SG11202106445RA - One pot synthesis of sets of oligonucleotides - Google Patents
One pot synthesis of sets of oligonucleotidesInfo
- Publication number
- SG11202106445RA SG11202106445RA SG11202106445RA SG11202106445RA SG11202106445RA SG 11202106445R A SG11202106445R A SG 11202106445RA SG 11202106445R A SG11202106445R A SG 11202106445RA SG 11202106445R A SG11202106445R A SG 11202106445RA SG 11202106445R A SG11202106445R A SG 11202106445RA
- Authority
- SG
- Singapore
- Prior art keywords
- oligonucleotides
- sets
- pot synthesis
- pot
- synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/10—Nucleotidyl transfering
- C12Q2521/101—DNA polymerase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19305007 | 2019-01-03 | ||
| PCT/EP2019/087048 WO2020141143A1 (en) | 2019-01-03 | 2019-12-26 | One pot synthesis of sets of oligonucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202106445RA true SG11202106445RA (en) | 2021-07-29 |
Family
ID=65200741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202106445RA SG11202106445RA (en) | 2019-01-03 | 2019-12-26 | One pot synthesis of sets of oligonucleotides |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220356510A1 (en) |
| EP (1) | EP3906317A1 (en) |
| JP (1) | JP7491934B2 (en) |
| KR (1) | KR20210111262A (en) |
| CN (1) | CN113272442B (en) |
| AU (1) | AU2019417966A1 (en) |
| CA (1) | CA3124763A1 (en) |
| IL (1) | IL284441A (en) |
| SG (1) | SG11202106445RA (en) |
| WO (1) | WO2020141143A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20220052938A (en) * | 2019-08-01 | 2022-04-28 | 디엔에이 스크립트 | Increased Long Sequence Yield in Template-Free Enzymatic Synthesis of Polynucleotides |
| JP2022549196A (en) | 2019-09-23 | 2022-11-24 | ディーエヌエー スクリプト | Increased Yields of Long Sequences in Templateless Enzymatic Synthesis of Polynucleotides |
| EP4182472A1 (en) | 2020-07-15 | 2023-05-24 | DNA Script | Massively parallel enzymatic synthesis of polynucleotides |
| CN117043171A (en) * | 2020-08-28 | 2023-11-10 | 特韦斯特生物科学公司 | Apparatus and method for synthesis |
| US20220195476A1 (en) * | 2020-12-21 | 2022-06-23 | Chen cheng yao | Method and kit for regenerating reusable initiators for nucleic acid synthesis |
Family Cites Families (57)
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| US5367066A (en) | 1984-10-16 | 1994-11-22 | Chiron Corporation | Oligonucleotides with selectably cleavable and/or abasic sites |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US4942124A (en) | 1987-08-11 | 1990-07-17 | President And Fellows Of Harvard College | Multiplex sequencing |
| US5168038A (en) | 1988-06-17 | 1992-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | In situ transcription in cells and tissues |
| CA2020958C (en) | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
| CA2044616A1 (en) | 1989-10-26 | 1991-04-27 | Roger Y. Tsien | Dna sequencing |
| US5126022A (en) | 1990-02-28 | 1992-06-30 | Soane Tecnologies, Inc. | Method and device for moving molecules by the application of a plurality of electrical fields |
| US6054034A (en) | 1990-02-28 | 2000-04-25 | Aclara Biosciences, Inc. | Acrylic microchannels and their use in electrophoretic applications |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| JP3080178B2 (en) | 1991-02-18 | 2000-08-21 | 東洋紡績株式会社 | Method for amplifying nucleic acid sequence and reagent kit therefor |
| US5981179A (en) | 1991-11-14 | 1999-11-09 | Digene Diagnostics, Inc. | Continuous amplification reaction |
| US5587128A (en) | 1992-05-01 | 1996-12-24 | The Trustees Of The University Of Pennsylvania | Mesoscale polynucleotide amplification devices |
| US5498392A (en) | 1992-05-01 | 1996-03-12 | Trustees Of The University Of Pennsylvania | Mesoscale polynucleotide amplification device and method |
