SI2709988T1 - Postopek za pripravo (4,6-bis-dimetilamino-2- (4- (4- trifluorometilbenzoil-amino)benzil) primidin-5-il) ocetne kisline - Google Patents

Postopek za pripravo (4,6-bis-dimetilamino-2- (4- (4- trifluorometilbenzoil-amino)benzil) primidin-5-il) ocetne kisline

Info

Publication number
SI2709988T1
SI2709988T1 SI201231041T SI201231041T SI2709988T1 SI 2709988 T1 SI2709988 T1 SI 2709988T1 SI 201231041 T SI201231041 T SI 201231041T SI 201231041 T SI201231041 T SI 201231041T SI 2709988 T1 SI2709988 T1 SI 2709988T1
Authority
SI
Slovenia
Prior art keywords
trifluoromethylbenzoyl
pyrimidin
dimethylamino
benzyl
bis
Prior art date
Application number
SI201231041T
Other languages
English (en)
Inventor
Dehli Juan M. Rodriguez
Robert Hagenkoetter
Michael Schul
Christian Stange
Xiao-Jun Wang
Li Zhang
Oriol Massot
Original Assignee
Actimis Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actimis Pharmaceuticals, Inc. filed Critical Actimis Pharmaceuticals, Inc.
Publication of SI2709988T1 publication Critical patent/SI2709988T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SI201231041T 2011-05-16 2012-05-07 Postopek za pripravo (4,6-bis-dimetilamino-2- (4- (4- trifluorometilbenzoil-amino)benzil) primidin-5-il) ocetne kisline SI2709988T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161486363P 2011-05-16 2011-05-16
PCT/EP2012/058338 WO2012156221A1 (en) 2011-05-16 2012-05-07 Process for preparing [4,6-bis-dimethylamino-2-[4-(4-trifluoromethylbenzoyl-amino)benzyl]pyrimidin-5-yl]acetic acid
EP12718262.4A EP2709988B1 (en) 2011-05-16 2012-05-07 Process for preparing [4,6-bis-dimethylamino-2-[4-(4-trifluoromethylbenzoyl-amino)benzyl]pyrimidin-5-yl]acetic acid

Publications (1)

Publication Number Publication Date
SI2709988T1 true SI2709988T1 (sl) 2017-11-30

Family

ID=46025756

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201231041T SI2709988T1 (sl) 2011-05-16 2012-05-07 Postopek za pripravo (4,6-bis-dimetilamino-2- (4- (4- trifluorometilbenzoil-amino)benzil) primidin-5-il) ocetne kisline

Country Status (15)

Country Link
US (1) US8859770B2 (sl)
EP (2) EP2709988B1 (sl)
JP (1) JP5988253B2 (sl)
CY (1) CY1119348T1 (sl)
DK (1) DK2709988T3 (sl)
ES (1) ES2639045T3 (sl)
HK (1) HK1252529A1 (sl)
HR (1) HRP20171287T1 (sl)
HU (1) HUE034889T2 (sl)
LT (1) LT2709988T (sl)
PL (1) PL2709988T3 (sl)
PT (1) PT2709988T (sl)
RS (1) RS56326B1 (sl)
SI (1) SI2709988T1 (sl)
WO (1) WO2012156221A1 (sl)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1471057B1 (en) * 2003-04-25 2006-01-18 Actimis Pharmaceuticals, Inc. Pyrimidinylacetic acid derivatives useful for the treatment of diseases mediated by CRTH2
EP2328876B1 (en) * 2008-09-02 2012-11-21 Actimis Pharmaceuticals, Inc., Isotopically enriched pyrimidin-5-yl acetic acid derivatives as crth2 antagonists

Also Published As

Publication number Publication date
PT2709988T (pt) 2017-09-08
HUE034889T2 (hu) 2018-03-28
JP5988253B2 (ja) 2016-09-07
HK1252529A1 (zh) 2019-05-31
JP2014515033A (ja) 2014-06-26
US20140187779A1 (en) 2014-07-03
ES2639045T3 (es) 2017-10-25
EP2709988B1 (en) 2017-07-05
HRP20171287T1 (hr) 2017-11-17
RS56326B1 (sr) 2017-12-29
EP2709988A1 (en) 2014-03-26
EP3293180A1 (en) 2018-03-14
CY1119348T1 (el) 2018-03-07
LT2709988T (lt) 2017-10-10
WO2012156221A1 (en) 2012-11-22
PL2709988T3 (pl) 2018-04-30
DK2709988T3 (en) 2017-09-18
US8859770B2 (en) 2014-10-14

Similar Documents

Publication Publication Date Title
SI3683209T1 (sl) Postopek za pripravo ((5-(3-klorofenil)-3-hidroksipiridin-2-karbonil)-amino)ocetne kisline iz 5-((3-klorofenil)-3-kloro-piridin-2-il)-nitrila in postopek za pripravo derivatov 5-((halofenil)-3-halo-piridin-2-il)-nitrila
IL230477A0 (en) Process for preparing 2,2-difluoroethanol
SG11201503291RA (en) Process for producing acetic acid
EP2661487A4 (en) BIOLOGICAL METHODS FOR PREPARING ADIPIC ACID
RS62542B1 (sr) 2-(2,4,5-supstituisani-anilino) pirimidinski derivati
EP2687510A4 (en) PROCESS FOR THE PREPARATION OF 2,3-DICHLORPYRIDINE
HK1201517A1 (en) Process for preparing quinoline derivatives
EP2797866A4 (en) PROCESS FOR THE PREPARATION OF 1,6-HEXANEDIOL
IL207526A0 (en) Process for preparing 2-amino-5-cyanobenzoic acid derivatives
EP2562152A4 (en) PROCESS FOR PREPARING 2,5-DIMETHYLPHENYL-ACETIC ACID
EP2675773A4 (en) PROCESS FOR THE PREPARATION OF CIS-1-CHLORO-3,3,3-TRIFLUOROPROPENE
IL227872A0 (en) A process for the preparation of n-converted phenylhydroxylamines
ZA201308894B (en) Process for preparing methacrylic acid
SG11201504643WA (en) Integrated process for making acetic acid
IL237203A0 (en) Process for decarboxylation of 5,3-bis(haloalkyl)-pyrazole-4-carboxylic acid derivatives
HK1204607A1 (en) Process for preparing 4-amino-5-biphenyl-4-yl-2-hydroxymethyl-2- methyl-pentanoic acid compounds 4--5--4--2--2--
EP2840088A4 (en) PROCESS FOR THE PREPARATION OF 5,6,4'-TRIHYDROXYFLAVONE-7-0-D-GLUCURONIC ACID
ZA201304938B (en) Process for producing nitrile-fatty acid compounds
ZA201405237B (en) Process for preparing formic acid
EP2531499A4 (en) PROCESS FOR THE PREPARATION OF VORICONAZOLE USING NEW INTERMEDIATES
HK1252529A1 (zh) 用於製備[4,6-雙-二甲氨基-2-[4-(4-三氟甲基苯甲酰基-氨基)苄基]嘧啶-5-基]乙酸的方法
PL2771328T3 (pl) Sposób otrzymywania 1,2-benzizotiazolin-3-onu
EP2761004A4 (en) BIOLOGICAL METHODS FOR PREPARING ADIPIC ACID
白髭修一 Expectation for Industry-University Cooperation
IL222929A0 (en) Process for preparing substituted 1, 3 - dihydro - 2h - indol - 2 - ones