SG11202102029TA - Methods for generating spatially barcoded arrays - Google Patents
Methods for generating spatially barcoded arraysInfo
- Publication number
- SG11202102029TA SG11202102029TA SG11202102029TA SG11202102029TA SG11202102029TA SG 11202102029T A SG11202102029T A SG 11202102029TA SG 11202102029T A SG11202102029T A SG 11202102029TA SG 11202102029T A SG11202102029T A SG 11202102029TA SG 11202102029T A SG11202102029T A SG 11202102029TA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- generating spatially
- spatially barcoded
- barcoded arrays
- arrays
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Lubricants (AREA)
Applications Claiming Priority (43)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862723960P | 2018-08-28 | 2018-08-28 | |
| US201862723972P | 2018-08-28 | 2018-08-28 | |
| US201862723964P | 2018-08-28 | 2018-08-28 | |
| US201862723970P | 2018-08-28 | 2018-08-28 | |
| US201862723950P | 2018-08-28 | 2018-08-28 | |
| US201862723957P | 2018-08-28 | 2018-08-28 | |
| US201862724483P | 2018-08-29 | 2018-08-29 | |
| US201862724561P | 2018-08-29 | 2018-08-29 | |
| US201862724487P | 2018-08-29 | 2018-08-29 | |
| US201862724489P | 2018-08-29 | 2018-08-29 | |
| US201862779342P | 2018-12-13 | 2018-12-13 | |
| US201962788867P | 2019-01-06 | 2019-01-06 | |
| US201962788871P | 2019-01-06 | 2019-01-06 | |
| US201962788897P | 2019-01-06 | 2019-01-06 | |
| US201962788905P | 2019-01-06 | 2019-01-06 | |
| US201962788885P | 2019-01-06 | 2019-01-06 | |
| US201962812219P | 2019-02-28 | 2019-02-28 | |
| US201962819468P | 2019-03-15 | 2019-03-15 | |
| US201962819456P | 2019-03-15 | 2019-03-15 | |
| US201962819449P | 2019-03-15 | 2019-03-15 | |
| US201962819486P | 2019-03-15 | 2019-03-15 | |
| US201962819478P | 2019-03-15 | 2019-03-15 | |
| US201962819496P | 2019-03-15 | 2019-03-15 | |
| US201962819448P | 2019-03-15 | 2019-03-15 | |
| US201962819458P | 2019-03-15 | 2019-03-15 | |
| US201962819467P | 2019-03-15 | 2019-03-15 | |
| US201962822618P | 2019-03-22 | 2019-03-22 | |
| US201962822632P | 2019-03-22 | 2019-03-22 | |
| US201962822627P | 2019-03-22 | 2019-03-22 | |
| US201962822575P | 2019-03-22 | 2019-03-22 | |
| US201962822605P | 2019-03-22 | 2019-03-22 | |
| US201962822554P | 2019-03-22 | 2019-03-22 | |
| US201962822649P | 2019-03-22 | 2019-03-22 | |
| US201962822565P | 2019-03-22 | 2019-03-22 | |
| US201962822592P | 2019-03-22 | 2019-03-22 | |
| US201962839346P | 2019-04-26 | 2019-04-26 | |
| US201962839526P | 2019-04-26 | 2019-04-26 | |
| US201962839320P | 2019-04-26 | 2019-04-26 | |
| US201962839223P | 2019-04-26 | 2019-04-26 | |
| US201962842463P | 2019-05-02 | 2019-05-02 | |
| US201962858331P | 2019-06-07 | 2019-06-07 | |
| US201962860993P | 2019-06-13 | 2019-06-13 | |
| PCT/US2019/048430 WO2020047007A2 (en) | 2018-08-28 | 2019-08-27 | Methods for generating spatially barcoded arrays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202102029TA true SG11202102029TA (en) | 2021-03-30 |
Family
ID=69643282
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202102019UA SG11202102019UA (en) | 2018-08-28 | 2019-08-27 | Method for transposase-mediated spatial tagging and analyzing genomic dna in a biological sample |
| SG11202101944RA SG11202101944RA (en) | 2018-08-28 | 2019-08-27 | Increasing spatial array resolution |
| SG11202102029TA SG11202102029TA (en) | 2018-08-28 | 2019-08-27 | Methods for generating spatially barcoded arrays |
| SG11202102003TA SG11202102003TA (en) | 2018-08-28 | 2019-08-27 | Methods of generating an array |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202102019UA SG11202102019UA (en) | 2018-08-28 | 2019-08-27 | Method for transposase-mediated spatial tagging and analyzing genomic dna in a biological sample |
| SG11202101944RA SG11202101944RA (en) | 2018-08-28 | 2019-08-27 | Increasing spatial array resolution |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202102003TA SG11202102003TA (en) | 2018-08-28 | 2019-08-27 | Methods of generating an array |
Country Status (5)
| Country | Link |
|---|---|
| US (5) | US20210332425A1 (en) |
| EP (4) | EP3844305A2 (en) |
| CN (3) | CN113767175A (en) |
| SG (4) | SG11202102019UA (en) |
| WO (4) | WO2020047002A1 (en) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| AU2011237729B2 (en) | 2010-04-05 | 2014-04-03 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| EP3901280A1 (en) | 2012-10-17 | 2021-10-27 | Spatial Transcriptomics AB | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
