AU3508300A - Engineering intracellular sialylation pathways - Google Patents

Engineering intracellular sialylation pathways

Info

Publication number
AU3508300A
AU3508300A AU35083/00A AU3508300A AU3508300A AU 3508300 A AU3508300 A AU 3508300A AU 35083/00 A AU35083/00 A AU 35083/00A AU 3508300 A AU3508300 A AU 3508300A AU 3508300 A AU3508300 A AU 3508300A
Authority
AU
Australia
Prior art keywords
sialylation
pathways
intracellular
engineering
engineering intracellular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU35083/00A
Inventor
Michael J. Betenbaugh
Timothy A Coleman
Don Jarvis
Shawn Lawrence
Yuan C. Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Johns Hopkins University
University of Wyoming
Original Assignee
Human Genome Sciences Inc
Johns Hopkins University
University of Wyoming
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc, Johns Hopkins University, University of Wyoming filed Critical Human Genome Sciences Inc
Publication of AU3508300A publication Critical patent/AU3508300A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01052—Beta-N-acetylhexosaminidase (3.2.1.52)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU35083/00A 1999-03-02 2000-03-01 Engineering intracellular sialylation pathways Abandoned AU3508300A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12258299P 1999-03-02 1999-03-02
US60122582 1999-03-02
US16962499P 1999-12-08 1999-12-08
US60169624 1999-12-08
PCT/US2000/005313 WO2000052135A2 (en) 1999-03-02 2000-03-01 Engineering intracellular sialylation pathways

Publications (1)

Publication Number Publication Date
AU3508300A true AU3508300A (en) 2000-09-21

Family

ID=26820692

Family Applications (1)

Application Number Title Priority Date Filing Date
AU35083/00A Abandoned AU3508300A (en) 1999-03-02 2000-03-01 Engineering intracellular sialylation pathways

Country Status (5)

Country Link
EP (1) EP1399538A4 (en)
JP (1) JP2003524395A (en)
AU (1) AU3508300A (en)
CA (1) CA2363297C (en)
WO (1) WO2000052135A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6949372B2 (en) 1999-03-02 2005-09-27 The Johns Hopkins University Engineering intracellular sialylation pathways
AU2001236739A1 (en) * 2000-02-08 2001-08-20 Genentech Inc. Improved sialylation of glycoproteins
US7863020B2 (en) 2000-06-28 2011-01-04 Glycofi, Inc. Production of sialylated N-glycans in lower eukaryotes
KR100938026B1 (en) 2002-03-07 2010-01-21 아이드게노쉬쉐 테흐니쉐 호흐슐레 쥬리히 System and method for the production of recombinant glycosylated protein in a prokaryotic host
ATE317897T1 (en) * 2002-03-07 2006-03-15 Eidgenoess Tech Hochschule SYSTEM AND METHOD FOR PRODUCING RECOMBINANT GLYCOSYLATED PROTEIN IN PROKARYONTIC HOST CELLS
JP2006333701A (en) * 2003-01-15 2006-12-14 Kazuhito Fujiyama Method for producing glycoprotein having animal type sugar chain
CA2557725C (en) * 2004-02-13 2015-06-30 Glycotope Gmbh Highly active glycoproteins-process conditions and an efficient method for their production
EP1730293A2 (en) * 2004-03-17 2006-12-13 Glycofi, Inc. Method of engineering a cytidine monophosphate-sialic acid synthetic pathway in fungi and yeast
AU2005237951A1 (en) * 2004-05-04 2005-11-10 Massachusetts Institute Of Technology Method for expressing sialylated glycoproteins in mammalian cells and cells thereof
US7479549B2 (en) 2005-02-23 2009-01-20 Jaques John Scott T Recombinant canine thyroid stimulating hormone and methods of production and use thereof
PL2311972T3 (en) 2005-05-11 2015-08-31 Eth Zuerich Recombinant N-glycosylated proteins from procaryotic cells
DE602006015195D1 (en) * 2005-07-12 2010-08-12 Greenovation Biotech Gmbh IMPROVEMENTS OF PROTEIN PRODUCTION OR IN CONNECTION WITH THIS
CA2662226C (en) 2006-09-10 2020-08-04 Glycotope Gmbh Fully human high yield production system for improved antibodies and proteins
EP1920782A1 (en) 2006-11-10 2008-05-14 Glycotope Gmbh Carboyhdrate specific cellular immunity inducing microorganisms and fractions thereof
PL2257307T3 (en) 2008-02-20 2018-11-30 Glaxosmithkline Biologicals S.A. Bioconjugates made from recombinant n-glycosylated proteins from procaryotic cells
EP2501406B8 (en) 2009-11-19 2018-01-24 GlaxoSmithKline Biologicals S.A. Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells
CN103079591B (en) 2010-05-06 2017-07-28 格林考瓦因有限公司 Capsular gram-positive bacteria bioconjugate vaccine
EP2412815A1 (en) * 2010-07-27 2012-02-01 Universite De Rouen N-glycosylation in transformed Phaeodactylum tricornutum
WO2012050175A1 (en) * 2010-10-15 2012-04-19 日本ケミカルリサーチ株式会社 Method for producing glycoprotein having mannose residue as non-reducing end of sugar chain
RU2014110953A (en) 2011-08-22 2015-09-27 Гликотоп Гмбх MICRO-ORGANISMS BEARING TUMOR ANTIGEN
KR20210013107A (en) 2018-05-18 2021-02-03 다이이찌 산쿄 가부시키가이샤 Anti-MUC1 antibody-drug conjugate

Also Published As

Publication number Publication date
JP2003524395A (en) 2003-08-19
WO2000052135A9 (en) 2001-10-11
CA2363297A1 (en) 2000-09-08
CA2363297C (en) 2011-08-09
WO2000052135A3 (en) 2004-01-08
EP1399538A2 (en) 2004-03-24
WO2000052135A2 (en) 2000-09-08
EP1399538A4 (en) 2004-03-24

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase