SG11202009695QA - Anti-hla-g antibodies and use thereof - Google Patents

Anti-hla-g antibodies and use thereof

Info

Publication number
SG11202009695QA
SG11202009695QA SG11202009695QA SG11202009695QA SG11202009695QA SG 11202009695Q A SG11202009695Q A SG 11202009695QA SG 11202009695Q A SG11202009695Q A SG 11202009695QA SG 11202009695Q A SG11202009695Q A SG 11202009695QA SG 11202009695Q A SG11202009695Q A SG 11202009695QA
Authority
SG
Singapore
Prior art keywords
hla
antibodies
Prior art date
Application number
SG11202009695QA
Inventor
Stefan Dengl
Sebastian Fenn
Jens Fischer
Andreas Hinz
Claudia Kirstenpfad
Stefan Klostermann
Joerg Moelleken
Georg Tiefenthaler
Sabine Hoves
Alexander Bujotzek
Meher Majety
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG11202009695QA publication Critical patent/SG11202009695QA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11202009695QA 2018-04-18 2019-04-17 Anti-hla-g antibodies and use thereof SG11202009695QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18168011 2018-04-18
PCT/EP2019/060007 WO2019202040A1 (en) 2018-04-18 2019-04-17 Anti-hla-g antibodies and use thereof

Publications (1)

Publication Number Publication Date
SG11202009695QA true SG11202009695QA (en) 2020-11-27

Family

ID=62025723

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202009695QA SG11202009695QA (en) 2018-04-18 2019-04-17 Anti-hla-g antibodies and use thereof

Country Status (20)

Country Link
US (1) US20210147553A1 (en)
EP (1) EP3781593A1 (en)
JP (1) JP7186239B2 (en)
KR (1) KR102608672B1 (en)
CN (1) CN112004831B (en)
AR (1) AR114789A1 (en)
AU (1) AU2019254596A1 (en)
BR (1) BR112020020588A2 (en)
CA (1) CA3094895A1 (en)
CL (1) CL2020002540A1 (en)
CO (1) CO2020012347A2 (en)
CR (1) CR20200483A (en)
IL (1) IL277308A (en)
MA (1) MA52284A (en)
MX (1) MX2020010951A (en)
PE (1) PE20201419A1 (en)
SG (1) SG11202009695QA (en)
TW (1) TW201945395A (en)
WO (1) WO2019202040A1 (en)
ZA (1) ZA202006066B (en)

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TW201829463A (en) 2016-11-18 2018-08-16 瑞士商赫孚孟拉羅股份公司 Anti-hla-g antibodies and use thereof
MX2021000009A (en) 2018-07-09 2021-03-09 Five Prime Therapeutics Inc Antibodies binding to ilt4.
UY38391A (en) 2018-09-27 2020-04-30 Tizona Therapeutics ANTI-HLA-G ANTIBODIES, COMPOSITIONS INCLUDING ANTI-HLA-G ANTIBODIES AND METHODS OF USE OF ANTI HLA-G
CN113528448B (en) * 2020-04-14 2023-01-24 同济大学 Construction method of human embryonic stem cells
JP7326584B2 (en) 2020-12-17 2023-08-15 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト Anti-HLA-G antibody and use thereof
US12012454B2 (en) * 2021-03-24 2024-06-18 China Medical University Hospital Anti-tumor antigen nanobody and nucleic acid encoding sequence thereof, and uses of the same
GB202111905D0 (en) 2021-08-19 2021-10-06 UCB Biopharma SRL Antibodies
WO2023182861A1 (en) * 2022-03-25 2023-09-28 에이치케이이노엔 주식회사 Anti-hla-g chimeric antigen receptor, and use thereof
WO2023182866A1 (en) * 2022-03-25 2023-09-28 에이치케이이노엔 주식회사 Hla-g-specific antibody and use thereof
CN115894687B (en) * 2022-03-31 2024-06-07 台州恩泽医疗中心(集团) Monoclonal antibody for resisting HLA-G1, -G2, -G5 and HLA-G6 isomer molecules and application thereof
WO2024108568A1 (en) * 2022-11-25 2024-05-30 深圳先进技术研究院 Anti-human leukocyte antigen-g nanobody, and preparation method therefor and use thereof
WO2024188966A1 (en) 2023-03-13 2024-09-19 F. Hoffmann-La Roche Ag Treatment of cancer using an anti-hla-g/anti-cd3 bispecific antibody and a 4‑1bb (cd137) agonist
WO2024188965A1 (en) 2023-03-13 2024-09-19 F. Hoffmann-La Roche Ag Combination therapy employing a pd1-lag3 bispecific antibody and an hla-g t cell bispecific antibody

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Also Published As

Publication number Publication date
TW201945395A (en) 2019-12-01
CO2020012347A2 (en) 2020-10-30
BR112020020588A2 (en) 2021-01-12
AU2019254596A1 (en) 2020-10-29
MA52284A (en) 2021-02-24
CL2020002540A1 (en) 2021-01-22
WO2019202040A1 (en) 2019-10-24
CA3094895A1 (en) 2019-10-24
AR114789A1 (en) 2020-10-14
JP7186239B2 (en) 2022-12-08
CN112004831A (en) 2020-11-27
KR20210005080A (en) 2021-01-13
US20210147553A1 (en) 2021-05-20
CR20200483A (en) 2020-11-17
MX2020010951A (en) 2020-11-09
EP3781593A1 (en) 2021-02-24
CN112004831B (en) 2024-04-09
KR102608672B1 (en) 2023-11-30
JP2021521791A (en) 2021-08-30
ZA202006066B (en) 2021-09-29
IL277308A (en) 2020-10-29
PE20201419A1 (en) 2020-12-09

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