SG11202105995QA - Co-crystal of ketoprofen, compositions comprising the same, process of producing the same, and uses thereof - Google Patents

Co-crystal of ketoprofen, compositions comprising the same, process of producing the same, and uses thereof

Info

Publication number
SG11202105995QA
SG11202105995QA SG11202105995QA SG11202105995QA SG11202105995QA SG 11202105995Q A SG11202105995Q A SG 11202105995QA SG 11202105995Q A SG11202105995Q A SG 11202105995QA SG 11202105995Q A SG11202105995Q A SG 11202105995QA SG 11202105995Q A SG11202105995Q A SG 11202105995QA
Authority
SG
Singapore
Prior art keywords
same
ketoprofen
compositions
crystal
producing
Prior art date
Application number
SG11202105995QA
Inventor
Andrea Aramini
Gianluca Bianchini
Samuele Lillini
Original Assignee
Dompe Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Farm Spa filed Critical Dompe Farm Spa
Publication of SG11202105995QA publication Critical patent/SG11202105995QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/84Unsaturated compounds containing keto groups containing six membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/22Separation; Purification; Stabilisation; Use of additives
    • C07C231/24Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG11202105995QA 2018-12-21 2019-12-20 Co-crystal of ketoprofen, compositions comprising the same, process of producing the same, and uses thereof SG11202105995QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18215336.1A EP3670489A1 (en) 2018-12-21 2018-12-21 Co-crystal of ketoprofen, compositions comprising the same, process of producing the same, and uses thereof
PCT/EP2019/025464 WO2020126088A1 (en) 2018-12-21 2019-12-20 Co-crystal of ketoprofen, compositions comprising the same, process of producing the same, and uses thereof

Publications (1)

Publication Number Publication Date
SG11202105995QA true SG11202105995QA (en) 2021-07-29

Family

ID=65013486

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202105995QA SG11202105995QA (en) 2018-12-21 2019-12-20 Co-crystal of ketoprofen, compositions comprising the same, process of producing the same, and uses thereof

Country Status (9)

Country Link
US (1) US20220071936A1 (en)
EP (2) EP3670489A1 (en)
CN (1) CN113195445A (en)
BR (1) BR112021011368A2 (en)
CA (1) CA3122142A1 (en)
IL (1) IL283902A (en)
MA (1) MA54504A (en)
SG (1) SG11202105995QA (en)
WO (1) WO2020126088A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3907214A1 (en) * 2020-05-04 2021-11-10 Dompe' Farmaceutici S.P.A. Co-crystal of ketoprofen, lysine and gabapentin, pharmaceutical compositions and their medical use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
IT1104556B (en) * 1977-05-12 1985-10-21 Medea Res Srl Salt of lysine with meta-benzoyl-hydratropic acid - used as non-ulcerogenic antiinflammatory, analgesic and anti-agglutinant

Also Published As

Publication number Publication date
EP3670489A1 (en) 2020-06-24
BR112021011368A2 (en) 2022-03-03
MA54504A (en) 2022-03-30
US20220071936A1 (en) 2022-03-10
IL283902A (en) 2021-07-29
EP3898569A1 (en) 2021-10-27
CA3122142A1 (en) 2020-06-25
WO2020126088A1 (en) 2020-06-25
CN113195445A (en) 2021-07-30

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