osnove (opisano spodaj). Vodilna končna dela osnovne folije in krovne folije medsebojno nista zlepljena, kot lahko vidimo na sl. 35.As in the first embodiment, the device accepts a flexible strip, designated here 401, comprising a base foil 403 in which the pockets 402 are defined and a cover foil 404. The strip 401 is more clearly represented in FIG. 35. The roof foil 404 has a loop 404a, which is formed at its beginning end and is intended for attachment to a pillar 471a projecting upright from the sprocket 471 (described below). The base foil has a guide section 403a of reduced width for insertion into the slot 470a made in the wheel 470 for winding the base (described below). The leading end portions of the base foil and the cover foil are not glued to each other, as can be seen in FIG. 35.

Telo 410 obsega osnovo 410a in strop 410b, oba v splošnem okrogle oblike. Ko je naprava sestavljena, sta osnova in strop združena z zaskočnim spojem. Telo določa eno samo notranjo komoro, v katero je vložen trak 401 in v kateri se nahajajo tudi kolo 414 za navijanje porabljenega dela krovne folije 404, kolo 470 za navijanje osnove in označevalno (indeksirno) kolo 416. Označevalno kolo 416 je votlo in v njem se nahaja označevalno enosmerno koračno kolo 422. Vsa pravkar omenjena kolesa so v komoro, ki jo določa telo, vgrajena za vrtilno gibanje glede na telo. Klin 470b je priključen k telesu 410 in sodeluje z zobmi kolesa 470 za navijanje osnove, da je preprečeno vrtenje kolesa v protiurni smeri, s čimer je zagotovljeno, da trak 401 skozi napravo lahko samo napreduje.The body 410 comprises a base 410a and a ceiling 410b, both generally round in shape. When assembled, the base and ceiling are joined by a snap joint. The body defines a single inner chamber into which the strip 401 is inserted, which also includes a wheel 414 for winding the spent portion of the roof foil 404, a wheel 470 for winding the base and a marking (indexing) wheel 416. The marking wheel 416 is hollow and therein there is a one-way stepper wheel 422. All the wheels just mentioned are housed in a body-defined chamber for rotational motion relative to the body. The wedge 470b is connected to the body 410 and cooperates with the teeth of the wheel 470 to wind the base to prevent the wheel from rotating in the counter-direction, ensuring that the belt 401 can progress through the device only.

Kolo 414 za navijanje krovne folije je dvodelno in obsega zobnik 471, ki ima zobe 472 in os 473, in snemljivo kolo 474, ki ima votlo osrednjo os 475 in več, naprimer osem, kot je narisano, prožnih rok 476, štrlečih z osrednje osi 475 vsaka pod določenim kotom glede na polmer. Zobnik 471 ima nastavek 477, ki sodeluje s prirejenim izrezom v osi 475, tako da se kolesi 471 in 474 vrtita skupaj.The roof foil winding wheel 414 is two-piece and comprises a gear 471 having teeth 472 and an axis 473, and a detachable wheel 474 having a hollow central axis 475 and above, for example eight, as shown, of flexible arms 476 projecting from the central axis 475 each at a certain angle with respect to radius. Gear 471 has a nozzle 477 that cooperates with the adapted cutout in the axis 475 so that the wheels 471 and 474 rotate together.

Votlo označevalno kolo 416 ima zunanje zobe 478, ki ubirajo z zobmi kolesa 470 za navijanje osnovne folije in zobmi kolesa 471. Preskakovalni zobje 479 so oblikovani na notranjih stenah označevalnega kolesa 416, označevalno koračno kolo 422 pa ima dva klina 480, ki sodelujeta s preskakovalnimi zobmi 479.The hollow marking wheel 416 has outer teeth 478 that engage with the teeth of the wheel 470 for winding the base film and the teeth of the wheel 471. The jumping teeth 479 are formed on the inner walls of the marking wheel 416, and the marking stepping wheel 422 has two wedges 480 cooperating with the skip teeth 479.

Naprava nadalje obsega vzvod 424, ki vsebuje ločno steno 481 s pritisnim nastavkom 482 za prst, in roko 483, ki sega noter s stene 481 in na svojem od vpetišča oddaljenem (distalnem) koncu nosi ločni niz zob 484. Vzvod je zasučno pritrjen v sredo osnove 410a za gibanje okoli osi, ki je na sredi delilnega kroga zob 484, pri čemer zobje 484 ubirajo z zobmi 458 na označevalnem koračnem kolesu 422.The device further comprises a lever 424 comprising a detached wall 481 with a finger attachment 482 and an arm 483 extending inwardly from the wall 481 and carrying a separate set of teeth at its distal end 484. The lever is pivotally mounted on Wednesday a base 410a for movement about an axis which is in the middle of the dividing circle of the teeth 484, the teeth 484 being harvested by the teeth 458 on the marking stepper wheel 422.

