SG11202102744PA - Method for identifying a chemical compound or agent inducing ubiquitination of a protein of interest - Google Patents
Method for identifying a chemical compound or agent inducing ubiquitination of a protein of interestInfo
- Publication number
- SG11202102744PA SG11202102744PA SG11202102744PA SG11202102744PA SG11202102744PA SG 11202102744P A SG11202102744P A SG 11202102744PA SG 11202102744P A SG11202102744P A SG 11202102744PA SG 11202102744P A SG11202102744P A SG 11202102744PA SG 11202102744P A SG11202102744P A SG 11202102744PA
- Authority
- SG
- Singapore
- Prior art keywords
- interest
- protein
- identifying
- chemical compound
- agent inducing
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/36—Post-translational modifications [PTMs] in chemical analysis of biological material addition of addition of other proteins or peptides, e.g. SUMOylation, ubiquitination
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18200834 | 2018-10-16 | ||
| PCT/EP2019/078125 WO2020079103A1 (en) | 2018-10-16 | 2019-10-16 | Method for identifying a chemical compound or agent inducing ubiquitination of a protein of interest |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202102744PA true SG11202102744PA (en) | 2021-04-29 |
Family
ID=63878464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202102744PA SG11202102744PA (en) | 2018-10-16 | 2019-10-16 | Method for identifying a chemical compound or agent inducing ubiquitination of a protein of interest |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20210293788A1 (en) |
| EP (1) | EP3867640B9 (en) |
| SG (1) | SG11202102744PA (en) |
| WO (1) | WO2020079103A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10988759B2 (en) | 2016-01-15 | 2021-04-27 | University Of Washington | High throughput protein-protein interaction screening in yeast liquid culture |
| AU2019362863A1 (en) * | 2018-10-17 | 2021-06-03 | University Of Washington | Methods for screening ubiquitin ligase agonists |
| CN115552003A (en) * | 2020-05-11 | 2022-12-30 | A-阿尔法生物股份有限公司 | High throughput screening method for identifying small molecule targets |
| EP4158015A1 (en) | 2020-06-01 | 2023-04-05 | A-Alpha Bio, Inc. | Methods for characterizing and engineering protein-protein interactions |
| WO2022152821A1 (en) | 2021-01-13 | 2022-07-21 | Monte Rosa Therapeutics Ag | Isoindolinone compounds |
| CN113403382B (en) * | 2021-06-17 | 2022-09-20 | 西安市红会医院 | Application of UBE2F in diagnosis and treatment of femoral head necrosis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4452901A (en) | 1980-03-20 | 1984-06-05 | Ciba-Geigy Corporation | Electrophoretically transferring electropherograms to nitrocellulose sheets for immuno-assays |
| EP3000479A1 (en) * | 2014-09-23 | 2016-03-30 | Klinikum rechts der Isar der Technischen Universität München | Method for assessing the efficacy of IMiDs and composition or combination for use in treating IMiD sensitive diseases |
-
2019
- 2019-10-16 WO PCT/EP2019/078125 patent/WO2020079103A1/en unknown
- 2019-10-16 SG SG11202102744PA patent/SG11202102744PA/en unknown
- 2019-10-16 EP EP19786586.8A patent/EP3867640B9/en active Active
- 2019-10-16 US US17/285,698 patent/US20210293788A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20210293788A1 (en) | 2021-09-23 |
| WO2020079103A1 (en) | 2020-04-23 |
| EP3867640B1 (en) | 2023-06-07 |
| EP3867640B9 (en) | 2023-10-04 |
| EP3867640A1 (en) | 2021-08-25 |
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