SG11202004568UA - Minimally invasive collection probe and methods for the use thereof - Google Patents

Minimally invasive collection probe and methods for the use thereof

Info

Publication number
SG11202004568UA
SG11202004568UA SG11202004568UA SG11202004568UA SG11202004568UA SG 11202004568U A SG11202004568U A SG 11202004568UA SG 11202004568U A SG11202004568U A SG 11202004568UA SG 11202004568U A SG11202004568U A SG 11202004568UA SG 11202004568U A SG11202004568U A SG 11202004568UA
Authority
SG
Singapore
Prior art keywords
methods
minimally invasive
collection probe
invasive collection
probe
Prior art date
Application number
SG11202004568UA
Inventor
Livia Eberlin
Thomas Milner
Jialing Zhang
Noah Giese
Nitesh Katta
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Publication of SG11202004568UA publication Critical patent/SG11202004568UA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4055Concentrating samples by solubility techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/313Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes
    • A61B1/3132Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes for laparoscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0283Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/04Endoscopic instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/28Surgical forceps
    • A61B17/29Forceps for use in minimally invasive surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/30Surgical robots
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/4833Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0404Capillaries used for transferring samples or ions
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0459Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for solid samples
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/10Ion sources; Ion guns
    • H01J49/16Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165Electrospray ionisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/06Biopsy forceps, e.g. with cup-shaped jaws
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937Visible markers
    • A61B2090/395Visible markers with marking agent for marking skin or other tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3983Reference marker arrangements for use with image guided surgery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Robotics (AREA)
  • Plasma & Fusion (AREA)
  • Ophthalmology & Optometry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Endoscopes (AREA)
SG11202004568UA 2017-11-27 2018-11-27 Minimally invasive collection probe and methods for the use thereof SG11202004568UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762591179P 2017-11-27 2017-11-27
US201862640385P 2018-03-08 2018-03-08
PCT/US2018/062625 WO2019104328A1 (en) 2017-11-27 2018-11-27 Minimally invasive collection probe and methods for the use thereof

Publications (1)

Publication Number Publication Date
SG11202004568UA true SG11202004568UA (en) 2020-06-29

Family

ID=66630809

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202004568UA SG11202004568UA (en) 2017-11-27 2018-11-27 Minimally invasive collection probe and methods for the use thereof

Country Status (11)

Country Link
US (2) US20200305723A1 (en)
EP (1) EP3717901A4 (en)
JP (1) JP2021504703A (en)
CN (1) CN111566481A (en)
AU (1) AU2018373391A1 (en)
BR (1) BR112020010416A2 (en)
CA (1) CA3083260A1 (en)
IL (1) IL274759A (en)
MX (1) MX2020005448A (en)
SG (1) SG11202004568UA (en)
WO (1) WO2019104328A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109789420B (en) 2016-09-02 2021-09-24 得克萨斯大学体系董事会 Collection probes and methods of use thereof
US20210343515A1 (en) * 2017-06-08 2021-11-04 Board Of Regents, The University Of Texas System Systems and methods for microarray droplet ionization analysis
JP2021504703A (en) 2017-11-27 2021-02-15 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム Minimally invasive collection probe and how to use it
US12089932B2 (en) 2018-06-05 2024-09-17 Trace Matters Scientific Llc Apparatus, system, and method for transferring ions
US11219393B2 (en) 2018-07-12 2022-01-11 Trace Matters Scientific Llc Mass spectrometry system and method for analyzing biological samples
EP3914891A4 (en) * 2019-01-25 2022-09-28 Board of Regents, The University of Texas System Apparatus and methods for cleaning and/or exchanging medical devices
EP4143563A4 (en) * 2020-04-27 2024-05-15 Board of Regents, The University of Texas System Detecting chemical compounds for forensic analysis
EP4143559A4 (en) * 2020-04-29 2023-10-25 MS Pen Technologies, Inc. Collecting and analyzing swab samples
US20220257101A1 (en) * 2021-02-13 2022-08-18 Board Of Regents, The University Of Texas System Miniature hyperspectral imaging
CN113842210A (en) * 2021-08-02 2021-12-28 应葵 Vertebral tumor microwave ablation operation simulation method and device

