SI2234617T1 - Dosing regimen associated with long acting injectable paliperidone esters - Google Patents

Dosing regimen associated with long acting injectable paliperidone esters

Info

Publication number
SI2234617T1
SI2234617T1 SI200832163T SI200832163T SI2234617T1 SI 2234617 T1 SI2234617 T1 SI 2234617T1 SI 200832163 T SI200832163 T SI 200832163T SI 200832163 T SI200832163 T SI 200832163T SI 2234617 T1 SI2234617 T1 SI 2234617T1
Authority
SI
Slovenia
Prior art keywords
dosing regimen
long acting
acting injectable
regimen associated
injectable paliperidone
Prior art date
Application number
SI200832163T
Other languages
Slovenian (sl)
Inventor
An Margriet Cornelia Vermeulen
Alfons Jeanne Wouters
Srihari Gopal
Vivek Kusamaker
Peter H. Lewyn-Briscoe
Mahesh Samtani
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40428256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2234617(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SI2234617T1 publication Critical patent/SI2234617T1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01LSEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L21/00Processes or apparatus adapted for the manufacture or treatment of semiconductor or solid state devices or of parts thereof
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01LSEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L31/00Semiconductor devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation and specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation; Processes or apparatus specially adapted for the manufacture or treatment thereof or of parts thereof; Details thereof
    • H01L31/08Semiconductor devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation and specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation; Processes or apparatus specially adapted for the manufacture or treatment thereof or of parts thereof; Details thereof in which radiation controls flow of current through the device, e.g. photoresistors
    • H01L31/10Semiconductor devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation and specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation; Processes or apparatus specially adapted for the manufacture or treatment thereof or of parts thereof; Details thereof in which radiation controls flow of current through the device, e.g. photoresistors characterised by at least one potential-jump barrier or surface barrier, e.g. phototransistors
    • H01L31/101Devices sensitive to infrared, visible or ultraviolet radiation
    • H01L31/102Devices sensitive to infrared, visible or ultraviolet radiation characterised by only one potential barrier or surface barrier
    • H01L31/109Devices sensitive to infrared, visible or ultraviolet radiation characterised by only one potential barrier or surface barrier the potential barrier being of the PN heterojunction type
SI200832163T 2007-12-19 2008-12-17 Dosing regimen associated with long acting injectable paliperidone esters SI2234617T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1491807P 2007-12-19 2007-12-19
US12027608P 2008-12-05 2008-12-05
PCT/EP2008/067738 WO2009080651A1 (en) 2007-12-19 2008-12-17 Dosing regimen associated with long acting injectable paliperidone esters
EP08863534.7A EP2234617B1 (en) 2007-12-19 2008-12-17 Dosing regimen associated with long acting injectable paliperidone esters

Publications (1)

Publication Number Publication Date
SI2234617T1 true SI2234617T1 (en) 2021-07-30

Family

ID=40428256

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200832163T SI2234617T1 (en) 2007-12-19 2008-12-17 Dosing regimen associated with long acting injectable paliperidone esters

Country Status (26)

Country Link
US (3) US9439906B2 (en)
EP (2) EP2234617B1 (en)
JP (1) JP5825786B2 (en)
KR (3) KR20100099292A (en)
CN (2) CN105560176A (en)
AU (2) AU2008340101B2 (en)
BR (1) BRPI0821408A2 (en)
CO (1) CO6300949A2 (en)
CY (1) CY1124103T1 (en)
DK (1) DK2234617T3 (en)
EA (1) EA020697B1 (en)
EC (1) ECSP10010289A (en)
ES (1) ES2868353T3 (en)
GT (1) GT201000182A (en)
HK (1) HK1223850A1 (en)
HR (1) HRP20210669T1 (en)
HU (1) HUE053904T2 (en)
IL (2) IL206448A (en)
LT (1) LT2234617T (en)
NI (1) NI201000105A (en)
NZ (1) NZ586221A (en)
PL (1) PL2234617T3 (en)
PT (1) PT2234617T (en)
RS (1) RS61765B1 (en)
SI (1) SI2234617T1 (en)
WO (1) WO2009080651A1 (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA72189C2 (en) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Aqueous suspensions of 9-hydroxy-risperidone fatty acid esters provided in submicron form
KR20100099292A (en) 2007-12-19 2010-09-10 얀센 파마슈티카 엔.브이. Dosing regimen associated with long acting injectable paliperidone esters
EP2485712A1 (en) 2009-10-06 2012-08-15 Ascendis Pharma A/S Subcutaneous paliperidone composition
EP2485767A1 (en) 2009-10-06 2012-08-15 Ascendis Pharma A/S Carrier linked paliperidone prodrugs
EP2493473A1 (en) * 2009-10-30 2012-09-05 Janssen Pharmaceutica NV Dosing regimen associated with long-acting injectable paliperidone esters
US9271939B2 (en) 2010-03-15 2016-03-01 Inventia Healthcare Private Limited Stabilized prolonged release pharmaceutical composition comprising atypical antipsychotic
US9522980B2 (en) 2010-05-06 2016-12-20 Johnson & Johnson Vision Care, Inc. Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same
EP2529756B1 (en) 2011-05-31 2021-05-19 Laboratorios Farmaceuticos Rovi, S.A. Risperidone and/or Paliperidone implant formulation
TWI577377B (en) * 2010-09-16 2017-04-11 Viiv醫療保健公司 Pharmaceutical compositions
CA2830511C (en) * 2011-03-18 2021-09-14 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising aripiprazole lauroxil and sorbitan laurate
US9170349B2 (en) 2011-05-04 2015-10-27 Johnson & Johnson Vision Care, Inc. Medical devices having homogeneous charge density and methods for making same
PL2529757T3 (en) 2011-05-31 2014-04-30 Farm Rovi Lab Sa Paliperidone implant formulation
CN102274164B (en) * 2011-08-22 2014-07-02 长春健欣生物医药科技开发有限公司 Sustained release gel for injection for paliperidone and paliperidone derivative
CN103301461B (en) * 2012-03-08 2018-09-07 江苏豪森药业集团有限公司 A kind of long acting injection and its preparation method and application
US9999670B2 (en) 2012-03-19 2018-06-19 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising benzyl alcohol
CA2867121C (en) 2012-03-19 2021-05-25 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising fatty acid esters
US9993556B2 (en) 2012-03-19 2018-06-12 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising fatty glycerol esters
US9244196B2 (en) 2012-05-25 2016-01-26 Johnson & Johnson Vision Care, Inc. Polymers and nanogel materials and methods for making and using the same
US10073192B2 (en) 2012-05-25 2018-09-11 Johnson & Johnson Vision Care, Inc. Polymers and nanogel materials and methods for making and using the same
EP3718536A1 (en) 2012-09-19 2020-10-07 Alkermes Pharma Ireland Limited Pharmaceutical compositions having improved storage stability
MA39495A (en) 2014-03-20 2015-09-24 Alkermes Pharma Ireland Ltd ARIIPIPRAZOLE FORMULATIONS WITH HIGHER INJECTION RATES
LT3185867T (en) 2014-08-25 2021-06-10 Alkermes Pharma Ireland Limited Crystallization process of aripiprazole derivatives in extended release formulations for treatment of schizophrenia
US9844551B2 (en) 2015-01-14 2017-12-19 Children's Hospital Medical Center Compositions and methods for treatment of fragile X syndrome
JP6885649B2 (en) * 2015-02-17 2021-06-16 バンダ・ファーマシューティカルズ・インコーポレイテッドVanda Pharmaceuticals Inc. Iroperidon for the treatment of schizophrenia
WO2016157061A1 (en) 2015-03-31 2016-10-06 Wockhardt Limited Aseptic wet milling process for paliperidone palmitate
MA41917B1 (en) * 2015-04-07 2020-07-29 Janssen Pharmaceuticals Inc Missed Dose Treatment Schedule for Long-Acting Injectable Paliperidone Esters
US20190321367A1 (en) * 2016-11-23 2019-10-24 Children's Hospital Medical Center Paliperidone for treatment of drug refractory irritability and autism spectrum disorder
JP7337080B2 (en) * 2017-10-27 2023-09-01 嘉奥制薬(石家庄)有限公司 Dosing Regimens for Paliperidone Palmitate Sustained Release Suspension Injection
EP3761983A1 (en) 2018-03-05 2021-01-13 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
CN110279659A (en) * 2019-07-08 2019-09-27 华裕(无锡)制药有限公司 Palmitinic acid 9-hydroxy-risperidone preparation and preparation method thereof
GR1009869B (en) * 2019-07-12 2020-11-12 Φαρματεν Α.Β.Ε.Ε. Long acting injectable pgarmaceutical composition comprising paliperidone palmitate and method of preparation thereof
WO2022006336A1 (en) * 2020-07-01 2022-01-06 Jubilant Pharma Holdings Inc. Long-acting injection dosage form of beta 3 adrenoreceptor agonists
TW202222317A (en) 2020-11-30 2022-06-16 比利時商健生藥品公司 Dosing regimens associated with extended release paliperidone injectable formulations
AU2021388842A1 (en) 2020-11-30 2023-07-13 Janssen Pharmaceutica Nv Methods for ensuring resuspension of paliperidone palmitate formulations
CN116583270A (en) 2020-11-30 2023-08-11 詹森药业有限公司 Dosing regimen associated with extended release paliperidone injectable formulations
DK4025187T3 (en) 2020-11-30 2024-03-04 Janssen Pharmaceutica Nv DOSAGE REGIMES ASSOCIATED WITH EXTENDED-RELEASE INJECTABLE PALIPERIDONE FORMULATIONS
RU2756614C1 (en) * 2021-04-07 2021-10-04 Федеральное государственное бюджетное научное учреждение «Томский национальный исследовательский медицинский центр Российской академии наук» (Томский НИМЦ) Method for supporting medical decisions on selection of antipsychotic therapy in patients with schizophrenia in order to prevent akathisia
IL310909A (en) 2021-08-20 2024-04-01 Janssen Pharmaceutica Nv Dosing regimens associated with extended release paliperidone injectable formulations

