SG11202105915UA - Methods for treating cancer in models harboring esr1 mutations - Google Patents

Methods for treating cancer in models harboring esr1 mutations

Info

Publication number
SG11202105915UA
SG11202105915UA SG11202105915UA SG11202105915UA SG11202105915UA SG 11202105915U A SG11202105915U A SG 11202105915UA SG 11202105915U A SG11202105915U A SG 11202105915UA SG 11202105915U A SG11202105915U A SG 11202105915UA SG 11202105915U A SG11202105915U A SG 11202105915UA
Authority
SG
Singapore
Prior art keywords
methods
treating cancer
esr1 mutations
models harboring
harboring esr1
Prior art date
Application number
SG11202105915UA
Inventor
Hitisha Patel
Teeru Bihani
Heike Arlt
Nianjun Tao
Original Assignee
Radius Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Radius Pharmaceuticals Inc filed Critical Radius Pharmaceuticals Inc
Publication of SG11202105915UA publication Critical patent/SG11202105915UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11202105915UA 2018-12-06 2019-12-06 Methods for treating cancer in models harboring esr1 mutations SG11202105915UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862776338P 2018-12-06 2018-12-06
PCT/US2019/064980 WO2020118202A1 (en) 2018-12-06 2019-12-06 Methods for treating cancer in models harboring esr1 mutations

Publications (1)

Publication Number Publication Date
SG11202105915UA true SG11202105915UA (en) 2021-07-29

Family

ID=69158304

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202105915UA SG11202105915UA (en) 2018-12-06 2019-12-06 Methods for treating cancer in models harboring esr1 mutations

Country Status (13)

Country Link
US (1) US20220016052A1 (en)
EP (1) EP3890835A1 (en)
KR (1) KR20210100135A (en)
AU (1) AU2019392908A1 (en)
BR (1) BR112021010141A2 (en)
CA (1) CA3121918A1 (en)
EA (1) EA202191256A1 (en)
IL (1) IL283655A (en)
JO (1) JOP20210138A1 (en)
MA (1) MA54393A (en)
MX (1) MX2021006412A (en)
SG (1) SG11202105915UA (en)
WO (1) WO2020118202A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7019422B2 (en) * 2015-04-29 2022-02-15 ラジウス ファーマシューティカルズ,インコーポレイテッド How to treat cancer

Also Published As

Publication number Publication date
WO2020118202A1 (en) 2020-06-11
CA3121918A1 (en) 2020-06-11
US20220016052A1 (en) 2022-01-20
BR112021010141A2 (en) 2021-08-24
EA202191256A1 (en) 2021-10-06
MX2021006412A (en) 2021-07-21
MA54393A (en) 2021-10-13
EP3890835A1 (en) 2021-10-13
JP2022511497A (en) 2022-01-31
KR20210100135A (en) 2021-08-13
IL283655A (en) 2021-07-29
AU2019392908A1 (en) 2021-06-10
JOP20210138A1 (en) 2023-01-30

Similar Documents

Publication Publication Date Title
IL272470A (en) Methods and materials for assessing and treating cancer
IL267247B (en) Compositions and methods for treating cancer
HK1251407A1 (en) Methods for treating cancer
IL264034A (en) Crispr/cas9-based compositions and methods for treating cancer
IL270720A (en) Combination therapies for treating cancer
ZA201706616B (en) Method for treating cancer
IL296080B1 (en) Method for treating cancer
IL266053A (en) Compositions and methods for treating ezh2-mediated cancer
IL257691A (en) Method for treating cancer
SG11202104356VA (en) Bt1718 for use in treating cancer
HK1254258A1 (en) Methods for treating cancer using apilimod
EP3344294A4 (en) Chimeric aav-anti-vegf for treating cancer in canines
SG11202002862RA (en) Combination therapies for treating cancer
EP3405203A4 (en) Methods for treating cancer
HK1255815A1 (en) Compositions and methods for treating peritoneal cancers
EP3440112A4 (en) Methods for treating cancer
EP3389634A4 (en) Methods for treating cancer
EP3177292A4 (en) Compounds and methods for treating cancer
IL255079A0 (en) Methods for treating lung cancer
SG11201708504XA (en) Methods for treating cancer
EP3271483A4 (en) Methods and materials for assessing and treating cancer
EP3408412A4 (en) Methods for assessing risk of developing colorectal cancer
HK1248135A1 (en) Combination method for treating cancer
IL255018A0 (en) Methods for treating cancer
SG10202013112YA (en) Zinc-gamma-pga compositions and methods for treating cancer