SI2376915T1 - Metoda za diagnosticiranje mps iiib motnje - Google Patents
Metoda za diagnosticiranje mps iiib motnjeInfo
- Publication number
- SI2376915T1 SI2376915T1 SI200931646A SI200931646A SI2376915T1 SI 2376915 T1 SI2376915 T1 SI 2376915T1 SI 200931646 A SI200931646 A SI 200931646A SI 200931646 A SI200931646 A SI 200931646A SI 2376915 T1 SI2376915 T1 SI 2376915T1
- Authority
- SI
- Slovenia
- Prior art keywords
- disorder
- mps iiib
- diagnosing mps
- diagnosing
- iiib
- Prior art date
Links
- 208000025820 Sanfilippo syndrome type B Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 208000036709 mucopolysaccharidosis type 3B Diseases 0.000 title 1
- 208000012227 mucopolysaccharidosis type IIIB Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4842—Monitoring progression or stage of a disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4866—Evaluating metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
- C07H7/033—Uronic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/38—Pediatrics
- G01N2800/385—Congenital anomalies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7057—(Intracellular) signaling and trafficking pathways
- G01N2800/7066—Metabolic pathways
- G01N2800/7071—Carbohydrate metabolism, e.g. glycolysis, gluconeogenesis
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14229109P | 2009-01-02 | 2009-01-02 | |
US16436509P | 2009-03-27 | 2009-03-27 | |
US12/649,094 US9029530B2 (en) | 2009-01-02 | 2009-12-29 | Detection of oligosaccharides |
EP09837207.1A EP2376915B1 (en) | 2009-01-02 | 2009-12-31 | Method for diagnosing mps iiib disorder |
PCT/US2009/069941 WO2010078511A2 (en) | 2009-01-02 | 2009-12-31 | Detection of oligosaccharides |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2376915T1 true SI2376915T1 (sl) | 2017-07-31 |
Family
ID=41795899
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200931646A SI2376915T1 (sl) | 2009-01-02 | 2009-12-31 | Metoda za diagnosticiranje mps iiib motnje |
Country Status (13)
Country | Link |
---|---|
US (4) | US9029530B2 (sl) |
EP (2) | EP2376915B1 (sl) |
CA (2) | CA2786111C (sl) |
CY (1) | CY1118871T1 (sl) |
DK (1) | DK2376915T3 (sl) |
ES (1) | ES2623917T3 (sl) |
GB (1) | GB2468386B (sl) |
HR (1) | HRP20170578T1 (sl) |
LT (1) | LT2376915T (sl) |
PL (1) | PL2376915T3 (sl) |
PT (1) | PT2376915T (sl) |
SI (1) | SI2376915T1 (sl) |
WO (1) | WO2010078511A2 (sl) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8232073B2 (en) * | 2009-01-02 | 2012-07-31 | Zacharon Pharmaceuticals, Inc. | Quantification of non-reducing end glycan residual compounds |
US8592140B2 (en) | 2009-01-02 | 2013-11-26 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
US8809009B2 (en) | 2009-01-02 | 2014-08-19 | Biomarin Pharmaceutical Inc. | Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker |
US9029530B2 (en) | 2009-01-02 | 2015-05-12 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
WO2012016216A2 (en) * | 2010-07-29 | 2012-02-02 | Shire Human Genetic Therapies | Assays for detection of glycosaminoglycans |
EP2776553B1 (en) * | 2011-11-07 | 2018-07-11 | Shire Human Genetic Therapies, Inc. | Biomarkers for sanfilippo syndrome and uses thereof |
KR102078431B1 (ko) * | 2012-09-27 | 2020-02-17 | 바이오마린 파머수티컬 인크. | 비환원성 말단 글리칸 잔류 화합물의 정량화 |
TWI711632B (zh) | 2012-11-27 | 2020-12-01 | 美商拜奧馬林製藥公司 | 靶向治療性溶小體酶融合蛋白及其用途 |
CA2907887C (en) | 2013-03-26 | 2020-10-06 | Kunming Institute Of Botany, Chinese Academy Of Sciences | Low-molecular-weight glycosaminoglycan derivative, pharmaceutical composition thereof, preparation method therefor and use thereof |
