SG11202004442VA - Oxoacridinyl acetic acid derivatives and methods of use - Google Patents
Oxoacridinyl acetic acid derivatives and methods of useInfo
- Publication number
- SG11202004442VA SG11202004442VA SG11202004442VA SG11202004442VA SG11202004442VA SG 11202004442V A SG11202004442V A SG 11202004442VA SG 11202004442V A SG11202004442V A SG 11202004442VA SG 11202004442V A SG11202004442V A SG 11202004442VA SG 11202004442V A SG11202004442V A SG 11202004442VA
- Authority
- SG
- Singapore
- Prior art keywords
- oxoacridinyl
- methods
- acetic acid
- acid derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762588820P | 2017-11-20 | 2017-11-20 | |
| US201862631530P | 2018-02-16 | 2018-02-16 | |
| US201862723660P | 2018-08-28 | 2018-08-28 | |
| PCT/US2018/062021 WO2019100061A1 (en) | 2017-11-20 | 2018-11-20 | Oxoacridinyl acetic acid derivatives and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202004442VA true SG11202004442VA (en) | 2020-06-29 |
Family
ID=66540425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202004442VA SG11202004442VA (en) | 2017-11-20 | 2018-11-20 | Oxoacridinyl acetic acid derivatives and methods of use |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10745358B2 (en) |
| EP (1) | EP3713920A4 (en) |
| JP (1) | JP7323539B2 (en) |
| KR (1) | KR20200100081A (en) |
| CN (1) | CN111630036A (en) |
| AU (1) | AU2018368789B2 (en) |
| BR (1) | BR112020009592A2 (en) |
| CA (1) | CA3079262A1 (en) |
| IL (1) | IL274796A (en) |
| MX (1) | MX2020004902A (en) |
| PH (1) | PH12020550652A1 (en) |
| SG (1) | SG11202004442VA (en) |
| WO (1) | WO2019100061A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019046511A1 (en) | 2017-08-31 | 2019-03-07 | Sperovie Biosciences, Inc. | Compounds, compositions, and methods for the treatment of disease |
| WO2020232375A1 (en) * | 2019-05-16 | 2020-11-19 | Silicon Swat, Inc. | Oxoacridinyl acetic acid derivatives and methods of use |
| BR112021024948A2 (en) * | 2019-06-12 | 2022-01-25 | Ryvu Therapeutics S A | Next-generation modulators of interferon gene stimulator (sting) |
| CN112442033A (en) * | 2019-08-28 | 2021-03-05 | 迈德欣国际有限公司 | STING pathway modulators and uses thereof |
| CN112624972A (en) * | 2019-09-24 | 2021-04-09 | 中国人民解放军军事科学院军事医学研究院 | Acridone compound and medical application thereof |
| RU2730530C1 (en) * | 2019-10-29 | 2020-08-24 | Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" | New chemical compound of l-lysine 9-oxoacridinyl-10-acetate, stimulating production of interleukin-24 and tumour necrosis factor - beta |
| CN112778336B (en) * | 2019-11-02 | 2023-05-05 | 上海凌达生物医药有限公司 | Nitrogen-containing condensed ring STING regulator compound, preparation method and application |
| CN111039849B (en) * | 2019-12-26 | 2021-07-06 | 阜阳欣奕华材料科技有限公司 | Preparation method of carbazole ring-containing compound |
| TW202200136A (en) | 2020-04-10 | 2022-01-01 | 日商小野藥品工業股份有限公司 | Cancer treatment method |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3681360A (en) | 1971-04-09 | 1972-08-01 | Hoffmann La Roche | Antiviral substituted acridanones |
| JPH0867873A (en) | 1994-08-29 | 1996-03-12 | Pioneer Electron Corp | Organic electroluminescence element |
| KR19980702644A (en) | 1995-03-02 | 1998-08-05 | 오노다 마사요시 | Novel Quinuclidine Derivatives Having Tricyclic Heterocondensed Rings- |
| WO1997012872A1 (en) | 1995-10-04 | 1997-04-10 | Eisai Co., Ltd. | Acridone compounds |
| US6333322B1 (en) * | 1996-03-13 | 2001-12-25 | Eisai Co., Ltd. | Nitrogen-containing tricyclic compounds and drugs containing the same |
| RU2118532C1 (en) * | 1996-04-10 | 1998-09-10 | Олег Викторович Травкин | Antiinfectious, antiinflammatory and antitumor drug |
| JPH11100373A (en) * | 1997-09-26 | 1999-04-13 | Eisai Co Ltd | New phenothiazine derivative and its medicine |
| RU2197248C2 (en) * | 2001-03-20 | 2003-01-27 | Травкин Олег Викторович | Medicinal preparation eliciting immunomodulating, immunocorrecting, antiparasitic, antisclerotic, antiviral, antibacterial, antifungal, anti-inflammatory and antitumor effect and method of its preparing |
| GB0113435D0 (en) | 2001-06-04 | 2001-07-25 | Amersham Pharm Biotech Uk Ltd | Acridone derivatives as labels for fluorescence detection of target materials |