Zvezo med komoro v telesu 410 in ustničnim kosom 420 vzpostavlja razdelilnik 486. Ta ima izpust 419 za prašek, ima pa tudi prehod 487, po katerem uporabljeni krovni trak 404 lahko poteka k snemljivemu kolesu 474. Po želji lahko predvidimo valjček 488 za vodenje traku 404 v prehod 487.The connection between the chamber in the body 410 and the lip 420 is established by the distributor 486. This has a discharge 419 for the powder, and also has a passage 487, through which the used belt 404 can go to the detachable wheel 474. If desired, a roller 488 can be provided to guide the tape 404 into passage 487.

Obroč 489 za nadzorovanje doz, ki ima zobe 490, je razporejen tako, da je vrtljiv v osnovi 410a telesa naprave. Na svoji spodnji površini ta nosi oznake (niso vidne na skicah), ki jih uporabnik lahko vidi skozi okence 494 v telesu 410. S skic sl. 16a do 16d (brez č) se vidi, da okence lahko vidimo tako tedaj, koje pokrov 491 (glej spodaj) zaprt, kot tudi tedaj, ko je le-ta odprt. Oznake kažejo bodisi natančno aliepribližno število doz, ki so še ostale (ali število uporabljenih doz, če ja ta podatek pomembnejši). Obroč 489 se vrti na osnovi tega, da njegovi zobje 490 sodelujejo z zobmi 478 označevalnega kolesa.The dose control ring 489 having teeth 490 is arranged such that it rotates at the base 410a of the body of the device. On its lower surface it bears markings (not visible in the drawings) which the user can see through the window 494 in the body 410. From the drawings of FIG. 16a to 16d (without h), it can be seen that the window can be seen both when the lid 491 (see below) is closed as well as when it is open. The labels indicate either the exact or approximate number of doses remaining (or the number of doses used, if more relevant). Ring 489 rotates on the basis that its teeth 490 interact with the teeth 478 of the marking wheel.

Naprava je spravljena pod pokrov 491, ki je zasučno pritrjen na telo 410 s pomočjo jezika 492 na stropu 410b telesa in prirejenega jezika 493 na osnovi 410a telesa. Pokrov je zasučen med odprtim položajem (predstavljen v sl. 14), v katerem je ustnični kos izpostavljen, in zaprtim položajem, v katerem ta ni izpostavljen, kar je bolj podrobno opisano spodaj.The device is placed under cover 491, which is pivotally attached to the body 410 by the tongue 492 on the ceiling 410b of the body and the adapted tongue 493 based on the body 410a. The lid is rotated between the open position (represented in FIG. 14) in which the lip piece is exposed and the closed position in which it is not exposed, which is described in more detail below.

Pri uporabi uporabnik premakne pokrov 491 k njegovemu odprtemu položaju in nato pritisne na nastavek 482 za prst pri vzvodu 424, tako da se ta premakne, ko se vzvod zasuka. To privede do zasuka označevalnega koračnega kolesa 422, ki preko klinov 480 povzroči zasuk tudi označevalnega kolesa 416. Vrtenje označevalnega kolesa 416 pomeni vrtenje tako kolesa 470 za navijanje osnovne folije kot tudi kolesa 414 za navijanje krovne folije, s tem pa seveda luščenje osnovne folije in krovne folije druge od druge na razdalji, ki zadošča za razgaljenje pred tem neodprtega žepka 402 nasproti koncu izstopa 419 za prašek v razdelilniku 486. Bolnik lahko temu sledeče vdihava skozi ustnični kos kot pri predhodnih izvedbenih primerih.In use, the user moves the cover 491 to its open position and then presses the finger attachment 482 at the lever 424 so that it moves as the lever rotates. This leads to the rotation of the marking stepper wheel 422, which also causes the marking wheel 416 to rotate through the pegs 480. Rotation of the marking wheel 416 means the rotation of both the wheel 470 for winding the base film and the wheel 414 for winding the cover film, and of course the peeling of the base film and cover foils from each other at a distance sufficient to open the previously open pocket 402 toward the end of the powder outlet 419 in the dispenser 486. The patient may then inhale through the lip piece as in the previous embodiments.

