SG11202108940RA - Novel heterotricyclic derivative compound and use of same - Google Patents

Novel heterotricyclic derivative compound and use of same

Info

Publication number
SG11202108940RA
SG11202108940RA SG11202108940RA SG11202108940RA SG11202108940RA SG 11202108940R A SG11202108940R A SG 11202108940RA SG 11202108940R A SG11202108940R A SG 11202108940RA SG 11202108940R A SG11202108940R A SG 11202108940RA SG 11202108940R A SG11202108940R A SG 11202108940RA
Authority
SG
Singapore
Prior art keywords
same
derivative compound
heterotricyclic
novel
novel heterotricyclic
Prior art date
Application number
SG11202108940RA
Other languages
English (en)
Inventor
Dong Jin Hong
Seung Hyun Jung
Chang Hee Park
Seo Hee Kim
Ji Young Hwang
Young Gil Ahn
Original Assignee
Hanmi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharmaceutical Co Ltd filed Critical Hanmi Pharmaceutical Co Ltd
Publication of SG11202108940RA publication Critical patent/SG11202108940RA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/056Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4743Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11202108940RA 2019-02-19 2020-02-19 Novel heterotricyclic derivative compound and use of same SG11202108940RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020190019544A KR20200101219A (ko) 2019-02-19 2019-02-19 신규한 헤테로트리시클릭 유도체 화합물 및 이의 용도
PCT/KR2020/002427 WO2020171606A1 (ko) 2019-02-19 2020-02-19 신규한 헤테로트리시클릭 유도체 화합물 및 이의 용도

Publications (1)

Publication Number Publication Date
SG11202108940RA true SG11202108940RA (en) 2021-09-29

Family

ID=72144293

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202108940RA SG11202108940RA (en) 2019-02-19 2020-02-19 Novel heterotricyclic derivative compound and use of same

Country Status (17)

Country Link
US (1) US20220135582A1 (zh)
EP (1) EP3929199A4 (zh)
JP (1) JP7358491B2 (zh)
KR (1) KR20200101219A (zh)
CN (1) CN113423710A (zh)
AU (1) AU2020226042B2 (zh)
BR (1) BR112021016448A2 (zh)
CA (1) CA3130456C (zh)
CL (1) CL2021002165A1 (zh)
EA (1) EA202191991A1 (zh)
IL (1) IL285604A (zh)
MX (1) MX2021009854A (zh)
PE (1) PE20211703A1 (zh)
SG (1) SG11202108940RA (zh)
TW (1) TWI829869B (zh)
WO (1) WO2020171606A1 (zh)
ZA (1) ZA202105970B (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3100977A1 (en) 2018-05-21 2019-11-28 Constellation Pharmaceuticals, Inc. Modulators of methyl modifying enzymes, compositions and uses thereof
KR102386403B1 (ko) * 2020-08-13 2022-04-15 한미약품 주식회사 신규한 디옥솔로이소퀴놀린온 유도체 화합물 및 이의 용도
EP4196483A1 (en) * 2020-08-13 2023-06-21 Hanmi Pharmaceutical Co., Ltd. Novel dioxoloisoquinolinone derivatives and use thereof
WO2022179584A1 (zh) * 2021-02-26 2022-09-01 南京药石科技股份有限公司 新型ezh2抑制剂及其用途
WO2023217018A1 (zh) * 2022-05-07 2023-11-16 贝达药业股份有限公司 Ezh2抑制剂及其在医药上的应用
TW202400602A (zh) * 2022-05-31 2024-01-01 大陸商和記黃埔醫藥(上海)有限公司 三環類化合物及其用途
WO2023244918A1 (en) 2022-06-13 2023-12-21 Treeline Biosciences, Inc. Quinolone bcl6 bifunctional degraders
WO2023244917A1 (en) 2022-06-13 2023-12-21 Treeline Biosciences, Inc. 1,8-naphthyridin-2-one heterobifunctional bcl6 degraders
WO2024038115A1 (en) 2022-08-17 2024-02-22 Morphosys Ag Therapy comprising anti-cd19 antibody and ezh2 modulators
CN115974856B (zh) * 2022-12-28 2023-08-11 北京康立生医药技术开发有限公司 一种治疗成人t细胞白血病淋巴瘤药物伐美妥司他的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3438B1 (ar) 2011-04-13 2019-10-20 Epizyme Inc مركبات بنزين مستبدلة بأريل أو أريل غير متجانس
WO2013067302A1 (en) * 2011-11-04 2013-05-10 Glaxosmithkline Intellectual Property (No. 2) Limited Method of treatment
UA111305C2 (uk) * 2012-12-21 2016-04-11 Пфайзер Інк. Конденсовані лактами арилу та гетероарилу
WO2015077194A1 (en) * 2013-11-22 2015-05-28 Bristol-Myers Squibb Company Inhibitors of lysine methyl transferase
PL3121175T3 (pl) * 2014-03-17 2020-06-01 Daiichi Sankyo Company, Limited Pochodne 1,3-benzodioksolu jako inhibitory ezh1 i/lub ezh2
WO2015193768A1 (en) 2014-06-17 2015-12-23 Pfizer Inc. Aryl fused lactams as ezh2 modulators
MD4820C1 (ro) * 2014-06-17 2023-03-31 Pfizer Inc. Compuşi dihidroizochinolinonici substituiţi
WO2016154434A1 (en) 2015-03-25 2016-09-29 The Regents Of The University Of California Selective alpha-7 nicotinic receptor agonists and methods for making and using them
CA3100977A1 (en) * 2018-05-21 2019-11-28 Constellation Pharmaceuticals, Inc. Modulators of methyl modifying enzymes, compositions and uses thereof

Also Published As

Publication number Publication date
MX2021009854A (es) 2021-09-28
PE20211703A1 (es) 2021-09-01
AU2020226042B2 (en) 2022-07-14
JP2022522648A (ja) 2022-04-20
KR20200101219A (ko) 2020-08-27
US20220135582A1 (en) 2022-05-05
EP3929199A4 (en) 2022-10-26
EA202191991A1 (ru) 2021-12-10
CA3130456A1 (en) 2020-08-27
WO2020171606A1 (ko) 2020-08-27
CN113423710A (zh) 2021-09-21
BR112021016448A2 (pt) 2021-11-09
AU2020226042A1 (en) 2021-09-09
IL285604A (en) 2021-09-30
CA3130456C (en) 2023-10-03
TWI829869B (zh) 2024-01-21
CL2021002165A1 (es) 2022-04-22
TW202045512A (zh) 2020-12-16
EP3929199A1 (en) 2021-12-29
ZA202105970B (en) 2023-05-31
JP7358491B2 (ja) 2023-10-10

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