SI2893936T1 - Glutaril histamin za zdravljenje in profilakso bolezni, ki jih povzročajo virusi, ki vsebujejo (+)RNA - Google Patents

Glutaril histamin za zdravljenje in profilakso bolezni, ki jih povzročajo virusi, ki vsebujejo (+)RNA Download PDF

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Publication number
SI2893936T1
SI2893936T1 SI201331011T SI201331011T SI2893936T1 SI 2893936 T1 SI2893936 T1 SI 2893936T1 SI 201331011 T SI201331011 T SI 201331011T SI 201331011 T SI201331011 T SI 201331011T SI 2893936 T1 SI2893936 T1 SI 2893936T1
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Slovenia
Prior art keywords
pharmaceutically acceptable
virus
acceptable salt
glutaryl
histamine
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SI201331011T
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English (en)
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Vladimir Evgenievich Nebolsin
Sergei Vladimirovich Borisevich
Andrei Yurievich Egorov
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Obschestvo S Ogranichennoi Otvetstvennostiyu "Pharmenterprises"
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Publication of SI2893936T1 publication Critical patent/SI2893936T1/sl

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/417Imidazole-alkylamines, e.g. histamine, phentolamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (14)

  1. Glutaril histamin za zdravljenje in profilakso bolezni, ki jih povzročajo virusi, ki vsebujejo (+)RNA Patentni zahtevki
    1. Glutaril histamin ali njegova farmacevtsko sprejemljiva sol, za uporabo v preventivi ali zdravljenju bolezni, kijih povzročajo virusi, ki vsebujejo (+)RNA, ki pripadajo rodu Enterovirus ali rodu Flavivirus.
  2. 2. Glutaril histamin ali njegova farmacevtsko sprejemljiva sol, za uporabo po zahtevku 1, kjer je virus, ki pripada rodu Enterovirus izbran iz skupine, ki vsebuje rinoviruse, viruse Coxsackie in enteroviruse tip 71.
  3. 3. Glutaril histamin ali njegova farmacevtsko sprejemljiva sol, za uporabo po zahtevku 1, kjer so bolezni poslabšanja astme, kronična obstruktivna pljučna bolezen, bronhitis in mukoviscidoza, ki jih povzroča rinovirus.
  4. 4. Glutaril histamin ali njegova farmacevtsko sprejemljiva sol, za uporabo po zahtevku 1, kjer je virus, ki pripada rodu Flavivirus izbran iz skupine, ki vsebuje virus zahodnega Nila, virus denge, virus encefalitisa, ki ga prenašajo klopi, Saint-Louisov virus encefalitisa, Murray Valleyev virus encefalitisa in virus rumene mrzlice.
  5. 5. Glutaril histamin ali njegova farmacevtsko sprejemljiva sol, za uporabo po kateremkoli zahtevku od 1 do 4, kjer je glutaril histamin ali njegova farmacevtsko sprejemljiva sol administrirana v trdni dozirni obliki.
  6. 6. Glutaril histamin ali njegova farmacevtsko sprejemljiva sol, za uporabo po kateremkoli zahtevku od 1 do 5, kjer je odmerek glutaril histamina ali njegove farmacevtsko sprejemljive soli od 0,1 do 10 mg/kg telesne teže pacienta, ki mu administriramo glutaril histamin ali njegovo farmacevtsko sprejemljivo sol.
  7. 7. Glutaril histamin ali njegova farmacevtsko sprejemljiva sol, za uporabo po kateremkoli zahtevku od 1 do 6, kjer je en odmerek glutaril histamina 100 mg.
  8. 8. Glutaril histamin ali njegova farmacevtsko sprejemljiva sol, za uporabo po kateremkoli zahtevku od 1 do 7, kjer je čas trajanja administracije glutaril histamina od 5 dni do 12 mesecev.
  9. 9. Farmacevtski sestavek za uporabo v preventivi ali zdravljenju bolezni, ki jih povzročajo virusi, ki vsebujejo (+)RNA, ki pripadajo rodu Enterovirus ali rodu Flavivirus, kjer farmacevtski sestavek vsebuje učinkovito količino glutaril histamina ali njegove farmacevtsko sprejemljive soli.
  10. 10. Farmacevtski sestavek po zahtevku 9, za uporabo po zahtevku 9, kjer je učinkovita glutaril histamina ali njegove farmacevtsko sprejemljive soli od 0,1 do 10 mg/kg telesne teže pacienta, ki mu farmacevtski sestavek administriramo.
  11. 11. Farmacevtski sestavek po zahtevku 9, za uporabo po zahtevku 9 ali 10, kjer je odmerek glutaril histamina 100 mg, kadar je administriran enkrat dnevno.
  12. 12. Farmacevtski sestavek po zahtevku 9, za uporabo po kateremkoli zahtevku od 9 do 11, kjer je virus, ki pripada rodu Entero virus izbran iz skupine, ki vsebuje rinoviruse, viruse Coxsackie in enteroviruse tip 71.
  13. 13. Farmacevtski sestavek po zahtevku 9, za uporabo po kateremkoli zahtevku od 9 to 11, kjer je virus, ki pripada rodu Flavivirus izbran iz skupine, ki vsebuje virus zahodnega Nila, virus denge, virus encefalitisa, ki ga prenašajo klopi, Saint-Louisov virus encefalitisa, Murray Valleyev virus encefalitisa in virus rumene mrzlice.
  14. 14. Farmacevtski sestavek po zahtevku 9, za uporabo po kateremkoli zahtevku od 9 to 11, kjer so bolezni poslabšanja astme, kronična obstruktivna pljučna bolezen, bronhitis in mukoviscidoza, kijih povzroča rinovirus.
SI201331011T 2012-08-30 2013-08-29 Glutaril histamin za zdravljenje in profilakso bolezni, ki jih povzročajo virusi, ki vsebujejo (+)RNA SI2893936T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2012137097/15A RU2518314C2 (ru) 2012-08-30 2012-08-30 Способ и средство активации irf-3 для лечения и профилактики заболеваний, вызываемых (+) phk-содержащими вирусами
EP13833080.8A EP2893936B1 (en) 2012-08-30 2013-08-29 Glutaryl histamine for the treatment and prophylaxis of diseases caused by (+)rna-containing viruses
PCT/RU2013/000751 WO2014035297A1 (ru) 2012-08-30 2013-08-29 Способ и средство для лечения и профилактики заболеваний, вызываемых (+) рнк-содержащими вирусами