Zaporedne operacije v delovanju naprave so predstavljene v skicah sl. 16a do 16d. Na sl. 16a je naprava v svojem zaprtem položaju. Nastavek 482 za prst pri vzvodu 424 je v tej fazi v vdrtini 482b, narejeni v telesu 410 (bolje se vidi na sl. 16b in 16c). Pokrov 491 je pri miru, ko se telo 410 vrti v protiumi smeri, pri čemer je na obodu telesa predviden izrez 410c, v katerega uporabnik lahko v ta namen vloži svoj prst. Naprava se torej premakne v delno odprti položaj, ki ga kaže sl. 16b. Med to operacijo vzvod 424 ostane pri miru glede na pokrov 491. To je doseženo s tem, da je vzvod opremljen znotraj s prožno roko 424a, katere vrh 424b sodeluje z izrezom 491a v pokrovu 491. Roka 424a je k vzvodu 424 priključena preko cilindričnega dela 424c. Kot se vidi s skice sl. 16a, sega roka 424a v protiurnem smislu od dela 424c na loku okoli 90°. Cilindrični del 424c je voden v ločni reži 410d, narejeni v telesu 410. Reža 410d poteka v loku dolžine okoli 180°, na skici sl. 16a pa je predstavljen del 424c, ko se nahaja nekako na polovici dolžine reže. Na sl. 16b je taisti narisan na koncu reže.Successive operations in the operation of the device are presented in the drawings of FIG. 16a to 16d. In FIG. 16a is the device in its closed position. The finger attachment 482 at the lever 424 is at this stage in a recess 482b formed in the body 410 (better seen in FIGS. 16b and 16c). Cover 491 is at rest when the body 410 rotates in the opposite direction, with a recess 410c provided at the periphery of the body into which the user can insert his or her finger for this purpose. The device therefore moves to the partially open position shown in FIG. 16b. During this operation, the lever 424 remains at rest with respect to cover 491. This is achieved by the lever being provided internally with a flexible arm 424a, the tip of which 424b interacts with the cutout 491a in cover 491. The arm 424a is connected to the lever 424 via a cylindrical part 424c. As can be seen from the drawing of FIG. 16a, extends arm 424a in a counter-direction from portion 424c at an arc of about 90 °. The cylindrical portion 424c is guided in a separate slot 410d formed in the body 410. The slot 410d runs in an arc about 180 ° long, in the sketch of FIG. 16a, however, is shown a portion 424c when located about halfway down the slot. In FIG. 16b is the one drawn at the end of the slot.

Uporabnik še naprej vrti telo 410 s položaja po sl. 16b v položaj, ki ga kaže sl. 16c. Pri tem nadaljnjem vrtenju vrh 424b roke 424a izskoči iz izreza 491a. Do tega pride, ker v stanju, ko je del 424c na enem koncu reže 410d, gibanje telesa 410 vleče del 424c s seboj v protiurni smeri in zato sili roko 424a prav tako v protiurno gibanje. Uporabnik zatem premakne vzvod 424 s pritiskom na nastavek 482 za prst in ga zavrti v protiurni smeri preko položaja, ki ga kaže skica sl. 16c, do položaja, kije predstavljen na sl. 16d, ko nastavek 482 za prst ponovno vstopi v izrez 482b. Koraki, ki smo jih na ta način pobliže opisali, privedejo tako do tega, da se ustnični kos 420 razgali, kot tudi do tega, da se odpre sveži mehurček. Naprava je zato tedaj pripravljena, da uporabnik lahko vdihava.The user continues to rotate the body 410 from the position of FIG. 16b to the position shown in FIG. 16c. In this further rotation, the tip 424b of arm 424a pops out of the cutout 491a. This occurs because in the state when the portion 424c is at one end of the slot 410d, the movement of the body 410 pulls the portion 424c with it in an anticlockwise direction and therefore forces the arm 424a also in an anticlockwise motion. The user then moves the lever 424 by pushing the finger attachment 482 and rotating it counter-clockwise beyond the position shown in FIG. 16c to the position represented in FIG. 16d when the finger insert 482 re-enters the recess 482b. The steps described in this way result in both the mouthpiece 420 being blown apart and the fresh bubble opening. The device is then ready for the user to breathe.

Po uporabi telo 410 zavrtimo v urni smeri, pri čemer se vzvod 424 premika hkrati s telesom, tako da naprava preide nazaj v položaj po sl. 16a.After use, the body 410 is rotated clockwise, with the lever 424 moving simultaneously with the body so that the device moves back to the position of FIG. 16a.

Na dlani je, da snemljivo kolo 474 pravzaprav prevzame vlogo sklopke iz prvega izvedbenega primera. Z naraščanjem količine krovne folije, navite na kolo 474, se roke 476 postopoma podajajo noter, rezultat tega pa je, daje zunanji premer zvitka navite krovne folije v bistvu konstanten, medtem ko se notranji premer le-tega postopoma manjša.In the palm of your hand, the detachable wheel 474 actually acts as a clutch from the first embodiment. As the amount of roof foil wound onto the wheel 474 increases, the arms 476 gradually extend inwards, resulting in the outer diameter of the roll of the wound foil being substantially constant, while the inside diameter of the roof film gradually decreases.

Namesto kolesa 414 s pripadajočim snemljivim kolesom 474 je možno uporabiti alternativno zgradbo, ki jo kaže skica sl. 30, ali tisto, ki jo kažeta skici sl. 31 in 3la. Princip vrtenja zgradbe, predstavljene na sl. 30, je zelo podoben tisti pri ureditvi sklopke, ki jo kažejo skice sl. 25 do 29. Zgradba s sl. 30 obsega dve sestavini 800 in 801. Sestavina 800 obsega v splošnem valjasto votlo ohišje 802, ki je odprto na svojem spodnjem koncu, in tri ločne nize zob 803. Valj 802 ima režo 804, ki poteka skozi njegovo zgornjo površino, in stebriček 805 za sprejem vodilnega konca krovne folije. Sestavina 801 obsega ploščo 806, ki ima tri ločne nize zob 807, in pokončen del 808, ki poteka gor od plošče 806. Del 808 je narejen iz gradiva, naprimer iz plastike, ki je prožno pri zvijanju.Instead of wheel 414 with associated detachable wheel 474, an alternative structure shown in FIG. 30, or the one shown in FIGS. 31 and 3la. The principle of rotation of the building presented in Figs. 30 is very similar to the arrangement of the coupling shown in the drawings of FIG. 25 through 29. The building of FIG. 30 comprises two components 800 and 801. The component 800 comprises generally a cylindrical hollow housing 802 open at its lower end and three separate sets of teeth 803. The cylinder 802 has a slot 804 extending through its upper surface and a column 805 for receiving the leading end of the roof foil. The component 801 comprises a plate 806 having three separate sets of teeth 807 and an upright portion 808 extending up from the plate 806. The portion 808 is made of material, such as plastic, which is flexible when twisted.

