SG11202113016UA - Information processing device, screening device, information processing method, screening method, and program - Google Patents

Information processing device, screening device, information processing method, screening method, and program

Info

Publication number
SG11202113016UA
SG11202113016UA SG11202113016UA SG11202113016UA SG11202113016UA SG 11202113016U A SG11202113016U A SG 11202113016UA SG 11202113016U A SG11202113016U A SG 11202113016UA SG 11202113016U A SG11202113016U A SG 11202113016UA SG 11202113016U A SG11202113016U A SG 11202113016UA
Authority
SG
Singapore
Prior art keywords
cells
neurodegenerative disease
images
pluripotent stem
differentiated
Prior art date
Application number
SG11202113016UA
Other languages
English (en)
Inventor
Haruhisa Inoue
Takayuki Kondo
Yuichiro YADA
Original Assignee
Univ Kyoto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kyoto filed Critical Univ Kyoto
Publication of SG11202113016UA publication Critical patent/SG11202113016UA/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4082—Diagnosing or monitoring movement diseases, e.g. Parkinson, Huntington or Tourette
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00—Machine learning
    • G06N20/20—Ensemble learning
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/04—Architecture, e.g. interconnection topology
    • G06N3/0464—Convolutional networks [CNN, ConvNet]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/08—Learning methods
    • G06N3/084—Backpropagation, e.g. using gradient descent
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/08—Learning methods
    • G06N3/09—Supervised learning
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/82—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20084—Artificial neural networks [ANN]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30016—Brain
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Data Mining & Analysis (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Databases & Information Systems (AREA)
  • Biophysics (AREA)
  • Software Systems (AREA)
  • Evolutionary Computation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Computing Systems (AREA)
  • Artificial Intelligence (AREA)
  • Neurosurgery (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Engineering & Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Physiology (AREA)
  • Computational Linguistics (AREA)
  • Developmental Disabilities (AREA)
  • Quality & Reliability (AREA)
  • Multimedia (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
SG11202113016UA 2019-05-31 2020-05-28 Information processing device, screening device, information processing method, screening method, and program SG11202113016UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019103293 2019-05-31
PCT/JP2020/021177 WO2020241772A1 (ja) 2019-05-31 2020-05-28 情報処理装置、スクリーニング装置、情報処理方法、スクリーニング方法、及びプログラム

Publications (1)

Publication Number Publication Date
SG11202113016UA true SG11202113016UA (en) 2021-12-30

Family

ID=73552587

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202113016UA SG11202113016UA (en) 2019-05-31 2020-05-28 Information processing device, screening device, information processing method, screening method, and program

Country Status (5)

Country Link
US (1) US12462378B2 (https=)
EP (1) EP3978595A4 (https=)
JP (1) JPWO2020241772A1 (https=)
SG (1) SG11202113016UA (https=)
WO (1) WO2020241772A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7678577B2 (ja) * 2019-05-31 2025-05-16 国立大学法人京都大学 情報処理装置、情報処理方法、及びプログラム
JPWO2020241772A1 (https=) 2019-05-31 2020-12-03
US20230419480A1 (en) * 2020-05-14 2023-12-28 New York Stem Cell Foundation, Inc. Method and system for predicting cellular aging
WO2022061176A1 (en) * 2020-09-18 2022-03-24 New York Stem Cell Foundation, Inc. Methods and systems for predicting neurodegenerative disease state
US12518129B2 (en) * 2020-11-30 2026-01-06 Oracle International Corporation Method and system for over-prediction in neural networks
WO2022251400A1 (en) * 2021-05-26 2022-12-01 Genentech, Inc. Detecting tertiary lymphoid structures in digital pathology images
JPWO2022270179A1 (https=) * 2021-06-24 2022-12-29
CN117597430A (zh) * 2021-07-29 2024-02-23 株式会社岛津制作所 细胞图像分析方法
GB202116864D0 (en) * 2021-11-23 2022-01-05 Ucl Business Ltd Methods and apparatus for analysing imaging data
CN114419500B (zh) * 2022-01-07 2024-11-01 乐普（北京）医疗器械股份有限公司 基于心脏超声视频筛选舒张期和收缩期图像的方法和装置
US20230377355A1 (en) * 2022-05-20 2023-11-23 New York Stem Cell Foundation, Inc. Synthetic pooling for enriching disease signatures
WO2025255827A1 (zh) * 2024-06-14 2025-12-18 京东方科技集团股份有限公司 疾病预测方法、模型的训练方法及装置、存储介质

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7711174B2 (en) * 2004-05-13 2010-05-04 The Charles Stark Draper Laboratory, Inc. Methods and systems for imaging cells
WO2011047103A2 (en) 2009-10-13 2011-04-21 The Charles Stark Draper Laboratory, Inc. Mathematical image analysis based cell reprogramming with applications for epigenetic and non-epigenetic base induced pluripotent stem cell derivation
WO2011108766A1 (en) 2010-03-03 2011-09-09 Kyoto University METHOD FOR DIAGNOSING A PROTEIN MISFOLDING DISEASE USING NERVE CELLS DERIVED FROM iPS CELLS
US20150301030A1 (en) 2014-04-22 2015-10-22 Q-State Biosciences, Inc. Models for parkinson's disease studies
CA2972598C (en) * 2014-12-31 2024-03-12 Wisconsin Alumni Research Foundation Human pluripotent stem cell-based models for predictive developmental neural toxicity
EP3265810A1 (en) 2015-03-06 2018-01-10 Blanchette Rockefeller Neurosciences, Institute Methods for classifying populations including alzheimer's disease populations
JP6143233B2 (ja) * 2015-08-05 2017-06-07 国立大学法人京都大学 運動ニューロン疾患の検査方法及び治療剤のスクリーニング方法
EP3410926A4 (en) 2016-02-01 2019-08-28 The Board of Trustees of the Leland Stanford Junior University METHOD AND SYSTEMS FOR ANALYZING FUNCTIONAL IMAGING DATA
JP6839342B2 (ja) 2016-09-16 2021-03-10 富士通株式会社 情報処理装置、情報処理方法およびプログラム
JP6837493B2 (ja) 2016-12-06 2021-03-03 富士フイルム株式会社 細胞画像評価装置および細胞画像評価制御プログラム
CN120636518A (zh) 2017-05-12 2025-09-12 密歇根大学董事会 个体和队列药理学表型预测平台
WO2018211687A1 (ja) * 2017-05-19 2018-11-22 株式会社オプティム コンピュータシステム、被験者診断方法及び支援プログラム
JPWO2018216705A1 (ja) * 2017-05-23 2020-03-26 国立大学法人京都大学 神経変性疾患の予防及び／又は治療剤
JP2019103293A (ja) 2017-12-05 2019-06-24 マブチモーター株式会社 モータ
WO2020118158A1 (en) 2018-12-07 2020-06-11 President And Fellows Of Harvard College Drug discovery and early disease identification platform using electronic health records, genetics and stem cells
JPWO2020241772A1 (https=) 2019-05-31 2020-12-03

Also Published As

Publication number Publication date
EP3978595A1 (en) 2022-04-06
EP3978595A4 (en) 2023-07-05
JPWO2020241772A1 (https=) 2020-12-03
US12462378B2 (en) 2025-11-04
US20220215543A1 (en) 2022-07-07
WO2020241772A1 (ja) 2020-12-03

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