| EP4234716A3 (en) | 2013-06-25 | 2023-12-06 | Prognosys Biosciences, Inc. | Methods for determining spatial patterns of biological targets in a sample |
| CA2982146A1 (en) | 2015-04-10 | 2016-10-13 | Spatial Transcriptomics Ab | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| US11773441B2 (en) | 2018-05-03 | 2023-10-03 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| US20220049294A1 (en) | 2018-12-10 | 2022-02-17 | 10X Genomics, Inc. | Imaging system hardware |
| US20240026445A1 (en) * | 2019-01-06 | 2024-01-25 | 10X Genomics, Inc. | Methods for determining a location of a biological analyte in a biological sample |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| JP2022523362A (en) * | 2019-02-21 | 2022-04-22 | ストラトス ゲノミクス インコーポレイテッド | Methods, compositions, and devices for solid-state synthesis of expandable polymers for use in single-molecule sequencing. |
| EP3976820A1 (en) | 2019-05-30 | 2022-04-06 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| WO2021091611A1 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Spatially-tagged analyte capture agents for analyte multiplexing |
| WO2021092433A2 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
| WO2021097255A1 (en) * | 2019-11-13 | 2021-05-20 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| EP4062372B1 (en) * | 2019-11-22 | 2024-05-08 | 10X Genomics, Inc. | Systems and methods for spatial analysis of analytes using fiducial alignment |
| WO2021119320A2 (en) | 2019-12-11 | 2021-06-17 | 10X Genomics, Inc. | Reverse transcriptase variants |
| ES2946357T3 (en) | 2019-12-23 | 2023-07-17 | 10X Genomics Inc | Methods for spatial analysis using RNA template ligation |
| CA3167725A1 (en) | 2020-01-13 | 2021-07-22 | Fluent Biosciences Inc. | Single cell sequencing |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US11821035B1 (en) | 2020-01-29 | 2023-11-21 | 10X Genomics, Inc. | Compositions and methods of making gene expression libraries |
| US12076701B2 (en) | 2020-01-31 | 2024-09-03 | 10X Genomics, Inc. | Capturing oligonucleotides in spatial transcriptomics |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| US11835462B2 (en) | 2020-02-11 | 2023-12-05 | 10X Genomics, Inc. | Methods and compositions for partitioning a biological sample |
| WO2021168278A1 (en) * | 2020-02-20 | 2021-08-26 | 10X Genomics, Inc. | METHODS TO COMBINE FIRST AND SECOND STRAND cDNA SYNTHESIS FOR SPATIAL ANALYSIS |
| CN116157533A (en) * | 2020-02-21 | 2023-05-23 | 10X基因组学有限公司 | Capturing genetic targets using hybridization methods |
| US20210262018A1 (en) | 2020-02-21 | 2021-08-26 | 10X Genomics, Inc. | Methods and compositions for integrated in situ spatial assay |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| US11926863B1 (en) | 2020-02-27 | 2024-03-12 | 10X Genomics, Inc. | Solid state single cell method for analyzing fixed biological cells |
| US11768175B1 (en) | 2020-03-04 | 2023-09-26 | 10X Genomics, Inc. | Electrophoretic methods for spatial analysis |
| WO2021188500A1 (en) | 2020-03-16 | 2021-09-23 | Fluent Biosciences Inc. | Multi-omic analysis in monodisperse droplets |
| WO2021212042A1 (en) | 2020-04-16 | 2021-10-21 | 10X Genomics, Inc. | Compositions and methods for use with fixed samples |
| CN115916999A (en) | 2020-04-22 | 2023-04-04 | 10X基因组学有限公司 | Methods for spatial analysis using targeted RNA depletion |
| US20230265491A1 (en) * | 2020-05-04 | 2023-08-24 | 10X Genomics, Inc. | Spatial transcriptomic transfer modes |
| US11851700B1 (en) | 2020-05-13 | 2023-12-26 | 10X Genomics, Inc. | Methods, kits, and compositions for processing extracellular molecules |
| WO2021237087A1 (en) | 2020-05-22 | 2021-11-25 | 10X Genomics, Inc. | Spatial analysis to detect sequence variants |
| EP4414459A3 (en) | 2020-05-22 | 2024-09-18 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
| WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
| AU2021283174A1 (en) | 2020-06-02 | 2023-01-05 | 10X Genomics, Inc. | Nucleic acid library methods |
| AU2021283184A1 (en) | 2020-06-02 | 2023-01-05 | 10X Genomics, Inc. | Spatial transcriptomics for antigen-receptors |
| CA3181004A1 (en) * | 2020-06-03 | 2021-12-09 | Weiyang SHI | Method for analyzing target nucleic acid from cell |
| US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
| EP4162074B1 (en) | 2020-06-08 | 2024-04-24 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| EP4165207B1 (en) | 2020-06-10 | 2024-09-25 | 10X Genomics, Inc. | Methods for determining a location of an analyte in a biological sample |