Dela 800 in 801 sta drug z drugim zaskočno spojena, tako da zgornji konec dela 808 vstopi v režo 804 in se glede na slednjo ne more zavrteti. Nizi zob 803 in 807 so enoravninski (koplanarni) in se medsebojno menjajo (alternirajo): nizu enega dela sledi niz drugega. Zobje 803 in 807 ubirajo z zobmi 478 označevalnega kolesa. Vsak niz 807 je od enega od sosednih nizov 803 (ne pa tudi od drugega) ločen z vrzeljo, ki je enaka enemu zobu. Tako imamo okoli združenih nizov tri vrzeli širine vsakokrat za en zob. Ker se del 808 lahko torzijsko zvije, je plošča 806 prosto gibljiva nazaj in naprej med položajem, ko so vrzeli vse na eni strani zadevnega niza 807, in položajem, v katerem so vrzeli vse na drugi strani zadevnega niza 807. Posledica tega je ustvarjanje zdrsa zgradbe, ki jo kaže sl. 30, glede na označevalno kolo.Parts 800 and 801 are locked together so that the upper end of portion 808 enters the slot 804 and cannot rotate relative to the latter. The sets of teeth 803 and 807 are one-plane (coplanar) and alternate (alternate): the set of one part is followed by the set of the other. Teeth 803 and 807 are harvested by the teeth of the marking wheel 478. Each set 807 is separated from one of the adjacent sets 803 (but not the other) by a gap equal to one tooth. So we have three width gaps around one group of teeth each time per tooth. Because the part 808 can be torsionally twisted, the plate 806 is free to move back and forth between the position where the gaps are all on one side of the respective set 807 and the position in which the gaps are all on the other side of the set 807. This results in a slip of the building shown in FIG. 30, according to the marking wheel.

Zgradba, ki jo kaže sl. 31, je zdrsna sklopka. Ta obsega dve sestavini 810 in 811, ki sta združeni s pomočjo zaskočnega ujema. Sestavina 810 obsega v splošnem valjasto ohišje 812, ki je na svojem spodnjem koncu odprto in ima steber 813 za sprejem vodilnega konca krovne folije. Notranjost ohišja 812 je opremljena z vzdolžno potekajočimi rebri 814, kot se vidi s skice sl. 31a. Sestavina 811 obsega valj 815, ki poteka gor od plošče 816, ki je opremljena z zobmi 817. Zobje 817 ubirajo z zobmi 478 označevalnega kolesa. Valj 815 je na svoji zunanji površini opremljen z dvojico ostrorobih štrlin 818, ki ubirno sodelujeta z rebri 814. Če je vrtilna sila, ki jo na sestavino 810 vnaša sestavina 811, pod vnaprej določeno vrednostjo, se sestavini vrtita skupaj. Toda valj je narejen iz gradiva, naprimer plastičnega, ki se radialno lahko deformira, in ko vrtilna sila preseže vnaprej določeno vrednost, pride do take deformacije, rezultat česar je premik štrlin 818 preko reber 814.The structure shown in FIG. 31, is a slip clutch. This comprises two components 810 and 811, which are joined by a snap-lock. The assembly 810 comprises generally a cylindrical housing 812 which is open at its lower end and has a pillar 813 for receiving the guide end of the cover sheet. The interior of the housing 812 is provided with longitudinally extending ribs 814, as seen from the sketch of FIG. 31a. The assembly 811 comprises a cylinder 815 extending up from the plate 816, which is provided with teeth 817. The teeth 817 are engaging with the teeth 478 of the marking wheel. The roll 815 is provided on its outer surface with a pair of sharpened projections 818 that cooperatively cooperate with the ribs 814. If the rotational force exerted on the component 810 by the component 811 is below a predetermined value, the components rotate together. However, the cylinder is made of material, such as plastic, which can be radially deformable, and when the rotational force exceeds a predetermined value, such deformation occurs, resulting in the displacement of projections 818 over ribs 814.

