SG11202100710TA - Prolonged administration of a bispecific antibody construct binding to cd33 and cd3 - Google Patents

Prolonged administration of a bispecific antibody construct binding to cd33 and cd3

Info

Publication number
SG11202100710TA
SG11202100710TA SG11202100710TA SG11202100710TA SG11202100710TA SG 11202100710T A SG11202100710T A SG 11202100710TA SG 11202100710T A SG11202100710T A SG 11202100710TA SG 11202100710T A SG11202100710T A SG 11202100710TA SG 11202100710T A SG11202100710T A SG 11202100710TA
Authority
SG
Singapore
Prior art keywords
bispecific antibody
antibody construct
prolonged administration
construct binding
binding
Prior art date
Application number
SG11202100710TA
Inventor
Dirk Nagorsen
Bhakti Mehta
Peter Kufer
Roman Kischel
Sophia K Khaldoyanidi
Original Assignee
Amgen Res Munich Gmbh
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Res Munich Gmbh, Amgen Inc filed Critical Amgen Res Munich Gmbh
Publication of SG11202100710TA publication Critical patent/SG11202100710TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
SG11202100710TA 2018-07-30 2019-07-29 Prolonged administration of a bispecific antibody construct binding to cd33 and cd3 SG11202100710TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862712147P 2018-07-30 2018-07-30
PCT/EP2019/070343 WO2020025532A1 (en) 2018-07-30 2019-07-29 Prolonged administration of a bispecific antibody construct binding to cd33 and cd3

Publications (1)

Publication Number Publication Date
SG11202100710TA true SG11202100710TA (en) 2021-02-25

Family

ID=67513506

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202100710TA SG11202100710TA (en) 2018-07-30 2019-07-29 Prolonged administration of a bispecific antibody construct binding to cd33 and cd3

Country Status (12)

Country Link
US (1) US20210301017A1 (en)
EP (1) EP3830121A1 (en)
JP (1) JP2021532140A (en)
CN (1) CN112771075A (en)
AU (1) AU2019313444A1 (en)
CA (1) CA3107186A1 (en)
IL (1) IL280275A (en)
MA (1) MA53325A (en)
MX (1) MX2021001221A (en)
SG (1) SG11202100710TA (en)
TW (1) TW202021616A (en)
WO (1) WO2020025532A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021083467A1 (en) * 2019-10-28 2021-05-06 Y-Mabs Therapeutics, Inc. Administration of cd22, cd33 and/or tim-3 antibodies using ommaya reservoirs for the treatment of cns cancer or neurodegenerative diseases
US20230146593A1 (en) 2020-03-12 2023-05-11 Amgen Inc. Method for treatment and prophylaxis of crs in patients comprising a combination of bispecific antibodies binding to cds x cancer cell and tnf alpha or il-6 inhibitor
TW202210101A (en) * 2020-05-29 2022-03-16 美商安進公司 Adverse effects-mitigating administration of a bispecific construct binding to cd33 and cd3

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Also Published As

Publication number Publication date
TW202021616A (en) 2020-06-16
MX2021001221A (en) 2021-06-23
MA53325A (en) 2021-06-09
CA3107186A1 (en) 2020-02-06
CN112771075A (en) 2021-05-07
AU2019313444A1 (en) 2021-02-18
US20210301017A1 (en) 2021-09-30
WO2020025532A1 (en) 2020-02-06
JP2021532140A (en) 2021-11-25
EP3830121A1 (en) 2021-06-09
IL280275A (en) 2021-03-01

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