PT1535069E - Método para rastreio de bibliotecas de anti-ligandos para identificar anti-ligandos específicos para ligandos expressos diferencialmente e com pouca frequência - Google Patents
Método para rastreio de bibliotecas de anti-ligandos para identificar anti-ligandos específicos para ligandos expressos diferencialmente e com pouca frequência Download PDFInfo
- Publication number
- PT1535069E PT1535069E PT03793817T PT03793817T PT1535069E PT 1535069 E PT1535069 E PT 1535069E PT 03793817 T PT03793817 T PT 03793817T PT 03793817 T PT03793817 T PT 03793817T PT 1535069 E PT1535069 E PT 1535069E
- Authority
- PT
- Portugal
- Prior art keywords
- ligands
- ligand
- providing
- target
- differentially
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0220506A GB2392723B (en) | 2002-09-04 | 2002-09-04 | Screening methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1535069E true PT1535069E (pt) | 2008-10-08 |
Family
ID=9943455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT03793817T PT1535069E (pt) | 2002-09-04 | 2003-09-03 | Método para rastreio de bibliotecas de anti-ligandos para identificar anti-ligandos específicos para ligandos expressos diferencialmente e com pouca frequência |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8592347B2 (pt) |
| EP (1) | EP1535069B1 (pt) |
| AT (1) | ATE403865T1 (pt) |
| AU (1) | AU2003266366A1 (pt) |
| DE (1) | DE60322717D1 (pt) |
| DK (1) | DK1535069T3 (pt) |
| ES (1) | ES2314280T3 (pt) |
| GB (1) | GB2392723B (pt) |
| PT (1) | PT1535069E (pt) |
| SI (1) | SI1535069T1 (pt) |
| WO (1) | WO2004023140A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2392723B (en) * | 2002-09-04 | 2005-01-12 | Bioinvent Int Ab | Screening methods |
| GB0525214D0 (en) | 2005-12-12 | 2006-01-18 | Bioinvent Int Ab | Biological materials and uses thereof |
| GB201116364D0 (en) * | 2011-09-22 | 2011-11-02 | Bioinvent Int Ab | Screening methods and uses thereof |
| KR101580360B1 (ko) * | 2013-05-22 | 2015-12-28 | 김성천 | 연자성미세구조물을 이용한 리간드의 스크리닝 시스템 및 그 용도 |
| US10018635B2 (en) * | 2014-07-30 | 2018-07-10 | Novilytic, LLC | Method for analyzing samples of a biological fluid |
| WO2023242125A1 (en) | 2022-06-13 | 2023-12-21 | Bioinvent International Ab | Methods of isolating anti-ligands |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5366862A (en) * | 1990-02-14 | 1994-11-22 | Receptor Laboratories, Inc. | Method for generating and screening useful peptides |
| AU8081491A (en) | 1990-06-01 | 1991-12-31 | Cetus Corporation | Compositions and methods for identifying biologically active molecules |
| AU1378495A (en) * | 1993-12-27 | 1995-07-17 | Hamilton Civic Hospitals Research Development, Inc. | Methods and compositions for inhibiting thrombogenesis |
| US6794128B2 (en) * | 1998-04-24 | 2004-09-21 | The Regents Of The University Of California | Methods of selecting internalizing antibodies |
| WO2000052054A2 (en) * | 1999-03-01 | 2000-09-08 | Genentech, Inc. | Antibodies for cancer therapy and diagnosis |
| US7135287B1 (en) * | 1999-10-02 | 2006-11-14 | Biosite, Inc. | Human antibodies |
| US20050130320A1 (en) * | 2000-11-09 | 2005-06-16 | George Shaji. T. | Method for identifying the proteome of cells using an antibody library microarray |
| GB2392723B (en) | 2002-09-04 | 2005-01-12 | Bioinvent Int Ab | Screening methods |
| US20090005257A1 (en) | 2003-05-14 | 2009-01-01 | Jespers Laurent S | Process for Recovering Polypeptides that Unfold Reversibly from a Polypeptide Repertoire |
| CN101333243A (zh) | 2003-05-14 | 2008-12-31 | 多曼蒂斯有限公司 | 从多肽全能文库恢复可逆可解折叠多肽的方法 |
| US20110052565A1 (en) | 2007-12-21 | 2011-03-03 | National Research Council Of Canada | Non-aggregating human vh domains |
| GB201116364D0 (en) | 2011-09-22 | 2011-11-02 | Bioinvent Int Ab | Screening methods and uses thereof |
-
2002
- 2002-09-04 GB GB0220506A patent/GB2392723B/en not_active Expired - Fee Related
-
2003
- 2003-09-03 AU AU2003266366A patent/AU2003266366A1/en not_active Abandoned
- 2003-09-03 SI SI200331394T patent/SI1535069T1/sl unknown
- 2003-09-03 DE DE60322717T patent/DE60322717D1/de not_active Expired - Lifetime
- 2003-09-03 US US10/526,695 patent/US8592347B2/en active Active
- 2003-09-03 EP EP03793817A patent/EP1535069B1/en not_active Expired - Lifetime
- 2003-09-03 DK DK03793817T patent/DK1535069T3/da active
- 2003-09-03 PT PT03793817T patent/PT1535069E/pt unknown
- 2003-09-03 ES ES03793817T patent/ES2314280T3/es not_active Expired - Lifetime
- 2003-09-03 AT AT03793817T patent/ATE403865T1/de active
- 2003-09-03 WO PCT/EP2003/009991 patent/WO2004023140A1/en active IP Right Grant
-
2013
- 2013-10-15 US US14/054,392 patent/US20140200152A1/en not_active Abandoned
-
2016
- 2016-02-29 US US15/055,814 patent/US10351970B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US8592347B2 (en) | 2013-11-26 |
| DK1535069T3 (da) | 2008-11-10 |
| ES2314280T3 (es) | 2009-03-16 |
| US20140200152A1 (en) | 2014-07-17 |
| AU2003266366A1 (en) | 2004-03-29 |
| ATE403865T1 (de) | 2008-08-15 |
| GB2392723A (en) | 2004-03-10 |
| EP1535069A1 (en) | 2005-06-01 |
| WO2004023140A1 (en) | 2004-03-18 |
| GB2392723B (en) | 2005-01-12 |
| US20060199219A1 (en) | 2006-09-07 |
| US20160312383A1 (en) | 2016-10-27 |
| SI1535069T1 (sl) | 2008-12-31 |
| US10351970B2 (en) | 2019-07-16 |
| DE60322717D1 (de) | 2008-09-18 |
| GB0220506D0 (en) | 2002-10-09 |
| EP1535069B1 (en) | 2008-08-06 |
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