Čeprav je v izvedbenem primeru po skicah sl. 13 do 16 z modifikacijama po sl. 30 in 31 ali brez njiju osnovna folija kot tudi krovna folija navita, pa ni potrebe, da bi med označevalnim kolesom in kolesom za navijanje osnove obstajala zdrsna sklopka ali podobno. Premer kolesa za navijanje osnove je tako izbran, da je spočetka osnovna folija navita le zelo ohlapno, nakar zategnjenost, s katero je folija navita, med delovanjem narašča, ne da bi kadar koli dosegli nesprejemljivo vrednost. Po teoriji se da osnovno folijo navijati natančno preko zdrsne sklopke ali podobnega, pri čemer se krovna folija navija le ohlapno, ampak v praksi je mnogo enostavneje, da natančno navijemo krovno folijo, ker je ta ravna (ploska) in ker je tanjša od osnovne folije.Although in the embodiment, according to the drawings of FIG. 13 through 16 with the modifications of FIG. 30 and 31, or without the base foil as well as the cover foil, there is no need for a slip clutch or the like between the marking wheel and the warp wheel. The diameter of the warp wheel is so chosen that at first the base film is wound very loosely, and then the tension with which the film is wound increases during operation without reaching an unacceptable value at any time. In theory, the base foil can be wound exactly through a slip clutch or the like, with the roof foil only loosened, but in practice, it is much easier to wind the roof foil precisely because it is flat (flat) and thinner than the base foil. .

Skice sl. 17 do 20 kažejo v ponazoritveni obliki glavne funkcijske dele naprave, ki ima nekaj podobnosti s tisto s skic sl. 10 do 12, t.j., gre za valjalno napravo. Razumeti pa moramo, da skice sl. 17 do 20 ne kažejo popolne naprave, kajti komora za neuporabljeni trak in material porabljene osnove sta opuščena. Sestavine v tej izvedbi, ki na splošno ustrezajo vsakokratnim sestavinam v izvedbenem primeru po sl. 10 do 12, so označene z istimi sklicevalnimi številkami, toda povečanimi za nadaljnjih 200.Figs. 17 to 20 show, in illustrative form, the principal functional parts of the apparatus, which bears some resemblance to that of FIGS. 10 to 12, i.e., it is a rolling device. However, it should be understood that the sketches of FIG. 17 to 20 do not show a complete device, as the unused tape chamber and the base material consumed are abandoned. The ingredients in this embodiment which generally correspond to the respective ingredients in the embodiment of FIG. 10 to 12 are indicated by the same reference numbers, but increased by a further 200.

Naprava po sl. 17 do 20 obsega dvojico koles 514a in 514b, ki imata na sebi oblikovane ubirajoče zobe in ki delujeta kot valjalna naprava, ki sprejme uporabljeni krovni material. Ta material se vodi v komoro 513. Kolo 514b je prosto kolo in ga v uprijem s kolesom 514a tišči tlačna vzmet 595, ki deluje na nosilec 596, ki nosi kolo 514b. Kolo 514a ima obroč zobniških zob 598, ki ubirajo z zobmi 597, predvidenimi na označevalnem kolesu 516, ki izvaja isto označevalno funkcijo kot označevalno kolo 16 v prvem izvedbenem primeru in je vrtljivo v komori 515. Komori sta narejeni v telesu 510 in k nasprotnima stranema komore sta pritrjena pokrova 530a in 530b. Vdihava se skozi ustnični kos 520. Naprava se upravlja s pomočjo vzvoda 524, ki preko potisne roke 526 obrača označevalno kolo 516.The apparatus of FIG. 17 to 20 comprise a pair of wheels 514a and 514b which have molded teeth and act as a rolling device for receiving the material used. This material is guided to the chamber 513. The wheel 514b is a free wheel and is held in contact with the wheel 514a by a pressure spring 595 acting on a carrier 596 carrying the wheel 514b. The wheel 514a has a ring of gear teeth 598 which engage with the teeth 597 provided on the marking wheel 516, which performs the same marking function as the marking wheel 16 in the first embodiment and is rotatable in chamber 515. The chambers are made in body 510 and opposite sides. chambers are fitted lids 530a and 530b. It is inhaled through the lip 520. The device is controlled by a lever 524 which rotates the marking wheel 516 through the pushing arm 526.

Izvedbeni primer, ki ga kažejo skice sl. 21 do 24, je nadaljnja vrsta likalne valjalne naprave, tokrat take, pri kateri tako krovna kot tudi osnovna folija potujeta skozi valjalni kolesi.The embodiment shown in the drawings of FIG. 21 to 24 is a further type of ironing rolling device, this time one in which both the base and the base foil travel through the rolling wheels.

Izvedbeni primer po sl. 21 do 24 obsega telo 610, ki določa v bistvu krožno komoro 611, h kateri sta pritrjena pokrova 612a in 612b. V komori 611 sta vrtljivo vgrajeni označevalno kolo 613 in kolo 614 za navijanje osnove in krovne folije, pri čemer imata kolesi 613 in 614 zobniške zobe, ki medsebojno ubirajo. Označevalno kolo 613 ima žlebove 615, blizu žlebov 615 pa je nadolnje od razdelilnika 616 vgrajeno kolo 618 za grabljenje krovne folije, ki je vrtljivo držano v nosilcu 619. Za razdelilnikom 616 je za vodenje krovne folije vgrajen valj 620.An embodiment of FIG. 21 to 24 comprise a body 610 defining essentially a circular chamber 611 to which the covers 612a and 612b are attached. In the chamber 611, the marking wheel 613 and the wheel 614 for winding the base and the roof foil are rotatably mounted, the wheels 613 and 614 having gear teeth which engage each other. Marker wheel 613 has grooves 615, and near the grooves 615, there is a roller catcher 618 mounted downstream of the manifold 616, which is rotatably held in the carrier 619. A roller 620 is mounted behind the manifold 616 to guide the umbrella film.

