SI1848458T1 - Uporaba aktiviranega polimera za ločevanje proteina in polipeptidnih multimerov - Google Patents
Uporaba aktiviranega polimera za ločevanje proteina in polipeptidnih multimerovInfo
- Publication number
- SI1848458T1 SI1848458T1 SI200630466T SI200630466T SI1848458T1 SI 1848458 T1 SI1848458 T1 SI 1848458T1 SI 200630466 T SI200630466 T SI 200630466T SI 200630466 T SI200630466 T SI 200630466T SI 1848458 T1 SI1848458 T1 SI 1848458T1
- Authority
- SI
- Slovenia
- Prior art keywords
- protein
- separation
- activated polymers
- polypeptide multimers
- polypeptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05003332 | 2005-02-16 | ||
| EP06706962A EP1848458B1 (en) | 2005-02-16 | 2006-02-15 | Use of activated polymers for separation of protein and polypeptide multimers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1848458T1 true SI1848458T1 (sl) | 2010-01-29 |
Family
ID=36168573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200630466T SI1848458T1 (sl) | 2005-02-16 | 2006-02-15 | Uporaba aktiviranega polimera za ločevanje proteina in polipeptidnih multimerov |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080312411A1 (sl) |
| EP (1) | EP1848458B1 (sl) |
| JP (1) | JP2008530163A (sl) |
| AT (1) | ATE447414T1 (sl) |
| AU (2) | AU2006215823A1 (sl) |
| CA (1) | CA2594666A1 (sl) |
| DE (1) | DE602006010176D1 (sl) |
| DK (1) | DK1848458T3 (sl) |
| ES (1) | ES2335304T3 (sl) |
| HR (1) | HRP20090594T1 (sl) |
| SI (1) | SI1848458T1 (sl) |
| WO (1) | WO2006087178A1 (sl) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2331139B1 (en) * | 2008-09-11 | 2019-04-17 | Nektar Therapeutics | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method |
| US9315514B2 (en) | 2012-08-27 | 2016-04-19 | Rhodes Technologies | 1,3-dioxanomorphides and 1,3-dioxanocodides |
| JP6141444B2 (ja) | 2012-12-14 | 2017-06-07 | パーデュー、ファーマ、リミテッド、パートナーシップ | スピロ環式モルフィナンおよびこれらの使用 |
| CA2894971C (en) | 2012-12-14 | 2018-06-26 | Purdue Pharma L.P. | Nitrogen containing morphinan derivatives and the use thereof |
| EP2931724B1 (en) | 2012-12-14 | 2017-01-25 | Purdue Pharma LP | Pyridonemorphinan analogs and biological activity on opioid receptors |
| JP6159416B2 (ja) | 2012-12-28 | 2017-07-05 | パーデュー、ファーマ、リミテッド、パートナーシップ | ７，８−環式モルフィナン類似体 |
| EP2941431B1 (en) | 2012-12-28 | 2017-10-25 | Purdue Pharma L.P. | Substituted morphinans and the use thereof |
| ES2748803T3 (es) | 2012-12-31 | 2020-03-18 | Rhodes Tech | Procedimiento para preparar 6,14-etenomorfinanos sustituidos en 7, 6,14-etanomorfinanos sustituidos en 7 |
| WO2015097546A1 (en) | 2013-12-26 | 2015-07-02 | Purdue Pharma L.P. | Propellane-based compounds and their use as opioid receptor modulators |
| EP3087078B1 (en) | 2013-12-26 | 2019-05-15 | Purdue Pharma LP | 7-beta-alkyl analogs of orvinols |
| EP3087073B1 (en) | 2013-12-26 | 2018-07-04 | Purdue Pharma LP | 10-substituted morphinan hydantoins |
| WO2015097545A1 (en) | 2013-12-26 | 2015-07-02 | Purdue Pharma L.P. | Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans |
| EP3089978B1 (en) | 2013-12-30 | 2018-08-29 | Purdue Pharma L.P. | Pyridone-sulfone morphinan analogs as opioid receptor ligands |
| US11124505B2 (en) | 2016-12-23 | 2021-09-21 | Minoryx Therapeutics S.L. | Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione and salts thereof |
| US11845759B2 (en) | 2018-02-23 | 2023-12-19 | Rhodes Technologies | Opioid compounds and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5312808A (en) * | 1989-11-22 | 1994-05-17 | Enzon, Inc. | Fractionation of polyalkylene oxide-conjugated hemoglobin solutions |
| ES2367891T3 (es) * | 2000-09-29 | 2011-11-10 | Schering Corporation | Interleucina-10 pegilada. |
| KR20040069980A (ko) * | 2001-06-22 | 2004-08-06 | 파마시아 코포레이션 | 화학적으로 변형된 프로게니포이에틴 접합체 |