| EP4172362B1 (en) | 2020-06-25 | 2024-09-18 | 10X Genomics, Inc. | Spatial analysis of dna methylation |
| US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| WO2022035729A1 (en) * | 2020-08-10 | 2022-02-17 | Dimensiongen | Devices and methods for multi-dimensional genome analysis |
| US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
| US20240033743A1 (en) * | 2020-09-18 | 2024-02-01 | 10X Genomics, Inc. | Sample handling apparatus and fluid delivery methods |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| CN114085897A (en) * | 2020-09-29 | 2022-02-25 | 生物岛实验室 | Space omics sequencing method |
| WO2022067565A1 (en) * | 2020-09-29 | 2022-04-07 | 生物岛实验室 | Spatial omics sequencing method, single cell epitranscriptomic sequencing method, and localization labeling method |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| WO2022132645A1 (en) * | 2020-12-14 | 2022-06-23 | Chan Zuckerberg Biohub, Inc. | Spatial genomics with single cell resolution |
| EP4121555A1 (en) | 2020-12-21 | 2023-01-25 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| WO2022147296A1 (en) | 2020-12-30 | 2022-07-07 | 10X Genomics, Inc. | Cleavage of capture probes for spatial analysis |
| US20220228201A1 (en) * | 2020-12-30 | 2022-07-21 | 10X Genomics, Inc. | Molecular arrays and methods for generating and using the arrays |
| EP4271804A1 (en) * | 2020-12-30 | 2023-11-08 | Dovetail Genomics, LLC | Methods and compositions for sequencing library preparation |
| WO2022147139A1 (en) * | 2020-12-30 | 2022-07-07 | 10X Genomics, Inc. | Methods and compositions for light-controlled surface patterning using a polymer |
| CN116917499A (en) * | 2021-01-12 | 2023-10-20 | 巴黎科学与文学联大 | Method for spatially mapping and sequencing cells or organelles |
| EP4301870A1 (en) | 2021-03-18 | 2024-01-10 | 10X Genomics, Inc. | Multiplex capture of gene and protein expression from a biological sample |
| EP4305196A1 (en) * | 2021-04-14 | 2024-01-17 | 10X Genomics, Inc. | Methods of measuring mislocalization of an analyte |
| US20240218432A1 (en) * | 2021-04-20 | 2024-07-04 | 10X Genomics, Inc. | Methods for assessing sample quality prior to spatial analysis using templated ligation |
| WO2022226372A1 (en) * | 2021-04-23 | 2022-10-27 | Ultima Genomics, Inc. | Systems and methods for spatial reference sequencing |
| WO2022232631A1 (en) * | 2021-04-30 | 2022-11-03 | Quantum-Si Incorporated | Universal adaptor for sequencing |
| WO2022232571A1 (en) | 2021-04-30 | 2022-11-03 | 10X Genomics, Inc. | Fusion rt variants for improved performance |
| CN117642633A (en) * | 2021-05-26 | 2024-03-01 | 德克萨斯大学系统董事会 | Method and system for single cell protein analysis |
| EP4348245A1 (en) * | 2021-05-28 | 2024-04-10 | Fluent Biosciences Inc. | Spatial transcriptomics in pips |
| WO2022256503A1 (en) | 2021-06-03 | 2022-12-08 | 10X Genomics, Inc. | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
| WO2022265965A1 (en) | 2021-06-14 | 2022-12-22 | 10X Genomics, Inc. | Reverse transcriptase variants for improved performance |
| WO2023034489A1 (en) | 2021-09-01 | 2023-03-09 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
| US20230139059A1 (en) * | 2021-10-04 | 2023-05-04 | AtlasXomics Inc. | System and methods for high throughput screening of tissue preparation conditions |
| WO2023076345A1 (en) * | 2021-10-26 | 2023-05-04 | 10X Genomics, Inc. | Methods for spatial analysis using targeted rna capture |
| WO2023114473A2 (en) | 2021-12-16 | 2023-06-22 | 10X Genomics, Inc. | Recombinant reverse transcriptase variants for improved performance |
| WO2023116938A1 (en) * | 2021-12-24 | 2023-06-29 | 映泰科技有限公司 | Biochip for spatial transcriptomic analysis, and preparation method and application thereof |
| CN116694730A (en) * | 2022-02-28 | 2023-09-05 | 南方科技大学 | Construction method of single cell open chromatin and transcriptome co-sequencing library |
| CN114574569B (en) * | 2022-03-28 | 2023-05-16 | 浙江大学 | Genome sequencing kit and sequencing method based on terminal transferase |
| US20230323427A1 (en) | 2022-04-06 | 2023-10-12 | 10X Genomics, Inc. | Methods and compositions for multiplex cell analysis |
| WO2023215612A1 (en) | 2022-05-06 | 2023-11-09 | 10X Genomics, Inc. | Analysis of antigen and antigen receptor interactions |
| WO2023225519A1 (en) | 2022-05-17 | 2023-11-23 | 10X Genomics, Inc. | Modified transposons, compositions and uses thereof |
| WO2023250077A1 (en) * | 2022-06-22 | 2023-12-28 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| WO2024006799A1 (en) * | 2022-06-29 | 2024-01-04 | 10X Genomics, Inc. | Covalent attachment of splint oligonucleotides for molecular array generation using ligation |
| US20240002932A1 (en) * | 2022-06-29 | 2024-01-04 | 10X Genomics, Inc. | Click chemistry-based dna photo-ligation for manufacturing of high-resolution dna arrays |
| WO2024112703A1 (en) * | 2022-11-21 | 2024-05-30 | Illumina, Inc. | Reversibly cross-linked hydrogels, and methods of using the same for cluster amplification |
| WO2024112948A1 (en) | 2022-11-23 | 2024-05-30 | Alida Biosciences, Inc. | Chromatin profiling compositions and methods |
| WO2024124044A1 (en) | 2022-12-07 | 2024-06-13 | The Brigham And Women’S Hospital, Inc. | Compositions and methods targeting sat1 for enhancing anti¬ tumor immunity during tumor progression |
| WO2024141901A1 (en) * | 2022-12-28 | 2024-07-04 | Moleculent Ab | Heat-based transfer of reaction products made in situ to a planar support |
| CN117385477B (en) * | 2023-03-10 | 2024-09-20 | 深圳赛陆医疗科技有限公司 | Chip for space transcriptome sequencing, preparation method thereof and space transcriptome sequencing method |
Family Cites Families (135)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US4968601A (en) * | 1988-02-09 | 1990-11-06 | The United States Of America As Represented By The Dept. Of Health & Human Services | Method for diagnosing latent viral infection |
| US5472881A (en) | 1992-11-12 | 1995-12-05 | University Of Utah Research Foundation | Thiol labeling of DNA for attachment to gold surfaces |
| DE69434520T3 (en) | 1993-07-30 | 2009-10-15 | Affymax, Inc., Palo Alto | BIOTINYLATION OF PROTEINS |
| US5610287A (en) | 1993-12-06 | 1997-03-11 | Molecular Tool, Inc. | Method for immobilizing nucleic acid molecules |
| US5512462A (en) | 1994-02-25 | 1996-04-30 | Hoffmann-La Roche Inc. | Methods and reagents for the polymerase chain reaction amplification of long DNA sequences |
| US5677170A (en) | 1994-03-02 | 1997-10-14 | The Johns Hopkins University | In vitro transposition of artificial transposons |
| US5552278A (en) | 1994-04-04 | 1996-09-03 | Spectragen, Inc. | DNA sequencing by stepwise ligation and cleavage |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5641658A (en) | 1994-08-03 | 1997-06-24 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid with two primers bound to a single solid support |
| US5846719A (en) | 1994-10-13 | 1998-12-08 | Lynx Therapeutics, Inc. | Oligonucleotide tags for sorting and identification |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| US5925545A (en) | 1996-09-09 | 1999-07-20 | Wisconsin Alumni Research Foundation | System for in vitro transposition |
| US5965443A (en) | 1996-09-09 | 1999-10-12 | Wisconsin Alumni Research Foundation | System for in vitro transposition |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| JP2001509828A (en) | 1997-01-08 | 2001-07-24 | プロリゴ・エルエルシー | Bioconjugation of macromolecules |
| US5837860A (en) | 1997-03-05 | 1998-11-17 | Molecular Tool, Inc. | Covalent attachment of nucleic acid molecules onto solid-phases via disulfide bonds |
| US6327410B1 (en) | 1997-03-14 | 2001-12-04 | The Trustees Of Tufts College | Target analyte sensors utilizing Microspheres |
| US6023540A (en) | 1997-03-14 | 2000-02-08 | Trustees Of Tufts College | Fiber optic sensor with encoded microspheres |
| EP3034626A1 (en) | 1997-04-01 | 2016-06-22 | Illumina Cambridge Limited | Method of nucleic acid sequencing |
| WO1998044152A1 (en) | 1997-04-01 | 1998-10-08 | Glaxo Group Limited | Method of nucleic acid sequencing |
| US6969488B2 (en) | 1998-05-22 | 2005-11-29 | Solexa, Inc. | System and apparatus for sequential processing of analytes |
| US5919626A (en) | 1997-06-06 | 1999-07-06 | Orchid Bio Computer, Inc. | Attachment of unmodified nucleic acids to silanized solid phase surfaces |
| US7427678B2 (en) | 1998-01-08 | 2008-09-23 | Sigma-Aldrich Co. | Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method |
| US6387632B2 (en) * | 1998-06-11 | 2002-05-14 | Hitachi, Ltd. | Polynucleotide separation method and apparatus therefor |
| EP2360271A1 (en) | 1998-06-24 | 2011-08-24 | Illumina, Inc. | Decoding of array sensors with microspheres |
| US6159736A (en) | 1998-09-23 | 2000-12-12 | Wisconsin Alumni Research Foundation | Method for making insertional mutations using a Tn5 synaptic complex |