V komori 611 je predviden gibek trak 601, katerega glavni del je sprva navit okoli notranje stene komore. Vodilni konec traku potuje med vodilnima deloma 622 in 623 preko dela oboda označevalnega kolesa 613, pri čemer žepki traku, ki vsebujejo prašek, pridejo v žlebove 615. Na mestu, kjer se trak sreča z razdelilnikom 616, se trak luščilno razdvoji, krovna folija potuje za razdelilnikom in čez valj 620, medtem ko osnovna folija potuje med označevalnim kolesom in razdelilnikom. Za razdelilnikom potujeta obe foliji med označevalnim kolesom in kolesom 618 za grabljenje krovne folije, ki ju držita v prijemu. Prednji konec traku je fiksiran v kolesu 614 za navijanje osnove in krovne folije.In the chamber 611 is provided a flexible strip 601, the main part of which is initially wound around the inner wall of the chamber. The guide end of the strip travels between guide portions 622 and 623 through the portion of the circumference of the marking wheel 613, with the pockets of the tape containing the powder coming into the grooves 615. At the point where the strip meets the distributor 616, the strip is peeled off, the cover film travels behind the manifold and over the roller 620 while the base film travels between the marking wheel and the manifold. Behind the manifold, both films travel between the marking wheel and the pickup roller wheel 618, which hold them in the grip. The front end of the strap is fixed in the wheel 614 for winding the base and the roof foil.

Med uporabo trak 601 napreduje z vrtenjem označevalnega kolesa s pomočjo vzvoda 624 preko potiskalne roke 626, ki povzroči zadevno vrtenje kolesa za navijanje osnovne in krovne folije. Le-to navija osnovno in krovno folijo sprva ohlapno, toda s čedalje večjo zategnjenostjo tekom uporabe, ne da bi zategnjenost kadar koli dosegla nesprejemljivo vrednost. Krovna in osnovna folija se druga od druge luščita tam, kjer se trak sreča z razdelilnikom 616, tako da se pred izstopom 617 za prašek pojavi svež žepek s praškom. Vdihava se preko ustničnega kosa 620.During use, the strip 601 advances the rotation of the marking wheel by means of a lever 624 through the pusher arm 626, which causes the respective rotation of the wheel for winding the base and cover films. It first loosens the base and cover sheets at first, but with increasing tightness during use, without tightening at any time to an unacceptable value. The cover and base foil are peeled off from each other where the strip meets the dispenser 616, so that a fresh powder pocket appears before exiting 617 for the powder. It is inhaled via the mouthpiece 620.

Skice sl. 32 do 34 kažejo izvedbo izuma, pri kateri gre kot za nadaljnjo značilnost za označitve, ki uporabnika usmerjajo na sledeče si korake, ki jih mora uporabnik opraviti z napravo. Razen teh označitev je naprava v glavnem ista kot pri izvedbi s sl. 1 do 3, tako da so za istovrstne sestavine uporabljene iste sklicevalne številke. Gre pa za nekaj dodatnih sestavin, kot bo razvidno iz naslednjega opisa.Figs. 32 to 34 show an embodiment of the invention, which is a further feature of markings that direct the user to the next steps that the user has to perform with the device. With the exception of these designations, the apparatus is substantially the same as in the embodiment of FIG. 1 to 3 so that the same reference numbers are used for the same ingredients. These are some additional ingredients, as will be seen in the following description.

Naprava, ki jo kažejo skice sl. 32 do 34, ima pokrov 700, ki je zgibno priključen k ostalemu delu naprave za zasučno gibanje okoli osi 701. Zobnika 23 in 25 in pridružene sestavine so pokriti s hrbtno steno 702. Ta poteka po vsej hrbtni strani naprave, toda v skicah je vsa, razen malega dela, odrezana, da je olajšano razumevanje. Vzvod 24 je opremljen z ločnim podaljškom 703, na katerega enem robu je oblikovan greben 704. Podaljšek 703 nosi označitve v obliki navodil uporabniku, v tem primeru pojasnilne besede ODPRI POKROV, PRITISNI GUMB, VDIHNI. Ko sta vzvod 24 in s tem podaljšek 703 v zadevnih položajih, je vsakokrat ena od teh pojasnilnih besed vidna skozi okence 705 v hrbtni steni 702. Skrajni konec podaljška 703 tvori pritisni gumb 706. Konec vzvoda 24, ki je oddaljen od podaljška 703, nosi jezik 707, ki je zasučen z njim.The apparatus shown in the drawings of FIG. 32 to 34, the lid 700 is articulated to the rest of the rotary device about the axis 701. The gears 23 and 25 and the associated components are covered by the back wall 702. This runs all over the back of the device, but in the drawings all , except for a small part cut away to make it easier to understand. The lever 24 is provided with a separate extension 703, on one edge of which is formed a ridge 704. The extension 703 bears the markings in the form of instructions to the user, in this case the explanatory words OPEN COVERS, PRESS BUTTON, INHALES. When the lever 24 and thus the extension 703 are in the respective positions, each of these explanatory words is each time visible through the window 705 in the back wall 702. The extreme end of the extension 703 forms a push button 706. The end of the lever 24, which is away from the extension 703, bears tongue 707 twisted with it.

