SI3362056T1 - Aminotiolestrske spojine ali njihove farmacevtsko sprejemljive soli za uporabo v zdravljenju raka - Google Patents

Aminotiolestrske spojine ali njihove farmacevtsko sprejemljive soli za uporabo v zdravljenju raka

Info

Publication number
SI3362056T1
SI3362056T1 SI201631135T SI201631135T SI3362056T1 SI 3362056 T1 SI3362056 T1 SI 3362056T1 SI 201631135 T SI201631135 T SI 201631135T SI 201631135 T SI201631135 T SI 201631135T SI 3362056 T1 SI3362056 T1 SI 3362056T1
Authority
SI
Slovenia
Prior art keywords
cancer
treatment
pharmaceutically acceptable
acceptable salts
aminothiolester
Prior art date
Application number
SI201631135T
Other languages
English (en)
Inventor
Ismail Ceylan
Gerry Quash
Mileidys Perez-Alea
Guillaume Martin
Original Assignee
Advanced Biodesign "Les allees du Parc"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Biodesign "Les allees du Parc" filed Critical Advanced Biodesign "Les allees du Parc"
Publication of SI3362056T1 publication Critical patent/SI3362056T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/131Amines acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4453Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SI201631135T 2015-10-15 2016-10-14 Aminotiolestrske spojine ali njihove farmacevtsko sprejemljive soli za uporabo v zdravljenju raka SI3362056T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15306649 2015-10-15
EP16784831.6A EP3362056B1 (en) 2015-10-15 2016-10-14 Aminothiolester compounds or pharmaceutically acceptable salts thereof, for use in the treatment of cancer
PCT/EP2016/074697 WO2017064247A1 (en) 2015-10-15 2016-10-14 Aminothiolester compounds or pharmaceutically acceptable salts thereof, for use in the treatment of cancer

Publications (1)

Publication Number Publication Date
SI3362056T1 true SI3362056T1 (sl) 2021-05-31

Family

ID=54360385

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201631135T SI3362056T1 (sl) 2015-10-15 2016-10-14 Aminotiolestrske spojine ali njihove farmacevtsko sprejemljive soli za uporabo v zdravljenju raka

Country Status (21)

Country Link
US (2) US20180296548A1 (sl)
EP (1) EP3362056B1 (sl)
JP (1) JP7062593B2 (sl)
CN (1) CN108348485A (sl)
AR (1) AR106352A1 (sl)
CA (1) CA3001204C (sl)
CY (1) CY1123950T1 (sl)
DK (1) DK3362056T3 (sl)
ES (1) ES2867965T3 (sl)
HK (1) HK1251476A1 (sl)
HR (1) HRP20210359T1 (sl)
HU (1) HUE053725T2 (sl)
IL (1) IL258610B (sl)
LT (1) LT3362056T (sl)
MX (1) MX2018004380A (sl)
PL (1) PL3362056T3 (sl)
PT (1) PT3362056T (sl)
RS (1) RS61630B1 (sl)
SI (1) SI3362056T1 (sl)
WO (1) WO2017064247A1 (sl)
ZA (1) ZA201802399B (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101653881B1 (ko) * 2014-11-25 2016-09-02 (주)삼양세라텍 직접 가열식 온간 등방압 프레스
EP4035666A1 (en) * 2021-01-29 2022-08-03 Advanced Biodesign Aminothiolester compound or derivative thereof for use as an immunomodulatory agent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011059D0 (en) * 2000-05-08 2000-06-28 Pharmacia & Upjohn Spa Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione
FR2809727B1 (fr) * 2000-05-31 2002-07-26 Galderma Res & Dev Nouveaux composes aminothiolesters, compositions pharmaceutiques et cosmetiques les contenant et utilisations
CA2842228A1 (en) * 2011-07-15 2013-01-24 University Health Network Combination treatment for cancer
US9394233B2 (en) * 2012-03-01 2016-07-19 Cincinnati Children's Hospital Medical Center ROS-activated compounds as selective anti-cancer therapeutics

Also Published As

Publication number Publication date
CY1123950T1 (el) 2022-05-27
DK3362056T3 (da) 2021-03-29
CN108348485A (zh) 2018-07-31
EP3362056A1 (en) 2018-08-22
WO2017064247A1 (en) 2017-04-20
CA3001204C (en) 2023-08-29
ES2867965T3 (es) 2021-10-21
MX2018004380A (es) 2018-05-11
AR106352A1 (es) 2018-01-03
PT3362056T (pt) 2021-04-22
US20180296548A1 (en) 2018-10-18
ZA201802399B (en) 2020-01-29
BR112018007310A2 (pt) 2018-10-23
JP7062593B2 (ja) 2022-05-06
HRP20210359T1 (hr) 2021-04-16
EP3362056B1 (en) 2021-02-24
HUE053725T2 (hu) 2021-07-28
HK1251476A1 (zh) 2019-02-01
JP2018536699A (ja) 2018-12-13
IL258610A (en) 2018-06-28
IL258610B (en) 2021-04-29
RS61630B1 (sr) 2021-04-29
CA3001204A1 (en) 2017-04-20
LT3362056T (lt) 2021-05-10
PL3362056T3 (pl) 2021-09-27
US20230149378A1 (en) 2023-05-18

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