Family Cites Families (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0369012A4 (en) * 1987-07-23 1990-12-27 Terumo Kabushiki Kaisha Catheter tube
US5711816A (en) * 1990-07-06 1998-01-27 Advanced Technolgy Materials, Inc. Source reagent liquid delivery apparatus, and chemical vapor deposition system comprising same
US5119827A (en) 1990-09-05 1992-06-09 Board Of Regents, The University Of Texas System Mechanisms of antiestrogen resistance in breast cancer
US5100402A (en) 1990-10-05 1992-03-31 Megadyne Medical Products, Inc. Electrosurgical laparoscopic cauterization electrode
US5241990A (en) * 1992-07-10 1993-09-07 Inlet Medical, Inc. Irrigation/aspiration valve and probe for laparoscopy
US5470308A (en) 1992-08-12 1995-11-28 Vidamed, Inc. Medical probe with biopsy stylet
US5746720A (en) * 1995-10-18 1998-05-05 Stouder, Jr.; Albert E. Method and apparatus for insertion of a cannula and trocar
US5742050A (en) 1996-09-30 1998-04-21 Aviv Amirav Method and apparatus for sample introduction into a mass spectrometer for improving a sample analysis
US6297499B1 (en) 1997-07-17 2001-10-02 John B Fenn Method and apparatus for electrospray ionization
US6786884B1 (en) * 1999-10-29 2004-09-07 Bard Access Systems, Inc. Bolus tip design for a multi-lumen catheter
DE60038033T2 (en) 1999-10-29 2009-04-23 MDS Inc. doing business through its MDS Sciex Division, Concord ATMOSPHERE PRINT PHOTOIONISATION: A NEW IONIZATION PROCESS FOR LIQUID CHROMATOGRAPHIC MASS SPECTROMETRY
CN1262337C (en) 2000-11-16 2006-07-05 赛弗根生物系统股份有限公司 Method for analyzing mass spectra
US6784439B2 (en) 2001-07-19 2004-08-31 Ut Battelle, Llc Thin-channel electrospray emitter
US20040014227A1 (en) * 2002-01-04 2004-01-22 Frederick Erik D. Apparatus, method and computer program product for automated high-throughput sampling and data acquisition
US6803566B2 (en) 2002-04-16 2004-10-12 Ut-Battelle, Llc Sampling probe for microarray read out using electrospray mass spectrometry
JP4095349B2 (en) 2002-06-03 2008-06-04 ペンタックス株式会社 Fluorescence measuring device
US6677593B1 (en) 2002-08-28 2004-01-13 Ut-Battelle, Llc Planar flow-by electrode capacitive electrospray ion source
CA2433205A1 (en) 2003-03-18 2004-09-18 James Alexander Keenan Drug delivery, bodily fluid drainage, and biopsy device with enhanced ultrasonic visibility
US7684934B2 (en) 2003-06-06 2010-03-23 The United States Of America As Represented By The Department Of Health And Human Services Pattern recognition of whole cell mass spectra
US7335897B2 (en) 2004-03-30 2008-02-26 Purdue Research Foundation Method and system for desorption electrospray ionization
US7445603B2 (en) 2004-05-12 2008-11-04 Zkz Science Corp. Apparatus for removable distal internal cassette for in situ fixation and specimen processing with serial collection and storage of biopsy specimens
WO2006031842A2 (en) 2004-09-14 2006-03-23 Metara, Inc. In-process mass spectrometry with sample multiplexing
US7295026B2 (en) 2005-06-03 2007-11-13 Ut-Battelle, Llc Automated position control of a surface array relative to a liquid microjunction surface sampler
CA2611591A1 (en) 2005-06-08 2006-12-14 Vanderbilt University Analysis of tissue samples surrounding malignancies
DE102005044307B4 (en) 2005-09-16 2008-04-17 Bruker Daltonik Gmbh Ionization of desorbed molecules
US7714276B2 (en) 2005-09-30 2010-05-11 New York University Methods for direct biomolecule identification by matrix-assisted laser desorption ionization (MALDI) mass spectrometry
JP2009519757A (en) * 2005-12-14 2009-05-21 ストライカー・コーポレイション Medical / surgical waste collection and treatment system
