SG11202009581TA - Cex chromatography media and low salt elution of target proteins from biopharmaceutical feeds - Google Patents
Cex chromatography media and low salt elution of target proteins from biopharmaceutical feedsInfo
- Publication number
- SG11202009581TA SG11202009581TA SG11202009581TA SG11202009581TA SG11202009581TA SG 11202009581T A SG11202009581T A SG 11202009581TA SG 11202009581T A SG11202009581T A SG 11202009581TA SG 11202009581T A SG11202009581T A SG 11202009581TA SG 11202009581T A SG11202009581T A SG 11202009581TA
- Authority
- SG
- Singapore
- Prior art keywords
- biopharmaceutical
- feeds
- target proteins
- low salt
- chromatography media
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
- B01D15/362—Cation-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862651878P | 2018-04-03 | 2018-04-03 | |
PCT/EP2019/057497 WO2019192877A1 (en) | 2018-04-03 | 2019-03-26 | Cex chromatography media and low salt elution of target proteins from biopharmaceutical feeds |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202009581TA true SG11202009581TA (en) | 2020-10-29 |
Family
ID=65955215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202009581TA SG11202009581TA (en) | 2018-04-03 | 2019-03-26 | Cex chromatography media and low salt elution of target proteins from biopharmaceutical feeds |
Country Status (8)
Country | Link |
---|---|
US (1) | US20210024573A1 (en) |
EP (1) | EP3773969A1 (en) |
JP (1) | JP2021519339A (en) |
KR (1) | KR20200138346A (en) |
CN (1) | CN112105430A (en) |
CA (1) | CA3095850A1 (en) |
SG (1) | SG11202009581TA (en) |
WO (1) | WO2019192877A1 (en) |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ547315A (en) | 2003-10-27 | 2008-07-31 | Wyeth Corp | |
TWI391399B (en) * | 2005-05-25 | 2013-04-01 | Hoffmann La Roche | Method for determining the concentration of a salt for eluting a polypeptide |
CA2687930C (en) * | 2007-05-25 | 2016-05-17 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Graft copolymers for cation exchange chromatography |
KR101226353B1 (en) * | 2007-06-01 | 2013-01-24 | 에프. 호프만-라 로슈 아게 | Immunoglobulin purification |
EP2285485B1 (en) * | 2008-05-30 | 2014-04-23 | Merck Patent GmbH | Ce(iv)-initiated graft polymerization on polymers not containing hydroxyl groups |
EP2153877A1 (en) * | 2008-07-30 | 2010-02-17 | MERCK PATENT GmbH | Mixed graft polymers for ion exchange chromatography |
CN104801204B (en) * | 2009-02-27 | 2019-01-01 | Emd密理博公司 | For removing the film with sulfonic acid group of protein aggregate |
US8945895B2 (en) * | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
EP2598223B1 (en) * | 2010-07-30 | 2022-04-06 | EMD Millipore Corporation | Chromatography media and method |
SG10201701224UA (en) * | 2012-03-12 | 2017-04-27 | Merck Patent Gmbh | Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode |
WO2013180647A1 (en) * | 2012-05-31 | 2013-12-05 | Agency For Science, Technology And Research | Chromatographic purification of immunoglobulin g preparations with particles having multimodal functionalities |
US20150266919A1 (en) * | 2012-10-18 | 2015-09-24 | Jnc Corporation | Cation exchange chromatography carrier for refining of antibodies, and method for separation of antibody monomers from polymers thereof produced in antibody drug manufacturing process |
EP3160611A4 (en) * | 2014-06-25 | 2018-02-28 | JHL Biotech, Inc. | Methods and reagents for purification of proteins |
-
2019
- 2019-03-26 EP EP19714171.6A patent/EP3773969A1/en not_active Withdrawn
- 2019-03-26 CN CN201980031425.XA patent/CN112105430A/en active Pending
- 2019-03-26 CA CA3095850A patent/CA3095850A1/en not_active Abandoned
- 2019-03-26 WO PCT/EP2019/057497 patent/WO2019192877A1/en unknown
- 2019-03-26 JP JP2020554125A patent/JP2021519339A/en active Pending
- 2019-03-26 KR KR1020207031260A patent/KR20200138346A/en not_active Application Discontinuation
- 2019-03-26 SG SG11202009581TA patent/SG11202009581TA/en unknown
- 2019-03-26 US US17/044,428 patent/US20210024573A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20210024573A1 (en) | 2021-01-28 |
WO2019192877A1 (en) | 2019-10-10 |
EP3773969A1 (en) | 2021-02-17 |
CN112105430A (en) | 2020-12-18 |
CA3095850A1 (en) | 2019-10-10 |
KR20200138346A (en) | 2020-12-09 |
JP2021519339A (en) | 2021-08-10 |
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