SG138474A1 - Micro thermal cycler with selective heat isolation - Google Patents

Micro thermal cycler with selective heat isolation

Info

Publication number
SG138474A1
SG138474A1 SG200603945-7A SG2006039457A SG138474A1 SG 138474 A1 SG138474 A1 SG 138474A1 SG 2006039457 A SG2006039457 A SG 2006039457A SG 138474 A1 SG138474 A1 SG 138474A1
Authority
SG
Singapore
Prior art keywords
thermal cycler
micro thermal
selective heat
heat isolation
reaction chambers
Prior art date
Application number
SG200603945-7A
Inventor
Prabhu Vinayak Ashok
Ong Hui Yng
Yap Teck Boon Steven
Original Assignee
Nanyang Polytechnic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanyang Polytechnic filed Critical Nanyang Polytechnic
Priority to SG200603945-7A priority Critical patent/SG138474A1/en
Priority to PCT/SG2007/000041 priority patent/WO2007142604A1/en
Publication of SG138474A1 publication Critical patent/SG138474A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1883—Means for temperature control using thermal insulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

The present invention provides a micro thermal cycler for selectively controlling temperatures of reaction chambers with reaction materials. The micro thermal cycler comprises a selective insulation mechanism and a bulk heating/cooling mechanism. The present invention further provides a microfluidic device for performing chemical and biological reactions within reaction chambers of a microfluidic chip and controlling the temperatures of the reaction chambers by the micro thermal cycler.
SG200603945-7A 2006-06-09 2006-06-09 Micro thermal cycler with selective heat isolation SG138474A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SG200603945-7A SG138474A1 (en) 2006-06-09 2006-06-09 Micro thermal cycler with selective heat isolation
PCT/SG2007/000041 WO2007142604A1 (en) 2006-06-09 2007-02-08 Micro thermal cycler with selective heat isolation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG200603945-7A SG138474A1 (en) 2006-06-09 2006-06-09 Micro thermal cycler with selective heat isolation

Publications (1)

Publication Number Publication Date
SG138474A1 true SG138474A1 (en) 2008-01-28

Family

ID=38801743

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200603945-7A SG138474A1 (en) 2006-06-09 2006-06-09 Micro thermal cycler with selective heat isolation

Country Status (2)

Country Link
SG (1) SG138474A1 (en)
WO (1) WO2007142604A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108472652A (en) * 2015-09-04 2018-08-31 生命技术公司 Reaction site is thermally isolated in substrate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020022261A1 (en) * 1995-06-29 2002-02-21 Anderson Rolfe C. Miniaturized genetic analysis systems and methods
KR100488281B1 (en) * 2001-09-15 2005-05-10 아람 바이오시스템 주식회사 Method and apparatus for amplification of nucleic acid sequences by using thermal convection
JP4695851B2 (en) * 2003-07-10 2011-06-08 シチズンホールディングス株式会社 Micro chemical chip temperature controller
JP2006064365A (en) * 2004-07-29 2006-03-09 Citizen Watch Co Ltd Temperature regulator
KR100604154B1 (en) * 2004-12-10 2006-07-25 한국전자통신연구원 Enhancement of heat transfer rate using 3d structure in PCR chamber

Also Published As

Publication number Publication date
WO2007142604A1 (en) 2007-12-13

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