| AR021833A1 (en) | 1998-09-30 | 2002-08-07 | Applied Research Systems | METHODS OF AMPLIFICATION AND SEQUENCING OF NUCLEIC ACID |
| US6391937B1 (en) | 1998-11-25 | 2002-05-21 | Motorola, Inc. | Polyacrylamide hydrogels and hydrogel arrays made from polyacrylamide reactive prepolymers |
| US20060275782A1 (en) * | 1999-04-20 | 2006-12-07 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| WO2000063437A2 (en) | 1999-04-20 | 2000-10-26 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| US6355431B1 (en) | 1999-04-20 | 2002-03-12 | Illumina, Inc. | Detection of nucleic acid amplification reactions using bead arrays |
| CA2380850A1 (en) | 1999-08-02 | 2001-02-08 | Wisconsin Alumni Research Foundation | Mutant tn5 transposase enzymes and method for their use |
| US7244559B2 (en) | 1999-09-16 | 2007-07-17 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US6274320B1 (en) | 1999-09-16 | 2001-08-14 | Curagen Corporation | Method of sequencing a nucleic acid |
| US6770441B2 (en) | 2000-02-10 | 2004-08-03 | Illumina, Inc. | Array compositions and methods of making same |
| US7001792B2 (en) | 2000-04-24 | 2006-02-21 | Eagle Research & Development, Llc | Ultra-fast nucleic acid sequencing device and a method for making and using the same |
| GB0018120D0 (en) | 2000-07-24 | 2000-09-13 | Fermentas Ab | Nuclease |
| AR031640A1 (en) | 2000-12-08 | 2003-09-24 | Applied Research Systems | ISOTHERMAL AMPLIFICATION OF NUCLEIC ACIDS IN A SOLID SUPPORT |
| US7297778B2 (en) * | 2001-07-25 | 2007-11-20 | Affymetrix, Inc. | Complexity management of genomic DNA |
| US20040019005A1 (en) * | 2001-10-01 | 2004-01-29 | Jeffrey Van Ness | Methods for parallel measurement of genetic variations |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| AU2003232881A1 (en) | 2002-01-16 | 2003-09-09 | Mayo Foundation For Medical Education And Research | Method and apparatus for image-guided therapy |
| US20040002090A1 (en) | 2002-03-05 | 2004-01-01 | Pascal Mayer | Methods for detecting genome-wide sequence variations associated with a phenotype |
| DK2226316T3 (en) | 2002-05-30 | 2016-04-11 | Scripps Research Inst | Copper catalyzed ligation of azides and acetylenes |
| SI3363809T1 (en) | 2002-08-23 | 2020-08-31 | Illumina Cambridge Limited | Modified nucleotides for polynucleotide sequencing |
| KR20040062847A (en) * | 2003-01-03 | 2004-07-09 | 삼성전자주식회사 | Method for replicating nucleic acid array |
| GB0302058D0 (en) * | 2003-01-29 | 2003-02-26 | Univ Cranfield | Replication of nucleic acid arrays |
| WO2004093645A2 (en) | 2003-04-17 | 2004-11-04 | Wisconsin Alumni Research Foundation | Tn5 transposase mutants and the use thereof |
| US20050031176A1 (en) | 2003-08-08 | 2005-02-10 | Hertel Sarah R. | Method and apparatus of multi-modality image fusion |
| GB0321306D0 (en) | 2003-09-11 | 2003-10-15 | Solexa Ltd | Modified polymerases for improved incorporation of nucleotide analogues |
| US7259258B2 (en) | 2003-12-17 | 2007-08-21 | Illumina, Inc. | Methods of attaching biological compounds to solid supports using triazine |
| EP2789383B1 (en) | 2004-01-07 | 2023-05-03 | Illumina Cambridge Limited | Molecular arrays |
| US7608434B2 (en) | 2004-08-04 | 2009-10-27 | Wisconsin Alumni Research Foundation | Mutated Tn5 transposase proteins and the use thereof |
| EP1828412B2 (en) | 2004-12-13 | 2019-01-09 | Illumina Cambridge Limited | Improved method of nucleotide detection |
| GB0427236D0 (en) | 2004-12-13 | 2005-01-12 | Solexa Ltd | Improved method of nucleotide detection |
| NZ563193A (en) * | 2005-05-09 | 2010-05-28 | Ono Pharmaceutical Co | Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics |
| JP4990886B2 (en) | 2005-05-10 | 2012-08-01 | ソレックサ リミテッド | Improved polymerase |
| WO2007001986A2 (en) | 2005-06-20 | 2007-01-04 | Yuling Luo | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
| GB0514936D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Preparation of templates for nucleic acid sequencing |
| GB0522310D0 (en) | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
| EP2021503A1 (en) | 2006-03-17 | 2009-02-11 | Solexa Ltd. | Isothermal methods for creating clonal single molecule arrays |
| WO2007111937A1 (en) * | 2006-03-23 | 2007-10-04 | Applera Corporation | Directed enrichment of genomic dna for high-throughput sequencing |
| WO2008021123A1 (en) | 2006-08-07 | 2008-02-21 | President And Fellows Of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
