SG11202111066UA - High density lipoprotein nanoparticles and rna templated lipoprotein particles for ocular therapy - Google Patents
High density lipoprotein nanoparticles and rna templated lipoprotein particles for ocular therapyInfo
- Publication number
- SG11202111066UA SG11202111066UA SG11202111066UA SG11202111066UA SG11202111066UA SG 11202111066U A SG11202111066U A SG 11202111066UA SG 11202111066U A SG11202111066U A SG 11202111066UA SG 11202111066U A SG11202111066U A SG 11202111066UA SG 11202111066U A SG11202111066U A SG 11202111066UA
- Authority
- SG
- Singapore
- Prior art keywords
- lipoprotein
- high density
- nanoparticles
- ocular therapy
- particles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6917—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a lipoprotein vesicle, e.g. HDL or LDL proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1275—Lipoproteins; Chylomicrons; Artificial HDL, LDL, VLDL, protein-free species thereof; Precursors thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962839579P | 2019-04-26 | 2019-04-26 | |
PCT/US2020/029752 WO2020219833A1 (en) | 2019-04-26 | 2020-04-24 | High density lipoprotein nanoparticles and rna templated lipoprotein particles for ocular therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202111066UA true SG11202111066UA (en) | 2021-11-29 |
Family
ID=72940657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202111066UA SG11202111066UA (en) | 2019-04-26 | 2020-04-24 | High density lipoprotein nanoparticles and rna templated lipoprotein particles for ocular therapy |
Country Status (9)
Country | Link |
---|---|
US (1) | US20220211633A1 (zh) |
EP (1) | EP3958843A4 (zh) |
JP (1) | JP2022529506A (zh) |
CN (1) | CN113939278A (zh) |
AU (1) | AU2020261414A1 (zh) |
CA (1) | CA3137565A1 (zh) |
MX (1) | MX2021013068A (zh) |
SG (1) | SG11202111066UA (zh) |
WO (1) | WO2020219833A1 (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011091065A2 (en) | 2010-01-19 | 2011-07-28 | Northwestern University | Synthetic nanostructures including nucleic acids and/or other entities |
AU2022296780A1 (en) * | 2021-06-22 | 2023-12-07 | Bio-Trip B.V. | Nucleic acid containing nanoparticles |
KR20240037272A (ko) * | 2021-07-09 | 2024-03-21 | 주식회사 루카에이아이셀 | 건조 예방, 개선 또는 치료를 위한 지질 혼합물을 함유하는 점안액 및 이의 제조방법 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090110739A1 (en) * | 2007-05-15 | 2009-04-30 | University Of North Texas Health Science Center At Forth Worth | Targeted cancer chemotherapy using synthetic nanoparticles |
JP5539962B2 (ja) * | 2008-04-25 | 2014-07-02 | ノースウェスタン、ユニバーシティ | コレステロールを隔離するのに適したナノ構造体 |
WO2011091065A2 (en) * | 2010-01-19 | 2011-07-28 | Northwestern University | Synthetic nanostructures including nucleic acids and/or other entities |
WO2012078558A2 (en) * | 2010-12-06 | 2012-06-14 | Rush University Medical Center | microRNAs AS NEW THERAPEUTIC TARGETS FOR THE PREVENTION AND/OR TREATMENT OF RETINOPATHY |
CA2865279C (en) * | 2012-02-22 | 2023-04-25 | Northwestern University | Nanostructures for treating cancers and other conditions |
EP3238746B1 (en) * | 2014-12-25 | 2023-12-20 | Kyoto University | High-density lipoprotein, and delivery of drug to posterior segment of eye by ocular instillation of said cytophilic peptide-fused high-density lipoprotein |
US20170165200A1 (en) * | 2015-11-20 | 2017-06-15 | University Of North Texas Health Science Center | Composition of lipid-based nanoparticles for small molecules and macromolecules |
US10967072B2 (en) * | 2016-04-27 | 2021-04-06 | Northwestern University | Short interfering RNA templated lipoprotein particles (siRNA-TLP) |
CN110087638A (zh) * | 2016-12-14 | 2019-08-02 | 中国医药大学 | 微小rna-195组合物及其在眼科疾病中的应用 |
-
2020
- 2020-04-24 WO PCT/US2020/029752 patent/WO2020219833A1/en unknown
- 2020-04-24 AU AU2020261414A patent/AU2020261414A1/en not_active Abandoned
- 2020-04-24 EP EP20794209.5A patent/EP3958843A4/en not_active Withdrawn
- 2020-04-24 US US17/605,510 patent/US20220211633A1/en active Pending
- 2020-04-24 MX MX2021013068A patent/MX2021013068A/es unknown
- 2020-04-24 CN CN202080030991.1A patent/CN113939278A/zh active Pending
- 2020-04-24 CA CA3137565A patent/CA3137565A1/en active Pending
- 2020-04-24 JP JP2021563014A patent/JP2022529506A/ja active Pending
- 2020-04-24 SG SG11202111066UA patent/SG11202111066UA/en unknown
Also Published As
Publication number | Publication date |
---|---|
MX2021013068A (es) | 2022-01-24 |
WO2020219833A1 (en) | 2020-10-29 |
CN113939278A (zh) | 2022-01-14 |
EP3958843A4 (en) | 2023-02-22 |
US20220211633A1 (en) | 2022-07-07 |
EP3958843A1 (en) | 2022-03-02 |
CA3137565A1 (en) | 2020-10-29 |
AU2020261414A1 (en) | 2021-11-04 |
JP2022529506A (ja) | 2022-06-22 |
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