SI3519382T1 - Izboljšan postopek za pripravo lakozamida - Google Patents
Izboljšan postopek za pripravo lakozamidaInfo
- Publication number
- SI3519382T1 SI3519382T1 SI201731033T SI201731033T SI3519382T1 SI 3519382 T1 SI3519382 T1 SI 3519382T1 SI 201731033 T SI201731033 T SI 201731033T SI 201731033 T SI201731033 T SI 201731033T SI 3519382 T1 SI3519382 T1 SI 3519382T1
- Authority
- SI
- Slovenia
- Prior art keywords
- lacosamide
- preparation
- improved process
- improved
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B51/00—Introduction of protecting groups or activating groups, not provided for in the preceding groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201621033097 | 2016-09-28 | ||
| EP17855088.5A EP3519382B1 (en) | 2016-09-28 | 2017-06-12 | An improved process for the preparation of lacosamide |
| PCT/IB2017/053448 WO2018060781A1 (en) | 2016-09-28 | 2017-06-12 | An improved process for the preparation of lacosamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3519382T1 true SI3519382T1 (sl) | 2022-02-28 |
Family
ID=61759364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201731033T SI3519382T1 (sl) | 2016-09-28 | 2017-06-12 | Izboljšan postopek za pripravo lakozamida |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10414720B2 (sl) |
| EP (1) | EP3519382B1 (sl) |
| AU (1) | AU2017336606A1 (sl) |
| BR (1) | BR112018015215A2 (sl) |
| ES (1) | ES2902653T3 (sl) |
| HU (1) | HUE057637T2 (sl) |
| PL (1) | PL3519382T3 (sl) |
| PT (1) | PT3519382T (sl) |
| SI (1) | SI3519382T1 (sl) |
| WO (1) | WO2018060781A1 (sl) |
| ZA (1) | ZA201805871B (sl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018159028A1 (ja) * | 2017-03-01 | 2018-09-07 | 株式会社エーピーアイ コーポレーション | Ｎ－ベンジル－２－ブロモ－３－メトキシプロピオン酸アミド及びその中間体の製造方法 |
| CN114685317A (zh) * | 2020-12-25 | 2022-07-01 | 成都硕德药业有限公司 | 一种治疗癫痫的药物的制备方法 |
| CN115616118B (zh) * | 2022-12-19 | 2023-02-28 | 北京澳合药物研究院有限公司 | 一种高效分离并检测d-丝氨酸中有关物质的高效液相色谱法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1642889A1 (en) * | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
| WO2009146325A1 (en) * | 2008-05-28 | 2009-12-03 | Pliva Hrvatska D.O.O. | Polymorphic and amorphous forms of lacosamide and amorphous compositions |
| US8759582B2 (en) | 2010-02-08 | 2014-06-24 | Natco Pharma Limited | Process for the preparation of lacosamide |
| US20130123537A1 (en) * | 2010-05-17 | 2013-05-16 | K a s s Narayan Garimella | Process for the preparation of lacosamide |
| US20130102811A1 (en) | 2010-07-02 | 2013-04-25 | Sun Pharmaceutical Industries Ltd | Process for the preparation of lacosamide |
| WO2012051551A1 (en) * | 2010-10-15 | 2012-04-19 | Nektar Therapeutics | N-optionally substituted aryl-2-oligomer-3-alkoxypropionamides |
| US9718765B1 (en) * | 2016-06-21 | 2017-08-01 | Sci Pharmtech, Inc. | Process for preparation of optically pure N-substituted-3-methoxypropionic acid derivatives |
-
2017
- 2017-06-12 US US16/076,486 patent/US10414720B2/en not_active Expired - Fee Related
- 2017-06-12 EP EP17855088.5A patent/EP3519382B1/en active Active
- 2017-06-12 PT PT178550885T patent/PT3519382T/pt unknown
- 2017-06-12 SI SI201731033T patent/SI3519382T1/sl unknown
- 2017-06-12 BR BR112018015215-3A patent/BR112018015215A2/pt not_active Application Discontinuation
- 2017-06-12 AU AU2017336606A patent/AU2017336606A1/en not_active Abandoned
- 2017-06-12 ES ES17855088T patent/ES2902653T3/es active Active
- 2017-06-12 PL PL17855088T patent/PL3519382T3/pl unknown
- 2017-06-12 WO PCT/IB2017/053448 patent/WO2018060781A1/en unknown
- 2017-06-12 HU HUE17855088A patent/HUE057637T2/hu unknown
-
2018
- 2018-08-31 ZA ZA2018/05871A patent/ZA201805871B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3519382A4 (en) | 2020-06-24 |
| EP3519382A1 (en) | 2019-08-07 |
| EP3519382B1 (en) | 2021-10-27 |
| WO2018060781A1 (en) | 2018-04-05 |
| ES2902653T3 (es) | 2022-03-29 |
| US10414720B2 (en) | 2019-09-17 |
| PL3519382T3 (pl) | 2022-03-21 |
| AU2017336606A1 (en) | 2018-08-16 |
| ZA201805871B (en) | 2019-07-31 |
| BR112018015215A2 (pt) | 2018-12-11 |
| US20190047944A1 (en) | 2019-02-14 |
| HUE057637T2 (hu) | 2022-06-28 |
| PT3519382T (pt) | 2021-12-06 |
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