| WO2008022332A2 (en) * | 2006-08-18 | 2008-02-21 | Board Of Regents, The University Of Texas System | System, method and kit for replicating a dna array |
| US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US8349167B2 (en) | 2006-12-14 | 2013-01-08 | Life Technologies Corporation | Methods and apparatus for detecting molecular interactions using FET arrays |
| EP2677308B1 (en) | 2006-12-14 | 2017-04-26 | Life Technologies Corporation | Method for fabricating large scale FET arrays |
| US20100055733A1 (en) | 2008-09-04 | 2010-03-04 | Lutolf Matthias P | Manufacture and uses of reactive microcontact printing of biomolecules on soft hydrogels |
| US20100137143A1 (en) | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| US9080211B2 (en) | 2008-10-24 | 2015-07-14 | Epicentre Technologies Corporation | Transposon end compositions and methods for modifying nucleic acids |
| US20130171621A1 (en) | 2010-01-29 | 2013-07-04 | Advanced Cell Diagnostics Inc. | Methods of in situ detection of nucleic acids |
| EP2354242A1 (en) * | 2010-02-03 | 2011-08-10 | Epiontis GmbH | Assay for determining the type and/or status of a cell based on the epigenetic pattern and the chromatin structure |
| AU2011237729B2 (en) * | 2010-04-05 | 2014-04-03 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| US8951781B2 (en) | 2011-01-10 | 2015-02-10 | Illumina, Inc. | Systems, methods, and apparatuses to image a sample for biological or chemical analysis |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| WO2013019960A1 (en) * | 2011-08-03 | 2013-02-07 | Bio-Rad Laboratories, Inc. | Filtering small nucleic acids using permeabilized cells |
| PT3623481T (en) | 2011-09-23 | 2021-10-15 | Illumina Inc | Methods and compositions for nucleic acid sequencing |
| WO2013096838A2 (en) * | 2011-12-22 | 2013-06-27 | Ibis Biosciences, Inc. | Systems and methods for isolating nucleic acids |
| CA2867665C (en) | 2012-04-03 | 2022-01-04 | Illumina, Inc. | Integrated optoelectronic read head and fluidic cartridge useful for nucleic acid sequencing |
| US9012022B2 (en) | 2012-06-08 | 2015-04-21 | Illumina, Inc. | Polymer coatings |
| US8895249B2 (en) | 2012-06-15 | 2014-11-25 | Illumina, Inc. | Kinetic exclusion amplification of nucleic acid libraries |
| CN113528634A (en) | 2012-08-14 | 2021-10-22 | 10X基因组学有限公司 | Microcapsule compositions and methods |
| US20140378345A1 (en) | 2012-08-14 | 2014-12-25 | 10X Technologies, Inc. | Compositions and methods for sample processing |
| US9783841B2 (en) | 2012-10-04 | 2017-10-10 | The Board Of Trustees Of The Leland Stanford Junior University | Detection of target nucleic acids in a cellular sample |
| EP3901280A1 (en) | 2012-10-17 | 2021-10-27 | Spatial Transcriptomics AB | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
| WO2014085725A1 (en) | 2012-11-27 | 2014-06-05 | Tufts University | Biopolymer-based inks and use thereof |
| US9512422B2 (en) | 2013-02-26 | 2016-12-06 | Illumina, Inc. | Gel patterned surfaces |
| US10138509B2 (en) | 2013-03-12 | 2018-11-27 | President And Fellows Of Harvard College | Method for generating a three-dimensional nucleic acid containing matrix |
| EP2971284A4 (en) * | 2013-03-15 | 2017-01-18 | HTG Molecular Diagnostics, Inc. | Subtyping lung cancers |
| EP4234716A3 (en) | 2013-06-25 | 2023-12-06 | Prognosys Biosciences, Inc. | Methods for determining spatial patterns of biological targets in a sample |
| US20150000854A1 (en) | 2013-06-27 | 2015-01-01 | The Procter & Gamble Company | Sheet products bearing designs that vary among successive sheets, and apparatus and methods for producing the same |
| US10041949B2 (en) | 2013-09-13 | 2018-08-07 | The Board Of Trustees Of The Leland Stanford Junior University | Multiplexed imaging of tissues using mass tags and secondary ion mass spectrometry |
| SG11201604965RA (en) * | 2013-12-20 | 2016-07-28 | Univ Singapore | Differentiation therapy with cd137 ligand agonists |
| CN106460069B (en) | 2014-04-18 | 2021-02-12 | 威廉马歇莱思大学 | Competitive compositions for enriching nucleic acid molecules for rare allele-containing material |
| SG11201610177UA (en) | 2014-06-06 | 2017-01-27 | Herlev Hospital | Determining antigen recognition through barcoding of mhc multimers |
| EP3155426B1 (en) | 2014-06-13 | 2023-07-19 | Immudex ApS | General detection and isolation of specific cells by binding of labeled molecules |
| EP3161160B1 (en) | 2014-06-26 | 2021-10-13 | 10X Genomics, Inc. | Methods of analyzing nucleic acids from individual cells or cell populations |
