SI1891446T1 - Postopek za identifikacijo novih spojin, ki vstopajo v interakcijo z encimi - Google Patents

Postopek za identifikacijo novih spojin, ki vstopajo v interakcijo z encimi

Info

Publication number
SI1891446T1
SI1891446T1 SI200631589T SI200631589T SI1891446T1 SI 1891446 T1 SI1891446 T1 SI 1891446T1 SI 200631589 T SI200631589 T SI 200631589T SI 200631589 T SI200631589 T SI 200631589T SI 1891446 T1 SI1891446 T1 SI 1891446T1
Authority
SI
Slovenia
Prior art keywords
identification
novel enzyme
interacting compounds
enzyme interacting
compounds
Prior art date
Application number
SI200631589T
Other languages
English (en)
Inventor
Gerard Drewes
Bernhard Kuester
Ulrich Kruse
Carsten Hopf
Dirk Eberhard
Marcus Bantscheff
Valerie Reader
David Middlemiss
Manfred Raida
Original Assignee
Cellzome Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellzome Gmbh filed Critical Cellzome Gmbh
Priority claimed from PCT/EP2006/062984 external-priority patent/WO2006134056A1/en
Publication of SI1891446T1 publication Critical patent/SI1891446T1/sl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
SI200631589T 2005-06-14 2006-06-07 Postopek za identifikacijo novih spojin, ki vstopajo v interakcijo z encimi SI1891446T1 (sl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP05012722A EP1734367A1 (en) 2005-06-14 2005-06-14 Process for the identification of novel enzyme interacting compounds
US71139905P 2005-08-25 2005-08-25
US78217006P 2006-03-14 2006-03-14
PCT/EP2006/062984 WO2006134056A1 (en) 2005-06-14 2006-06-07 Process for the identification of novel enzyme interacting compounds
EP06763568.0A EP1891446B1 (en) 2005-06-14 2006-06-07 Process for the identification of novel enzyme interacting compounds

Publications (1)

Publication Number Publication Date
SI1891446T1 true SI1891446T1 (sl) 2013-07-31

Family

ID=34937423

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200631589T SI1891446T1 (sl) 2005-06-14 2006-06-07 Postopek za identifikacijo novih spojin, ki vstopajo v interakcijo z encimi

Country Status (8)

Country Link
EP (3) EP1734367A1 (sl)
JP (1) JP4932835B2 (sl)
CN (1) CN101223447A (sl)
DE (1) DE6763568T1 (sl)
DK (1) DK1891446T3 (sl)
ES (1) ES2412380T3 (sl)
PT (1) PT1891446E (sl)
SI (1) SI1891446T1 (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101965408B (zh) * 2008-02-04 2013-08-28 塞尔卓姆有限责任公司 针对多重靶的pi3k相互作用分子的选择性概况分析
CN102027371A (zh) * 2008-05-16 2011-04-20 塞尔卓姆股份公司 Parp相互作用分子的鉴定方法和parp蛋白的纯化方法
EP2124060A1 (en) * 2008-05-23 2009-11-25 ETH Zurich Method for high throughput peptide/protein assay generation and assays generated therewith
WO2010070394A1 (en) * 2008-12-17 2010-06-24 Universite Pierre Et Marie Curie-Paris Vi Modulators of the cx3cr1 receptor and therapeutic uses thereof
CA2785534C (en) * 2009-12-22 2019-07-30 Expression Pathology, Inc. Epidermal growth factor receptor (egfr) protein srm/mrm assay
WO2017206041A1 (zh) * 2016-05-31 2017-12-07 王帅 测定细胞内配体靶蛋白相互作用持久力的方法
CN113945670A (zh) * 2021-09-30 2022-01-18 上海中科新生命生物科技有限公司 一种基于化学蛋白质组学的激酶富集检测方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9119240D0 (en) * 1991-09-09 1991-10-23 Avalon Biosciences Ltd Enzyme capture assay for human secretory acetyl cholinesterase
IL106106A0 (en) * 1993-06-22 1993-10-20 Interpharm Lab Ltd Library of polymeric molecules and its preparation
US5536822A (en) 1994-03-09 1996-07-16 University Of Virginia Alumni Patents Foundation γ-phosphate linked adenosine 5' triphosphate sepharose
US6428956B1 (en) * 1998-03-02 2002-08-06 Isis Pharmaceuticals, Inc. Mass spectrometric methods for biomolecular screening
CA2369868A1 (en) 1999-04-15 2000-10-26 The University Of Virginia Patent Foundation Proteome mining
WO2001077684A2 (en) 2000-04-10 2001-10-18 The Scripps Research Institute Proteomic analysis using activity-based probe libraries
US20030143648A1 (en) 2001-11-29 2003-07-31 Cravatt Benjamin F. Enzyme activity profiles
US20030186221A1 (en) 2002-04-02 2003-10-02 Lockhart David J. Phage display affinity filter and forward screen
WO2003088990A1 (en) * 2002-04-15 2003-10-30 American National Red Cross Plasma protein-binding ligands
EP1521841B1 (en) * 2002-07-11 2010-04-14 The American National Red Cross Method for identifying individual active entities from complex mixtures
US20060105445A1 (en) * 2002-07-29 2006-05-18 Klaus Godl Medium and method for enriching, purifying or depleting atp binding proteins from a pool of proteins

