SG11202106896TA - 3-carbonylamino-5-cyclopentyl-1h-pyrazole compounds having inhibitory activity on cdk2 - Google Patents
3-carbonylamino-5-cyclopentyl-1h-pyrazole compounds having inhibitory activity on cdk2Info
- Publication number
- SG11202106896TA SG11202106896TA SG11202106896TA SG11202106896TA SG11202106896TA SG 11202106896T A SG11202106896T A SG 11202106896TA SG 11202106896T A SG11202106896T A SG 11202106896TA SG 11202106896T A SG11202106896T A SG 11202106896TA SG 11202106896T A SG11202106896T A SG 11202106896TA
- Authority
- SG
- Singapore
- Prior art keywords
- cdk2
- carbonylamino
- cyclopentyl
- inhibitory activity
- pyrazole compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962799455P | 2019-01-31 | 2019-01-31 | |
US202062959042P | 2020-01-09 | 2020-01-09 | |
PCT/IB2020/050653 WO2020157652A2 (en) | 2019-01-31 | 2020-01-28 | Cdk2 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202106896TA true SG11202106896TA (en) | 2021-08-30 |
Family
ID=69467606
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202106896TA SG11202106896TA (en) | 2019-01-31 | 2020-01-28 | 3-carbonylamino-5-cyclopentyl-1h-pyrazole compounds having inhibitory activity on cdk2 |
Country Status (23)
Country | Link |
---|---|
US (3) | US11014911B2 (en) |
EP (1) | EP3917913A2 (en) |
JP (2) | JP7094456B2 (en) |
KR (1) | KR20210121186A (en) |
CN (1) | CN113330000A (en) |
AU (1) | AU2020213761C1 (en) |
BR (1) | BR112021012635A2 (en) |
CA (1) | CA3128155C (en) |
CL (1) | CL2021001991A1 (en) |
CO (1) | CO2021009806A2 (en) |
CR (1) | CR20210415A (en) |
CU (1) | CU20210065A7 (en) |
DO (1) | DOP2021000154A (en) |
EC (1) | ECSP21055158A (en) |
IL (1) | IL284589A (en) |
MA (1) | MA54859A (en) |
MX (1) | MX2021009276A (en) |
PE (1) | PE20212250A1 (en) |
PH (1) | PH12021551529A1 (en) |
SG (1) | SG11202106896TA (en) |
TW (1) | TWI738197B (en) |
UY (1) | UY38553A (en) |
WO (1) | WO2020157652A2 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113330000A (en) * | 2019-01-31 | 2021-08-31 | 辉瑞公司 | 3-carbonylamino-5-cyclopentyl-1 FI-pyrrole compound having inhibitory activity against CDK2 |
EP4181919A1 (en) * | 2020-07-20 | 2023-05-24 | Pfizer Inc. | Combination therapy |
WO2022018667A1 (en) | 2020-07-24 | 2022-01-27 | Pfizer Inc. | Combination therapies using cdk2 and cdc25a inhibitors |
TW202237585A (en) | 2020-11-27 | 2022-10-01 | 瑞士商瑞森製藥公司 | Cdk inhibitors |
TW202229268A (en) * | 2020-12-22 | 2022-08-01 | 大陸商上海拓界生物醫藥科技有限公司 | Cdk2 inhibitor and preparation method thereof |
WO2022135365A1 (en) * | 2020-12-22 | 2022-06-30 | Anrui Biomedical Technology (Guangzhou) Co., Ltd. | Disubstituted cyclopentane kinase inhibitors |
MX2023007699A (en) | 2020-12-24 | 2023-07-10 | Pfizer | Solid forms of a cdk2 inhibitor. |
WO2022149057A1 (en) | 2021-01-05 | 2022-07-14 | Rhizen Pharmaceuticals Ag | Cdk inhibitors |
WO2022206888A1 (en) * | 2021-03-31 | 2022-10-06 | Qilu Regor Therapeutics Inc. | Cdk2 inhibitors and use thereof |
TW202309030A (en) * | 2021-05-07 | 2023-03-01 | 美商凱麥拉醫療公司 | Cdk2 degraders and uses thereof |
AR126251A1 (en) | 2021-06-28 | 2023-10-04 | Blueprint Medicines Corp | CDK2 INHIBITORS |
