SI1703965T1 - Naprava, postopek in uporaba za izdelavo majhnih delcev - Google Patents

Naprava, postopek in uporaba za izdelavo majhnih delcev

Info

Publication number
SI1703965T1
SI1703965T1 SI200432087T SI200432087T SI1703965T1 SI 1703965 T1 SI1703965 T1 SI 1703965T1 SI 200432087 T SI200432087 T SI 200432087T SI 200432087 T SI200432087 T SI 200432087T SI 1703965 T1 SI1703965 T1 SI 1703965T1
Authority
SI
Slovenia
Prior art keywords
formation
small particles
particles
small
Prior art date
Application number
SI200432087T
Other languages
English (en)
Inventor
Mustafa Demirbuker
Original Assignee
Xspray Microparticles Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xspray Microparticles Ab filed Critical Xspray Microparticles Ab
Publication of SI1703965T1 publication Critical patent/SI1703965T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/44Mixers in which the components are pressed through slits
    • B01F25/441Mixers in which the components are pressed through slits characterised by the configuration of the surfaces forming the slits
    • B01F25/4412Mixers in which the components are pressed through slits characterised by the configuration of the surfaces forming the slits the slits being formed between opposed planar surfaces, e.g. pushed again each other by springs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/44Mixers in which the components are pressed through slits
    • B01F25/442Mixers in which the components are pressed through slits characterised by the relative position of the surfaces during operation
    • B01F25/4422Mixers in which the components are pressed through slits characterised by the relative position of the surfaces during operation the surfaces being maintained in a fixed but adjustable position, spaced from each other, therefore allowing the slit spacing to be varied
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nozzles (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)
SI200432087T 2003-12-22 2004-12-20 Naprava, postopek in uporaba za izdelavo majhnih delcev SI1703965T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0303476A SE0303476D0 (sv) 2003-12-22 2003-12-22 Device, method and use for the formation of small particles
PCT/SE2004/001936 WO2005061090A1 (en) 2003-12-22 2004-12-20 Device, method and use for the formation of small particles
EP04809109.4A EP1703965B1 (en) 2003-12-22 2004-12-20 Device, method and use for the formation of small particles

Publications (1)

Publication Number Publication Date
SI1703965T1 true SI1703965T1 (sl) 2013-11-29

Family

ID=30768795

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200432087T SI1703965T1 (sl) 2003-12-22 2004-12-20 Naprava, postopek in uporaba za izdelavo majhnih delcev

Country Status (12)

Country Link
US (2) US7798475B2 (sl)
EP (1) EP1703965B1 (sl)
JP (1) JP5032848B2 (sl)
CN (1) CN100528316C (sl)
AU (1) AU2004305413B2 (sl)
CA (1) CA2550806C (sl)
DK (1) DK1703965T3 (sl)
ES (1) ES2429064T3 (sl)
PL (1) PL1703965T3 (sl)
SE (1) SE0303476D0 (sl)
SI (1) SI1703965T1 (sl)
WO (1) WO2005061090A1 (sl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0303476D0 (sv) * 2003-12-22 2003-12-22 Censdelivery Ab Device, method and use for the formation of small particles
CN101918123B (zh) * 2007-12-07 2013-12-18 X喷雾微粒公司 生产微粒的方法与装置
EP2579973A4 (en) * 2010-06-14 2017-01-18 Xspray Microparticles Ab Apparatus and method for the production of particles
AU2011305566A1 (en) * 2010-09-22 2013-05-02 Map Pharmaceuticals, Inc. Aerosol composition for administering drugs
CA2860973C (en) 2012-01-13 2021-10-26 Xspray Microparticles Ab A method for producing stable, amorphous hybrid nanoparticles comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component.
EP2705838A1 (en) 2012-09-06 2014-03-12 Xspray Microparticles Ab Tiotropium preparations
JP2017500182A (ja) * 2013-10-10 2017-01-05 ニューヨーク ユニヴァーシティNew York University ナノ粒子の効率的捕集
US10206873B1 (en) 2017-08-04 2019-02-19 Colorado Can Llc Dry powder formation using a variably constrained, divided pathway for mixing fluid streams
CN116808044A (zh) 2018-06-15 2023-09-29 汉达癌症医药责任有限公司 激酶抑制剂的盐类及其组合物
CN110605036B (zh) * 2019-08-30 2022-05-10 扬州大学 一种可非等动量受限射流撞击混合的方法
EP4168170A1 (en) * 2020-06-18 2023-04-26 Capsugel Belgium NV Method for making multiparticulates from a liquid feed employing a spinning disc sprayer
EP4190437A1 (en) 2021-12-03 2023-06-07 SiTec PharmaBio SL Process and apparatus for the manufacture of solid microparticles
WO2024074585A2 (en) 2022-10-05 2024-04-11 Mireca Medicines Gmbh MICROPARTICLE AND IMPLANT FORMULATIONS FOR cGMP ANALOG THERAPY

