SG11202110469PA - Ghrh or analogues thereof for use in treatment of hepatic disease - Google Patents

Ghrh or analogues thereof for use in treatment of hepatic disease

Info

Publication number
SG11202110469PA
SG11202110469PA SG11202110469PA SG11202110469PA SG11202110469PA SG 11202110469P A SG11202110469P A SG 11202110469PA SG 11202110469P A SG11202110469P A SG 11202110469PA SG 11202110469P A SG11202110469P A SG 11202110469PA SG 11202110469P A SG11202110469P A SG 11202110469PA
Authority
SG
Singapore
Prior art keywords
pharmaceutically acceptable
hexenoyl
acceptable salt
subject
trans
Prior art date
Application number
SG11202110469PA
Other languages
English (en)
Inventor
Steven K Grinspoon
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of SG11202110469PA publication Critical patent/SG11202110469PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/25Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202110469PA 2019-03-29 2020-03-27 Ghrh or analogues thereof for use in treatment of hepatic disease SG11202110469PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962826284P 2019-03-29 2019-03-29
US201962861187P 2019-06-13 2019-06-13
PCT/US2020/025180 WO2020205498A1 (en) 2019-03-29 2020-03-27 Ghrh or analogues thereof for use in treatment of hepatic disease

Publications (1)

Publication Number Publication Date
SG11202110469PA true SG11202110469PA (en) 2021-10-28

Family

ID=72607731

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110469PA SG11202110469PA (en) 2019-03-29 2020-03-27 Ghrh or analogues thereof for use in treatment of hepatic disease

Country Status (10)

Country Link
US (4) US10799562B1 (https=)
EP (1) EP3947426A4 (https=)
JP (1) JP2022527190A (https=)
KR (1) KR20210145226A (https=)
CN (1) CN113646327A (https=)
AU (1) AU2020253828A1 (https=)
CA (1) CA3133319A1 (https=)
IL (1) IL286703A (https=)
SG (1) SG11202110469PA (https=)
WO (1) WO2020205498A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202110469PA (en) 2019-03-29 2021-10-28 Massachusetts Gen Hospital Ghrh or analogues thereof for use in treatment of hepatic disease
CN115884783A (zh) * 2020-07-05 2023-03-31 瑟瑞技术公司 Ghrh类似物的低剂量药物组合物及其用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101678083A (zh) * 2007-04-04 2010-03-24 瑟瑞技术公司 Ghrh分子的药物制剂
US9163091B2 (en) * 2007-05-30 2015-10-20 Lpath, Inc. Compositions and methods for binding lysophosphatidic acid
US20150174207A1 (en) * 2013-12-24 2015-06-25 University Of Miami Methods for treating cancer with ghrh agonists
US20170105996A1 (en) * 2015-10-16 2017-04-20 Teva Pharmaceutical Industries, Ltd. Treatment of non-alcoholic fatty liver disease or non-alcoholic steatohepatitis with delayed-release 6-mercaptopurine
WO2017181277A1 (en) * 2016-04-19 2017-10-26 Griffon Pharmaceuticals Inc. Pegylated bioactive peptides and uses thereof
KR20200121308A (ko) * 2018-02-14 2020-10-23 루모스 파마, 인크. 비알코올성 지방간 질환 및 비알코올성 지방간염 치료용 조성물
SG11202110469PA (en) * 2019-03-29 2021-10-28 Massachusetts Gen Hospital Ghrh or analogues thereof for use in treatment of hepatic disease
WO2022093757A1 (en) * 2020-10-30 2022-05-05 The General Hospital Corporation Kits, reagents and methods for the assessment of liver diseases
US20220152012A1 (en) * 2020-11-16 2022-05-19 The Regents Of The University Of California Methods for regressing or reversing fibrosis and/or liver cirrhosis in a subject in need thereof using high-dose niacin, or a niacin analog thereof

Also Published As

Publication number Publication date
US10946073B2 (en) 2021-03-16
US11738066B2 (en) 2023-08-29
US10799562B1 (en) 2020-10-13
EP3947426A4 (en) 2023-01-04
WO2020205498A1 (en) 2020-10-08
EP3947426A1 (en) 2022-02-09
JP2022527190A (ja) 2022-05-31
US20240091316A1 (en) 2024-03-21
KR20210145226A (ko) 2021-12-01
US20200405816A1 (en) 2020-12-31
CN113646327A (zh) 2021-11-12
AU2020253828A1 (en) 2021-10-28
US12233107B2 (en) 2025-02-25
IL286703A (en) 2021-10-31
US20210177943A1 (en) 2021-06-17
US20200306345A1 (en) 2020-10-01
CA3133319A1 (en) 2020-10-08

Similar Documents

Publication Publication Date Title
EP3412310B1 (en) Pharmaceutical formulations of tnf-alpha antibodies
CN102389413B (zh) 用于治疗糖尿病的组合物及其应用
US12233107B2 (en) GHRH or analogues thereof for use in treatment of hepatic disease
TR201906843T4 (tr) Hızlı etkili insülin bileşimleri.
EP2209528A1 (en) Rapid acting injectable insulin compositions
US20050112093A1 (en) Combination therapy for HCV infection
JP7738046B2 (ja) 組換えヒト副甲状腺ホルモンの安定性を向上させるための製剤
WO2018171557A1 (zh) 一种长效化突变的人源成纤维生长因子的新用途
JP2011506436A (ja) 細胞傷害性tリンパ球抗原4(ctla4)に対する抗体と組み合わせられたアルファチモシンペプチドによる黒色腫の処置の方法
KR20240176455A (ko) 시클로덱스트린을 포함하는 약학적 제형
US12564619B2 (en) Stable formulations of recombinant proteins
EP3856767B1 (en) Formulations of glucagon-like-peptide-2 (glp-2) analogues
US20200197494A1 (en) Peptide compositions and methods of use
EP4643862A1 (en) Pharmaceutical composition and use thereof
US20130079416A1 (en) Homeopathic medicament comprising phenacetin for the treatment of cancer
CN117018197A (zh) 促进dock11表达的试剂作为治疗神经病理性疼痛药物的应用
CN116407614A (zh) 一种新型三激动剂创新生物药物的稳定制剂
CN115884783A (zh) Ghrh类似物的低剂量药物组合物及其用途
HK40050341A (en) Formulations for improved stability of recombinant human parathyroid hormone