SI3325453T1 - Postopki kemijske sinteze substituiranih 10H-fenotiazin-3,7-diaminskih spojin - Google Patents

Postopki kemijske sinteze substituiranih 10H-fenotiazin-3,7-diaminskih spojin

Info

Publication number
SI3325453T1
SI3325453T1 SI201631037T SI201631037T SI3325453T1 SI 3325453 T1 SI3325453 T1 SI 3325453T1 SI 201631037 T SI201631037 T SI 201631037T SI 201631037 T SI201631037 T SI 201631037T SI 3325453 T1 SI3325453 T1 SI 3325453T1
Authority
SI
Slovenia
Prior art keywords
phenothiazine
substituted
methods
chemical synthesis
diamine compounds
Prior art date
Application number
SI201631037T
Other languages
English (en)
Inventor
John Mervyn David Storey
Christopher Paul Larch
Steven John Kemp
Scott Clunas
Sarah Louise Nicoll
Helen Sarah Gibbard
Michael Simpson
James Peter Sinclair
Colin Marshall
Original Assignee
Wista Laboratories Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wista Laboratories Ltd. filed Critical Wista Laboratories Ltd.
Publication of SI3325453T1 publication Critical patent/SI3325453T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18[b, e]-condensed with two six-membered rings
    • C07D279/20[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
SI201631037T 2015-07-20 2016-07-20 Postopki kemijske sinteze substituiranih 10H-fenotiazin-3,7-diaminskih spojin SI3325453T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1512678.2A GB201512678D0 (en) 2015-07-20 2015-07-20 Methods of chemical synthesis
PCT/EP2016/067302 WO2017013174A1 (en) 2015-07-20 2016-07-20 Methods of chemical synthesis of substituted 10h-phenothiazine-3,7-diamine compounds
EP16745078.2A EP3325453B1 (en) 2015-07-20 2016-07-20 Methods of chemical synthesis of substituted 10h-phenothiazine-3,7-diamine compounds

Publications (1)

Publication Number Publication Date
SI3325453T1 true SI3325453T1 (sl) 2021-04-30

Family

ID=54013271

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201631037T SI3325453T1 (sl) 2015-07-20 2016-07-20 Postopki kemijske sinteze substituiranih 10H-fenotiazin-3,7-diaminskih spojin

Country Status (17)

Country Link
US (1) US10323010B2 (sl)
EP (1) EP3325453B1 (sl)
JP (1) JP6735810B2 (sl)
CN (1) CN107848992B (sl)
AU (1) AU2016296221B2 (sl)
BR (1) BR112018000498B1 (sl)
CA (1) CA2993123A1 (sl)
DK (1) DK3325453T3 (sl)
ES (1) ES2836492T3 (sl)
GB (1) GB201512678D0 (sl)
HR (1) HRP20202039T8 (sl)
MX (1) MX2018000462A (sl)
MY (1) MY189631A (sl)
PL (1) PL3325453T3 (sl)
PT (1) PT3325453T (sl)
SI (1) SI3325453T1 (sl)
WO (1) WO2017013174A1 (sl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3375777A1 (en) 2017-03-15 2018-09-19 MIKROCHEM spol. s.r.o. Method for preparation of 3,7-bis-(dimethylamino)-phenothiazin-5-ium chloride or bromide
CN112426521B (zh) * 2019-08-26 2023-08-01 广州威溶特医药科技有限公司 吩噻嗪类或其类似结构的化合物在制药中的新应用
US20220049102A1 (en) * 2019-09-21 2022-02-17 RK Pharma Solutions LLC Process for the Purification of Methylene Blue
CN114989113A (zh) * 2022-06-01 2022-09-02 山东科源制药股份有限公司 一种药用亚甲基蓝的精制方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4302013C1 (de) * 1993-01-26 1994-06-01 Uwe Dr Fiedeldei Verfahren zur Herstellung reiner Phenothiazinfarbstoffe
GB9506197D0 (en) 1995-03-27 1995-05-17 Hoffmann La Roche Inhibition of tau-tau association.
JP2000198766A (ja) * 1999-01-07 2000-07-18 Chemiprokasei Kaisha Ltd N,n―ジ分岐アルキルアニリン類の製造方法
BR0016937A (pt) 2000-01-07 2002-12-31 Warner Lambert Co Compostos tricìclicos e método de tratar herpesvìrus
GB0101049D0 (en) 2001-01-15 2001-02-28 Univ Aberdeen Materials and methods relating to protein aggregation in neurodegenerative disease
US7777051B2 (en) * 2003-05-13 2010-08-17 Icagen, Inc. Asymmetric benzimidazoles and related compounds as potassium channel modulators
GB0322756D0 (en) 2003-09-29 2003-10-29 Univ Aberdeen Methods of chemical synthesis
AU2013200732B2 (en) 2006-03-29 2015-04-09 Wista Laboratories Ltd. 3,7-diamino-10H-phenothiazine salts and their use
CN101460222B (zh) 2006-03-29 2013-12-04 维斯塔实验室有限公司 锍化合物及其用途
CN104119294B (zh) * 2006-03-29 2018-10-30 维斯塔实验室有限公司 3,7-二氨基-10h-吩噻嗪化合物的制备方法
CN101511803B (zh) * 2006-07-11 2012-10-31 维斯塔实验室有限公司 二氨基吩噻嗪*化合物的合成和/或纯化方法
FR2920775B1 (fr) 2007-09-07 2009-11-06 Pharma Hydro Dev P H D Soc Par Nouveaux composes diaminophenothiazine, leur procede de preparation et leurs utilisations.
EP2370407B1 (en) * 2008-12-19 2014-06-18 Bristol-Myers Squibb Company Carbazole and carboline kinase inhibitors
SI2673266T1 (sl) 2011-02-11 2016-11-30 Wista Laboratories Ltd. Fenotiazin diaminijeve soli in njihova uporaba
WO2012135402A1 (en) * 2011-03-29 2012-10-04 Prostetta Antiviral Inc. Antiviral compounds

Also Published As

Publication number Publication date
PL3325453T3 (pl) 2021-04-19
CN107848992B (zh) 2022-05-31
JP6735810B2 (ja) 2020-08-05
PT3325453T (pt) 2020-12-15
US20180208565A1 (en) 2018-07-26
US10323010B2 (en) 2019-06-18
EP3325453B1 (en) 2020-10-21
AU2016296221A1 (en) 2018-02-22
JP2018528170A (ja) 2018-09-27
CN107848992A (zh) 2018-03-27
AU2016296221B2 (en) 2020-05-07
BR112018000498B1 (pt) 2023-02-07
ES2836492T3 (es) 2021-06-25
EP3325453A1 (en) 2018-05-30
WO2017013174A1 (en) 2017-01-26
MX2018000462A (es) 2018-04-30
HRP20202039T8 (hr) 2021-07-23
MY189631A (en) 2022-02-22
DK3325453T3 (da) 2020-11-02
HRP20202039T1 (hr) 2021-02-19
CA2993123A1 (en) 2017-01-26
BR112018000498A2 (pt) 2018-09-11
GB201512678D0 (en) 2015-08-26

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