Skica sl. 32 kaže napravo v njenem mirovalnem stanju. V okencu 705 vidimo pojasnilni besedi ODPRI POKROV. Če bolnik tedaj odpre pokrov 700, se naprava s tem prevede v stanje po sl. 33. Ugotovimo lahko, da je vrhnji hrbtni rob pokrova zadel greben 704 in premaknil podaljšek 703 za določen kot, za toliko, da se v okencu 705 pojavi ukaz PRITISNI GUMB. Če uporabnik sedaj pritisne gumb 706, se zasuka vzvod 24, kar pomeni odprtje posodice s praškom, kot je bilo opisano v zvezi s skicami sl. 1 do 3. S tem se naprava prevede v stanje po sl. 34, v katerem v okencu 705 vidimo ukaz VDIHNI. Spet lahko ugotovimo, da v stanju po sl. 34 jezik 707 prodre gor. Ko uporabnik, potem ko je vdihnil, zapre pokrov, nastavek 708 na spodnji strani pokrova na osnovi te značilnosti zadene ob jezik 707, ki potisne vzvod 24 skupaj z njegovim podaljškom 703 nazaj v položaj, ki ga ponazarja sl. 32, tako da se spet prikaže ukaz ODPRI POKROV.Sketch of FIG. 32 shows the device in its idle state. In box 705 we see the explanatory words OPEN COVERS. If the patient then opens the lid 700, the device is thus converted to the state of FIG. 33. It can be noted that the upper dorsal edge of the lid hit the ridge 704 and moved the extension 703 by a certain angle until the PRESS BUTTON command appears in box 705. If the user now presses the button 706, the lever 24 is rotated, which means opening the powder container as described in connection with the drawings of FIG. 1 to 3. This translates the device into the state of FIG. 34, in which in box 705 we see the INSPIRATION command. It can again be noted that in the state of FIG. 34 language 707 penetrates up. When, after inhaling, the user closes the lid, the nozzle 708 on the underside of the lid, on the basis of this feature, hits the tongue 707, which pushes the lever 24 together with its extension 703 back to the position illustrated in FIG. 32 so that the OPEN COVERS command appears again.

Pravkar opisana naprava ne le da uporabniku daje zapovrstjo navodila, kako ravnati, tako da se zmanjša nevarnost, da bi se bolnik zmedel, temveč tudi onemogoča, da bi bolnik napravo uporabljal drugače kot je predvideno, saj gumb 706, ko smo ga enkrat pritisnili, ni več dosegljiv vse dotlej, dokler uporabnik ne zapre pokrova in ga spet odpre.The device just described not only instructs the user in the sequence how to act so as to reduce the risk of confusion for the patient, but also prevents the patient from using the device other than intended, since the button 706, once pressed, it is no longer available until the user closes the lid and opens it again.

V zgoraj opisanih izvedbenih primerih je govor o ustničnem kosu. Če bi morali napravo uprabljati za druge namene in ne za oralno vdihavanje, pride v poštev drugačen izstop, npr. nastavek za nos.In the embodiments described above, talking about the lip piece. If you need to use the device for purposes other than oral inhalation, a different exit should be considered, e.g. nosepiece.

Claims

PATENT APPLICATIONS

An inhalation device for use with a medication package (1, 201, 301, 401, 501, 601) comprising at least one powder drug container (2, 402), wherein the device comprises means that determine an opening station for said at least one container (2, 402), and an outlet (119, 319, 419) that cooperates with an open container (2, 402) through which the user can inhale the powder in the form of a powder from the open container (2, 402), characterized by said at least one container (2, 402) being arranged between two parts (3, 4, 203, 204, 403, 404) which are connected to each other so that they can be separated from each other and the device further comprises means for exfoliating peeling at the opening station for the purposes of opening the container.

Apparatus according to claim 1, characterized in that it is adapted for such use that said two parts (3, 4, 203, 204, 403, 404) are two films.

Apparatus according to claim 2, characterized in that it is adapted for use in such a way that the foils (3, 4, 203, 204, 403, 404) are elongate foils that define several drug containers (2, 402) spaced apart along their length, the apparatus being provided with a marking means (16, 416, 516) for marking each receptacle (2, 402) to be used to cooperate with the discharge (119, 319, 419).