Also Published As

Publication number Publication date
CN101223447A (zh) 2008-07-16
EP2613153A3 (en) 2014-05-21
DK1891446T3 (da) 2013-06-17
EP2613154A2 (en) 2013-07-10
ES2412380T3 (es) 2013-07-11
EP1734367A1 (en) 2006-12-20
EP2613153A2 (en) 2013-07-10
PT1891446E (pt) 2013-06-12
JP2008543296A (ja) 2008-12-04
JP4932835B2 (ja) 2012-05-16
EP2613154A3 (en) 2013-07-17
DE6763568T1 (de) 2011-09-22

Similar Documents

Publication Publication Date Title
HK1115631A1 (en) Process for the identification of novel enzyme interacting compounds
HK1220208A1 (zh) 用於酶抑制的化合物
EP1893570A4 (en) IMPROVED PROCESS FOR THE PREPARATION OF EZETIMIBE
PL1743882T3 (pl) Sposób do produkcji izocyjanianów
IL185419A0 (en) Improved process for the synthesis of enantiomeric indanylamine derivatives
SI2292607T1 (sl) Postopek za sintezo organskih spojin
EP1861408A4 (en) PROCESS FOR PRODUCING HYDROCHLOROSILANES
EP1940793A4 (en) METHOD FOR PRODUCING MONTELUCASTS
EP1874948A4 (en) PROCESS FOR THE PREPARATION OF Y-GLUTAMYLCYSTEIN
ZA200804264B (en) Process for the preparation of ferri-succinylcasein
PL1807395T3 (pl) Sposób syntezy n-alkoksyamin
GB0500604D0 (en) Novel process
SI1891446T1 (sl) Postopek za identifikacijo novih spojin, ki vstopajo v interakcijo z encimi
GB0519758D0 (en) Novel process
IL184715A0 (en) Process for the preparation of intermediates
ZA200601910B (en) Process for the preparation of organosilances
IL187155A0 (en) Process for production of 4-biphenylazetidin-2-ones
GB0526474D0 (en) Novel process
ZA200710066B (en) Process for production of 4-biphenylylazetidin-2-ones
GB0501253D0 (en) Process for the production of olefins
ZA200709621B (en) Process for the synthesis of organic compounds
IL185076A0 (en) Process for the prepartion of enantiomerically pure 1-substituted-3-aminoalcohols
HUP0500570A3 (en) Process for the preparation of (s)-(-)-amlodipine
GB0518290D0 (en) Novel process
GB0518287D0 (en) Novel process