-
2006
- 2006-02-15 WO PCT/EP2006/001359 patent/WO2006087178A1/en active Application Filing
- 2006-02-15 US US11/884,300 patent/US20080312411A1/en not_active Abandoned
- 2006-02-15 DK DK06706962.5T patent/DK1848458T3/da active
- 2006-02-15 EP EP06706962A patent/EP1848458B1/en active Active
- 2006-02-15 AT AT06706962T patent/ATE447414T1/de active
- 2006-02-15 JP JP2007555522A patent/JP2008530163A/ja not_active Withdrawn
- 2006-02-15 DE DE602006010176T patent/DE602006010176D1/de active Active
- 2006-02-15 CA CA002594666A patent/CA2594666A1/en not_active Abandoned
- 2006-02-15 AU AU2006215823A patent/AU2006215823A1/en not_active Abandoned
- 2006-02-15 ES ES06706962T patent/ES2335304T3/es active Active
- 2006-02-15 SI SI200630466T patent/SI1848458T1/sl unknown
-
2007
- 2007-11-27 AU AU2007237199A patent/AU2007237199A1/en not_active Withdrawn
-
2009
- 2009-11-04 HR HR20090594T patent/HRP20090594T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008530163A (ja) | 2008-08-07 |
| HRP20090594T1 (hr) | 2009-12-31 |
| WO2006087178A1 (en) | 2006-08-24 |
| ATE447414T1 (de) | 2009-11-15 |
| US20080312411A1 (en) | 2008-12-18 |
| AU2007237199A1 (en) | 2008-01-17 |
| EP1848458A1 (en) | 2007-10-31 |
| CA2594666A1 (en) | 2006-08-24 |
| DE602006010176D1 (de) | 2009-12-17 |
| EP1848458B1 (en) | 2009-11-04 |
| ES2335304T3 (es) | 2010-03-24 |
| AU2006215823A1 (en) | 2006-08-24 |
| DK1848458T3 (da) | 2010-02-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI1848458T1 (sl) | Uporaba aktiviranega polimera za ločevanje proteina in polipeptidnih multimerov | |
| WO2007104062A3 (en) | Compositions and methods based on peptide binding profiling | |
| WO2012142515A3 (en) | Fc fusion proteins comprising novel linkers or arrangements | |
| WO2008033408A3 (en) | Methods for identifying compounds that modulate cell signaling and methods employing such compounds | |
| ES2322882B1 (es) | Peptidos inhibidores de la exocitosis neuronal. | |
| EP2617431A3 (en) | Polypeptide inhibitors of HSP27 kinase and uses therefor | |
| WO2011047087A3 (en) | Protein detection via nanoreporters | |
| WO2014026136A3 (en) | Protease-resistant systems for polypeptide display and methods of making and using thereof | |
| EA200900781A1 (ru) | 4-фенилпиран-3,5-дионы, 4-фенилтиопиран-3,5-дионы и циклогексантрионы, как новые гербициды | |
| WO2008157378A3 (en) | Rage fusion proteins | |
| CL2007003303A1 (es) | Molecula de enlace para la proteina lingo-1; polinucleotido que la codifica; vector y celula que lo comprenden; composicion farmaceutica que comprende la molecula de enlace; y su uso para el tratamiento de lesiones del sistema nervioso central. | |
| PL1909602T3 (pl) | Systemy i metody stosowane do oddzielania białek od tkanki łącznej | |
| DE602006011229D1 (de) | System zur Stromsymmetrierung | |
| EA200801180A1 (ru) | Селективные пептидные агонисты рецептора vpac2 | |
| CY1115437T1 (el) | Υδροξυμεθυλοκυκλοεξυλαμινες | |
| AU2009312751A8 (en) | A screening assay for insecticides | |
| DE602006011497D1 (de) | Empfang von an mehrere einrichtungen adressiertem audiovisuellem inhalt | |
| CA2705357C (en) | Formulations for taci-immunoglobulin fusion proteins | |
| IL223077A0 (en) | Novel as160-like protein, test systems, methods and uses involving it for the identification of diabetes type 2 therapeutics | |
| WO2008002820A3 (en) | Substituted benzyl amine compounds | |
| WO2007101146A3 (en) | Selective vpac2 receptor peptide agonists | |
| WO2007133828A3 (en) | Selective vpac2 receptor peptide agonists | |
| CY1114618T1 (el) | Βιολογικα δραστικα πεπτιδια που περιεχουν καρβοξυτελικη αργινινη | |
| WO2009005718A8 (en) | Polypeptide microparticles having sustained release characteristics, methods and uses | |
| EP2101804B8 (en) | Pro-angiogenic peptides |