SG11202112726SA - Stable formulations of recombinant proteins - Google Patents

Stable formulations of recombinant proteins

Info

Publication number
SG11202112726SA
SG11202112726SA SG11202112726SA SG11202112726SA SG11202112726SA SG 11202112726S A SG11202112726S A SG 11202112726SA SG 11202112726S A SG11202112726S A SG 11202112726SA SG 11202112726S A SG11202112726S A SG 11202112726SA SG 11202112726S A SG11202112726S A SG 11202112726SA
Authority
SG
Singapore
Prior art keywords
recombinant proteins
stable formulations
formulations
stable
recombinant
Prior art date
Application number
SG11202112726SA
Inventor
Dhananjay Sathe
Bijay Padhi
Vivek Mishra
Anupam Jain
Original Assignee
Unichem Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unichem Lab Ltd filed Critical Unichem Lab Ltd
Publication of SG11202112726SA publication Critical patent/SG11202112726SA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
SG11202112726SA 2019-07-09 2020-07-07 Stable formulations of recombinant proteins SG11202112726SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201921027358 2019-07-09
PCT/IB2020/056361 WO2021005500A1 (en) 2019-07-09 2020-07-07 Stable formulations of recombinant proteins

Publications (1)

Publication Number Publication Date
SG11202112726SA true SG11202112726SA (en) 2021-12-30

Family

ID=72046948

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202112726SA SG11202112726SA (en) 2019-07-09 2020-07-07 Stable formulations of recombinant proteins

Country Status (12)

Country Link
US (1) US20220339241A1 (en)
EP (1) EP3996680A1 (en)
JP (1) JP2022539494A (en)
KR (1) KR20220034053A (en)
CN (1) CN114126584A (en)
AU (1) AU2020311050A1 (en)
BR (1) BR112021023265A2 (en)
CA (1) CA3140609A1 (en)
MX (1) MX2021015426A (en)
SG (1) SG11202112726SA (en)
WO (1) WO2021005500A1 (en)
ZA (1) ZA202109011B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021005416A (en) * 2018-11-19 2021-07-06 Unichem Lab Ltd Combination of chemotherapy with recombinant s. rolfsii lectin.
KR20240040820A (en) 2021-07-08 2024-03-28 유니켐 레버러토리스 리미티드 Recombinant proteins, compositions and methods for stabilizing the same
CA3227834A1 (en) 2021-08-30 2023-03-09 Dhananjay Sathe Protein compositions for the treatment of inflammatory diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011573A (en) 2001-07-23 2007-08-08 纳蒂芒公司 Production of high molecular mass lectins
WO2003018617A1 (en) 2001-08-31 2003-03-06 Fuso Pharmaceutical Industries, Ltd. Method of purifying human mannose binding lectin, human mannose binding lectin compositions and medicinal use of human mannose binding lectin
NZ535600A (en) 2002-04-24 2008-03-28 Queensland Inst Med Res MASP-depleted MBL compositions are superior at activating the complement cascade when compared with MBL purified in complex with its associated MASPs
JP4852703B2 (en) 2004-08-27 2012-01-11 国立大学法人 新潟大学 Brain tumor detection method and brain tumor detection substance used therefor
CN101485880A (en) 2008-01-15 2009-07-22 上海新生源医药研究有限公司 Pharmaceutical composition for treating immunodeficiency symptoms
LT3418296T (en) 2009-02-18 2024-10-10 Unichem Laboratories Limited Cancer cell binding recombinant lectins with antitumor activity and method of preparation
WO2014203261A2 (en) 2010-02-02 2014-12-24 Unichem Laboratories Ltd. Recombinant lectin and method of preparing thereof
EP2508195A1 (en) 2011-04-06 2012-10-10 Cytavis BioPharma GmbH Medicine containing recombinant mistellectins for treating malignant melanoma
SG11201500632VA (en) 2012-08-14 2015-02-27 Univ Nanyang Tech Anti-viral methods and the use of an anti-viral agent
WO2016178996A1 (en) * 2015-05-01 2016-11-10 The Regents Of The University Of California Glycan-dependent immunotherapeutic molecules
RU2644332C1 (en) 2016-12-30 2018-02-08 Общество с ограниченной ответственностью научно-технический центр "БиоКлиникум" (ООО НТЦ "БиоКлиникум") Method for obtaining a vegetable ml1 lecture from a missile white and a pharmaceutical composition on its basis (variants)
SG11202101391WA (en) 2018-08-31 2021-03-30 Unichem Lab Ltd Recombinant lectin variants
MX2021005416A (en) * 2018-11-19 2021-07-06 Unichem Lab Ltd Combination of chemotherapy with recombinant s. rolfsii lectin.

Also Published As

Publication number Publication date
JP2022539494A (en) 2022-09-12
US20220339241A1 (en) 2022-10-27
EP3996680A1 (en) 2022-05-18
AU2020311050A1 (en) 2021-12-23
BR112021023265A2 (en) 2022-03-08
ZA202109011B (en) 2022-07-27
MX2021015426A (en) 2022-01-24
CA3140609A1 (en) 2021-01-14
CN114126584A (en) 2022-03-01
WO2021005500A1 (en) 2021-01-14
KR20220034053A (en) 2022-03-17

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