PL2709988T3 - Proces przygotowania kwasu [4,6-bis-dimetyloamino-2-[4-(4- trifluorometylbenzoyl-amino)benzylo]pyrimidin-5-ylo] octowego - Google Patents

Proces przygotowania kwasu [4,6-bis-dimetyloamino-2-[4-(4- trifluorometylbenzoyl-amino)benzylo]pyrimidin-5-ylo] octowego

Info

Publication number
PL2709988T3
PL2709988T3 PL12718262T PL12718262T PL2709988T3 PL 2709988 T3 PL2709988 T3 PL 2709988T3 PL 12718262 T PL12718262 T PL 12718262T PL 12718262 T PL12718262 T PL 12718262T PL 2709988 T3 PL2709988 T3 PL 2709988T3
Authority
PL
Poland
Prior art keywords
trifluoromethylbenzoyl
pyrimidin
dimethylamino
benzyl
bis
Prior art date
Application number
PL12718262T
Other languages
English (en)
Inventor
Juan M. Rodriguez Dehli
Robert Hagenkoetter
Michael Schul
Christian Stange
Xiao-Jun Wang
Li Zhang
Oriol MASSOT
Original Assignee
Actimis Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actimis Pharmaceuticals, Inc. filed Critical Actimis Pharmaceuticals, Inc.
Publication of PL2709988T3 publication Critical patent/PL2709988T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL12718262T 2011-05-16 2012-05-07 Proces przygotowania kwasu [4,6-bis-dimetyloamino-2-[4-(4- trifluorometylbenzoyl-amino)benzylo]pyrimidin-5-ylo] octowego PL2709988T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161486363P 2011-05-16 2011-05-16
PCT/EP2012/058338 WO2012156221A1 (en) 2011-05-16 2012-05-07 Process for preparing [4,6-bis-dimethylamino-2-[4-(4-trifluoromethylbenzoyl-amino)benzyl]pyrimidin-5-yl]acetic acid
EP12718262.4A EP2709988B1 (en) 2011-05-16 2012-05-07 Process for preparing [4,6-bis-dimethylamino-2-[4-(4-trifluoromethylbenzoyl-amino)benzyl]pyrimidin-5-yl]acetic acid

Publications (1)

Publication Number Publication Date
PL2709988T3 true PL2709988T3 (pl) 2018-04-30

Family

ID=46025756

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12718262T PL2709988T3 (pl) 2011-05-16 2012-05-07 Proces przygotowania kwasu [4,6-bis-dimetyloamino-2-[4-(4- trifluorometylbenzoyl-amino)benzylo]pyrimidin-5-ylo] octowego

Country Status (15)

Country Link
US (1) US8859770B2 (pl)
EP (2) EP2709988B1 (pl)
JP (1) JP5988253B2 (pl)
CY (1) CY1119348T1 (pl)
DK (1) DK2709988T3 (pl)
ES (1) ES2639045T3 (pl)
HK (1) HK1252529A1 (pl)
HR (1) HRP20171287T1 (pl)
HU (1) HUE034889T2 (pl)
LT (1) LT2709988T (pl)
PL (1) PL2709988T3 (pl)
PT (1) PT2709988T (pl)
RS (1) RS56326B1 (pl)
SI (1) SI2709988T1 (pl)
WO (1) WO2012156221A1 (pl)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1471057B1 (en) * 2003-04-25 2006-01-18 Actimis Pharmaceuticals, Inc. Pyrimidinylacetic acid derivatives useful for the treatment of diseases mediated by CRTH2
EP2328876B1 (en) * 2008-09-02 2012-11-21 Actimis Pharmaceuticals, Inc., Isotopically enriched pyrimidin-5-yl acetic acid derivatives as crth2 antagonists

Also Published As

Publication number Publication date
PT2709988T (pt) 2017-09-08
HUE034889T2 (hu) 2018-03-28
JP5988253B2 (ja) 2016-09-07
HK1252529A1 (zh) 2019-05-31
JP2014515033A (ja) 2014-06-26
US20140187779A1 (en) 2014-07-03
SI2709988T1 (sl) 2017-11-30
ES2639045T3 (es) 2017-10-25
EP2709988B1 (en) 2017-07-05
HRP20171287T1 (hr) 2017-11-17
RS56326B1 (sr) 2017-12-29
EP2709988A1 (en) 2014-03-26
EP3293180A1 (en) 2018-03-14
CY1119348T1 (el) 2018-03-07
LT2709988T (lt) 2017-10-10
WO2012156221A1 (en) 2012-11-22
DK2709988T3 (en) 2017-09-18
US8859770B2 (en) 2014-10-14

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