SG11202104121QA - Methods for synthesis of radionuclide complex - Google Patents
Methods for synthesis of radionuclide complexInfo
- Publication number
- SG11202104121QA SG11202104121QA SG11202104121QA SG11202104121QA SG11202104121QA SG 11202104121Q A SG11202104121Q A SG 11202104121QA SG 11202104121Q A SG11202104121Q A SG 11202104121QA SG 11202104121Q A SG11202104121Q A SG 11202104121QA SG 11202104121Q A SG11202104121Q A SG 11202104121QA
- Authority
- SG
- Singapore
- Prior art keywords
- synthesis
- methods
- radionuclide complex
- radionuclide
- complex
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/008—Peptides; Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/121—Solutions, i.e. homogeneous liquid formulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/13—Labelling of peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dispersion Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2018/079909 WO2020088767A1 (en) | 2018-10-31 | 2018-10-31 | Methods for synthesis of radionuclide complex |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202104121QA true SG11202104121QA (en) | 2021-05-28 |
Family
ID=64083105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202104121QA SG11202104121QA (en) | 2018-10-31 | 2018-10-31 | Methods for synthesis of radionuclide complex |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20200131224A1 (en) |
| EP (1) | EP3873874A1 (en) |
| JP (2) | JP2022516814A (en) |
| KR (1) | KR20210086637A (en) |
| CN (1) | CN112969675A (en) |
| BR (1) | BR112021007851A2 (en) |
| CA (1) | CA3159337A1 (en) |
| IL (1) | IL282701A (en) |
| SG (1) | SG11202104121QA (en) |
| WO (2) | WO2020088767A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10596276B2 (en) | 2018-07-25 | 2020-03-24 | Advanced Accelerator Applications (Italy) S.R.L. | Stable, concentrated radionuclide complex solutions |
| CA3190855A1 (en) | 2020-08-27 | 2022-03-03 | Joe Mccann | Radiopharmaceutical and methods |
| CA3191472A1 (en) * | 2020-09-03 | 2022-03-10 | Curium Us Llc | Radiolabeling and formulation for scale up of 64cu-dotatate |
| CN114685608B (en) * | 2020-12-29 | 2023-10-20 | 北京大学深圳研究生院 | Cyclic peptide compound containing trithiophene bond or derivative thereof, synthesis method and application thereof |
| US11541134B1 (en) | 2021-08-02 | 2023-01-03 | Rayzebio, Inc. | Stabilized compositions of radionuclides and uses thereof |
| IT202100024377A1 (en) * | 2021-09-22 | 2023-03-22 | Scogif S R L | AUTOMATIC EQUIPMENT FOR THE SYNTHESIS OF PEPTIDE-BASED RADIO-PHARMACEUTICALS FOR DIAGNOSTIC AND/OR THERAPEUTIC USE |
| WO2023148680A1 (en) * | 2022-02-04 | 2023-08-10 | Advanced Accelerator Applications | Methods for large scale synthesis of radionuclide complexes |
| US20230248853A1 (en) * | 2022-02-04 | 2023-08-10 | Westinghouse Electric Company Llc | Method and device for direct production of radio-isotope based cancer treatment pharmaceuticals |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101855509B1 (en) * | 2015-11-12 | 2018-05-09 | 한국원자력연구원 | Vial kit for manufacturing radiopharmaceutical and manufacturing method for using the same |
-
2018
- 2018-10-31 JP JP2021547881A patent/JP2022516814A/en active Pending
- 2018-10-31 SG SG11202104121QA patent/SG11202104121QA/en unknown
- 2018-10-31 CN CN201880099176.3A patent/CN112969675A/en active Pending
- 2018-10-31 KR KR1020217013140A patent/KR20210086637A/en not_active Application Discontinuation
- 2018-10-31 WO PCT/EP2018/079909 patent/WO2020088767A1/en active Application Filing
- 2018-10-31 CA CA3159337A patent/CA3159337A1/en active Pending
-
2019
- 2019-04-24 US US16/393,103 patent/US20200131224A1/en not_active Abandoned
- 2019-10-31 WO PCT/EP2019/079799 patent/WO2020089379A1/en unknown
- 2019-10-31 BR BR112021007851-7A patent/BR112021007851A2/en unknown
- 2019-10-31 US US17/290,337 patent/US20210316019A1/en active Pending
- 2019-10-31 EP EP19794576.9A patent/EP3873874A1/en active Pending
-
2021
- 2021-04-27 IL IL282701A patent/IL282701A/en unknown
- 2021-05-27 US US17/331,927 patent/US20220041649A1/en active Pending
-
2023
- 2023-10-19 JP JP2023180277A patent/JP2023178388A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20210086637A (en) | 2021-07-08 |
| AU2018447938A1 (en) | 2021-05-13 |
| WO2020089379A1 (en) | 2020-05-07 |
| US20200131224A1 (en) | 2020-04-30 |
| EP3873874A1 (en) | 2021-09-08 |
| WO2020088767A1 (en) | 2020-05-07 |
| IL282701A (en) | 2021-06-30 |
| CA3159337A1 (en) | 2020-05-07 |
| BR112021007851A2 (en) | 2021-08-03 |
| JP2022516814A (en) | 2022-03-02 |
| CN112969675A (en) | 2021-06-15 |
| US20210316019A1 (en) | 2021-10-14 |
| US20220041649A1 (en) | 2022-02-10 |
| JP2023178388A (en) | 2023-12-14 |
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