SI2656843T1 - Estri bendamustina in povezane spojine ter njihova medicinska uporaba - Google Patents

Estri bendamustina in povezane spojine ter njihova medicinska uporaba

Info

Publication number
SI2656843T1
SI2656843T1 SI201230205T SI201230205T SI2656843T1 SI 2656843 T1 SI2656843 T1 SI 2656843T1 SI 201230205 T SI201230205 T SI 201230205T SI 201230205 T SI201230205 T SI 201230205T SI 2656843 T1 SI2656843 T1 SI 2656843T1
Authority
SI
Slovenia
Prior art keywords
bendamustine
esters
related compounds
medical use
medical
Prior art date
Application number
SI201230205T
Other languages
English (en)
Inventor
Helmut Schickaneder
Armin Buschauer
Gunther Bernhardt
Christian Schickaneder
Michael Limmert
Stefan Huber
Original Assignee
Helmut Schickaneder
Christian Schickaneder
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helmut Schickaneder, Christian Schickaneder filed Critical Helmut Schickaneder
Publication of SI2656843T1 publication Critical patent/SI2656843T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms
SI201230205T 2012-04-26 2012-04-26 Estri bendamustina in povezane spojine ter njihova medicinska uporaba SI2656843T1 (sl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12165728.2A EP2656843B1 (en) 2012-04-26 2012-04-26 Esters of bendamustine and related compounds, and medical use thereof

Publications (1)

Publication Number Publication Date
SI2656843T1 true SI2656843T1 (sl) 2015-06-30

Family

ID=46045872

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201230205T SI2656843T1 (sl) 2012-04-26 2012-04-26 Estri bendamustina in povezane spojine ter njihova medicinska uporaba

Country Status (8)

Country Link
US (1) US8809549B2 (sl)
EP (1) EP2656843B1 (sl)
DK (1) DK2656843T3 (sl)
ES (1) ES2535511T3 (sl)
HR (1) HRP20150436T1 (sl)
PL (1) PL2656843T3 (sl)
PT (1) PT2656843E (sl)
SI (1) SI2656843T1 (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX365192B (es) * 2012-06-19 2019-05-23 Synbias Pharma Ag Derivados de bendamustina y compuestos relacionados, y uso medico de los mismos para la terapia de cancer.
EP2917183A1 (en) 2012-11-12 2015-09-16 Ignyta, Inc. Bendamustine derivatives and methods of using same
PT3130592T (pt) 2014-04-10 2019-11-21 Hubei Bio Pharmaceutical Industrial Tech Institute Inc Análogos do composto 4h-pirazolo[1,5-]benzimidazole como inibidores de parp
US11274092B2 (en) * 2016-02-24 2022-03-15 Acesion Pharma Aps Potassium channel inhibitors
CN111201019A (zh) 2017-10-05 2020-05-26 图贝药物有限公司 口服苯达莫司汀制剂

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
AU2009302493B2 (en) * 2008-10-08 2015-04-09 Cephalon Llc Processes for the preparation of bendamustine
MX2011005643A (es) 2008-12-03 2011-09-27 Astellas Deutschland Gmbh Formas de dosificacion oral de bendamustina.
CN101691359B (zh) 2009-09-30 2011-04-13 深圳万乐药业有限公司 一种高纯度的盐酸苯达莫司汀的合成方法
WO2011079193A2 (en) * 2009-12-23 2011-06-30 Dr. Reddy's Laboratories Ltd. Preparation of bendamustine and its salts
JO3659B1 (ar) 2010-06-02 2020-08-27 Astellas Deutschland Gmbh أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية
DE102010055499A1 (de) 2010-12-22 2011-06-16 W.C. Heraeus Gmbh Prozess zur Herstellung von Bendamustinalkylester, Bendarmustin sowie Derivaten davon

Also Published As

Publication number Publication date
PL2656843T3 (pl) 2015-08-31
DK2656843T3 (en) 2015-04-20
ES2535511T3 (es) 2015-05-12
US20130289032A1 (en) 2013-10-31
PT2656843E (pt) 2015-04-14
US8809549B2 (en) 2014-08-19
EP2656843A1 (en) 2013-10-30
EP2656843B1 (en) 2015-03-18
HRP20150436T1 (hr) 2015-05-22

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