SG177956A1 - Gene expression signatures in blood leukocytes permit differential diagnosis of acute infections - Google Patents

Gene expression signatures in blood leukocytes permit differential diagnosis of acute infections Download PDF

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Publication number
SG177956A1
SG177956A1 SG2012000949A SG2012000949A SG177956A1 SG 177956 A1 SG177956 A1 SG 177956A1 SG 2012000949 A SG2012000949 A SG 2012000949A SG 2012000949 A SG2012000949 A SG 2012000949A SG 177956 A1 SG177956 A1 SG 177956A1
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Singapore
Prior art keywords
genes
expression
determining
patients
sample
Prior art date
Application number
SG2012000949A
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English (en)
Inventor
Jacques F Banchereau
Anna Karolina Palucka
Octavio Ramilo
Damien Chaussabel
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Baylor Res Inst
Univ Texas
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Publication date
Application filed by Baylor Res Inst, Univ Texas filed Critical Baylor Res Inst
Publication of SG177956A1 publication Critical patent/SG177956A1/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG2012000949A 2006-08-11 2007-08-10 Gene expression signatures in blood leukocytes permit differential diagnosis of acute infections SG177956A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83714806P 2006-08-11 2006-08-11

Publications (1)

Publication Number Publication Date
SG177956A1 true SG177956A1 (en) 2012-02-28

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Family Applications (1)

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SG2012000949A SG177956A1 (en) 2006-08-11 2007-08-10 Gene expression signatures in blood leukocytes permit differential diagnosis of acute infections

Country Status (8)

Country Link
US (1) US20080171323A1 (cg-RX-API-DMAC7.html)
EP (1) EP2057286A4 (cg-RX-API-DMAC7.html)
JP (2) JP2010500038A (cg-RX-API-DMAC7.html)
CN (1) CN101541976A (cg-RX-API-DMAC7.html)
AU (1) AU2007286915B2 (cg-RX-API-DMAC7.html)
CA (1) CA2695935A1 (cg-RX-API-DMAC7.html)
SG (1) SG177956A1 (cg-RX-API-DMAC7.html)
WO (1) WO2008024642A2 (cg-RX-API-DMAC7.html)