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1491807A (en) 1922-06-20 1924-04-29 John P Mclinn Traveling bag
US1491809A (en) 1923-02-17 1924-04-29 Us Fireworks Mfg Company Inc Toy
US4804663A (en) 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
US5254556A (en) 1988-11-07 1993-10-19 Janssen Pharmaceutica N.V. 3-piperidinyl-1,2-benzisoxazoles
US5158952A (en) 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
TW376319B (en) 1993-04-28 1999-12-11 Janssen Pharmaceutica Nv Pharmaceutical composition containing risperidone pamoate and having a long acting activity for treating psychoses induced by the release of dopamine
US5453425A (en) 1994-07-11 1995-09-26 Janssen Pharmaceutica N.V. Risperidone oral formulation
TW487572B (en) 1996-05-20 2002-05-21 Janssen Pharmaceutica Nv Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters
UA72189C2 (en) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Aqueous suspensions of 9-hydroxy-risperidone fatty acid esters provided in submicron form
US6342488B1 (en) 1998-08-18 2002-01-29 Sepracor, Inc. Phosphonorisperidone and sulforisperidone compositions and methods
KR100338776B1 (en) 2000-07-11 2002-05-31 윤종용 Semiconductor memory device capable of multi row address testing and method thereof
ATE373472T1 (en) * 2002-07-29 2007-10-15 Alza Corp METHOD AND DOSAGE FORMS FOR THE CONTROLLED DELIVERY OF PALIPERIDONE
ATE345277T1 (en) 2002-08-21 2006-12-15 Pharmacia Corp INJECTABLE PHARMACEUTICAL SUSPENSION IN A TWO-CHAMBER VIAL
US20060079846A1 (en) 2004-10-08 2006-04-13 Alton Williams Hypodermic syringes with multiple needles and methods of calming psychiatric patients using such
JP5249748B2 (en) * 2005-04-25 2013-07-31 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Sterile 3- [2- [4- (6-Fluoro-1,2-benzisoxazol-3-yl) -1-piperidinyl] ethyl] -6,7,8,9-tetrahydro-9-hydroxy-2- Preparation of methyl-4H-pyrido [1,2-a] pyrimidin-4-onepalmitate
US20070197591A1 (en) * 2005-12-12 2007-08-23 Sandra Boom Use of paliperidone for the treatment of a mental disorder in a psychiatric patient with reduced hepatic function
US20070232624A1 (en) * 2006-04-03 2007-10-04 Palumbo Joseph M Use of paliperidone for the treatment of sleep disturbances and/or excessive daytime sleepiness in psychiatric patients
US20080177067A1 (en) 2006-08-14 2008-07-24 Ben-Zion Dolitzky Crystal forms of 9-hydroxy-risperidone (paliperidone)
WO2009025859A1 (en) 2007-08-21 2009-02-26 Teva Pharmaceutical Industries Ltd. Paliperidone sustained release formulation
NZ584370A (en) 2007-10-09 2011-04-29 Cipla Ltd Processes for the preparation of paliperidone and pharmaceutically acceptable salts thereof and intermediates for use in the processes
KR20100099292A (en) 2007-12-19 2010-09-10 얀센 파마슈티카 엔.브이. Dosing regimen associated with long acting injectable paliperidone esters
EP2493473A1 (en) 2009-10-30 2012-09-05 Janssen Pharmaceutica NV Dosing regimen associated with long-acting injectable paliperidone esters