| US5436143A (en) | 1992-12-23 | 1995-07-25 | Hyman; Edward D. | Method for enzymatic synthesis of oligonucleotides |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| EP0776330B1 (en) | 1994-06-23 | 2003-08-20 | Affymax Technologies N.V. | Photolabile compounds and methods for their use |
| US6001229A (en) | 1994-08-01 | 1999-12-14 | Lockheed Martin Energy Systems, Inc. | Apparatus and method for performing microfluidic manipulations for chemical analysis |
| US5763594A (en) | 1994-09-02 | 1998-06-09 | Andrew C. Hiatt | 3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds |
| US5808045A (en) | 1994-09-02 | 1998-09-15 | Andrew C. Hiatt | Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides |
| US5604097A (en) | 1994-10-13 | 1997-02-18 | Spectragen, Inc. | Methods for sorting polynucleotides using oligonucleotide tags |
| US5700642A (en) | 1995-05-22 | 1997-12-23 | Sri International | Oligonucleotide sizing using immobilized cleavable primers |
| US5830655A (en) | 1995-05-22 | 1998-11-03 | Sri International | Oligonucleotide sizing using cleavable primers |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| US6458530B1 (en) | 1996-04-04 | 2002-10-01 | Affymetrix Inc. | Selecting tag nucleic acids |
| ES2326050T5 (en) | 1996-06-04 | 2012-04-26 | University Of Utah Research Foundation | Hybridization monitoring during PCR |
| US6074827A (en) | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
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| US8574864B2 (en) * | 2009-11-05 | 2013-11-05 | Epicentre Technologies Corporation | Methods and kits for 3'-end-tagging of RNA |
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| FR3020071B1 (en) | 2014-04-17 | 2017-12-22 | Dna Script | PROCESS FOR THE SYNTHESIS OF NUCLEIC ACIDS, IN PARTICULAR LARGE NUCLEIC ACIDS, USE OF THE METHOD AND KIT FOR IMPLEMENTING THE METHOD |
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| FR3052462A1 (en) | 2016-06-14 | 2017-12-15 | Dna Script | POLYMERASE DNA VARIANTS OF THE POLX FAMILY |
| WO2018152323A1 (en) * | 2017-02-17 | 2018-08-23 | Camena Bioscience Limited | Compositions and methods for template-free enzymatic nucleic acid synthesis |
| WO2019051250A1 (en) | 2017-09-08 | 2019-03-14 | Sigma-Aldrich Co. Llc | Polymerase-mediated, template-independent polynucleotide synthesis |
| US10435676B2 (en) | 2018-01-08 | 2019-10-08 | Dna Script | Variants of terminal deoxynucleotidyl transferase and uses thereof |
-
2019
- 2019-12-26 EP EP19829643.6A patent/EP3906317A1/en active Pending
- 2019-12-26 CA CA3124763A patent/CA3124763A1/en active Pending
- 2019-12-26 WO PCT/EP2019/087048 patent/WO2020141143A1/en unknown
- 2019-12-26 KR KR1020217022202A patent/KR20210111262A/en active Search and Examination
- 2019-12-26 AU AU2019417966A patent/AU2019417966A1/en active Pending
- 2019-12-26 CN CN201980087736.8A patent/CN113272442B/en active Active
- 2019-12-26 SG SG11202106445RA patent/SG11202106445RA/en unknown
- 2019-12-26 US US17/419,637 patent/US20220356510A1/en active Pending
- 2019-12-26 JP JP2021538753A patent/JP7491934B2/en active Active
-
2021
- 2021-06-28 IL IL284441A patent/IL284441A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020141143A1 (en) | 2020-07-09 |
| KR20210111262A (en) | 2021-09-10 |
| JP2022515912A (en) | 2022-02-22 |
| CN113272442B (en) | 2024-03-15 |
| US20220356510A1 (en) | 2022-11-10 |
| CA3124763A1 (en) | 2020-07-09 |
| IL284441A (en) | 2021-08-31 |
| JP7491934B2 (en) | 2024-05-28 |
| EP3906317A1 (en) | 2021-11-10 |
| AU2019417966A1 (en) | 2021-07-08 |
| CN113272442A (en) | 2021-08-17 |
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