SI2373647T1 - Derivati piridazinona - Google Patents

Derivati piridazinona

Info

Publication number
SI2373647T1
SI2373647T1 SI200930433T SI200930433T SI2373647T1 SI 2373647 T1 SI2373647 T1 SI 2373647T1 SI 200930433 T SI200930433 T SI 200930433T SI 200930433 T SI200930433 T SI 200930433T SI 2373647 T1 SI2373647 T1 SI 2373647T1
Authority
SI
Slovenia
Prior art keywords
pyridazinone derivatives
pyridazinone
derivatives
Prior art date
Application number
SI200930433T
Other languages
English (en)
Inventor
Dieter Dorsch
Oliver Schadt
Frank Stieber
Andree Blaukat
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SI2373647T1 publication Critical patent/SI2373647T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
SI200930433T 2009-01-08 2009-12-10 Derivati piridazinona SI2373647T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102009004061A DE102009004061A1 (de) 2009-01-08 2009-01-08 Pyridazinonderivate
PCT/EP2009/008839 WO2010078909A1 (de) 2009-01-08 2009-12-10 Pyridazinonderivate
EP09768339A EP2373647B1 (de) 2009-01-08 2009-12-10 Pyridazinonderivate

Publications (1)

Publication Number Publication Date
SI2373647T1 true SI2373647T1 (sl) 2013-01-31

Family

ID=41581157

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200930433T SI2373647T1 (sl) 2009-01-08 2009-12-10 Derivati piridazinona

Country Status (24)

Country Link
US (1) US8623870B2 (sl)
EP (1) EP2373647B1 (sl)
JP (1) JP5683488B2 (sl)
KR (1) KR101669696B1 (sl)
CN (1) CN102272131A (sl)
AR (1) AR074997A1 (sl)
AU (1) AU2009336851B2 (sl)
BR (1) BRPI0923903B8 (sl)
CA (1) CA2749015C (sl)
CY (1) CY1113700T1 (sl)
DE (1) DE102009004061A1 (sl)
DK (1) DK2373647T3 (sl)
EA (1) EA020574B1 (sl)
ES (1) ES2398023T3 (sl)
HR (1) HRP20120976T1 (sl)
IL (1) IL213826A (sl)
MX (1) MX2011007209A (sl)
PL (1) PL2373647T3 (sl)
PT (1) PT2373647E (sl)
SG (1) SG172458A1 (sl)
SI (1) SI2373647T1 (sl)
SM (1) SMT201300010B (sl)
WO (1) WO2010078909A1 (sl)
ZA (1) ZA201105781B (sl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5795964A (en) 1980-12-04 1982-06-15 Morishita Seiyaku Kk Preparation of 2-substituted-3(2h)-pyridazinone derivative
US4397854A (en) 1981-05-14 1983-08-09 Warner-Lambert Company Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
AU691673B2 (en) 1994-11-14 1998-05-21 Dow Agrosciences Llc Pyridazinones and their use as fungicides
US5635494A (en) 1995-04-21 1997-06-03 Rohm And Haas Company Dihydropyridazinones and pyridazinones and their use as fungicides and insecticides
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
TR199801530T2 (xx) 1996-02-13 1998-11-23 Zeneca Limited VEGF �nhibit�rleri olarak kinazolin t�revleri.
JP4464466B2 (ja) 1996-03-05 2010-05-19 アストラゼネカ・ユーケイ・リミテッド 4―アニリノキナゾリン誘導体
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
WO1999025697A1 (fr) 1997-11-19 1999-05-27 Kowa Co., Ltd. Nouveaux derives de pyridazine et medicaments contenant ces composes comme principe actif
TWI241295B (en) 1998-03-02 2005-10-11 Kowa Co Pyridazine derivative and medicine containing the same as effect component
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
WO2001092224A1 (en) 2000-05-31 2001-12-06 Astrazeneca Ab Indole derivatives with vascular damaging activity
IL153484A0 (en) 2000-07-07 2003-07-06 Angiogene Pharm Ltd Colchinol derivatives as angiogenesis inhibitors
BR0112225A (pt) 2000-07-07 2003-05-06 Angiogene Pharm Ltd Composto, composição farmacêutica, uso de um composto, e, processo papa preparar um composto
EP1463509A1 (en) 2001-10-31 2004-10-06 MERCK PATENT GmbH Type 4 phosphodiesterase inhibitors and uses thereof
RU2004117082A (ru) 2001-12-05 2005-04-10 Орто-Макнейл Фармасьютикал, Инк. (Us) Кетолидные 6-0-ацил-производные эритромицина в качестве антибактериальных средств
WO2005121132A1 (ja) 2004-06-11 2005-12-22 Shionogi & Co., Ltd. 抗hcv作用を有する縮合ヘテロ環化合物
DE102005057924A1 (de) 2005-12-05 2007-06-06 Merck Patent Gmbh Pyridazinonderivate
EP1959955B1 (en) 2005-12-05 2010-11-17 Pfizer Products Inc. Method of treating abnormal cell growth
DE102006037478A1 (de) 2006-08-10 2008-02-14 Merck Patent Gmbh 2-(Heterocyclylbenzyl)-pyridazinonderivate
TW200845991A (en) * 2007-01-12 2008-12-01 Smithkline Beecham Corp N-substituted glycine derivatives: hydroxylase inhibitors
DE102007061963A1 (de) * 2007-12-21 2009-06-25 Merck Patent Gmbh Pyridazinonderivate
WO2010075068A1 (en) * 2008-12-16 2010-07-01 Schering Corporation Pyridopyrimidine derivatives and methods of use thereof
DE102009003954A1 (de) * 2009-01-07 2010-07-08 Merck Patent Gmbh Pyridazinonderivate

Also Published As

Publication number Publication date
AU2009336851B2 (en) 2016-03-03
AR074997A1 (es) 2011-03-02
EA020574B1 (ru) 2014-12-30
CN102272131A (zh) 2011-12-07
ES2398023T3 (es) 2013-03-13
SG172458A1 (en) 2011-08-29
US20110269771A1 (en) 2011-11-03
US8623870B2 (en) 2014-01-07
EA201101038A1 (ru) 2012-01-30
CA2749015C (en) 2017-10-31
HRP20120976T1 (hr) 2012-12-31
DK2373647T3 (da) 2012-12-10
ZA201105781B (en) 2012-04-25
EP2373647A1 (de) 2011-10-12
CA2749015A1 (en) 2010-07-15
JP2012514612A (ja) 2012-06-28
IL213826A0 (en) 2011-07-31
BRPI0923903B1 (pt) 2020-03-24
AU2009336851A1 (en) 2011-08-25
PT2373647E (pt) 2013-01-30
JP5683488B2 (ja) 2015-03-11
PL2373647T3 (pl) 2013-03-29
KR20110099799A (ko) 2011-09-08
BRPI0923903A2 (pt) 2015-07-28
MX2011007209A (es) 2011-08-04
DE102009004061A1 (de) 2010-07-15
EP2373647B1 (de) 2012-10-31
KR101669696B1 (ko) 2016-10-27
SMT201300010B (it) 2013-03-08
BRPI0923903B8 (pt) 2021-05-25
IL213826A (en) 2016-07-31
CY1113700T1 (el) 2016-06-22
WO2010078909A1 (de) 2010-07-15

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