SG11202104845QA - Continuos flow synthesis of cannabidiol - Google Patents

Continuos flow synthesis of cannabidiol

Info

Publication number
SG11202104845QA
SG11202104845QA SG11202104845QA SG11202104845QA SG11202104845QA SG 11202104845Q A SG11202104845Q A SG 11202104845QA SG 11202104845Q A SG11202104845Q A SG 11202104845QA SG 11202104845Q A SG11202104845Q A SG 11202104845QA SG 11202104845Q A SG11202104845Q A SG 11202104845QA
Authority
SG
Singapore
Prior art keywords
cannabidiol
flow synthesis
continuos flow
continuos
synthesis
Prior art date
Application number
SG11202104845QA
Inventor
Alessandro Palmieri
Roberto Ballini
Pietro Allegrini
Daniele Ciceri
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of SG11202104845QA publication Critical patent/SG11202104845QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/11Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
    • C07C37/16Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms by condensation involving hydroxy groups of phenols or alcohols or the ether or mineral ester group derived therefrom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/11Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
    • C07C37/14Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms by addition reactions, i.e. reactions involving at least one carbon-to-carbon unsaturated bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/68Purification; separation; Use of additives, e.g. for stabilisation
    • C07C37/70Purification; separation; Use of additives, e.g. for stabilisation by physical treatment
    • C07C37/72Purification; separation; Use of additives, e.g. for stabilisation by physical treatment by liquid-liquid treatment
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/68Purification; separation; Use of additives, e.g. for stabilisation
    • C07C37/70Purification; separation; Use of additives, e.g. for stabilisation by physical treatment
    • C07C37/82Purification; separation; Use of additives, e.g. for stabilisation by physical treatment by solid-liquid treatment; by chemisorption
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/23Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SG11202104845QA 2018-11-14 2019-11-11 Continuos flow synthesis of cannabidiol SG11202104845QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18206248.9A EP3653596A1 (en) 2018-11-14 2018-11-14 Continuous flow synthesis of cannabidiol
PCT/EP2019/080780 WO2020099283A1 (en) 2018-11-14 2019-11-11 Continuos flow synthesis of cannabidiol

Publications (1)

Publication Number Publication Date
SG11202104845QA true SG11202104845QA (en) 2021-06-29

Family

ID=64316398

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104845QA SG11202104845QA (en) 2018-11-14 2019-11-11 Continuos flow synthesis of cannabidiol

Country Status (12)

Country Link
US (1) US20220009865A1 (en)
EP (2) EP3653596A1 (en)
JP (1) JP7444876B2 (en)
KR (1) KR20210091773A (en)
CN (1) CN113015714B (en)
AU (1) AU2019379268A1 (en)
BR (1) BR112021009109B1 (en)
CA (1) CA3119712A1 (en)
IL (1) IL283059A (en)
MX (1) MX2021005695A (en)
SG (1) SG11202104845QA (en)
WO (1) WO2020099283A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10981850B2 (en) 2019-04-15 2021-04-20 Trustees Of Boston University One-step flow-mediated synthesis of cannabidiol (CBD) and derivatives
CN111943813B (en) * 2019-05-17 2023-04-14 上海特化医药科技有限公司 Preparation method of cannabidiol compound
GB202016536D0 (en) 2020-10-19 2020-12-02 Aesica Pharmaceuticals Ltd Process
WO2023046730A1 (en) 2021-09-22 2023-03-30 Bionorica Se Cosmetic compositions containing cannabidiol and zingiber extract

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2894040A (en) * 1953-09-28 1959-07-07 Glidden Co Isomerization of terpenic alcohols
TWI369203B (en) 2004-11-22 2012-08-01 Euro Celtique Sa Methods for purifying trans-(-)-△9-tetrahydrocannabinol and trans-(+)-△9-tetrahydrocannabinol
US20080108122A1 (en) * 2006-09-01 2008-05-08 State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon Microchemical nanofactories
EP2842933B1 (en) * 2013-09-03 2015-07-29 Symrise AG Mixtures of cannabinoid compounds, their preparation and use
US20170008869A1 (en) * 2015-07-10 2017-01-12 Noramco, Inc. Process for the production of cannabidiol and delta-9-tetrahydrocannabinol

Also Published As

Publication number Publication date
MX2021005695A (en) 2021-07-07
US20220009865A1 (en) 2022-01-13
CA3119712A1 (en) 2020-05-22
EP3653596A1 (en) 2020-05-20
KR20210091773A (en) 2021-07-22
CN113015714A (en) 2021-06-22
JP2022513011A (en) 2022-02-07
JP7444876B2 (en) 2024-03-06
IL283059A (en) 2021-06-30
AU2019379268A1 (en) 2021-06-24
BR112021009109B1 (en) 2024-02-20
EP3880637A1 (en) 2021-09-22
WO2020099283A1 (en) 2020-05-22
BR112021009109A2 (en) 2021-08-10
CN113015714B (en) 2023-08-25

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