TW202317564A (en) * | 2021-07-01 | 2023-05-01 | 大陸商上海拓界生物醫藥科技有限公司 | Cdk2 inhibitor, a preparation method and a use thereof |
TW202330501A (en) * | 2021-10-05 | 2023-08-01 | 美商建南德克公司 | Cyclopentylpyrazole cdk2 inhibitors |
TW202325280A (en) * | 2021-11-09 | 2023-07-01 | 大陸商上海拓界生物醫藥科技有限公司 | An aminopyrazole derivative, preparation method and use thereof |
WO2023092088A1 (en) * | 2021-11-19 | 2023-05-25 | Blueprint Medicines Corporation | Cdk2 inhibitors and methods of making and using same |
WO2023100134A1 (en) | 2021-12-02 | 2023-06-08 | Pfizer Inc. | Methods and dosing regimens comprising a cdk2 inhibitor and a cdk4 inhibitor for treating cancer |
WO2023100131A1 (en) | 2021-12-02 | 2023-06-08 | Pfizer Inc. | Methods and dosing regimens comprising a cdk2 inhibitor for the treatment of cancer |
WO2023116884A1 (en) * | 2021-12-24 | 2023-06-29 | Qilu Regor Therapeutics Inc. | Cdk2 inhibitors and use thereof |
WO2023168686A1 (en) * | 2022-03-11 | 2023-09-14 | Qilu Regor Therapeutics Inc. | Substituted cyclopentanes as cdk2 inhibitors |
WO2023141852A1 (en) * | 2022-01-27 | 2023-08-03 | 益方生物科技(上海)股份有限公司 | Cdk2 inhibitors, preparation method therefor and use thereof |
WO2023160572A1 (en) * | 2022-02-24 | 2023-08-31 | 楚浦创制(武汉)医药科技有限公司 | Pyrazole derivative, pharmaceutical composition, and use |
TW202342002A (en) * | 2022-04-28 | 2023-11-01 | 大陸商正大天晴藥業集團股份有限公司 | Pyrazole-substituted cyclopentanol ester derivative and use thereof |
WO2023239629A1 (en) | 2022-06-06 | 2023-12-14 | Plexium, Inc. | Compounds and pharmaceutical compositions that degrade cdk2 |
WO2023244710A1 (en) * | 2022-06-16 | 2023-12-21 | Ensem Therapeutics, Inc. | Anilino-pyrazole derivatives, compositions and methods thereof |
WO2024035830A1 (en) * | 2022-08-11 | 2024-02-15 | Relay Therapeutics, Inc. | Solid forms of a cdk inhibitor |
WO2024046443A1 (en) * | 2022-09-01 | 2024-03-07 | Nutshell Biotech (Shanghai) Co., Ltd. | Macrocyclic compounds as selective cdk inhibitors |
WO2024056019A1 (en) * | 2022-09-15 | 2024-03-21 | Beigene, Ltd. | Bicyclic compounds as cdk inhibitors |
WO2024066981A1 (en) * | 2022-09-30 | 2024-04-04 | 楚浦创制(武汉)医药科技有限公司 | Deuterated pyrazole derivatives, pharmaceutical composition, use, and preparation method |
WO2024104455A1 (en) * | 2022-11-17 | 2024-05-23 | 山东绿叶制药有限公司 | Cdk2 inhibitor, preparation method therefor, and use thereof |
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US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
KR0166088B1 (en) | 1990-01-23 | 1999-01-15 | . | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
GB9518953D0 (en) | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
WO2000035298A1 (en) | 1996-11-27 | 2000-06-22 | Wm. Wrigley Jr. Company | Chewing gum containing medicament active agents |
GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
US20020103185A1 (en) | 2000-08-31 | 2002-08-01 | Sanner Mark A. | Pyrazole derivatives |
YU14703A (en) * | 2000-08-31 | 2006-05-25 | Pfizer Products Inc. | Pyrazole derivatives and their use as protein kinase inhibitors |
US7074809B2 (en) | 2002-08-09 | 2006-07-11 | Astrazeneca Ab | Compounds |
