SI1848458T1 - Uporaba aktiviranega polimera za ločevanje proteina in polipeptidnih multimerov - Google Patents
Uporaba aktiviranega polimera za ločevanje proteina in polipeptidnih multimerovInfo
- Publication number
- SI1848458T1 SI1848458T1 SI200630466T SI200630466T SI1848458T1 SI 1848458 T1 SI1848458 T1 SI 1848458T1 SI 200630466 T SI200630466 T SI 200630466T SI 200630466 T SI200630466 T SI 200630466T SI 1848458 T1 SI1848458 T1 SI 1848458T1
- Authority
- SI
- Slovenia
- Prior art keywords
- protein
- separation
- activated polymers
- polypeptide multimers
- polypeptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05003332 | 2005-02-16 | ||
| EP06706962A EP1848458B1 (en) | 2005-02-16 | 2006-02-15 | Use of activated polymers for separation of protein and polypeptide multimers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1848458T1 true SI1848458T1 (sl) | 2010-01-29 |
Family
ID=36168573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200630466T SI1848458T1 (sl) | 2005-02-16 | 2006-02-15 | Uporaba aktiviranega polimera za ločevanje proteina in polipeptidnih multimerov |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080312411A1 (sl) |
| EP (1) | EP1848458B1 (sl) |
| JP (1) | JP2008530163A (sl) |
| AT (1) | ATE447414T1 (sl) |
| AU (2) | AU2006215823A1 (sl) |
| CA (1) | CA2594666A1 (sl) |
| DE (1) | DE602006010176D1 (sl) |
| DK (1) | DK1848458T3 (sl) |
| ES (1) | ES2335304T3 (sl) |
| HR (1) | HRP20090594T1 (sl) |
| SI (1) | SI1848458T1 (sl) |
| WO (1) | WO2006087178A1 (sl) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2331139B1 (en) * | 2008-09-11 | 2019-04-17 | Nektar Therapeutics | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method |
| US9315514B2 (en) | 2012-08-27 | 2016-04-19 | Rhodes Technologies | 1,3-dioxanomorphides and 1,3-dioxanocodides |
| TW201434837A (zh) | 2012-12-14 | 2014-09-16 | Purdue Pharma Lp | 螺環嗎啡喃及其用途 |
| US8980906B2 (en) | 2012-12-14 | 2015-03-17 | Purdue Pharma L.P. | Pyridonemorphinan analogs and biological activity on opioid receptors |
| JP6163210B2 (ja) | 2012-12-14 | 2017-07-12 | パーデュー、ファーマ、リミテッド、パートナーシップ | 窒素含有モルフィナン誘導体およびその使用 |
| CA2896202A1 (en) | 2012-12-28 | 2014-07-03 | Purdue Pharma L.P. | Substituted morphinans and the use thereof |
| JP6159416B2 (ja) | 2012-12-28 | 2017-07-05 | パーデュー、ファーマ、リミテッド、パートナーシップ | ７，８−環式モルフィナン類似体 |
| JP6181770B2 (ja) | 2012-12-31 | 2017-08-16 | ローズ テクノロジーズ | ７β−置換６α，１４α−エテノモルフィナンおよび７β−置換６α，１４α−エタノモルフィナンを調製するための方法 |
| US9340542B2 (en) | 2013-12-26 | 2016-05-17 | Purdue Pharma L.P. | Propellane-based compounds and the use thereof |
| EP3087078B1 (en) | 2013-12-26 | 2019-05-15 | Purdue Pharma LP | 7-beta-alkyl analogs of orvinols |
| US9994571B2 (en) | 2013-12-26 | 2018-06-12 | Purdue Pharma L.P. | 10-substituted morphinan hydantoins |
| EP3087079B1 (en) | 2013-12-26 | 2019-04-03 | Purdue Pharma LP | Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans |
| US9902726B2 (en) | 2013-12-30 | 2018-02-27 | Purdue Pharma L.P. | Pyridone-sulfone morphinan analogs as opioid receptor ligands |
| MX2019007327A (es) | 2016-12-23 | 2019-09-02 | Minoryx Therapeutics S L | Proceso para preparar 5-[[4-[2-[5-(1-hidroxietil)-2-piridinil] etoxi]fenil]metil]-2,4-tiazolidindiona y sus sales. |
| EP3755704A1 (en) | 2018-02-23 | 2020-12-30 | Rhodes Technologies Inc. | Novel opioid compounds and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5312808A (en) * | 1989-11-22 | 1994-05-17 | Enzon, Inc. | Fractionation of polyalkylene oxide-conjugated hemoglobin solutions |
| ES2367891T3 (es) * | 2000-09-29 | 2011-11-10 | Schering Corporation | Interleucina-10 pegilada. |
| JP2005512951A (ja) * | 2001-06-22 | 2005-05-12 | ファーマシア コーポレーション | 化学修飾されたプロゲニポイエチンコンジュゲート |
-
2006
- 2006-02-15 DE DE602006010176T patent/DE602006010176D1/de active Active
- 2006-02-15 US US11/884,300 patent/US20080312411A1/en not_active Abandoned
- 2006-02-15 EP EP06706962A patent/EP1848458B1/en active Active
- 2006-02-15 AT AT06706962T patent/ATE447414T1/de active
- 2006-02-15 SI SI200630466T patent/SI1848458T1/sl unknown
- 2006-02-15 JP JP2007555522A patent/JP2008530163A/ja not_active Withdrawn
- 2006-02-15 CA CA002594666A patent/CA2594666A1/en not_active Abandoned
- 2006-02-15 WO PCT/EP2006/001359 patent/WO2006087178A1/en active Application Filing
- 2006-02-15 AU AU2006215823A patent/AU2006215823A1/en not_active Abandoned
- 2006-02-15 DK DK06706962.5T patent/DK1848458T3/da active
- 2006-02-15 ES ES06706962T patent/ES2335304T3/es active Active
-
2007
- 2007-11-27 AU AU2007237199A patent/AU2007237199A1/en not_active Withdrawn
-
2009
- 2009-11-04 HR HR20090594T patent/HRP20090594T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008530163A (ja) | 2008-08-07 |
| US20080312411A1 (en) | 2008-12-18 |
| CA2594666A1 (en) | 2006-08-24 |
| AU2007237199A1 (en) | 2008-01-17 |
| DE602006010176D1 (de) | 2009-12-17 |
| ATE447414T1 (de) | 2009-11-15 |
| HRP20090594T1 (hr) | 2009-12-31 |
| EP1848458B1 (en) | 2009-11-04 |
| DK1848458T3 (da) | 2010-02-01 |
| EP1848458A1 (en) | 2007-10-31 |
| ES2335304T3 (es) | 2010-03-24 |
| AU2006215823A1 (en) | 2006-08-24 |
| WO2006087178A1 (en) | 2006-08-24 |
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