US7544933B2 (en) 2006-01-17 2009-06-09 Purdue Research Foundation Method and system for desorption atmospheric pressure chemical ionization
US7714281B2 (en) 2006-05-26 2010-05-11 Ionsense, Inc. Apparatus for holding solids for use with surface ionization technology
HU226837B1 (en) 2006-05-31 2009-12-28 Semmelweis Egyetem Desorption ionization method and device operated by liquid stream
US7800056B2 (en) 2006-10-26 2010-09-21 Smiths Detection Montreal Inc. Document sampler and method of sampling a document
RU2009123828A (en) 2006-11-23 2010-12-27 Конинклейке Филипс Электроникс Н.В. (Nl) DEVICE FOR ISOLATION AND MALDI ANALYSIS OF ANALYTES IN SAMPLE
US7847244B2 (en) 2006-12-28 2010-12-07 Purdue Research Foundation Enclosed desorption electrospray ionization
US8232521B2 (en) 2007-02-02 2012-07-31 Waters Technologies Corporation Device and method for analyzing a sample
US20080243141A1 (en) 2007-04-02 2008-10-02 Salvatore Privitera Surgical instrument with separate tool head and method of use
EP2160570A4 (en) 2007-06-02 2012-12-05 Cerno Bioscience Llc A self calibration approach for mass spectrometry
EP2235215B1 (en) 2008-01-03 2013-02-20 Board of Regents, The University of Texas System Non-invasive detection of bladder cancer by fluorescence in situ hybridization of aurora a
US9213030B2 (en) 2008-01-28 2015-12-15 National University Of Singapore Lipid tumour profile
CN101959470B (en) * 2008-03-03 2015-07-22 皇家飞利浦电子股份有限公司 Biopsy guidance by electromagnetic tracking and photonic needle
AU2009235924A1 (en) 2008-04-10 2009-10-15 The University Of British Columbia Methods of diagnosing chronic cardiac allograft rejection
US8207494B2 (en) 2008-05-01 2012-06-26 Indiana University Research And Technology Corporation Laser ablation flowing atmospheric-pressure afterglow for ambient mass spectrometry
US8084735B2 (en) 2008-09-25 2011-12-27 Ut-Battelle, Llc Pulsed voltage electrospray ion source and method for preventing analyte electrolysis
WO2010039675A1 (en) 2008-09-30 2010-04-08 Prosolia, Inc. Method and apparatus for embedded heater for desorption and ionization of analytes
EP2380023A2 (en) 2008-12-19 2011-10-26 Medirista Biotechnologies AB Oxidized cardiolipin as a novel pro-inflammatory factor
US20100224013A1 (en) 2009-03-05 2010-09-09 Van Berkel Gary J Method and system for formation and withdrawal of a sample from a surface to be analyzed
WO2010114976A1 (en) 2009-04-01 2010-10-07 Prosolia, Inc. Method and system for surface sampling
CA2759987C (en) 2009-04-30 2018-10-02 Purdue Research Foundation Ion generation using wetted porous material
US9500572B2 (en) 2009-04-30 2016-11-22 Purdue Research Foundation Sample dispenser including an internal standard and methods of use thereof
US8704167B2 (en) 2009-04-30 2014-04-22 Purdue Research Foundation Mass spectrometry analysis of microorganisms in samples
AU2010252652B2 (en) 2009-05-27 2015-05-07 Micromass Uk Limited System and method for identification of biological tissues
WO2010141763A1 (en) 2009-06-03 2010-12-09 Wayne State University Mass spectrometry using laserspray ionization
EP2467868A1 (en) * 2009-08-17 2012-06-27 Temple University Of The Commonwealth System Of Higher Education Vaporization device and method for imaging mass spectrometry
US8546752B2 (en) 2009-12-07 2013-10-01 Advion Inc. Solid-phase extraction (SPE) tips and methods of use
WO2011098509A1 (en) 2010-02-11 2011-08-18 Katholieke Universiteit Leuven Phospholipid profiling and cancer
WO2011127091A1 (en) 2010-04-05 2011-10-13 Indiana University Research And Technology Corporation Method for enhancement of mass resolution over a limited mass range for time-of-flight spectrometry
