SI3710457T1 - Zaviralci imunoproteasoma - Google Patents

Zaviralci imunoproteasoma

Info

Publication number
SI3710457T1
SI3710457T1 SI201830791T SI201830791T SI3710457T1 SI 3710457 T1 SI3710457 T1 SI 3710457T1 SI 201830791 T SI201830791 T SI 201830791T SI 201830791 T SI201830791 T SI 201830791T SI 3710457 T1 SI3710457 T1 SI 3710457T1
Authority
SI
Slovenia
Prior art keywords
immunoproteasome inhibitors
immunoproteasome
inhibitors
Prior art date
Application number
SI201830791T
Other languages
English (en)
Inventor
Yan Lou
Timothy Duncan Owens
Kenneth Albert Brameld
David Michael Goldstein
Original Assignee
Principia Biopharma Inc.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Principia Biopharma Inc., filed Critical Principia Biopharma Inc.,
Publication of SI3710457T1 publication Critical patent/SI3710457T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/027Organoboranes and organoborohydrides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI201830791T 2017-11-16 2018-11-14 Zaviralci imunoproteasoma SI3710457T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762587375P 2017-11-16 2017-11-16
PCT/US2018/061132 WO2019099576A1 (en) 2017-11-16 2018-11-14 Immunoproteasome inhibitors
EP18812554.6A EP3710457B1 (en) 2017-11-16 2018-11-14 Immunoproteasome inhibitors

Publications (1)

Publication Number Publication Date
SI3710457T1 true SI3710457T1 (sl) 2023-02-28

Family

ID=64572584

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201830791T SI3710457T1 (sl) 2017-11-16 2018-11-14 Zaviralci imunoproteasoma

Country Status (18)

Country Link
US (1) US12024531B2 (sl)
EP (1) EP3710457B1 (sl)
JP (1) JP7333321B2 (sl)
KR (1) KR102647050B1 (sl)
CN (1) CN111491939B (sl)
AU (1) AU2018369787B2 (sl)
CA (1) CA3080958A1 (sl)
DK (1) DK3710457T3 (sl)
ES (1) ES2928787T3 (sl)
HR (1) HRP20221292T1 (sl)
HU (1) HUE060020T2 (sl)
LT (1) LT3710457T (sl)
MX (1) MX2020005036A (sl)
PL (1) PL3710457T3 (sl)
PT (1) PT3710457T (sl)
RS (1) RS63666B1 (sl)
SI (1) SI3710457T1 (sl)
WO (1) WO2019099576A1 (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018210839B2 (en) 2017-01-18 2022-01-20 Principia Biopharma Inc. Immunoproteasome inhibitors
CA3080949C (en) 2017-11-16 2024-04-16 Principia Biopharma Inc. Immunoproteasome inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US4963655A (en) 1988-05-27 1990-10-16 Mayo Foundation For Medical Education And Research Boron analogs of amino acid/peptide protease inhibitors
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
IL111175A0 (en) * 1993-10-07 1994-12-29 Du Pont Merck Pharma Electrophilic peptide analogs as inhibitors of trypsin-like serine proteases and pharmaceutical compositions containing them
US6083903A (en) 1994-10-28 2000-07-04 Leukosite, Inc. Boronic ester and acid compounds, synthesis and uses
US7576206B2 (en) 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
RU2379315C2 (ru) 2004-02-23 2010-01-20 Трастиз Оф Тафтс Колледж Ингибиторы дипептидилпептидазы iv
EP2793900B1 (en) 2011-12-22 2018-08-22 Ares Trading S.A. Alpha-amino boronic acid derivatives, selective immunoproteasome inhibitors
BR112015001213A2 (pt) * 2012-07-20 2018-05-22 Cleave Biosciences Inc pirimidinas fundidas como inibidores de complexo p97
WO2015195950A1 (en) 2014-06-20 2015-12-23 Principia Biophamram Inc. Lmp7 inhibitors
JP6662865B2 (ja) * 2014-10-01 2020-03-11 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung ボロン酸誘導体
AU2018210839B2 (en) 2017-01-18 2022-01-20 Principia Biopharma Inc. Immunoproteasome inhibitors
CA3080949C (en) 2017-11-16 2024-04-16 Principia Biopharma Inc. Immunoproteasome inhibitors

Also Published As

Publication number Publication date
EP3710457A1 (en) 2020-09-23
LT3710457T (lt) 2022-11-10
DK3710457T3 (da) 2022-10-24
ES2928787T3 (es) 2022-11-22
RS63666B1 (sr) 2022-11-30
HRP20221292T1 (hr) 2022-12-23
AU2018369787A1 (en) 2020-05-14
US12024531B2 (en) 2024-07-02
CA3080958A1 (en) 2019-05-23
CN111491939A (zh) 2020-08-04
AU2018369787B2 (en) 2023-04-20
WO2019099576A1 (en) 2019-05-23
PL3710457T3 (pl) 2023-02-20
JP7333321B2 (ja) 2023-08-24
KR102647050B1 (ko) 2024-03-14
PT3710457T (pt) 2022-10-25
HUE060020T2 (hu) 2023-01-28
MX2020005036A (es) 2020-08-17
CN111491939B (zh) 2023-12-26
EP3710457B1 (en) 2022-08-03
US20230133165A1 (en) 2023-05-04
KR20200090810A (ko) 2020-07-29
JP2021503467A (ja) 2021-02-12

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