SG11202107126YA - Magnetic resonance imaging drug containing a deuterated natural branched-chain amino acid, and diagnostic method using said drug - Google Patents

Magnetic resonance imaging drug containing a deuterated natural branched-chain amino acid, and diagnostic method using said drug

Info

Publication number
SG11202107126YA
SG11202107126YA SG11202107126YA SG11202107126YA SG11202107126YA SG 11202107126Y A SG11202107126Y A SG 11202107126YA SG 11202107126Y A SG11202107126Y A SG 11202107126YA SG 11202107126Y A SG11202107126Y A SG 11202107126YA SG 11202107126Y A SG11202107126Y A SG 11202107126YA
Authority
SG
Singapore
Prior art keywords
drug
deuterated
amino acid
magnetic resonance
resonance imaging
Prior art date
Application number
SG11202107126YA
Other languages
English (en)
Inventor
Aleksei Valerevich Lesiv
Pavel Evgenevich Ivashkin
Aleksei Viktorovich Kosenkov
Vladimir Ivanovich Polshakov
Mikhail Valentinovich Kiselevskii
Boris Natanovich Korol'
Original Assignee
Llc Solvex Solvex Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Llc Solvex Solvex Llc filed Critical Llc Solvex Solvex Llc
Publication of SG11202107126YA publication Critical patent/SG11202107126YA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/465—NMR spectroscopy applied to biological material, e.g. in vitro testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
SG11202107126YA 2018-12-29 2019-05-08 Magnetic resonance imaging drug containing a deuterated natural branched-chain amino acid, and diagnostic method using said drug SG11202107126YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2018147615A RU2738850C2 (ru) 2018-12-29 2018-12-29 Препарат для магнитно-резонансной томографии, содержащий дейтерированную природную аминокислоту с разветвленной боковой цепью, и способ диагностики с использованием этого препарата
PCT/RU2019/000324 WO2020139126A1 (ru) 2018-12-29 2019-05-08 Препарат для магнитно-резонансной томографии, содержащий дейтерированную природную аминокислоту с разветвленной боковой цепью, и способ диагностики с использованием этого препарата

Publications (1)

Publication Number Publication Date
SG11202107126YA true SG11202107126YA (en) 2021-07-29

Family

ID=71127394

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202107126YA SG11202107126YA (en) 2018-12-29 2019-05-08 Magnetic resonance imaging drug containing a deuterated natural branched-chain amino acid, and diagnostic method using said drug

Country Status (8)

Country Link
US (1) US20220072162A1 (zh)
EP (1) EP3903831A4 (zh)
JP (1) JP2022515892A (zh)
CN (1) CN113518629B (zh)
IL (1) IL284431A (zh)
RU (1) RU2738850C2 (zh)
SG (1) SG11202107126YA (zh)
WO (1) WO2020139126A1 (zh)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5042488A (en) 1987-09-29 1991-08-27 The Washington University Methods employing deuterium for obtaining direct, observable deuterium magnetic resonance images in vivo and in situ
US6574496B1 (en) * 1999-05-19 2003-06-03 Amersham Health As Magnetic resonance imaging
US20030211036A1 (en) 2002-05-07 2003-11-13 Hadassa Degani Method and apparatus for monitoring and quantitatively evaluating tumor perfusion
US10646594B2 (en) * 2009-06-19 2020-05-12 Case Western Reserve University Deuterated metabolic water precursor for detecting and treating diseased tissue
RU2663286C1 (ru) * 2017-11-21 2018-08-03 Общество с ограниченной ответственностью "Сольвекс" Препарат для магнитно-резонансной диагностики онкологических заболеваний, содержащий дейтерированную 2-амино-2-метилпропионовую кислоту и/или 2-(n-метиламино)-2-метилпропионовую кислоту, и способ диагностики с использованием этого препарата

Also Published As

Publication number Publication date
RU2018147615A3 (zh) 2020-06-29
IL284431A (en) 2021-08-31
EP3903831A1 (en) 2021-11-03
US20220072162A1 (en) 2022-03-10
CN113518629A (zh) 2021-10-19
WO2020139126A1 (ru) 2020-07-02
EP3903831A4 (en) 2023-01-11
RU2018147615A (ru) 2020-06-29
RU2738850C2 (ru) 2020-12-17
CN113518629B (zh) 2024-03-08
JP2022515892A (ja) 2022-02-22

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