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SI2893936T1 true SI2893936T1 (sl) 2018-07-31

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SI201331011T SI2893936T1 (sl) 2012-08-30 2013-08-29 Glutaril histamin za zdravljenje in profilakso bolezni, ki jih povzročajo virusi, ki vsebujejo (+)RNA

Country Status (17)

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US (1) US9820970B2 (sl)
EP (1) EP2893936B1 (sl)
JP (1) JP6328638B2 (sl)
CN (1) CN104684569B (sl)
CA (1) CA2883908C (sl)
CY (1) CY1120158T1 (sl)
DK (1) DK2893936T3 (sl)
EA (1) EA028541B1 (sl)
ES (1) ES2667342T3 (sl)
HK (1) HK1210025A1 (sl)
HU (1) HUE036805T2 (sl)
LT (1) LT2893936T (sl)
PL (1) PL2893936T3 (sl)
PT (1) PT2893936T (sl)
RU (1) RU2518314C2 (sl)
SI (1) SI2893936T1 (sl)
WO (1) WO2014035297A1 (sl)

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US9504673B2 (en) * 2009-05-21 2016-11-29 LTD “Valenta-Intellekt” Agent for the prophylaxis and treatment of highly pathogenic infectious diseases
RU2628800C2 (ru) * 2014-03-12 2017-08-22 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Амидные соединения, способы получения, применение в качестве средств для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами
RU2746692C1 (ru) * 2020-04-14 2021-04-19 Общество С Ограниченной Ответственностью "Валента - Интеллект" Новые составы 2-(имидазол-4-ил)-этанамида пентандиовой-1,5 кислоты для лечения и профилактики вирусных заболеваний
RU2770521C2 (ru) * 2020-02-11 2022-04-18 Общество С Ограниченной Ответственностью "Валента-Интеллект" Жидкая лекарственная форма для лечения и профилактики гриппа и орви
RU2744854C1 (ru) * 2020-02-11 2021-03-16 Общество С Ограниченной Ответственностью "Валента-Интеллект" Жидкая лекарственная форма для лечения и профилактики гриппа и орви
RU2770518C2 (ru) * 2020-02-11 2022-04-18 Общество С Ограниченной Ответственностью "Валента-Интеллект" Жидкая лекарственная форма для лечения и профилактики гриппа и орви
CN114984030A (zh) * 2022-06-23 2022-09-02 中国人民解放军海军军医大学 利巴韦林在制备抗蜱传脑炎病毒药物中的应用

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RU2141483C1 (ru) * 1997-07-04 1999-11-20 Небольсин Владимир Евгеньевич Производные пептидов или их фармацевтически приемлемые соли, способ их получения, применение и фармацевтическая композиция
JP3838034B2 (ja) * 1997-10-13 2006-10-25 大塚製薬株式会社 C型肝炎治療効果の改善剤及びその応用
KR20010043004A (ko) * 1998-04-30 2001-05-25 개리 이. 프라이드만 피코르나 바이러스 억제 화합물, 그의 제조 방법 및 용도
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US9504673B2 (en) * 2009-05-21 2016-11-29 LTD “Valenta-Intellekt” Agent for the prophylaxis and treatment of highly pathogenic infectious diseases
RU2496512C1 (ru) * 2012-03-14 2013-10-27 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Способ лечения вирусного гепатита с

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Publication number Publication date
CA2883908C (en) 2019-06-04
EP2893936A1 (en) 2015-07-15
CN104684569B (zh) 2018-03-02
PT2893936T (pt) 2018-05-02
DK2893936T3 (en) 2018-05-28
ES2667342T3 (es) 2018-05-10
JP6328638B2 (ja) 2018-05-23
LT2893936T (lt) 2018-06-25
EP2893936B1 (en) 2018-04-04
US20150209330A1 (en) 2015-07-30
RU2012137097A (ru) 2014-03-10
EA028541B1 (ru) 2017-11-30
HK1210025A1 (en) 2016-04-15
HUE036805T2 (hu) 2018-07-30
CY1120158T1 (el) 2018-12-12
WO2014035297A1 (ru) 2014-03-06
EA201590460A1 (ru) 2015-06-30
PL2893936T3 (pl) 2018-09-28
CN104684569A (zh) 2015-06-03
RU2518314C2 (ru) 2014-06-10
US9820970B2 (en) 2017-11-21
CA2883908A1 (en) 2014-03-06
EP2893936A4 (en) 2016-03-16
JP2015526513A (ja) 2015-09-10

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