| US10179932B2 (en) | 2014-07-11 | 2019-01-15 | President And Fellows Of Harvard College | Methods for high-throughput labelling and detection of biological features in situ using microscopy |
| AU2015319825A1 (en) * | 2014-09-26 | 2017-04-27 | Nooma Bio, Inc. | Target sequence detection by nanopore sensing of synthetic probes |
| US20160108458A1 (en) | 2014-10-06 | 2016-04-21 | The Board Of Trustees Of The Leland Stanford Junior University | Multiplexed detection and quantification of nucleic acids in single-cells |
| WO2016138496A1 (en) | 2015-02-27 | 2016-09-01 | Cellular Research, Inc. | Spatially addressable molecular barcoding |
| US11535882B2 (en) * | 2015-03-30 | 2022-12-27 | Becton, Dickinson And Company | Methods and compositions for combinatorial barcoding |
| CA2982146A1 (en) | 2015-04-10 | 2016-10-13 | Spatial Transcriptomics Ab | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| US10059990B2 (en) | 2015-04-14 | 2018-08-28 | Massachusetts Institute Of Technology | In situ nucleic acid sequencing of expanded biological samples |
| EP3283641B1 (en) | 2015-04-14 | 2019-11-27 | Koninklijke Philips N.V. | Spatial mapping of molecular profiles of biological tissue samples |
| EP3325650B1 (en) | 2015-07-17 | 2024-01-03 | Nanostring Technologies, Inc. | Simultaneous quantification of gene expression in a user-defined region of a cross-sectioned tissue |
| AU2016298158B2 (en) | 2015-07-27 | 2019-07-11 | Illumina, Inc. | Spatial mapping of nucleic acid sequence information |
| WO2017027368A1 (en) | 2015-08-07 | 2017-02-16 | Massachusetts Institute Of Technology | Protein retention expansion microscopy |
| EP3332029B1 (en) | 2015-08-07 | 2021-10-06 | Massachusetts Institute of Technology | Nanoscale imaging of proteins and nucleic acids via expansion microscopy |
| CN108431232B (en) | 2015-12-04 | 2022-10-14 | 10X 基因组学有限公司 | Methods and compositions for nucleic acid analysis |
| US20170241911A1 (en) | 2016-02-22 | 2017-08-24 | Miltenyi Biotec Gmbh | Automated analysis tool for biological specimens |
| WO2017147483A1 (en) | 2016-02-26 | 2017-08-31 | The Board Of Trustees Of The Leland Stanford Junior University | Multiplexed single molecule rna visualization with a two-probe proximity ligation system |
| US20170253918A1 (en) | 2016-03-01 | 2017-09-07 | Expansion Technologies | Combining protein barcoding with expansion microscopy for in-situ, spatially-resolved proteomics |
| SG11201807444PA (en) * | 2016-03-10 | 2018-09-27 | Univ Leland Stanford Junior | Transposase-mediated imaging of the accessible genome |
| WO2017161251A1 (en) | 2016-03-17 | 2017-09-21 | President And Fellows Of Harvard College | Methods for detecting and identifying genomic nucleic acids |
| US20180052081A1 (en) | 2016-05-11 | 2018-02-22 | Expansion Technologies | Combining modified antibodies with expansion microscopy for in-situ, spatially-resolved proteomics |
| US10894990B2 (en) * | 2016-05-17 | 2021-01-19 | Shoreline Biome, Llc | High throughput method for identification and sequencing of unknown microbial and eukaryotic genomes from complex mixtures |
| WO2017222453A1 (en) | 2016-06-21 | 2017-12-28 | Hauling Thomas | Nucleic acid sequencing |
| CN109789228B (en) | 2016-07-27 | 2022-10-21 | 斯坦福大学托管董事会 | Highly multiplexed fluorescence imaging |
| CN109923216B (en) | 2016-08-31 | 2024-08-02 | 哈佛学院董事及会员团体 | Method of combining detection of biomolecules into a single assay using fluorescence in situ sequencing |
| CN109983125B (en) | 2016-08-31 | 2024-06-04 | 哈佛学院董事及会员团体 | Method for generating a library of nucleic acid sequences for detection by fluorescence in situ sequencing |
| US11505819B2 (en) | 2016-09-22 | 2022-11-22 | William Marsh Rice University | Molecular hybridization probes for complex sequence capture and analysis |
| WO2018075693A1 (en) | 2016-10-19 | 2018-04-26 | 10X Genomics, Inc. | Methods and systems for barcoding nucleic acid molecules from individual cells or cell populations |
| GB201619458D0 (en) | 2016-11-17 | 2017-01-04 | Spatial Transcriptomics Ab | Method for spatial tagging and analysing nucleic acids in a biological specimen |
| US10656144B2 (en) | 2016-12-02 | 2020-05-19 | The Charlotte Mecklenburg Hospital Authority | Immune profiling and minimal residue disease following stem cell transplantation in multiple myeloma |