MA40954A (fr) * | 2014-11-14 | 2017-09-19 | Shire Human Genetic Therapies | Détermination de niveaux de glycosaminoglycane par spectrométrie de masse |
WO2018183369A1 (en) * | 2017-03-27 | 2018-10-04 | Rhode Island Council On Postsecondary Education | Cranberry-derived compositions for potentiating antibiotic efficacy against bacterial persistence |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US138105A (en) * | 1873-04-22 | Improvement in seed-planters | ||
US159343A (en) * | 1875-02-02 | Improvement in stays for the bottoms of pantaloons | ||
US153752A (en) * | 1874-08-04 | Improvement in compost-distributers | ||
US5185245A (en) * | 1989-02-24 | 1993-02-09 | Thomas Jefferson University | Immumoassays and kit for detection of proteoglycans |
AUPN261895A0 (en) * | 1995-04-28 | 1995-05-18 | Australian National University, The | Preparation and use of sulfated oligosaccharides |
ATE200580T1 (de) * | 1996-08-17 | 2001-04-15 | Aventis Behring Gmbh | Verfahren zur quantifizierung von glykosaminoglykanen in antithrombin iii-haltigen lösungen |
US20050159343A1 (en) * | 1999-03-26 | 2005-07-21 | Board Of Regents, University Of Texas System | Inhibitors of glycosaminoglycans |
US6852696B2 (en) * | 1999-03-26 | 2005-02-08 | The University Of Texas System | Inhibitors of glycosaminoglycans |
AU774650B2 (en) * | 1999-03-26 | 2004-07-01 | University Of Texas System, The | Modulators of polysaccharides and uses thereof |
TR200201121T2 (tr) | 1999-10-26 | 2003-01-21 | Plant Research International B.V. | Bitkilerde memeli-tipi glikosilasyon |
AU1738301A (en) * | 1999-10-26 | 2001-05-08 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Gonadotrophins in plants |
US6936424B1 (en) | 1999-11-16 | 2005-08-30 | Matritech, Inc. | Materials and methods for detection and treatment of breast cancer |
EP1360485A2 (en) * | 2000-06-07 | 2003-11-12 | Duke University | Diagnostic methods for pompe disease and other glycogen storage diseases |
AU2003217385B2 (en) * | 2002-02-12 | 2008-09-11 | The Regents Of The University Of California | Non-invasive method for measuring rates of biosynthesis of biological molecules by label incorporation |
AU2003231220A1 (en) | 2002-04-30 | 2003-11-17 | Saint Louis University | A method for detecting lysosomal storage diseases |
AUPS293002A0 (en) * | 2002-06-14 | 2002-07-04 | Women's And Children's Hospital | Identification of oligosaccharides and their use in the diagnosis and evaluation of mucopolysaccharidoses and other related disorders |
AU2002950878A0 (en) | 2002-08-20 | 2002-09-12 | Proteome Systems Intellectual Property Pty Ltd | Method for diagnosing disorders |
US20060127950A1 (en) * | 2004-04-15 | 2006-06-15 | Massachusetts Institute Of Technology | Methods and products related to the improved analysis of carbohydrates |
US20050238536A1 (en) * | 2004-04-21 | 2005-10-27 | Striepeke Steven K | Device and method for measuring glycosaminoglycans in body fluids |
US7651847B2 (en) * | 2004-06-22 | 2010-01-26 | The Regents Of The University Of California | Methods of oligosaccharide profiling for the detection of cancer |
US7582737B2 (en) * | 2004-07-20 | 2009-09-01 | Academia Sinica | Orthogonally protected disaccharide building blocks for synthesis of heparin oligosaccharides |
US7892752B2 (en) * | 2005-04-26 | 2011-02-22 | Dwek Raymond A | Glycosylation markers for cancer diagnosing and monitoring |
FI20055417A0 (fi) | 2005-07-20 | 2005-07-20 | Glykos Finland Oy | Syöpäpesifiset glykaanit ja niiden käyttö |
JP4965999B2 (ja) * | 2005-12-27 | 2012-07-04 | セント ルイス ユニバーシティ | ムコ多糖症の診断方法 |
