SG152290A1 - Method for expressing sialylated glycoproteins in mammalian cells and cells thereof - Google Patents

Method for expressing sialylated glycoproteins in mammalian cells and cells thereof

Info

Publication number
SG152290A1
SG152290A1 SG200902998-4A SG2009029984A SG152290A1 SG 152290 A1 SG152290 A1 SG 152290A1 SG 2009029984 A SG2009029984 A SG 2009029984A SG 152290 A1 SG152290 A1 SG 152290A1
Authority
SG
Singapore
Prior art keywords
cells
sialylated glycoproteins
mammalian cells
expressing
expressing sialylated
Prior art date
Application number
SG200902998-4A
Other languages
English (en)
Inventor
Wong Soo Ching Niki Cecilia
Gek Sim Miranda Yap
I-Chyau Daniel Wang
Original Assignee
Univ Singapore
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Singapore, Massachusetts Inst Technology filed Critical Univ Singapore
Publication of SG152290A1 publication Critical patent/SG152290A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG200902998-4A 2004-05-04 2005-05-04 Method for expressing sialylated glycoproteins in mammalian cells and cells thereof SG152290A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56745804P 2004-05-04 2004-05-04

Publications (1)

Publication Number Publication Date
SG152290A1 true SG152290A1 (en) 2009-05-29

Family

ID=35241443

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200902998-4A SG152290A1 (en) 2004-05-04 2005-05-04 Method for expressing sialylated glycoproteins in mammalian cells and cells thereof

Country Status (7)

Country Link
US (1) US20090298120A1 (fr)
EP (1) EP1758614A4 (fr)
JP (1) JP2007535925A (fr)
AU (1) AU2005237951A1 (fr)
CA (1) CA2565410A1 (fr)
SG (1) SG152290A1 (fr)
WO (1) WO2005105156A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8940876B2 (en) 2010-02-08 2015-01-27 Korea Advanced Institute Of Science And Technology Method for preparing recombinant glycoproteins with high sialic acid content
EP2385131A1 (fr) 2010-05-06 2011-11-09 Charité - Universitätsmedizin Berlin Utilisation d'une souche cellulaire modifiée génétiquement exprimant un récepteur de I'asialoglycoprotéine fonctionnel dans la production des glycoprotéines hautement sialylées
JP6652334B2 (ja) * 2014-05-31 2020-02-19 Ｊｃｒファーマ株式会社 ウリジンとｎ−アセチル−ｄ−マンノサミンとを含有する培地
RU2708068C2 (ru) 2014-12-05 2019-12-04 Алексион Фармасьютикалз, Инк. Лечение судорог с использованием рекомбинантной щелочной фосфатазы
US10603361B2 (en) 2015-01-28 2020-03-31 Alexion Pharmaceuticals, Inc. Methods of treating a subject with an alkaline phosphatase deficiency
EP3355904A4 (fr) 2015-09-28 2019-06-12 Alexion Pharmaceuticals, Inc. Identification de régimes posologiques efficaces pour une thérapie de l'hypophosphatasie de remplacement de l'enzyme phosphatase alcaline non spécifique à des tissus (tnsalp)
US11400140B2 (en) 2015-10-30 2022-08-02 Alexion Pharmaceuticals, Inc. Methods for treating craniosynostosis in a patient
WO2017173413A1 (fr) 2016-04-01 2017-10-05 Alexion Pharmaceuticals, Inc. Traitement d'une faiblesse musculaire à l'aide de phosphatases alcalines
CA3057502A1 (fr) 2017-03-31 2018-10-04 Alexion Pharmaceuticals, Inc. Methodes de traitement de l'hypophosphatasie (hpp) chez l'adulte et l'adolescent
JP2021519590A (ja) * 2018-03-30 2021-08-12 アレクシオン ファーマシューティカルズ， インコーポレイテッド 糖タンパク質の製造

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6949372B2 (en) * 1999-03-02 2005-09-27 The Johns Hopkins University Engineering intracellular sialylation pathways
AU3508300A (en) * 1999-03-02 2000-09-21 Human Genome Sciences, Inc. Engineering intracellular sialylation pathways
WO2001042492A1 (fr) * 1999-12-09 2001-06-14 Human Genome Sciences, Inc Procede de creation par genie genetique de trajets de sialylation intracellulaires

Also Published As

Publication number Publication date
US20090298120A1 (en) 2009-12-03
AU2005237951A1 (en) 2005-11-10
JP2007535925A (ja) 2007-12-13
EP1758614A1 (fr) 2007-03-07
WO2005105156A1 (fr) 2005-11-10
CA2565410A1 (fr) 2005-11-10
EP1758614A4 (fr) 2007-09-12

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