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5117145B2 (sl) * 1971-09-10 1976-05-31
FI51602C (fi) * 1973-12-19 1977-02-10 Outokumpu Oy Tapa ja laite sulan aineen hajottamiseksi kaasumaisen tai höyrymäisen aineen suihkulla.
US4206160A (en) * 1978-09-25 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Mechanical device to produce a finely dispersed aerosol
US4284590A (en) * 1980-09-17 1981-08-18 Respiratory Care, Inc. Multiple aspirator for nebulizer
US5232164A (en) * 1990-05-09 1993-08-03 Resch D R Precisely adjustable atomizer
GB9313642D0 (en) 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
CA2112093C (en) * 1993-12-21 1995-02-21 John A. Burgener Parallel path induction nebulizer
US5609798A (en) * 1995-06-07 1997-03-11 Msp Corporation High output PSL aerosol generator
SE504449C2 (sv) * 1995-06-22 1997-02-17 Libradon Ab Anordning för blandning av luft och vatten i en vattenrenare
US6086052A (en) * 1996-12-03 2000-07-11 Rowe; Carroll G. Foam generating apparatus
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
US6076748A (en) * 1998-05-04 2000-06-20 Resch; Darrel R. Odor control atomizer utilizing ozone and water
GB9915975D0 (en) 1999-07-07 1999-09-08 Bradford Particle Design Ltd Method for the formation of particles
TW586963B (en) * 2001-07-20 2004-05-11 Nektar Therapeutics Uk Ltd Method and apparatus for preparing target substance in particulate form and fluid inlet assembly for said apparatus
SE0303476D0 (sv) * 2003-12-22 2003-12-22 Censdelivery Ab Device, method and use for the formation of small particles
US7694944B2 (en) * 2003-12-22 2010-04-13 Niro A/S Nozzle for atomising a liquid by means of a gas and method of atomising

Also Published As

Publication number Publication date
CA2550806C (en) 2012-08-28
EP1703965B1 (en) 2013-07-03
WO2005061090A1 (en) 2005-07-07
AU2004305413A1 (en) 2005-07-07
SE0303476D0 (sv) 2003-12-22
CA2550806A1 (en) 2005-07-07
US20070116650A1 (en) 2007-05-24
AU2004305413B2 (en) 2010-11-18
EP1703965A1 (en) 2006-09-27
PL1703965T3 (pl) 2013-12-31
US8167279B2 (en) 2012-05-01
CN100528316C (zh) 2009-08-19
US7798475B2 (en) 2010-09-21
JP2007515290A (ja) 2007-06-14
DK1703965T3 (da) 2013-09-30
JP5032848B2 (ja) 2012-09-26
CN1917939A (zh) 2007-02-21
US20110049737A1 (en) 2011-03-03
ES2429064T3 (es) 2013-11-12

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