Also Published As

Publication number Publication date
HRP20210669T1 (en) 2021-10-29
ECSP10010289A (en) 2010-07-30
CN105560176A (en) 2016-05-11
US20090163519A1 (en) 2009-06-25
EP3909585A1 (en) 2021-11-17
EP2234617B1 (en) 2021-03-31
US20180147210A1 (en) 2018-05-31
RS61765B1 (en) 2021-05-31
AU2015200801B2 (en) 2016-12-15
JP2011506555A (en) 2011-03-03
PL2234617T3 (en) 2021-11-08
AU2015200801A1 (en) 2015-03-12
KR20190049933A (en) 2019-05-09
ES2868353T3 (en) 2021-10-21
BRPI0821408A2 (en) 2015-06-16
KR102318070B1 (en) 2021-10-27
CY1124103T1 (en) 2022-05-27
NI201000105A (en) 2011-03-17
KR20170018489A (en) 2017-02-17
EA201070757A1 (en) 2011-02-28
IL206448A (en) 2017-12-31
AU2008340101B2 (en) 2015-02-19
NZ586221A (en) 2012-08-31
DK2234617T3 (en) 2021-05-25
HK1223850A1 (en) 2017-08-11
GT201000182A (en) 2012-03-26
EP2234617A1 (en) 2010-10-06
EA020697B1 (en) 2015-01-30
AU2008340101A1 (en) 2009-07-02
HUE053904T2 (en) 2021-07-28
LT2234617T (en) 2021-05-25
CN101932327A (en) 2010-12-29
JP5825786B2 (en) 2015-12-02
US20170128451A1 (en) 2017-05-11
US9439906B2 (en) 2016-09-13
IL253468A0 (en) 2017-09-28
KR20100099292A (en) 2010-09-10
IL206448A0 (en) 2010-12-30
CO6300949A2 (en) 2011-07-21
PT2234617T (en) 2021-05-18
KR102163196B1 (en) 2020-10-12
WO2009080651A1 (en) 2009-07-02

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