SG193447A1 - Cd37-binding molecules and immunoconjugates thereof - Google Patents
Cd37-binding molecules and immunoconjugates thereof Download PDFInfo
- Publication number
- SG193447A1 SG193447A1 SG2013069026A SG2013069026A SG193447A1 SG 193447 A1 SG193447 A1 SG 193447A1 SG 2013069026 A SG2013069026 A SG 2013069026A SG 2013069026 A SG2013069026 A SG 2013069026A SG 193447 A1 SG193447 A1 SG 193447A1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
- C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
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- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K2317/624—Disulfide-stabilized antibody (dsFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/626—Diabody or triabody
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Physical Education & Sports Medicine (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
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- Neurology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
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- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161470863P | 2011-04-01 | 2011-04-01 | |
| PCT/US2012/031648 WO2012135740A2 (en) | 2011-04-01 | 2012-03-30 | Cd37-binding molecules and immunoconjugates thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG193447A1 true SG193447A1 (en) | 2013-10-30 |
Family
ID=46932414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013069026A SG193447A1 (en) | 2011-04-01 | 2012-03-30 | Cd37-binding molecules and immunoconjugates thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US9447189B2 (enExample) |
| EP (1) | EP2694105A4 (enExample) |
| JP (2) | JP6018622B2 (enExample) |
| KR (1) | KR20140031883A (enExample) |
| CN (2) | CN105999293B (enExample) |
| AU (2) | AU2012236210B2 (enExample) |
| BR (1) | BR112013025208A2 (enExample) |
| CA (1) | CA2831111A1 (enExample) |
| EA (1) | EA201391342A1 (enExample) |
| IL (1) | IL228537A0 (enExample) |
| MX (1) | MX2013011385A (enExample) |
| SG (1) | SG193447A1 (enExample) |
| WO (1) | WO2012135740A2 (enExample) |
| ZA (1) | ZA201307302B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX338932B (es) | 2010-03-12 | 2016-05-06 | Immunogen Inc | Moleculas de union cd37 y sus inmunoconjugados. |
| CN105999293B (zh) | 2011-04-01 | 2019-07-23 | 德彪发姆国际有限公司 | Cd37结合分子及其免疫缀合物 |
| WO2014089177A2 (en) | 2012-12-04 | 2014-06-12 | Massachusetts Institute Of Technology | Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines |
| AU2015311951B2 (en) | 2014-09-02 | 2021-04-08 | Immunogen, Inc. | Methods for formulating antibody drug conjugate compositions |
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| CN105999293A (zh) | 2016-10-12 |
| EP2694105A2 (en) | 2014-02-12 |
| JP6018622B2 (ja) | 2016-11-02 |
| CN105999293B (zh) | 2019-07-23 |
| KR20140031883A (ko) | 2014-03-13 |
| AU2012236210A1 (en) | 2013-03-28 |
| WO2012135740A3 (en) | 2013-11-07 |
| JP2016145254A (ja) | 2016-08-12 |
| IL228537A0 (en) | 2013-12-31 |
| AU2016200175A1 (en) | 2016-02-04 |
| MX2013011385A (es) | 2014-03-13 |
| US10556958B2 (en) | 2020-02-11 |
| US9447189B2 (en) | 2016-09-20 |
| BR112013025208A2 (pt) | 2018-09-11 |
| NZ710201A (en) | 2016-06-24 |
| WO2012135740A2 (en) | 2012-10-04 |
| CN103596590A (zh) | 2014-02-19 |
| US20120276119A1 (en) | 2012-11-01 |
| EP2694105A4 (en) | 2015-04-29 |
| AU2012236210B2 (en) | 2016-02-04 |
| CA2831111A1 (en) | 2012-10-04 |
| US20160340438A1 (en) | 2016-11-24 |
| JP2014515742A (ja) | 2014-07-03 |
| ZA201307302B (en) | 2022-03-30 |
| NZ615735A (en) | 2015-08-28 |
| US20200270361A1 (en) | 2020-08-27 |
| EA201391342A1 (ru) | 2014-11-28 |
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