SG11202110836SA - Peptides and compounds that bind to elongation initiation factor 4e - Google Patents

Peptides and compounds that bind to elongation initiation factor 4e

Info

Publication number
SG11202110836SA
SG11202110836SA SG11202110836SA SG11202110836SA SG11202110836SA SG 11202110836S A SG11202110836S A SG 11202110836SA SG 11202110836S A SG11202110836S A SG 11202110836SA SG 11202110836S A SG11202110836S A SG 11202110836SA SG 11202110836S A SG11202110836S A SG 11202110836SA
Authority
SG
Singapore
Prior art keywords
peptides
bind
compounds
initiation factor
elongation initiation
Prior art date
Application number
SG11202110836SA
Inventor
Simon Ng
Christopher John Brown
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of SG11202110836SA publication Critical patent/SG11202110836SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202110836SA 2019-03-29 2020-03-30 Peptides and compounds that bind to elongation initiation factor 4e SG11202110836SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201902892R 2019-03-29
PCT/SG2020/050192 WO2020204828A1 (en) 2019-03-29 2020-03-30 Peptides and compounds that bind to elongation initiation factor 4e

Publications (1)

Publication Number Publication Date
SG11202110836SA true SG11202110836SA (en) 2021-10-28

Family

ID=72667485

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110836SA SG11202110836SA (en) 2019-03-29 2020-03-30 Peptides and compounds that bind to elongation initiation factor 4e

Country Status (5)

Country Link
US (1) US20220242906A1 (en)
EP (1) EP3947416A4 (en)
CN (1) CN113646325A (en)
SG (1) SG11202110836SA (en)
WO (1) WO2020204828A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023069332A1 (en) * 2021-10-22 2023-04-27 Merck Sharp & Dohme Llc Cell permeable macrocyclic peptides useful for eif4e cap-binding site inhibition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6020162A (en) * 1997-06-13 2000-02-01 The Rockefeller University Crystal of a protein-ligand complex containing an N-terminal truncated eIF4E, and methods of use thereof
CN1339492A (en) * 2000-08-23 2002-03-13 上海博德基因开发有限公司 New polypeptide-human translation initiation factor subunit eIF4E binding protein 17.27 and polynucleotide for encoding such polypeptide
US20110319338A1 (en) * 2008-12-18 2011-12-29 The Board Of Regents Of The University Of Texas System Peptides that bind eukaryotic translation initiation factor 4e
FR2942798B1 (en) * 2009-03-05 2011-04-08 Centre Nat Rech Scient PEPTIDES USEFUL FOR THE TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA
WO2010138084A1 (en) * 2009-05-28 2010-12-02 Agency For Science, Technology And Research CRYSTAL STRUCTURE OF CAP-FREE HUMAN eIF4E
US9018348B2 (en) * 2010-04-27 2015-04-28 Agency For Science, Technology And Research eIF4E binding peptides
EP2870174A1 (en) * 2012-07-09 2015-05-13 F. Hoffmann-La Roche AG Cell penetrating peptides to target eif4e
EP2976354A4 (en) * 2013-03-21 2016-10-26 Agency Science Tech & Res STAPLING eIF4E INTERACTING PEPTIDES
WO2018073394A1 (en) * 2016-10-19 2018-04-26 Cellectis Cell death inducing chimeric antigen receptors

Also Published As

Publication number Publication date
CN113646325A (en) 2021-11-12
EP3947416A4 (en) 2023-05-31
US20220242906A1 (en) 2022-08-04
WO2020204828A1 (en) 2020-10-08
EP3947416A1 (en) 2022-02-09

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