EP2008096A2 (en) * | 2006-04-03 | 2008-12-31 | Massachusetts Institute of Technology | Glycomic patterns for the detection of disease |
GB0610350D0 (en) | 2006-05-25 | 2006-07-05 | Univ Liverpool | prevention and/or treatment of neuodegenerative disorders |
JP2011526925A (ja) * | 2008-07-01 | 2011-10-20 | ザカロン ファーマシューティカルズ,インク. | ヘパラン硫酸阻害剤 |
US8809009B2 (en) | 2009-01-02 | 2014-08-19 | Biomarin Pharmaceutical Inc. | Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker |
US8183003B2 (en) * | 2009-01-02 | 2012-05-22 | Zacharon Pharmaceuticals, Inc. | Polymer end group detection |
US9029530B2 (en) | 2009-01-02 | 2015-05-12 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
US8232073B2 (en) * | 2009-01-02 | 2012-07-31 | Zacharon Pharmaceuticals, Inc. | Quantification of non-reducing end glycan residual compounds |
US8592140B2 (en) * | 2009-01-02 | 2013-11-26 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
US20100248365A1 (en) * | 2009-03-27 | 2010-09-30 | Zacharon Pharmaceuticals, Inc. | Ganglioside biosynthesis modulators |
US20120100609A1 (en) * | 2009-03-27 | 2012-04-26 | Crawford Brett E | N-linked glycan biosynthesis modulators |
WO2011082175A2 (en) * | 2009-12-31 | 2011-07-07 | Zacharon Pharmaceuticals, Inc. | Glycosaminoglycan inhibitors |
US20180092923A1 (en) | 2015-04-15 | 2018-04-05 | Biomarin Pharmaceutical Inc. | Methods for treating lysosomal storage disorders |
-
2009
- 2009-12-29 US US12/649,094 patent/US9029530B2/en active Active
- 2009-12-31 WO PCT/US2009/069941 patent/WO2010078511A2/en active Application Filing
- 2009-12-31 CA CA2786111A patent/CA2786111C/en active Active
- 2009-12-31 PL PL09837207T patent/PL2376915T3/pl unknown
- 2009-12-31 DK DK09837207.1T patent/DK2376915T3/en active
- 2009-12-31 EP EP09837207.1A patent/EP2376915B1/en active Active
- 2009-12-31 LT LTEP09837207.1T patent/LT2376915T/lt unknown
- 2009-12-31 PT PT98372071T patent/PT2376915T/pt unknown
- 2009-12-31 GB GB0922711A patent/GB2468386B/en active Active
- 2009-12-31 EP EP17162060.2A patent/EP3232193B1/en active Active
- 2009-12-31 CA CA3047436A patent/CA3047436A1/en not_active Abandoned
- 2009-12-31 SI SI200931646A patent/SI2376915T1/sl unknown
- 2009-12-31 ES ES09837207.1T patent/ES2623917T3/es active Active
-
2015
- 2015-05-07 US US14/706,794 patent/US9796999B2/en active Active
-
2017
- 2017-04-11 HR HRP20170578TT patent/HRP20170578T1/hr unknown
- 2017-04-25 CY CY20171100464T patent/CY1118871T1/el unknown
- 2017-09-15 US US15/705,677 patent/US10683530B2/en active Active
-
2020
- 2020-05-04 US US16/866,397 patent/US20210017570A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2786111C (en) | 2019-08-06 |
PL2376915T3 (pl) | 2017-08-31 |
GB2468386A (en) | 2010-09-08 |
CA2786111A1 (en) | 2010-07-08 |
DK2376915T3 (en) | 2017-05-08 |
US20180080059A1 (en) | 2018-03-22 |
US9796999B2 (en) | 2017-10-24 |
EP2376915B1 (en) | 2017-03-29 |
EP2376915A4 (en) | 2012-09-05 |
CA3047436A1 (en) | 2010-07-08 |
US20150307915A1 (en) | 2015-10-29 |
US10683530B2 (en) | 2020-06-16 |
ES2623917T3 (es) | 2017-07-12 |
PT2376915T (pt) | 2017-05-08 |
CY1118871T1 (el) | 2018-01-10 |
US20210017570A1 (en) | 2021-01-21 |
EP3232193B1 (en) | 2023-03-01 |
US20100184013A1 (en) | 2010-07-22 |
WO2010078511A3 (en) | 2010-10-21 |
WO2010078511A2 (en) | 2010-07-08 |
US9029530B2 (en) | 2015-05-12 |
GB2468386B (en) | 2011-10-26 |
EP3232193A3 (en) | 2017-12-13 |
GB0922711D0 (en) | 2010-02-17 |
HRP20170578T1 (hr) | 2017-08-11 |
LT2376915T (lt) | 2017-06-26 |
EP3232193A2 (en) | 2017-10-18 |
EP2376915A2 (en) | 2011-10-19 |
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