SI1137438T1 - Formulation with an improved therapeutic range, containing nucleotide synthesis inhibitors - Google Patents

Formulation with an improved therapeutic range, containing nucleotide synthesis inhibitors

Info

Publication number
SI1137438T1
SI1137438T1 SI9930063T SI9930063T SI1137438T1 SI 1137438 T1 SI1137438 T1 SI 1137438T1 SI 9930063 T SI9930063 T SI 9930063T SI 9930063 T SI9930063 T SI 9930063T SI 1137438 T1 SI1137438 T1 SI 1137438T1
Authority
SI
Slovenia
Prior art keywords
formulation
synthesis inhibitors
improved therapeutic
therapeutic range
containing nucleotide
Prior art date
Application number
SI9930063T
Other languages
English (en)
Slovenian (sl)
Inventor
J�rgen LINDNER
Burkhard Haase
Original Assignee
Aventis Pharma Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland Gmbh filed Critical Aventis Pharma Deutschland Gmbh
Publication of SI1137438T1 publication Critical patent/SI1137438T1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
SI9930063T 1998-12-10 1999-12-01 Formulation with an improved therapeutic range, containing nucleotide synthesis inhibitors SI1137438T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19857009A DE19857009A1 (de) 1998-12-10 1998-12-10 Zubereitung mit verbesserter therapeutischer Breite, enthaltend Nukleotidsyntheseinhibitoren
PCT/EP1999/009380 WO2000033876A1 (fr) 1998-12-10 1999-12-01 Formulation a spectre therapeutique elargi, contenant des inhibiteurs de la synthese des nucleotides

Publications (1)

Publication Number Publication Date
SI1137438T1 true SI1137438T1 (en) 2002-08-31

Family

ID=7890633

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930063T SI1137438T1 (en) 1998-12-10 1999-12-01 Formulation with an improved therapeutic range, containing nucleotide synthesis inhibitors

Country Status (30)

Country Link
EP (1) EP1137438B1 (fr)
JP (1) JP2002531525A (fr)
KR (1) KR20010080729A (fr)
CN (1) CN1189214C (fr)
AR (1) AR021577A1 (fr)
AT (1) ATE218370T1 (fr)
AU (1) AU766810B2 (fr)
BG (1) BG105548A (fr)
BR (1) BR9916006A (fr)
CA (1) CA2354266A1 (fr)
CZ (1) CZ20012029A3 (fr)
DE (2) DE19857009A1 (fr)
DK (1) DK1137438T3 (fr)
EA (1) EA005136B1 (fr)
EE (1) EE200100305A (fr)
ES (1) ES2178496T3 (fr)
HK (1) HK1041598B (fr)
HR (1) HRP20010429A2 (fr)
HU (1) HUP0104624A3 (fr)
IL (1) IL143586A0 (fr)
MX (1) MXPA01005861A (fr)
NO (1) NO20012719D0 (fr)
NZ (1) NZ511882A (fr)
PL (1) PL349336A1 (fr)
PT (1) PT1137438E (fr)
SI (1) SI1137438T1 (fr)
SK (1) SK284842B6 (fr)
WO (1) WO2000033876A1 (fr)
YU (1) YU39901A (fr)
ZA (1) ZA200104815B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10112924A1 (de) * 2001-03-13 2002-10-02 Erich Eigenbrodt 1-Butansäurederivate, pharmazeutische Zusammensetzungen enthaltend solche Derivate und Verwendungen solcher Derivate
JP4382354B2 (ja) * 2001-03-13 2009-12-09 ヴァルブルク・グリコムド・ゲーエムベーハー 1−ブタン酸誘導体およびその使用
GB0123571D0 (en) 2001-04-05 2001-11-21 Aventis Pharm Prod Inc Use of (Z)-2-cyano-3-hydroxy-but-2-enoic acid-(4'-trifluoromethylphenyl)-amide for treating multiple sclerosis
US20040127435A1 (en) * 2002-08-02 2004-07-01 Regents Of The University Of California Uses for inhibitors of inosine monophosphate dehydrogenase
AU2003258454A1 (en) 2002-09-06 2004-04-30 Schebo®Biotech Ag Compounds for modulating the glycolosis enzyme complex and/or transaminase complex
JPWO2005060980A1 (ja) * 2003-12-24 2007-12-13 正彬 少名子 疾患治療用医薬及び糖尿病治療用医薬
DE102005017592A1 (de) * 2005-04-16 2006-10-19 Lindner, Jürgen, Dr. med. Darreichungsformen und Kombinationspräparate von Pyrimidinbiosyntheseinhibitoren zur Erzielung zusätzlicher Wirkungen auf das Immunsystem
JP4657384B2 (ja) 2007-05-03 2011-03-23 ファイザー・リミテッド ナトリウムチャンネルモジュレーターとしての2−ピリジンカルボキサミド誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4127737A1 (de) * 1991-08-22 1993-02-25 Hoechst Ag Arzneimittel zur behandlung von abstossungsreaktionen bei organverpflanzungen
EP0538783B1 (fr) * 1991-10-23 1995-09-27 Hoechst Aktiengesellschaft Dérivés d'amides de l'acide n-phényl-cyano-2-hydroxy-3-crotonique et leur utilisation comme médicaments ayant des propriétés immunomodulants
IT1254519B (it) * 1992-03-16 1995-09-25 Chiesi Farma Spa Associazioni di composti ad attivita' antivirale
DE19539638A1 (de) * 1995-10-25 1997-04-30 Hoechst Ag Die Verwendung von Isoxazol- und Crotonsäureamidderivaten zur Behandlung von Krebserkrankungen
AU4596097A (en) * 1996-09-26 1998-04-17 Williams, James W. Improved therapeutic uses of 4-quinoline-carboxylic acid derivatives

Also Published As

Publication number Publication date
BG105548A (en) 2001-12-29
AR021577A1 (es) 2002-07-24
MXPA01005861A (es) 2002-03-27
AU1779300A (en) 2000-06-26
DE59901681D1 (de) 2002-07-11
HRP20010429A2 (en) 2002-06-30
JP2002531525A (ja) 2002-09-24
HK1041598B (zh) 2005-07-15
WO2000033876A1 (fr) 2000-06-15
NO20012719L (no) 2001-06-01
CA2354266A1 (fr) 2000-06-15
NZ511882A (en) 2003-11-28
CN1189214C (zh) 2005-02-16
BR9916006A (pt) 2001-09-04
YU39901A (sh) 2005-06-10
PT1137438E (pt) 2002-11-29
EP1137438B1 (fr) 2002-06-05
DK1137438T3 (da) 2002-10-14
ATE218370T1 (de) 2002-06-15
CZ20012029A3 (cs) 2002-02-13
NO20012719D0 (no) 2001-06-01
HUP0104624A3 (en) 2002-12-28
KR20010080729A (ko) 2001-08-22
AU766810B2 (en) 2003-10-23
PL349336A1 (en) 2002-07-15
CN1329506A (zh) 2002-01-02
IL143586A0 (en) 2002-04-21
HK1041598A1 (en) 2002-07-12
EP1137438A1 (fr) 2001-10-04
DE19857009A1 (de) 2000-06-15
ZA200104815B (en) 2002-06-13
EE200100305A (et) 2002-08-15
EA005136B1 (ru) 2004-12-30
EA200100647A1 (ru) 2001-12-24
HUP0104624A2 (hu) 2002-04-29
SK7882001A3 (en) 2001-12-03
ES2178496T3 (es) 2002-12-16
SK284842B6 (sk) 2005-12-01

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