Apparatus according to claim 3, characterized in that it is adapted for such use that one of the foils is a base foil (3, 203, 403) having several pockets (2, 402) and the other of the foils is the roof foil (4, 204, 404), each pocket (2, 402) and the adjacent portion of the roof foil (4, 204, 404) determine respectively from the receptacles, the device comprising a drive means for pulling the roof foil (4, 204) , 404) and base films (3, 203, 403) apart from the opening station.

Apparatus according to claim 4, characterized in that said drive means comprises means (14, 214, 314, 414, 514, 614) for driving the roof foil to pull the roof foil (4, 204, 404).

Apparatus according to claim 4 or 5, characterized in that it comprises a rotating marking wheel (16, 416, 516) in which the recesses (17) are compatible, with the wheel (16, 416, 516) compatible with a pocket (1, 401, 501) with a medicament such that each well (17) accepts the respective pocket (2, 402).

Apparatus according to claim 6, characterized in that the marking wheel (16, 416, 516) and the means (14, 214, 314, 414, 514, 614) for driving the roof foil are interconnected connected so that the rotation of one is aligned with the rotation of the other.

Apparatus according to claim 7, characterized in that the marking wheel (16, 416, 516) and the means (14, 214, 314, 414, 514, 614) are interconnected by means of a slip clutch (50) .

Device according to claim 8, characterized in that the slip clutch comprises a first gear part (63) which is movable with a marking wheel (16) and has a toothed surface (65), and a second gear tooth part (64) which is movable. with means (14) for driving the roof foil and having a toothed surface (66) in the engagement ratio with the toothed surface (65) of said first gear part (63), wherein one of the toothed surfaces (65, 66) has a toothed part (68) , which is movable back and forth with respect to the rest of the toothed surface of which it is a part.

Device according to claim 8, characterized in that the slip coupling comprises a first coupling means (811) movable with a marking wheel (416) and a second coupling means (810) movable with the drive means (414) the roof foil, wherein one of the coupling means (810) comprises an annular set of ribs (814) and the other of the coupling means (811) comprises means (818) which engage grippingly with the ribs (814) when between two coupling means (810) , 811) acts less than a predetermined force, and which with respect to the ribs (814) slip when a force equal to or greater than a predetermined force occurs.

Apparatus according to claim 7, characterized in that the cover film drive means (414) comprises a wheel (474) supported by the cover film (404), said wheel (474) having a winding surface whose diameter is decreases as the tension in the cover film (404) increases.

Apparatus according to claim 11, characterized in that said wheel (474) comprises several flexible feeding arms (476), each projecting from it at a certain angle to the radius.

Apparatus according to claim 4, characterized in that it comprises a marking means (250, 252) which is interposed between the adjacent pockets and causes each pocket to move in contact with the discharge (220).

Apparatus according to claim 5, characterized in that the cover film drive means comprises a pair of drive wheels (314a, 314b) which accept the cover film in a drive sense.

Apparatus according to claim 14, characterized in that said drive wheels (314a, 314b) are gears having interconnected teeth.

Apparatus according to claim 4, characterized in that it comprises means (622, 623) for guiding the cover film and the base film along separate paths at the opening station, the paths being again joined downstream of the opening station, said drive means (613, 614) arranged for the point where the paths merge again, and acts to drive both the umbrella and the base foil.

Device according to claim 16, characterized in that said drive means comprises two gear wheels (514a, 514b) which have mutually cooperating teeth.

Apparatus according to any one of claims 4 to 17, characterized in that it comprises at least one chamber (611) for receiving the elongated package (601) with the medicament before opening and for receiving the base film and the cover film after their peeling separation.

Apparatus according to claim 18, characterized in that the elongated drug package (1) and / or the base foil (3) are held in a twisted shape by means of flexible roll molders (28).

20. A device according to any preceding claim, which operates in several steps, characterized in that it comprises a pointing means (705, 706) adapted to show the user a instruction for the next step when the preceding step has been performed.

21. The device according to claim 20, characterized in that the indicating means (705, 706) surrounds an indicator portion carrying several explanatory fields, each of which forms a instruction for the user, the indicator portion being movable for a given step, which executes to display a caption indicating the next step.

22. A package (1, 201, 301, 401, 501, 601) comprising a medicament for use in an inhalation device, the package comprising an elongated ribbon, characterized in that said elongated ribbon is made of a base film (3, 203, 403) ), which has several recesses (2, 402) spaced along its length, and a covering foil (4, 204, 404) that is airtight but detachably connected to the former to determine multiple receptacles, each receptacle containing an inhalable drug in powder form.

A medicament package according to claim 22, characterized in that the strip (401) is flexible enough to roll into a roll.

Drug package according to claim 22 or 23, characterized in that the base film (403) and the cover film (404) have leading end sections which are not connected to one another.

A medicament package according to claim 24, characterized in that at least one of said leading end sections is provided with means (404a) allowing it to be connected to the twisting means.

26. A medicament package according to any one of claims 22 to 25, characterized in that the airtight joint between the base (403) and the cover film (404) extends over their entire width.