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US20110078194A1 (en) * 2009-09-28 2011-03-31 Oracle International Corporation Sequential information retrieval
US10552710B2 (en) * 2009-09-28 2020-02-04 Oracle International Corporation Hierarchical sequential clustering
US9709565B2 (en) 2010-04-21 2017-07-18 Memed Diagnostics Ltd. Signatures and determinants for distinguishing between a bacterial and viral infection and methods of use thereof
EP2812700B1 (en) 2012-02-09 2018-04-18 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
KR101459186B1 (ko) 2012-04-26 2014-11-07 울산대학교 산학협력단 지속적 황색포도알균 균혈증의 조기 진단용 조성물 및 조기 진단방법
KR20150040289A (ko) * 2012-07-10 2015-04-14 네피안 블루 마운틴스 로컬 헬스 디스트릭트 인플루엔자에서의 위험도 계층화
WO2015048098A1 (en) 2013-09-24 2015-04-02 Washington University Diagnostic methods for infectious disease using endogenous gene expression
WO2015103664A1 (en) * 2014-01-09 2015-07-16 Nepean Blue Montains Local Health District Risk stratification in influenza
JP6661607B2 (ja) 2014-08-14 2020-03-11 メメド ダイアグノスティクス リミテッド 多様体および超平面を用いる生物学的データのコンピュータ分析
EP3182990A4 (en) 2014-08-22 2018-04-11 The Institute of Biophysics Chinese Academy of Sciences Methods and compositions for treating and/or preventing a disease or disorder associated with abnormal level and/or activity of the ifp35 family of proteins
US20170234873A1 (en) 2014-10-14 2017-08-17 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof
WO2016092554A1 (en) 2014-12-11 2016-06-16 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
CN105316404B (zh) * 2015-02-27 2017-02-22 中南大学湘雅二医院 系统性红斑狼疮生物标志物及其诊断试剂盒
AU2016288208A1 (en) * 2015-07-01 2018-02-22 Duke University Methods to diagnose and treat acute respiratory infections
US20180330056A1 (en) * 2015-07-02 2018-11-15 Indevr Inc. Methods of Processing and Classifying Microarray Data for the Detection and Characterization of Pathogens
KR20170027258A (ko) * 2015-09-01 2017-03-09 제이더블유바이오사이언스 주식회사 트립토파닐 티알엔에이 합성효소를 이용한 패혈증의 진단용 조성물과 진단 마커 검출 방법
CN108699583B (zh) * 2016-03-03 2022-11-01 米密德诊断学有限公司 用于区分细菌和病毒感染的rna决定子
CN114959084A (zh) 2016-03-03 2022-08-30 米密德诊断学有限公司 分析rna用于诊断感染类型
CN109804245B (zh) 2016-07-10 2022-10-25 米密德诊断学有限公司 感染的早期诊断
EP3482200B1 (en) 2016-07-10 2022-05-04 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
EP3519834A4 (en) 2016-09-29 2020-06-17 MeMed Diagnostics Ltd. RISK ASSESSMENT AND DISEASE CLASSIFICATION METHODS
US11385241B2 (en) 2016-09-29 2022-07-12 Memed Diagnostics Ltd. Methods of prognosis and treatment
US10209260B2 (en) 2017-07-05 2019-02-19 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
RS61621B1 (sr) * 2017-11-22 2021-04-29 Dewact Labs GmbH Postupak i sredstvo za međusobno razlikovanje virusnih i bakterijskih infekcija
CN108846258B (zh) * 2018-06-08 2021-05-18 中国人民解放军军事科学院军事医学研究院 一种自动检测分节段rna病毒重配的方法
CN112080559B (zh) * 2019-06-14 2023-09-01 复旦大学附属华山医院 Ppp1cb基因snp位点在制备检测寻常型银屑病易感性产品中的应用
CN110656177A (zh) * 2019-10-15 2020-01-07 合肥艾迪康医学检验实验室有限公司 用于检测af1q基因相对表达量的引物、探针及方法和试剂盒
WO2021097336A1 (en) * 2019-11-13 2021-05-20 The Regents Of The University Of Colorado A Body Corporate Identification of host rna biomarkers of infection
JP2023536385A (ja) * 2020-05-29 2023-08-25 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア コロナウイルスを含む呼吸器ウイルスを検出する構成物および方法
JP2023145811A (ja) * 2020-08-17 2023-10-12 孝章 赤池 学習モデルの生成方法、プログラム、演算装置
EP4334474A4 (en) * 2021-05-04 2025-09-10 Inflammatix Inc SYSTEMS AND METHODS FOR ASSESSING A BACTERIAL OR VIRAL STATUS OF A SAMPLE
EP4320262A4 (en) * 2021-05-11 2025-09-03 Inflammatix Inc METHODS FOR DIAGNOSING RESPIRATORY VIRAL INFECTIONS
CN114236140B (zh) * 2021-12-27 2024-06-11 江苏贝索生物工程有限公司 基于试管法的血型智能判读方法
GB2639818A (en) * 2024-01-05 2025-10-08 Cytomics Ltd Fever triage

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Also Published As

Publication number Publication date
EP2057286A2 (en) 2009-05-13
EP2057286A4 (en) 2010-06-16
AU2007286915A1 (en) 2008-02-28
US20080171323A1 (en) 2008-07-17
JP2013066474A (ja) 2013-04-18
WO2008024642A8 (en) 2011-02-17
CN101541976A (zh) 2009-09-23
JP2010500038A (ja) 2010-01-07
CA2695935A1 (en) 2008-02-28
WO2008024642A2 (en) 2008-02-28
AU2007286915A2 (en) 2009-07-09
AU2007286915B2 (en) 2014-05-15
WO2008024642A3 (en) 2008-12-04

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