SI1032386T1 - Use of oxazolidinone derivatives for treating arthritis - Google Patents
Use of oxazolidinone derivatives for treating arthritisInfo
- Publication number
- SI1032386T1 SI1032386T1 SI9830387T SI9830387T SI1032386T1 SI 1032386 T1 SI1032386 T1 SI 1032386T1 SI 9830387 T SI9830387 T SI 9830387T SI 9830387 T SI9830387 T SI 9830387T SI 1032386 T1 SI1032386 T1 SI 1032386T1
- Authority
- SI
- Slovenia
- Prior art keywords
- treating arthritis
- oxazolidinone derivatives
- oxazolidinone
- psoriasis
- arthritis
- Prior art date
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
- 206010003246 arthritis Diseases 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 229940030999 antipsoriatics Drugs 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- TYZROVQLWOKYKF-ZDUSSCGKSA-N linezolid Chemical compound O=C1O[C@@H](CNC(=O)C)CN1C(C=C1F)=CC=C1N1CCOCC1 TYZROVQLWOKYKF-ZDUSSCGKSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6568997P | 1997-11-18 | 1997-11-18 | |
| US7129798P | 1998-01-16 | 1998-01-16 | |
| US7366298P | 1998-02-04 | 1998-02-04 | |
| US7524798P | 1998-02-19 | 1998-02-19 | |
| US7767298P | 1998-03-12 | 1998-03-12 | |
| EP98960157A EP1032386B1 (en) | 1997-11-18 | 1998-11-10 | Use of oxazolidinone derivatives for treating arthritis |
| PCT/US1998/023233 WO1999025344A1 (en) | 1997-11-18 | 1998-11-10 | Use of oxazolidinone derivatives for treating psoriasis, arthritis and reducing the toxicity of cancer chemotherapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1032386T1 true SI1032386T1 (en) | 2003-06-30 |
Family
ID=27535698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9830387T SI1032386T1 (en) | 1997-11-18 | 1998-11-10 | Use of oxazolidinone derivatives for treating arthritis |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1032386B1 (https=) |
| JP (1) | JP2001522886A (https=) |
| KR (2) | KR100574307B1 (https=) |
| CN (2) | CN1546030A (https=) |
| AT (1) | ATE233092T1 (https=) |
| AU (1) | AU743941B2 (https=) |
| BR (1) | BR9815615A (https=) |
| CA (1) | CA2303961A1 (https=) |
| DE (1) | DE69811717T2 (https=) |
| DK (1) | DK1032386T3 (https=) |
| ES (1) | ES2193592T3 (https=) |
| NZ (1) | NZ504612A (https=) |
| PT (1) | PT1032386E (https=) |
| SI (1) | SI1032386T1 (https=) |
| WO (1) | WO1999025344A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999064417A2 (en) | 1998-06-05 | 1999-12-16 | Astrazeneca Ab | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them |
| KR20020063851A (ko) * | 1999-09-13 | 2002-08-05 | 인사이트 비젼 인코포레이티드 | 안구 감염 예방용 국소 치료제 |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| US6451345B1 (en) | 2000-01-20 | 2002-09-17 | Eurand Pharmaceuticals Ltd. | Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| IL139975A0 (en) * | 2000-11-29 | 2002-02-10 | Univ Ramot | Anti proliferative drugs |
| US20050250709A1 (en) * | 2003-12-19 | 2005-11-10 | Bionaut Pharmaceuticals | Anti-neoplastic agents, combination therapies and related methods |
| CN107456442A (zh) * | 2016-06-03 | 2017-12-12 | 四川赛卓药业股份有限公司 | 一种噁唑烷酮化合物的亚微乳注射剂及其制备方法和用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0610265B1 (en) * | 1991-11-01 | 1996-12-27 | PHARMACIA & UPJOHN COMPANY | Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents |
| SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| CA2174107C (en) * | 1993-11-22 | 2005-04-12 | Steven J. Brickner | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
-
1998
- 1998-11-10 SI SI9830387T patent/SI1032386T1/xx unknown
- 1998-11-10 CN CNA2004100027903A patent/CN1546030A/zh active Pending
- 1998-11-10 KR KR1020007005366A patent/KR100574307B1/ko not_active Expired - Fee Related
- 1998-11-10 AU AU15823/99A patent/AU743941B2/en not_active Ceased
- 1998-11-10 DK DK98960157T patent/DK1032386T3/da active
- 1998-11-10 JP JP2000520777A patent/JP2001522886A/ja not_active Withdrawn
- 1998-11-10 KR KR1020057017426A patent/KR100589545B1/ko not_active Expired - Fee Related
- 1998-11-10 BR BR9815615-2A patent/BR9815615A/pt not_active Application Discontinuation
- 1998-11-10 CN CNB988100134A patent/CN1142777C/zh not_active Expired - Fee Related
- 1998-11-10 WO PCT/US1998/023233 patent/WO1999025344A1/en not_active Ceased
- 1998-11-10 PT PT98960157T patent/PT1032386E/pt unknown
- 1998-11-10 NZ NZ504612A patent/NZ504612A/xx unknown
- 1998-11-10 CA CA002303961A patent/CA2303961A1/en not_active Abandoned
- 1998-11-10 ES ES98960157T patent/ES2193592T3/es not_active Expired - Lifetime
- 1998-11-10 AT AT98960157T patent/ATE233092T1/de not_active IP Right Cessation
- 1998-11-10 DE DE69811717T patent/DE69811717T2/de not_active Expired - Fee Related
- 1998-11-10 EP EP98960157A patent/EP1032386B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU743941B2 (en) | 2002-02-07 |
| WO1999025344A1 (en) | 1999-05-27 |
| ATE233092T1 (de) | 2003-03-15 |
| CN1546030A (zh) | 2004-11-17 |
| AU1582399A (en) | 1999-06-07 |
| KR100574307B1 (ko) | 2006-04-27 |
| BR9815615A (pt) | 2000-10-24 |
| EP1032386B1 (en) | 2003-02-26 |
| DE69811717D1 (de) | 2003-04-03 |
| NZ504612A (en) | 2002-08-28 |
| PT1032386E (pt) | 2003-07-31 |
| CA2303961A1 (en) | 1999-05-27 |
| KR100589545B1 (ko) | 2006-06-19 |
| EP1032386A1 (en) | 2000-09-06 |
| DE69811717T2 (de) | 2003-10-16 |
| ES2193592T3 (es) | 2003-11-01 |
| CN1299281A (zh) | 2001-06-13 |
| HK1036591A1 (en) | 2002-01-11 |
| DK1032386T3 (da) | 2003-05-26 |
| JP2001522886A (ja) | 2001-11-20 |
| KR20050100009A (ko) | 2005-10-17 |
| KR20010032178A (ko) | 2001-04-16 |
| CN1142777C (zh) | 2004-03-24 |
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