SI1535069T1 - Postopek pregledovanja anti-ligandnih knjižnic za identifikacijo anti-ligandov, specifičnih za diferenčno in redko izražene ligande - Google Patents

Postopek pregledovanja anti-ligandnih knjižnic za identifikacijo anti-ligandov, specifičnih za diferenčno in redko izražene ligande

Info

Publication number
SI1535069T1
SI1535069T1 SI200331394T SI200331394T SI1535069T1 SI 1535069 T1 SI1535069 T1 SI 1535069T1 SI 200331394 T SI200331394 T SI 200331394T SI 200331394 T SI200331394 T SI 200331394T SI 1535069 T1 SI1535069 T1 SI 1535069T1
Authority
SI
Slovenia
Prior art keywords
ligands
ligand
providing
target
differentially
Prior art date
Application number
SI200331394T
Other languages
English (en)
Inventor
Bjorn Frendeus
Original Assignee
Bioinvent Int Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioinvent Int Ab filed Critical Bioinvent Int Ab
Publication of SI1535069T1 publication Critical patent/SI1535069T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SI200331394T 2002-09-04 2003-09-03 Postopek pregledovanja anti-ligandnih knjižnic za identifikacijo anti-ligandov, specifičnih za diferenčno in redko izražene ligande SI1535069T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0220506A GB2392723B (en) 2002-09-04 2002-09-04 Screening methods
EP03793817A EP1535069B1 (en) 2002-09-04 2003-09-03 Method for screening anti-ligand libraries for identifying anti-ligands specific for differentially and infrequently expressed ligands
PCT/EP2003/009991 WO2004023140A1 (en) 2002-09-04 2003-09-03 Method for screening anti-ligand libraries for identifying anti-ligands specific for differentially and infrequently expressed ligands

Publications (1)

Publication Number Publication Date
SI1535069T1 true SI1535069T1 (sl) 2008-12-31

Family

ID=9943455

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200331394T SI1535069T1 (sl) 2002-09-04 2003-09-03 Postopek pregledovanja anti-ligandnih knjižnic za identifikacijo anti-ligandov, specifičnih za diferenčno in redko izražene ligande

Country Status (11)

Country Link
US (3) US8592347B2 (sl)
EP (1) EP1535069B1 (sl)
AT (1) ATE403865T1 (sl)
AU (1) AU2003266366A1 (sl)
DE (1) DE60322717D1 (sl)
DK (1) DK1535069T3 (sl)
ES (1) ES2314280T3 (sl)
GB (1) GB2392723B (sl)
PT (1) PT1535069E (sl)
SI (1) SI1535069T1 (sl)
WO (1) WO2004023140A1 (sl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2392723B (en) * 2002-09-04 2005-01-12 Bioinvent Int Ab Screening methods
GB0525214D0 (en) 2005-12-12 2006-01-18 Bioinvent Int Ab Biological materials and uses thereof
GB201116364D0 (en) * 2011-09-22 2011-11-02 Bioinvent Int Ab Screening methods and uses thereof
KR101580360B1 (ko) * 2013-05-22 2015-12-28 김성천 연자성미세구조물을 이용한 리간드의 스크리닝 시스템 및 그 용도
US10018635B2 (en) * 2014-07-30 2018-07-10 Novilytic, LLC Method for analyzing samples of a biological fluid
WO2023242125A1 (en) 2022-06-13 2023-12-21 Bioinvent International Ab Methods of isolating anti-ligands

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366862A (en) * 1990-02-14 1994-11-22 Receptor Laboratories, Inc. Method for generating and screening useful peptides
AU8081491A (en) 1990-06-01 1991-12-31 Cetus Corporation Compositions and methods for identifying biologically active molecules
AU1378495A (en) * 1993-12-27 1995-07-17 Hamilton Civic Hospitals Research Development, Inc. Methods and compositions for inhibiting thrombogenesis
US6794128B2 (en) * 1998-04-24 2004-09-21 The Regents Of The University Of California Methods of selecting internalizing antibodies
WO2000052054A2 (en) * 1999-03-01 2000-09-08 Genentech, Inc. Antibodies for cancer therapy and diagnosis
US7135287B1 (en) * 1999-10-02 2006-11-14 Biosite, Inc. Human antibodies
US20050130320A1 (en) * 2000-11-09 2005-06-16 George Shaji. T. Method for identifying the proteome of cells using an antibody library microarray
GB2392723B (en) 2002-09-04 2005-01-12 Bioinvent Int Ab Screening methods
US20090005257A1 (en) 2003-05-14 2009-01-01 Jespers Laurent S Process for Recovering Polypeptides that Unfold Reversibly from a Polypeptide Repertoire
CN101333243A (zh) 2003-05-14 2008-12-31 多曼蒂斯有限公司 从多肽全能文库恢复可逆可解折叠多肽的方法
US20110052565A1 (en) 2007-12-21 2011-03-03 National Research Council Of Canada Non-aggregating human vh domains
GB201116364D0 (en) 2011-09-22 2011-11-02 Bioinvent Int Ab Screening methods and uses thereof

Also Published As

Publication number Publication date
US8592347B2 (en) 2013-11-26
DK1535069T3 (da) 2008-11-10
ES2314280T3 (es) 2009-03-16
US20140200152A1 (en) 2014-07-17
AU2003266366A1 (en) 2004-03-29
ATE403865T1 (de) 2008-08-15
GB2392723A (en) 2004-03-10
EP1535069A1 (en) 2005-06-01
WO2004023140A1 (en) 2004-03-18
GB2392723B (en) 2005-01-12
PT1535069E (pt) 2008-10-08
US20060199219A1 (en) 2006-09-07
US20160312383A1 (en) 2016-10-27
US10351970B2 (en) 2019-07-16
DE60322717D1 (de) 2008-09-18
GB0220506D0 (en) 2002-10-09
EP1535069B1 (en) 2008-08-06

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