WO2004014370A2 (en) | 2002-08-09 | 2004-02-19 | Astrazeneca Ab | Oxadiazoles as modulators of metabotropic glutamate receptor-5 |
US7671072B2 (en) * | 2003-11-26 | 2010-03-02 | Pfizer Inc. | Aminopyrazole derivatives as GSK-3 inhibitors |
WO2005077368A2 (en) | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
WO2005077373A2 (en) | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
WO2005077345A1 (en) | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Compounds for the treatment of gastro-esophageal reflux disease |
BRPI0515571A (en) | 2004-09-23 | 2008-07-29 | Pfizer Prod Inc | thrombopoietin receptor agonists |
US9315449B2 (en) | 2008-05-15 | 2016-04-19 | Duke University | Substituted pyrazoles as heat shock transcription factor activators |
CN102088973A (en) | 2008-05-15 | 2011-06-08 | 杜克大学 | Compositions and methods relating to heat shock transcription factor activating compounds and targets thereof |
WO2012129562A2 (en) | 2011-03-24 | 2012-09-27 | The Scripps Research Institute | Compounds and methods for inducing chondrogenesis |
US8759380B2 (en) | 2011-04-22 | 2014-06-24 | Cytokinetics, Inc. | Certain heterocycles, compositions thereof, and methods for their use |
CN113330000A (en) * | 2019-01-31 | 2021-08-31 | 辉瑞公司 | 3-carbonylamino-5-cyclopentyl-1 FI-pyrrole compound having inhibitory activity against CDK2 |
-
2020
- 2020-01-28 CN CN202080011570.4A patent/CN113330000A/en active Pending
- 2020-01-28 CU CU2021000065A patent/CU20210065A7/en unknown
- 2020-01-28 US US16/774,786 patent/US11014911B2/en active Active
- 2020-01-28 MA MA054859A patent/MA54859A/en unknown
- 2020-01-28 CA CA3128155A patent/CA3128155C/en active Active
- 2020-01-28 BR BR112021012635A patent/BR112021012635A2/en unknown
- 2020-01-28 AU AU2020213761A patent/AU2020213761C1/en active Active
- 2020-01-28 CR CR20210415A patent/CR20210415A/en unknown
- 2020-01-28 WO PCT/IB2020/050653 patent/WO2020157652A2/en unknown
- 2020-01-28 SG SG11202106896TA patent/SG11202106896TA/en unknown
- 2020-01-28 KR KR1020217027618A patent/KR20210121186A/en not_active Application Discontinuation
- 2020-01-28 JP JP2021543997A patent/JP7094456B2/en active Active
- 2020-01-28 MX MX2021009276A patent/MX2021009276A/en unknown
- 2020-01-28 EP EP20703539.5A patent/EP3917913A2/en active Pending
- 2020-01-28 PE PE2021001227A patent/PE20212250A1/en unknown
- 2020-01-29 UY UY0001038553A patent/UY38553A/en unknown
- 2020-01-30 TW TW109102923A patent/TWI738197B/en active
-
2021
- 2021-04-20 US US17/235,836 patent/US11718603B2/en active Active
- 2021-04-20 US US17/235,846 patent/US11773082B2/en active Active
- 2021-06-25 PH PH12021551529A patent/PH12021551529A1/en unknown
- 2021-07-04 IL IL284589A patent/IL284589A/en unknown
- 2021-07-21 DO DO2021000154A patent/DOP2021000154A/en unknown
- 2021-07-26 EC ECSENADI202155158A patent/ECSP21055158A/en unknown
- 2021-07-26 CO CONC2021/0009806A patent/CO2021009806A2/en unknown
- 2021-07-29 CL CL2021001991A patent/CL2021001991A1/en unknown
-
2022
- 2022-06-21 JP JP2022099283A patent/JP2022120200A/en active Pending
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