JP5596402B2 (en) 2010-04-19 2014-09-24 株式会社日立ハイテクノロジーズ Analysis device, ionization device, and analysis method
WO2011140492A2 (en) 2010-05-07 2011-11-10 Ut-Battelle, Llc System and method for extracting a sample from a surface
CN201811941U (en) 2010-05-26 2011-04-27 中国石油化工股份有限公司 Ionization device used for desorption electrospray mass spectrometry (MESI-MS) of liquid sample
EP3719502A1 (en) 2010-06-23 2020-10-07 University of Louisville Research Foundation, Inc. Use of fatty acids in methods for detecting cancer
CA2805249A1 (en) 2010-07-14 2012-01-19 The Regents Of The University Of Colorado, A Body Corporate Methods and systems for in vivo clinical data measurement of analytes
US9153425B2 (en) 2010-09-01 2015-10-06 Ut-Battelle, Llc Device for high spatial resolution chemical analysis of a sample and method of high spatial resolution chemical analysis
EP2612345B1 (en) 2010-09-02 2020-04-08 University of the Sciences in Philadelphia System and method for ionization of molecules for mass spectrometry and ion mobility spectrometry
US8486703B2 (en) 2010-09-30 2013-07-16 Ut-Battelle, Llc Surface sampling concentration and reaction probe
MY164038A (en) 2010-10-29 2017-11-15 Thermo Fisher Scientific Oy System layout for an automated system for sample preparation and analysis
CN102221614B (en) 2011-03-28 2013-07-17 山东大学 Analysis method for identifying effect target of small molecular compound by using gold nanoprobe
US9546979B2 (en) 2011-05-18 2017-01-17 Purdue Research Foundation Analyzing a metabolite level in a tissue sample using DESI
US9157921B2 (en) 2011-05-18 2015-10-13 Purdue Research Foundation Method for diagnosing abnormality in tissue samples by combination of mass spectral and optical imaging
US9024254B2 (en) 2011-06-03 2015-05-05 Purdue Research Foundation Enclosed desorption electrospray ionization probes and method of use thereof
CN109270155B (en) * 2011-12-28 2021-09-10 英国质谱有限公司 System and method for rapid evaporative ionization of liquid phase samples
WO2013112680A1 (en) 2012-01-26 2013-08-01 University Of The Sciences In Philadelphia Ionization at intermediate pressure for atmospheric pressure ionization mass spectrometers
WO2013112836A2 (en) 2012-01-26 2013-08-01 The Cleveland Clinic Foundation Diagnostic and prognostic biomarkers for cancer
US9105458B2 (en) 2012-05-21 2015-08-11 Sarah Trimpin System and methods for ionizing compounds using matrix-assistance for mass spectrometry and ion mobility spectrometry
CN104603289A (en) 2012-06-15 2015-05-06 哈里·斯泰利 Methods of detecting diseases or conditions
WO2014045087A1 (en) 2012-09-20 2014-03-27 Oslo Universitetssykehus Hf Prostate cancer markers and uses thereof
NZ709167A (en) 2012-11-27 2020-03-27 Univ Pontificia Catolica Chile Compositions and methods for diagnosing thyroid tumors
US9568477B2 (en) 2012-12-30 2017-02-14 Brigham And Women's Hospital, Inc. System and method for analysis of bio-metabolites for-use in image-guided surgery
WO2014204638A2 (en) 2013-05-31 2014-12-24 Brigham And Women's Hospital, Inc. System and method for analyzing tissue for the presence of cancer using bio-marker profiles
US10047395B2 (en) 2013-06-26 2018-08-14 Stealth Biotherapeutics Corp Methods and compositions for detecting and diagnosing diseases and conditions
FR3007634B1 (en) * 2013-06-28 2016-09-02 Commissariat Energie Atomique DEVICE FOR IN VIVO COLLECTION OF BIOLOGICAL SPECIES AND AUTOMATED METHOD FOR ANALYZING BIOLOGICAL SPECIES CAPTURED BY MEANS OF SUCH A DEVICE
US9679754B2 (en) * 2013-07-19 2017-06-13 Smiths Detection Inc. Mass spectrometer inlet with reduced average flow