| CN110050071A (en) | 2016-12-09 | 2019-07-23 | 乌尔蒂维尤股份有限公司 | The improved method that nucleic acid preparation for using label carries out multiplexing imaging |
| US10995361B2 (en) | 2017-01-23 | 2021-05-04 | Massachusetts Institute Of Technology | Multiplexed signal amplified FISH via splinted ligation amplification and sequencing |
| CA3078158A1 (en) | 2017-10-06 | 2019-04-11 | Cartana Ab | Rna templated ligation |
| WO2019075091A1 (en) | 2017-10-11 | 2019-04-18 | Expansion Technologies | Multiplexed in situ hybridization of tissue sections for spatially resolved transcriptomics with expansion microscopy |
| CN110462060B (en) | 2017-12-08 | 2022-05-03 | 10X基因组学有限公司 | Methods and compositions for labeling cells |
-
2019
- 2019-08-27 CN CN201980071233.1A patent/CN113767175A/en active Pending
- 2019-08-27 EP EP19773222.5A patent/EP3844305A2/en active Pending
- 2019-08-27 SG SG11202102019UA patent/SG11202102019UA/en unknown
- 2019-08-27 WO PCT/US2019/048425 patent/WO2020047002A1/en unknown
- 2019-08-27 EP EP19765928.7A patent/EP3844304A2/en active Pending
- 2019-08-27 EP EP19773221.7A patent/EP3844307A1/en active Pending
- 2019-08-27 US US17/271,995 patent/US20210332425A1/en active Pending
- 2019-08-27 CN CN201980071274.0A patent/CN113366117A/en active Pending
- 2019-08-27 US US18/023,257 patent/US20230323447A1/en active Pending
- 2019-08-27 EP EP19773224.1A patent/EP3844306A2/en active Pending
- 2019-08-27 WO PCT/US2019/048427 patent/WO2020047004A2/en unknown
- 2019-08-27 SG SG11202101944RA patent/SG11202101944RA/en unknown
- 2019-08-27 US US17/271,979 patent/US20210332424A1/en active Pending
- 2019-08-27 SG SG11202102029TA patent/SG11202102029TA/en unknown
- 2019-08-27 WO PCT/US2019/048430 patent/WO2020047007A2/en unknown
- 2019-08-27 SG SG11202102003TA patent/SG11202102003TA/en unknown
- 2019-08-27 WO PCT/US2019/048434 patent/WO2020047010A2/en unknown
- 2019-08-27 CN CN201980071234.6A patent/CN113286893A/en active Pending
-
2020
- 2020-05-18 US US16/876,709 patent/US20210010070A1/en not_active Abandoned
- 2020-05-18 US US16/876,682 patent/US20200407781A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020047010A8 (en) | 2021-08-26 |
| WO2020047002A4 (en) | 2020-04-30 |
| EP3844305A2 (en) | 2021-07-07 |
| US20210332424A1 (en) | 2021-10-28 |
| CN113286893A (en) | 2021-08-20 |
| US20200407781A1 (en) | 2020-12-31 |
| WO2020047007A2 (en) | 2020-03-05 |
| EP3844307A1 (en) | 2021-07-07 |
| US20230323447A1 (en) | 2023-10-12 |
| SG11202101944RA (en) | 2021-03-30 |
| WO2020047010A2 (en) | 2020-03-05 |
| WO2020047007A4 (en) | 2020-07-16 |
| SG11202102019UA (en) | 2021-03-30 |
| US20210010070A1 (en) | 2021-01-14 |
| CN113767175A (en) | 2021-12-07 |
| CN113366117A (en) | 2021-09-07 |
| WO2020047010A3 (en) | 2020-04-16 |
| WO2020047004A2 (en) | 2020-03-05 |
| US20210332425A1 (en) | 2021-10-28 |
| SG11202102003TA (en) | 2021-03-30 |
| WO2020047007A3 (en) | 2020-04-16 |
| WO2020047002A1 (en) | 2020-03-05 |
| WO2020047004A3 (en) | 2020-04-30 |
| EP3844306A2 (en) | 2021-07-07 |
| WO2020047010A4 (en) | 2020-07-16 |
| EP3844304A2 (en) | 2021-07-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG11202102029TA (en) | Methods for generating spatially barcoded arrays | |
| IL254630B (en) | Beamformer for end-to-end beamforming | |
| LT3474669T (en) | Methods for generating barcoded combinatorial libraries | |
| IL257516B (en) | Reference array holder | |
| GB2563314B (en) | Seating Apparatus | |
| IL268641A (en) | Method for generating t cells progenitors | |
| IL284444A (en) | Multi-beam inspection apparatus | |
| GB2575406B (en) | Support beam | |
| ZA202000462B (en) | Apparatus for generating energy | |
| IL277822A (en) | Multi-beam inspection apparatus | |
| HUE047967T2 (en) | Support beam | |
| GB201813457D0 (en) | Probe arrays | |
| SG11201708665VA (en) | Method for generating multiple free seismic images | |
| GB201617864D0 (en) | Marine surveys conducted with multiple source arrays | |
| GB201718751D0 (en) | Welding apparatus | |
| GB2586215B (en) | Seating apparatus | |
| GB201908326D0 (en) | Probe arrays | |
| HK1252508A1 (en) | An apparatus for combining light beams | |
| GB201714001D0 (en) | Method for generating new zeolites | |
| GB201713838D0 (en) | Method for generating new zeolites | |
| GB201712238D0 (en) | Method for generating new zeolites | |
| GB201811221D0 (en) | Jig apparatus | |
| GB201817249D0 (en) | Tuned seismic source arrays | |
| HK1255449A1 (en) | Rapid accounting statement generation method | |
| ZAF201801591S (en) | Beam |