| GB0113434D0 (en) | 2001-06-04 | 2001-07-25 | Amersham Pharm Biotech Uk Ltd | Quinacridone derivatives as labels for fluorescence detection of biological materials |
| US20070161116A1 (en) | 2003-05-28 | 2007-07-12 | Catherine Copse | Differential analysis of cell surface proteins on closed membrane structures by labelling with dyes in the presence of an internal standard |
| WO2005099656A2 (en) * | 2004-04-06 | 2005-10-27 | The Procter & Gamble Company | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof |
| JP2006004736A (en) | 2004-06-17 | 2006-01-05 | Sumitomo Chemical Co Ltd | Photoelectric transducer and colorant for photoelectric transducer |
| WO2008021745A2 (en) | 2006-08-16 | 2008-02-21 | Itherx Pharmaceuticals, Inc. | Hepatitis c virus entry inhibitors |
| JP2008090130A (en) * | 2006-10-04 | 2008-04-17 | Konica Minolta Medical & Graphic Inc | Photosensitive lithographic printing plate material |
| US20110039289A1 (en) | 2008-03-14 | 2011-02-17 | Pierre Graves | Fluorogenic peptides and their method of production |
| JP2009271403A (en) | 2008-05-09 | 2009-11-19 | Konica Minolta Medical & Graphic Inc | Photosensitive lithographic printing plate material and method for preparing lithographic printing plate |
| JP5717959B2 (en) | 2009-11-17 | 2015-05-13 | 株式会社Adeka | Aromatic sulfonium salt compounds |
| US8618125B2 (en) | 2011-01-14 | 2013-12-31 | Heptiva LLC | Composition comprising hepatic therapeutic active for treating liver diseases, certain cancers and liver health maintenance |
| WO2013022740A2 (en) | 2011-08-05 | 2013-02-14 | Corning Incorporated | Gpr35 ligands and the uses thereof |
| WO2015046502A1 (en) | 2013-09-30 | 2015-04-02 | 富士フイルム株式会社 | Photosensitive resin composition, method for producing cured film, cured film, organic el display device and liquid crystal display device |
| AU2014340269B2 (en) * | 2013-10-21 | 2018-06-21 | Drexel University | Use of STING agonists to treat chronic hepatitis B virus infection |
| CN103709122B (en) | 2013-11-29 | 2016-05-25 | 四川大学 | Antitumor and the antifungal compound being used for the treatment of |
| WO2016179702A1 (en) * | 2015-05-11 | 2016-11-17 | Ranju Ralhan | Acridinone compositions for treating head and neck cancers and methods of prognosing head and neck cancers |
| US11938128B2 (en) | 2017-03-10 | 2024-03-26 | Albert Einstein College Of Medicine | Small molecule BAX inhibitors and uses thereof |
-
2018
- 2018-11-20 KR KR1020207017927A patent/KR20200100081A/en not_active Application Discontinuation
- 2018-11-20 SG SG11202004442VA patent/SG11202004442VA/en unknown
- 2018-11-20 CN CN201880086600.0A patent/CN111630036A/en active Pending
- 2018-11-20 AU AU2018368789A patent/AU2018368789B2/en not_active Ceased
- 2018-11-20 JP JP2020545072A patent/JP7323539B2/en active Active
- 2018-11-20 MX MX2020004902A patent/MX2020004902A/en unknown
- 2018-11-20 WO PCT/US2018/062021 patent/WO2019100061A1/en unknown
- 2018-11-20 US US16/195,997 patent/US10745358B2/en active Active
- 2018-11-20 CA CA3079262A patent/CA3079262A1/en active Pending
- 2018-11-20 BR BR112020009592-3A patent/BR112020009592A2/en unknown
- 2018-11-20 EP EP18878928.3A patent/EP3713920A4/en active Pending
-
2020
- 2020-05-15 PH PH12020550652A patent/PH12020550652A1/en unknown
- 2020-05-20 IL IL274796A patent/IL274796A/en unknown
-
2022
- 2022-07-28 US US17/875,770 patent/US20230113570A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3713920A1 (en) | 2020-09-30 |
| CN111630036A (en) | 2020-09-04 |
| JP7323539B2 (en) | 2023-08-08 |
| US20230113570A1 (en) | 2023-04-13 |
| US20190161449A1 (en) | 2019-05-30 |
| JP2021503501A (en) | 2021-02-12 |
| IL274796A (en) | 2020-07-30 |
| WO2019100061A1 (en) | 2019-05-23 |
| PH12020550652A1 (en) | 2021-04-26 |
| BR112020009592A2 (en) | 2020-11-03 |
| MX2020004902A (en) | 2020-09-09 |
| EP3713920A4 (en) | 2021-04-14 |
| CA3079262A1 (en) | 2019-05-23 |
| AU2018368789A1 (en) | 2020-06-11 |
| US10745358B2 (en) | 2020-08-18 |
| KR20200100081A (en) | 2020-08-25 |
| AU2018368789B2 (en) | 2022-06-02 |
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