EP3030895B1 (en) * 2013-08-07 2020-12-16 DH Technologies Development PTE. Ltd. Bubble removal from liquid flow into a mass spectrometer source
US9245722B2 (en) 2013-09-16 2016-01-26 Georgia Tech Research Corporation SMS probe and SEM imaging system and methods of use
WO2015061597A1 (en) 2013-10-23 2015-04-30 Brigham And Women's Hospital, Inc. System and method for analyzing tissue intra-operatively using mass spectrometry
JP6577950B2 (en) 2013-12-30 2019-09-18 パーデュー・リサーチ・ファウンデーションPurdue Research Foundation Mass spectrometric probe and system for ionizing a sample
US20150202005A1 (en) * 2014-01-20 2015-07-23 Omniguide, Inc. System and Method To Control Surgical Energy Devices
JP2015171467A (en) 2014-03-12 2015-10-01 セイコーエプソン株式会社 Liquid injection device and surgical equipment
US9297828B2 (en) 2014-03-27 2016-03-29 Ut-Battelle, Llc High heating rate thermal desorption for molecular surface sampling
US9595428B2 (en) 2014-06-17 2017-03-14 The Board Of Regents Of The University Oklahoma Cellular probe device, system and analysis method
US10000789B2 (en) 2014-06-17 2018-06-19 The Board Of Regents Of The University Of Oklahoma Cellular probe device, system and analysis method
US20160041138A1 (en) * 2014-08-11 2016-02-11 Arizona Board Of Regents On Behalf Of Arizona State University Methods for Monitoring Airborne Contaminants and Agents using Atmospheric Condensate
EP3265817B1 (en) 2015-03-06 2020-08-12 Micromass UK Limited Rapid evaporative ionisation mass spectrometry ("reims") and desorption electrospray ionisation mass spectrometry ("desi-ms") analysis of swabs and biopsy samples
CA2978042A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
WO2016142674A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Cell population analysis
JP6800875B2 (en) * 2015-03-06 2020-12-16 マイクロマス ユーケー リミテッド Inflow instrument for ion analyzers connected to rapid evaporation ionized mass spectrometry (“REIMS”) equipment
CN107636794B (en) * 2015-03-06 2020-02-28 英国质谱公司 Liquid trap or separator for electrosurgical applications
GB2552430B (en) 2015-03-06 2022-05-11 Micromass Ltd Collision surface for improved ionisation
US9632066B2 (en) 2015-04-09 2017-04-25 Ut-Battelle, Llc Open port sampling interface
US10060838B2 (en) 2015-04-09 2018-08-28 Ut-Battelle, Llc Capture probe
EP3304033A4 (en) 2015-05-29 2018-11-21 Purdue Research Foundation Methods for analyzing a tissue sample
GB201509402D0 (en) 2015-06-01 2015-07-15 Micromass Ltd Lock mass library for internal correction
US11266383B2 (en) 2015-09-22 2022-03-08 University Health Network System and method for optimized mass spectrometry analysis
US20170097355A1 (en) 2015-10-06 2017-04-06 University Of Washington Biomarkers and methods to distinguish ovarian cancer from benign tumors
GB2548596A (en) 2016-03-22 2017-09-27 Micromass Ltd An interface probe
US20180067097A1 (en) 2016-07-13 2018-03-08 Board Of Regents, The University Of Texas System Molecular markers and methods for sample analysis via mass spectrometry
CN109789420B (en) * 2016-09-02 2021-09-24 得克萨斯大学体系董事会 Collection probes and methods of use thereof
WO2018045208A1 (en) 2016-09-02 2018-03-08 Board Of Regents, The University Of Texas System Collection probe and methods for the use thereof
US10492801B2 (en) * 2016-09-20 2019-12-03 Osteomed Llc Power driven surgical tool
JP2021504703A (en) 2017-11-27 2021-02-15 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム Minimally invasive collection probe and how to use it
US20210033623A1 (en) 2018-02-23 2021-02-04 Board Of Regents, The University Of Texas System Tissue analysis by mass spectrometry

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